dbPTM

CE164_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CE164_HUMAN
UniProt AC	Q9UPV0
Protein Name	Centrosomal protein of 164 kDa
Gene Name	CEP164
Organism	Homo sapiens (Human).
Sequence Length	1460
Subcellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Nucleus. Localizes specifically to very distally located appendage structures on the mature centriole from which initiate PC formation (PubMed:26337392). Persisted at cen
Protein Description	Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1..
Protein Sequence	MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPGEWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
104	Phosphorylation	IQERAKLSTSGAIKK HHHHHHCCCCCHHHH	21.59	28450419
105	Phosphorylation	QERAKLSTSGAIKKK HHHHHCCCCCHHHHH	41.43	28450419
106	Phosphorylation	ERAKLSTSGAIKKKK HHHHCCCCCHHHHHH	23.89	28450419
156	Phosphorylation	PLRGLVDTPPSALRG CCCCCCCCCCHHHCC	29.62	20860994
172	Phosphorylation	QSVSLGSSVESGRQL CCCCCCCCCHHHCCC	28.27	-
186	Phosphorylation	LGELMLPSQGLKTSA CCCEECCCCCCCCHH	32.68	23403867
201	Phosphorylation	YTKGLLGSIYEDKTA HHHHHHCHHHCCHHH	23.20	27732954
203	Phosphorylation	KGLLGSIYEDKTALS HHHHCHHHCCHHHHH	21.55	25884760
218	Phosphorylation	LLGLGEETNEEDEEE HCCCCCCCCCCCCHH	43.56	26471730
226	Phosphorylation	NEEDEEESDNQSVHS CCCCCHHCCCCCCCC	45.18	26471730
230	Phosphorylation	EEESDNQSVHSSSEP CHHCCCCCCCCCCCC	28.22	26471730
233	Phosphorylation	SDNQSVHSSSEPLRN CCCCCCCCCCCCHHH	33.14	26471730
234	Phosphorylation	DNQSVHSSSEPLRNL CCCCCCCCCCCHHHC	24.68	26471730
235	Phosphorylation	NQSVHSSSEPLRNLH CCCCCCCCCCHHHCC	46.37	26471730
254	Phosphorylation	ALGGDFEYEESLRTS CCCCCCCHHHHHCCC	25.62	27642862
270	Phosphorylation	PEEKKDVSLDSDAAG CHHHCCCCCCCCCCC	36.27	25159151
273	Phosphorylation	KKDVSLDSDAAGPPT HCCCCCCCCCCCCCC	34.15	25159151
280	Phosphorylation	SDAAGPPTPCKPSSP CCCCCCCCCCCCCCC	44.44	29978859
285	Phosphorylation	PPTPCKPSSPGADSS CCCCCCCCCCCCCCC	34.36	30576142
286	Phosphorylation	PTPCKPSSPGADSSL CCCCCCCCCCCCCCH	35.56	30576142
291	Phosphorylation	PSSPGADSSLSSAVG CCCCCCCCCHHHHCC	32.42	30576142
292	Phosphorylation	SSPGADSSLSSAVGK CCCCCCCCHHHHCCC	32.58	25159151
294	Phosphorylation	PGADSSLSSAVGKGR CCCCCCHHHHCCCCC	20.42	29978859
295	Phosphorylation	GADSSLSSAVGKGRQ CCCCCHHHHCCCCCC	32.06	29978859
319	Phosphorylation	EKEENEKSEPKICRN HHHCCCCCCCCHHHC	53.61	26471730
329	Phosphorylation	KICRNLVTPKADPTG CHHHCCCCCCCCCCC	23.41	23403867
351	Phosphorylation	EKEAPEDTVDAGEEG CCCCCCCCCCCCHHH	20.72	23312004
