NICN1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NICN1_HUMAN
• UniProt AC: Q9BSH3
• Protein Name: Nicolin-1
• Gene Name: NICN1
• Organism: Homo sapiens (Human).
• Sequence Length: 213
• Subcellular Localization: Nucleus .
• Protein Sequence: MSRVLVPCHVKGSVALQVGDVRTSQGRPGVLVIDVTFPSVAPFELQEITFKNYYTAFLSIRVRQYTSAHTPAKWVTCLRDYCLMPDPHSEEGAQEYVSLFKHQMLCDMARISELRLILRQPSPLWLSFTVEELQIYQQGPKSPSVTFPKWLSHPVPCEQPALLREGLPDPSRVSSEVQQMWALTEMIRASHTSARIGRFDVDGCYDLNLLSYT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
98	Phosphorylation	EGAQEYVSLFKHQML HHHHHHHHHHHHHHH	27.47	24719451
112	Phosphorylation	LCDMARISELRLILR HHHHHHHHHHHHHHC	25.65	20068231
142	Phosphorylation	IYQQGPKSPSVTFPK HHHCCCCCCCCCCCH	26.07	28555341
149	Ubiquitination	SPSVTFPKWLSHPVP CCCCCCCHHHCCCCC	57.48	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NICN1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NICN1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NICN1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CK049_HUMAN	C11orf49	physical	28514442
LRC49_HUMAN	LRRC49	physical	28514442
TTLL1_HUMAN	TTLL1	physical	28514442
TPGS1_HUMAN	TPGS1	physical	28514442
TPGS2_HUMAN	TPGS2	physical	28514442
K1841_HUMAN	KIAA1841	physical	28514442
TBC19_HUMAN	TBC1D19	physical	28514442
SMG8_HUMAN	SMG8	physical	28514442
UBB_HUMAN	UBB	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.