G3PT_HUMAN - dbPTM
G3PT_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID G3PT_HUMAN
UniProt AC O14556
Protein Name Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
Gene Name GAPDHS
Organism Homo sapiens (Human).
Sequence Length 408
Subcellular Localization Cytoplasm.
Protein Description May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity)..
Protein Sequence MSKRDIVLTNVTVVQLLRQPCPVTRAPPPPEPKAEVEPQPQPEPTPVREEIKPPPPPLPPHPATPPPKMVSVARELTVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNGQLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVISAPSPDAPMFVMGVNENDYNPGSMNIVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHSYTATQKTVDGPSRKAWRDGRGAHQNIIPASTGAAKAVTKVIPELKGKLTGMAFRVPTPDVSVVDLTCRLAQPAPYSAIKEAVKAAAKGPMAGILAYTEDEVVSTDFLGDTHSSIFDAKAGIALNDNFVKLISWYDNEYGYSHRVVDLLRYMFSRDK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
64PhosphorylationPLPPHPATPPPKMVS
CCCCCCCCCCCCEEE		40.5624719451
77PhosphorylationVSVARELTVGINGFG
EEEEEEEEECCCCCC		16.37-
116PhosphorylationIDPEYMVYMFKYDST
CCHHHEEEEEEEECC		4.7430257219
119AcetylationEYMVYMFKYDSTHGR
HHEEEEEEEECCCCE		31.4525038526
151AcetylationEISVYQCKEPKQIPW
EEEEEECCCCCCCCC		62.6225038526
154AcetylationVYQCKEPKQIPWRAV
EEECCCCCCCCCCCC		63.0525038526
225PhosphorylationIVSNASCTTNCLAPL
ECCCCCHHCCCHHHH		20.6724719451
252PhosphorylationGLMTTVHSYTATQKT
HHHHHHHEEECEECC		21.6030622161
254PhosphorylationMTTVHSYTATQKTVD
HHHHHEEECEECCCC		26.6630622161
256PhosphorylationTVHSYTATQKTVDGP
HHHEEECEECCCCCC		23.8530622161
282PhosphorylationHQNIIPASTGAAKAV
CCCCCCCCCCHHHHH		23.2420068231
283PhosphorylationQNIIPASTGAAKAVT
CCCCCCCCCHHHHHH		32.7128985074
287AcetylationPASTGAAKAVTKVIP
CCCCCHHHHHHHHHH		42.7425038526
291AcetylationGAAKAVTKVIPELKG
CHHHHHHHHHHHHCC		31.4125038526
301PhosphorylationPELKGKLTGMAFRVP
HHHCCCEECEEEECC		28.5323911959
303SulfoxidationLKGKLTGMAFRVPTP
HCCCEECEEEECCCC		2.4121406390
309PhosphorylationGMAFRVPTPDVSVVD
CEEEECCCCCCEEEE		29.3030622161
313PhosphorylationRVPTPDVSVVDLTCR
ECCCCCCEEEEEEEE		24.6530622161
318PhosphorylationDVSVVDLTCRLAQPA
CCEEEEEEEECCCCC		7.3621082442
328PhosphorylationLAQPAPYSAIKEAVK
CCCCCCHHHHHHHHH		23.5830622161
384PhosphorylationDNFVKLISWYDNEYG
CCHHHHHEHHHCCCC		29.9822817900
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of G3PT_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of G3PT_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of G3PT_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
A4_HUMANAPPphysical
21832049
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of G3PT_HUMAN

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Related Literatures of Post-Translational Modification

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