359	Phosphorylation	VDAGEEGSRREEAAK CCCCHHHHHHHHHHH	31.29	29255136
373	Phosphorylation	KEPKKKASALEEGSS HCHHHHHHHHHHCCC	42.12	29449344
379	Phosphorylation	ASALEEGSSDASQEL HHHHHHCCCCHHHHH	28.46	29449344
380	Phosphorylation	SALEEGSSDASQELE HHHHHCCCCHHHHHH	48.31	29449344
383	Phosphorylation	EEGSSDASQELEISE HHCCCCHHHHHHHHH	29.22	29449344
389	Phosphorylation	ASQELEISEHMKEPQ HHHHHHHHHHCCCCC	16.45	29449344
407	Phosphorylation	SIASDPKSFHGLDFG HHCCCCHHHCCCCCC	28.06	30266825
420	Phosphorylation	FGFRSRISEHLLDVD CCHHHHHHHHCCCHH	20.18	24247654
430	Phosphorylation	LLDVDVLSPVLGGAC CCCHHHHHHHCCHHH	16.89	22199227
452	Phosphorylation	GIEDKDDSQSSQDEL CCCCCCCCCCCHHHH	41.94	27732954
454	Phosphorylation	EDKDDSQSSQDELQS CCCCCCCCCHHHHHH	33.64	27732954
455	Phosphorylation	DKDDSQSSQDELQSK CCCCCCCCHHHHHHH	33.73	27732954
461	Phosphorylation	SSQDELQSKQSKGLE CCHHHHHHHHHHCHH	45.33	27732954
472	Phosphorylation	KGLEERLSPPLPHEE HCHHHHHCCCCCHHH	30.60	23401153
483	Phosphorylation	PHEERAQSPPRSLAT CHHHHCCCCCCCCCC	35.57	27732954
487	Phosphorylation	RAQSPPRSLATEEEP HCCCCCCCCCCCCCC	28.29	27251275
490	Phosphorylation	SPPRSLATEEEPPQG CCCCCCCCCCCCCCC	49.58	27732954
523	Phosphorylation	ASLSLQLSLQREQAP HHHHHHHHHHHHCCC	14.97	24719451
531	Phosphorylation	LQREQAPSPPAACEK HHHHCCCCCHHHHHH	46.67	30108239
544	Phosphorylation	EKGKEQHSQAEELGP HHHHHHHHCHHHHCC	30.68	30108239
566	Phosphorylation	PEEKVAVSPTPPVSP HHHCCCCCCCCCCCC	17.20	25159151
568	Phosphorylation	EKVAVSPTPPVSPEV HCCCCCCCCCCCCCC	32.49	20363803
572	Phosphorylation	VSPTPPVSPEVRSTE CCCCCCCCCCCCCCC	22.55	20363803
577	Phosphorylation	PVSPEVRSTEPVAPP CCCCCCCCCCCCCCH	42.15	26657352
578	Phosphorylation	VSPEVRSTEPVAPPE CCCCCCCCCCCCCHH	33.47	25850435
588	Phosphorylation	VAPPEQLSEAALKAM CCCHHHHCHHHHHHH	25.53	30108239
614	Ubiquitination	QRHLLESKQEKMQQL HHHHHHHHHHHHHHH	53.77	29967540
617	Ubiquitination	LLESKQEKMQQLREK HHHHHHHHHHHHHHH	39.24	29967540
640	Ubiquitination	ILRLHQQKEQSLSSL HHHHHHHHHHHHHHH	51.67	29967540
643	Phosphorylation	LHQQKEQSLSSLRER HHHHHHHHHHHHHHH	31.17	22167270
643	Ubiquitination	LHQQKEQSLSSLRER HHHHHHHHHHHHHHH	31.17	29967540
645	Phosphorylation	QQKEQSLSSLRERLQ HHHHHHHHHHHHHHH	32.35	22167270
646	Phosphorylation	QKEQSLSSLRERLQK HHHHHHHHHHHHHHH	36.42	22167270
735	Phosphorylation	EIEASEKSEQAALNA HHHHHHHHHHHHHHH	30.78	25159151
765	Phosphorylation	ERKEAVATLEKEHSA HHHHHHHHHHHHHHH	28.93	24719451
834	Phosphorylation	GYEHELSSLLREKRQ CHHHHHHHHHHHHHH	44.01	24719451
