K1841_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: K1841_HUMAN
• UniProt AC: Q6NSI8
• Protein Name: Uncharacterized protein KIAA1841
• Gene Name: KIAA1841
• Organism: Homo sapiens (Human).
• Sequence Length: 718
• Protein Sequence: MSRGYSENNNFLNNNNQMVLDMILYPLIGIPQTINWETIARLVPGLTPKECAKRFDELKSSGSSPVDNQYNSLMAAGESPVETLATYIKSSLLDIHGEFQETPVGHDAVSKTGRHSIASTRNCSSESENCTTHNGGEMTEESEGPNMVIHVCDEAKNLKEDFTCPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYIKRNTKENKDCEMPTLEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVATPCNMNCINANLLTRIADLFSHNEVDDLKDKKDKFKSKLFCKKIERLFDPEYLNPDSRSNAATLYRCCLCKKLLTKETERRIPCIPGKINVDRRGNIVYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTINWLTCSRCYQAFLCIEFSHCQYHSETVVYPTAASSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVTLRDQGEGGDLPSCPTARMLDDLHKYRDVIVVPFSKDTVSDVGVGLCDEKGIECDVLLEPNTPWGPKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEVSKKQRKKEKPKKFTRQPKKQVSSPCAQRKEKALEKSASRDVSPFVMSMQKNKWDATRSLRFNQDAQREDDQRRMTEITGHLIKMRLGDLDRVKSKEAKEFAGGIYSRLEAQIKASVPVSARQSSSEKNTRSKSRFGQGRPA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
116	Phosphorylation	VSKTGRHSIASTRNC CCCCCCCCCCCCCCC	20.63	24719451
124	Phosphorylation	IASTRNCSSESENCT CCCCCCCCCCCCCCC	40.46	-
125	Phosphorylation	ASTRNCSSESENCTT CCCCCCCCCCCCCCC	47.55	-
127	Phosphorylation	TRNCSSESENCTTHN CCCCCCCCCCCCCCC	35.74	-
132	Phosphorylation	SESENCTTHNGGEMT CCCCCCCCCCCCCCC	18.62	-
159	Ubiquitination	CDEAKNLKEDFTCPR CHHHCCCCCCCCCCH	65.71	29967540
207	Phosphorylation	IFNWLIKYIKRNTKE HHHHHHHHHHHHCCC	12.51	-
234	Phosphorylation	NVISILISSEFLKMD CEEEEEECHHHHCCH	21.99	21815630
312	Phosphorylation	ERLFDPEYLNPDSRS HHHCCHHHCCCCCCC	19.71	27642862
458	Acetylation	TQLTKGCKVRDHMVT HHCCCCCEECCCEEE	49.31	20167786
489	Acetylation	RMLDDLHKYRDVIVV HHHHHHHHCCCEEEE	49.64	12439263
500	Acetylation	VIVVPFSKDTVSDVG EEEEECCCCCHHHCC	58.77	12439273
552	Phosphorylation	TLQLKQQSLFSEEEE HHHHHHHHCCCCCCH	28.96	-
562	Phosphorylation	SEEEEYTTGSEVTED CCCCHHCCCCCCCCC	37.50	-
599	Phosphorylation	RQPKKQVSSPCAQRK CCCHHHCCCHHHHHH	26.52	27794612
600	Phosphorylation	QPKKQVSSPCAQRKE CCHHHCCCHHHHHHH	25.74	27794612
613	Phosphorylation	KEKALEKSASRDVSP HHHHHHHHHHCCCHH	23.31	28176443
615	Phosphorylation	KALEKSASRDVSPFV HHHHHHHHCCCHHHH	35.78	28176443
619	Phosphorylation	KSASRDVSPFVMSMQ HHHHCCCHHHHHHHH	19.53	28176443
624	Phosphorylation	DVSPFVMSMQKNKWD CCHHHHHHHHCCCCH	16.86	28176443
670	Trimethylation	LGDLDRVKSKEAKEF CCCHHHHCCHHHHHH	57.62	-
670	Methylation	LGDLDRVKSKEAKEF CCCHHHHCCHHHHHH	57.62	-
672	Methylation	DLDRVKSKEAKEFAG CHHHHCCHHHHHHHC	56.84	-
672	Trimethylation	DLDRVKSKEAKEFAG CHHHHCCHHHHHHHC	56.84	-
682	Phosphorylation	KEFAGGIYSRLEAQI HHHHCHHHHHHHHHH	7.33	-
683	Phosphorylation	EFAGGIYSRLEAQIK HHHCHHHHHHHHHHH	28.59	24719451
694 (in isoform 2)	Phosphorylation	-	16.32	21060948
696	Phosphorylation	IKASVPVSARQSSSE HHHCCCCCCCCCCCC	16.21	-
697 (in isoform 2)	Phosphorylation	-	17.48	24114839
698 (in isoform 2)	Phosphorylation	-	29.43	24114839
700	Phosphorylation	VPVSARQSSSEKNTR CCCCCCCCCCCCCCC	30.22	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of K1841_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of K1841_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of K1841_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.