CK049_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CK049_HUMAN
• UniProt AC: Q9H6J7
• Protein Name: UPF0705 protein C11orf49
• Gene Name: C11orf49
• Organism: Homo sapiens (Human).
• Sequence Length: 331
• Protein Sequence: MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTEYFNSVCQGTHILFREFSFVQATPHNRVSFLRAFWRCFRTVGKNGDLLTMKEYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYEDLLSGKNPNTVIVPTSSSGQHRQRPALGGAGTLEGVEASLFYQCLENLCDRHKYSCPPPALVKEALSNVQRLTFYGFLMALSKHRGINQALGALPDKGDLMHDPAMDEELERLLAQVPGLVNSVTASPEASCLPSRTPPRVGSPWRPLHHSRKVDGESDGSTEETDESET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MLSPERLALP -----CCCHHHHCCC	24.34	24719451
119	Ubiquitination	FPLELTQKAARIVLM CCHHHHHHHHHHHHC	38.49	-
214 (in isoform 2)	Ubiquitination	-	39.49	-
214	Ubiquitination	ENLCDRHKYSCPPPA HHHHHHHCCCCCCHH	39.49	-
215	Phosphorylation	NLCDRHKYSCPPPAL HHHHHHCCCCCCHHH	14.91	-
224 (in isoform 2)	Ubiquitination	-	37.81	-
224	Ubiquitination	CPPPALVKEALSNVQ CCCHHHHHHHHHHHH	37.81	-
228	Phosphorylation	ALVKEALSNVQRLTF HHHHHHHHHHHHHHH	41.84	19664995
234	Phosphorylation	LSNVQRLTFYGFLMA HHHHHHHHHHHHHHH	19.59	27251275
236	Phosphorylation	NVQRLTFYGFLMALS HHHHHHHHHHHHHHH	11.18	19664995
243	Phosphorylation	YGFLMALSKHRGINQ HHHHHHHHHCCCHHH	19.51	30622161
258 (in isoform 3)	Ubiquitination	-	53.00	21906983
258 (in isoform 1)	Ubiquitination	-	53.00	21906983
258 (in isoform 2)	Ubiquitination	-	53.00	21906983
258	Ubiquitination	ALGALPDKGDLMHDP HHCCCCCCCCCCCCH	53.00	21906983
284	Phosphorylation	QVPGLVNSVTASPEA HCCCHHHCCCCCCCH	17.23	29978859
286	Phosphorylation	PGLVNSVTASPEASC CCHHHCCCCCCCHHC	22.65	21712546
288	Phosphorylation	LVNSVTASPEASCLP HHHCCCCCCCHHCCC	17.57	25159151
292	Phosphorylation	VTASPEASCLPSRTP CCCCCCHHCCCCCCC	17.96	25159151
296	Phosphorylation	PEASCLPSRTPPRVG CCHHCCCCCCCCCCC	35.52	29978859
298	Phosphorylation	ASCLPSRTPPRVGSP HHCCCCCCCCCCCCC	41.82	20068231
304	Phosphorylation	RTPPRVGSPWRPLHH CCCCCCCCCCCCCCC	20.59	27422710
318 (in isoform 4)	Phosphorylation	-	40.99	-
319	Phosphorylation	SRKVDGESDGSTEET CCCCCCCCCCCCCCC	53.45	28985074
320 (in isoform 4)	Phosphorylation	-	51.24	-
322	Phosphorylation	VDGESDGSTEETDES CCCCCCCCCCCCCCC	37.32	28985074
323	Phosphorylation	DGESDGSTEETDESE CCCCCCCCCCCCCCC	43.29	24114839
326	Phosphorylation	SDGSTEETDESET-- CCCCCCCCCCCCC--	38.54	30177828

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CK049_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CK049_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CK049_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RBM48_HUMAN	RBM48	physical	16169070
PSA1_HUMAN	PSMA1	physical	16169070
RL8_HUMAN	RPL8	physical	16169070
RS3A_HUMAN	RPS3A	physical	16169070
CDC16_HUMAN	CDC16	physical	21988832
GSHR_HUMAN	GSR	physical	21988832
PNMA5_HUMAN	PNMA5	physical	25416956
LRC49_HUMAN	LRRC49	physical	26186194
KAPCB_HUMAN	PRKACB	physical	26186194
TPGS2_HUMAN	TPGS2	physical	26186194
NICN1_HUMAN	NICN1	physical	26186194
LRC49_HUMAN	LRRC49	physical	28514442
TPGS2_HUMAN	TPGS2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.