887	Ubiquitination	LLGHLTGELERLQRA HHHHHHHHHHHHHHH	42.07	16196087
915	Ubiquitination	KRLEDLRRRHREQER HHHHHHHHHHHHHHH	46.16	16196087
955	Ubiquitination	QEETARREKQQLLDV HHHHHHHHHHHHHHH	50.06	21963094
956	Ubiquitination	EETARREKQQLLDVQ HHHHHHHHHHHHHHH	41.34	29967540
959	Ubiquitination	ARREKQQLLDVQRQV HHHHHHHHHHHHHHH	4.01	29967540
969	Ubiquitination	VQRQVALKSEEATAT HHHHHHHHCHHHHHH	46.19	29967540
972	Ubiquitination	QVALKSEEATATHQQ HHHHHCHHHHHHHHH	59.41	29967540
982	Ubiquitination	ATHQQLEEAQKEHTH HHHHHHHHHHHHHHH	66.06	16196087
983	Ubiquitination	THQQLEEAQKEHTHL HHHHHHHHHHHHHHH	19.17	21963094
1002	Ubiquitination	QQLREILDELQARKL HHHHHHHHHHHHHHC	61.29	16196087
1008	Ubiquitination	LDELQARKLKLESQV HHHHHHHHCHHHHHH	53.65	16196087
1010	Ubiquitination	ELQARKLKLESQVDL HHHHHHCHHHHHHHH	53.92	29967540
1011	Ubiquitination	LQARKLKLESQVDLL HHHHHCHHHHHHHHH	12.72	16196087
1013	Phosphorylation	ARKLKLESQVDLLQA HHHCHHHHHHHHHHH	46.04	-
1013	Ubiquitination	ARKLKLESQVDLLQA HHHCHHHHHHHHHHH	46.04	29967540
1022	Phosphorylation	VDLLQAQSQQLQKHF HHHHHHHHHHHHHHH	23.94	-
1027	Ubiquitination	AQSQQLQKHFSSLEA HHHHHHHHHHHHHHH	56.03	29967540
1028	Ubiquitination	QSQQLQKHFSSLEAE HHHHHHHHHHHHHHH	18.17	16196087
1029	Ubiquitination	SQQLQKHFSSLEAEA HHHHHHHHHHHHHHH	7.36	21963094
1030	Phosphorylation	QQLQKHFSSLEAEAQ HHHHHHHHHHHHHHH	33.46	26714015
1030	Ubiquitination	QQLQKHFSSLEAEAQ HHHHHHHHHHHHHHH	33.46	29967540
1031	Phosphorylation	QLQKHFSSLEAEAQK HHHHHHHHHHHHHHH	29.32	25627689
1038	Ubiquitination	SLEAEAQKKQHLLRE HHHHHHHHHHHHHHH	62.54	29967540
1039	Ubiquitination	LEAEAQKKQHLLREV HHHHHHHHHHHHHHC	30.76	-
1041	Ubiquitination	AEAQKKQHLLREVTV HHHHHHHHHHHHCCC	35.39	29967540
1050	Ubiquitination	LREVTVEENNASPHF HHHCCCCCCCCCCCC	51.99	21963094
1054	Phosphorylation	TVEENNASPHFEPDL CCCCCCCCCCCCCCC	22.49	25159151
1057	Ubiquitination	ENNASPHFEPDLHIE CCCCCCCCCCCCCHH	19.37	21963094
1068	Ubiquitination	LHIEDLRKSLGTNQT CCHHHHHHHCCCCCH	58.28	29967540
1070	Ubiquitination	IEDLRKSLGTNQTKE HHHHHHHCCCCCHHH	12.60	21963094
1071	Ubiquitination	EDLRKSLGTNQTKEV HHHHHHCCCCCHHHH	29.70	29967540
1072	Phosphorylation	DLRKSLGTNQTKEVS HHHHHCCCCCHHHHH	29.46	29759185
1075	Phosphorylation	KSLGTNQTKEVSSSL HHCCCCCHHHHHHHH	31.10	29759185
1076	Ubiquitination	SLGTNQTKEVSSSLS HCCCCCHHHHHHHHH	46.48	21963094
1079	Ubiquitination	TNQTKEVSSSLSQSK CCCHHHHHHHHHCCC	18.46	21963094
1083	Phosphorylation	KEVSSSLSQSKEDLY HHHHHHHHCCCHHHH	34.06	25627689
