ODF2L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ODF2L_HUMAN
• UniProt AC: Q9ULJ1
• Protein Name: Outer dense fiber protein 2-like
• Gene Name: ODF2L
• Organism: Homo sapiens (Human).
• Sequence Length: 636
• Protein Sequence: MEKAVNDGSHSEELFCHLKTISEKEDLPRCTSESHLSCLKQDILNEKTELEATLKEAELVTHSVELLLPLFKDTIEKINFENANLSALNLKISEQKEILIKELDTFKSVKLALEHLLRKRDYKQTGDNLSSMLLENLTDNESENTNLKKKVFEKEAHIQELSCLFQSEKANTLKANRFSQSVKVVHERLQIQIHKREAENDKLKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALKKASKVYKQRLDHFTGAIEKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINLLEDLKKMEDHGKNSCEEILRKVHSIEYENETLNLENTKLKLRFPCRITESKNMNILIVLDMLCYISSEKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTIRELQGQVDGNHNLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEIEKMSSRESALQIKILDLETELRKKNEEQNQLVCKMNSDPETP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	EKAVNDGSHSEELFC CCCCCCCCCCHHHHH	27.06	27966365
11	Phosphorylation	AVNDGSHSEELFCHL CCCCCCCCHHHHHHH	34.17	29449344
19	Ubiquitination	EELFCHLKTISEKED HHHHHHHCCCCCCCC	21.83	29967540
24	Ubiquitination	HLKTISEKEDLPRCT HHCCCCCCCCCCCCC	50.14	-
31	Phosphorylation	KEDLPRCTSESHLSC CCCCCCCCCHHHHHH	36.49	28348404
32	Phosphorylation	EDLPRCTSESHLSCL CCCCCCCCHHHHHHH	40.50	27251275
34	Phosphorylation	LPRCTSESHLSCLKQ CCCCCCHHHHHHHHH	29.51	-
46	Ubiquitination	LKQDILNEKTELEAT HHHHHHCCCCHHHHH	58.89	27667366
74	Phosphorylation	LLPLFKDTIEKINFE HHHHHHHHHHHHCCC	31.46	18452278
77	Ubiquitination	LFKDTIEKINFENAN HHHHHHHHHCCCCCC	38.81	29967540
86	Phosphorylation	NFENANLSALNLKIS CCCCCCCHHEECCHH	30.44	28122231
101	Acetylation	EQKEILIKELDTFKS HCHHHHHHHHCHHHH	49.10	7482777
101	Ubiquitination	EQKEILIKELDTFKS HCHHHHHHHHCHHHH	49.10	29967540
138	Phosphorylation	SMLLENLTDNESENT HHHHHCCCCCCCCCC	48.65	24043423
142	Phosphorylation	ENLTDNESENTNLKK HCCCCCCCCCCCHHH	42.26	21955146
145	Phosphorylation	TDNESENTNLKKKVF CCCCCCCCCHHHHHH	37.57	21955146
169	Ubiquitination	SCLFQSEKANTLKAN HHHHHCHHHHHHHHC	52.78	29967540
177	Ubiquitination	ANTLKANRFSQSVKV HHHHHHCCCCCHHHH	37.14	27667366
213	Ubiquitination	YVKSLETKIAKWNLQ HHHHHHHHHHHHHHH	31.15	29967540
216	Ubiquitination	SLETKIAKWNLQSRM HHHHHHHHHHHHHCC	39.84	27667366
246	Phosphorylation	TVALKKASKVYKQRL HHHHHHHHHHHHHHH	31.37	29083192
262	Ubiquitination	HFTGAIEKLTSQIRD HHHHHHHHHHHHHHH	51.45	-
273	Ubiquitination	QIRDQEAKLSETISA HHHHHHHHHHHHHCC	52.36	29967540
290	Ubiquitination	AWKSHYEKIVIEKTE HHHHHHEEEEEECEE	34.80	29967540
304	Phosphorylation	ELEVQIETMKKQIIN EHHHHHHHHHHHHHH	35.60	28509920
333	Ubiquitination	SCEEILRKVHSIEYE HHHHHHHHHHCCCCC	40.63	29967540
350	Ubiquitination	TLNLENTKLKLRFPC EECCCCCEEEEECCE	56.03	29967540
383	Phosphorylation	YISSEKTTLAALKDE HHCCCCCHHHHHHHH	26.01	-
409	Acetylation	QEVEKKQKTLIEMYK HHHHHHHHHHHHHHH	54.93	20167786
410	Phosphorylation	EVEKKQKTLIEMYKT HHHHHHHHHHHHHHH	30.40	29052541
415	Phosphorylation	QKTLIEMYKTQVQKL HHHHHHHHHHHHHHH	9.70	29052541
416	Acetylation	KTLIEMYKTQVQKLQ HHHHHHHHHHHHHHH	31.04	20167786
417	Phosphorylation	TLIEMYKTQVQKLQE HHHHHHHHHHHHHHH	19.24	29052541
434	Ubiquitination	EIVKSRCENLLHKNN HHHHHHHHHHHHHCC	50.21	29967540
447	Ubiquitination	NNQITKTKNKNVEKM CCCCCHHCCCCHHHH	68.43	29967540
463	Ubiquitination	GQMESHLKELERVCD HHHHHHHHHHHHHHH	55.63	29967540
476	Ubiquitination	CDSLTAAERRLHECQ HHHHHHHHHHHHHHH	35.55	29967540
485 (in isoform 3)	Phosphorylation	-	9.62	-
486	Ubiquitination	LHECQESLQCCKGKC HHHHHHHHHHCCCCC	4.43	29967540
513	Ubiquitination	QVDGNHNLLTKLSLE CCCCCCCCEEECCHH	5.10	29967540
515	Ubiquitination	DGNHNLLTKLSLEEE CCCCCCEEECCHHHC	32.86	29967540
516	Ubiquitination	GNHNLLTKLSLEEEN CCCCCEEECCHHHCC	35.73	-
529	Ubiquitination	ENCLIQLKCENLQQK CCHHHHHHCHHHHHH	24.11	29967540
550	Ubiquitination	ENKELEKKLANQEEC HHHHHHHHHCCHHHH	43.38	-
552	Ubiquitination	KELEKKLANQEECLK HHHHHHHCCHHHHHH	25.25	29967540
568	Ubiquitination	SNLKFKEKSAEYTAL CCCCHHHHHHHHHHH	56.40	29967540
576	Ubiquitination	SAEYTALARQLEAAL HHHHHHHHHHHHHHH	8.49	29967540
589	Ubiquitination	ALEEGRQKVAEEIEK HHHHHHHHHHHHHHH	41.89	-
605	Ubiquitination	SSRESALQIKILDLE CCCHHHHHHHHHHHH	34.35	29967540
631	Phosphorylation	QLVCKMNSDPETP-- CCCHHCCCCCCCC--	51.55	29083192
635	Phosphorylation	KMNSDPETP------ HCCCCCCCC------	39.42	29083192

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ODF2L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ODF2L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ODF2L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ERBB3_HUMAN	ERBB3	physical	16169070
CE126_HUMAN	KIAA1377	physical	16169070
A4_HUMAN	APP	physical	21832049
NPM2_HUMAN	NPM2	physical	28514442
G3PT_HUMAN	GAPDHS	physical	28514442
ZMAT2_HUMAN	ZMAT2	physical	28514442
HACL1_HUMAN	HACL1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.