PNMA5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PNMA5_HUMAN
• UniProt AC: Q96PV4
• Protein Name: Paraneoplastic antigen-like protein 5
• Gene Name: PNMA5
• Organism: Homo sapiens (Human).
• Sequence Length: 448
• Protein Sequence: MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRREDNAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDVARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKEDFRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTPALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEASVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPGREGPQAAGEELGNEAGAGAMSHPKPWET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
49	Phosphorylation	GLQPLCAYRVLGRMF CCHHHHHHHHHHHHH	10.56	-
128	Phosphorylation	ARALGCCSLPAESLD HHHHCCCCCCHHHCC	41.27	27499020
133	Phosphorylation	CCSLPAESLDAEVMP CCCCCHHHCCCCCCC	33.39	27499020
144	Phosphorylation	EVMPQVRSPPLEPPK CCCCCCCCCCCCCCC	31.82	27134283
203	Phosphorylation	KRRRLLESLRGPALS HHHHHHHHCCCHHHH	24.28	28674151
254	Acetylation	RFLQTSPKIGEKVST HHHCCCCCHHHHHHH	64.21	7261991
258	Acetylation	TSPKIGEKVSTFLLR CCCCHHHHHHHHHHH	35.95	7262001
272	Ubiquitination	RLEPLLQKAVHKSPL HHHHHHHHHHHCCCC	52.96	-
277	Phosphorylation	LQKAVHKSPLSVRST HHHHHHCCCCCCCCC	19.05	-
284	Phosphorylation	SPLSVRSTDMIRLKH CCCCCCCCHHHHHHH	21.01	-
299	Phosphorylation	LLARVAMTPALRGKL HHHHHHCCHHHHHHH	8.82	-
343	Ubiquitination	AVMKNKEKPSGRGRG HHHHCCCCCCCCCCC	46.20	-
373	Phosphorylation	QATVQARSFSDSSPQ CCEEEEECCCCCCCC	31.92	27251275
375	Phosphorylation	TVQARSFSDSSPQTI EEEEECCCCCCCCCC	37.52	28258704
377	Phosphorylation	QARSFSDSSPQTIQG EEECCCCCCCCCCCC	42.60	27251275
378	Phosphorylation	ARSFSDSSPQTIQGG EECCCCCCCCCCCCC	26.47	27251275
381	Phosphorylation	FSDSSPQTIQGGLPP CCCCCCCCCCCCCCH	20.74	28258704

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PNMA5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PNMA5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PNMA5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PNMA5_HUMAN	PNMA5	physical	25416956
ZMY19_HUMAN	ZMYND19	physical	25416956
GAPR1_HUMAN	GLIPR2	physical	25416956
CE57L_HUMAN	CEP57L1	physical	25416956
ZBT8A_HUMAN	ZBTB8A	physical	28514442
UACA_HUMAN	UACA	physical	28514442
TF3C2_HUMAN	GTF3C2	physical	28514442
CARME_HUMAN	C9orf41	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.