1085	Phosphorylation	VSSSLSQSKEDLYLD HHHHHHCCCHHHHHH	34.34	25159151
1096	Ubiquitination	LYLDSLSSHNVWHLL HHHHCCHHCCHHHHH	25.11	21963094
1112	Phosphorylation	AEGVALRSAKEFLVQ HHCHHHHHHHHHHHH	44.54	29514088
1114	Ubiquitination	GVALRSAKEFLVQQT CHHHHHHHHHHHHHH	50.69	-
1121	Phosphorylation	KEFLVQQTRSMRRRQ HHHHHHHHHHHHHHH	13.97	29514088
1123	Phosphorylation	FLVQQTRSMRRRQTA HHHHHHHHHHHHHHH	21.74	29514088
1124	Ubiquitination	LVQQTRSMRRRQTAL HHHHHHHHHHHHHHH	3.30	21963094
1132	Methylation	RRRQTALKAAQQHWR HHHHHHHHHHHHHHH	38.93	-
1144	Ubiquitination	HWRHELASAQEVAKD HHHHHHHHHHHHHHC	43.01	21963094
1150	Ubiquitination	ASAQEVAKDPPGIKA HHHHHHHHCCCCHHH	75.77	21963094
1153	Ubiquitination	QEVAKDPPGIKALED HHHHHCCCCHHHHHH	68.24	21963094
1170	Ubiquitination	KNLEKETRHLDEMKS HHHHHHHHHHHHHHH	29.48	21963094
1176	Ubiquitination	TRHLDEMKSAMRKGH HHHHHHHHHHHHHHH	32.77	29967540
1179	Ubiquitination	LDEMKSAMRKGHNLL HHHHHHHHHHHHHHH	6.17	29967540
1181	Ubiquitination	EMKSAMRKGHNLLKK HHHHHHHHHHHHHHH	51.98	29967540
1184	Ubiquitination	SAMRKGHNLLKKKEE HHHHHHHHHHHHHHH	56.59	29967540
1198	Phosphorylation	EKLNQLESSLWEEAS HHHHHHHHHHHHHHC	39.05	27251275
1199	Phosphorylation	KLNQLESSLWEEASD HHHHHHHHHHHHHCC	28.29	27251275
1205	Phosphorylation	SSLWEEASDEGTLGG HHHHHHHCCCCCCCC	39.20	30108239
1209	Phosphorylation	EEASDEGTLGGSPTK HHHCCCCCCCCCCCC	21.85	30108239
1213	Phosphorylation	DEGTLGGSPTKKAVT CCCCCCCCCCCEEEE	27.83	30108239
1215	Phosphorylation	GTLGGSPTKKAVTFD CCCCCCCCCEEEEEE	47.04	30108239
1216	Ubiquitination	TLGGSPTKKAVTFDL CCCCCCCCEEEEEEC	41.96	29967540
1217	Ubiquitination	LGGSPTKKAVTFDLS CCCCCCCEEEEEECH	51.04	-
1219	Ubiquitination	GSPTKKAVTFDLSDM CCCCCEEEEEECHHH	8.23	29967540
1230	Phosphorylation	LSDMDSLSSESSESF CHHHHHCCCCCCCCC	35.69	30576142
1236	Phosphorylation	LSSESSESFSPPHRE CCCCCCCCCCCCCHH	32.73	30576142
1238	Ubiquitination	SESSESFSPPHREWW CCCCCCCCCCCHHHH	46.96	21963094
1241	Ubiquitination	SESFSPPHREWWRQQ CCCCCCCCHHHHHHH	43.61	22817900
1252	Phosphorylation	WRQQRIDSTPSLTSR HHHHCCCCCCCHHHH	39.59	20860994
1253	Phosphorylation	RQQRIDSTPSLTSRK HHHCCCCCCCHHHHH	17.10	-
1255	Phosphorylation	QRIDSTPSLTSRKIH HCCCCCCCHHHHHHH	44.35	30631047
1257	Phosphorylation	IDSTPSLTSRKIHGL CCCCCCHHHHHHHHH	30.72	23917254
1260	Ubiquitination	TPSLTSRKIHGLSHS CCCHHHHHHHHHHHH	38.53	-
1266	Ubiquitination	RKIHGLSHSLRQISS HHHHHHHHHHHHHHH	35.58	21963094
1267	Phosphorylation	KIHGLSHSLRQISSQ HHHHHHHHHHHHHHH	23.13	24719451
1269	Ubiquitination	HGLSHSLRQISSQLS HHHHHHHHHHHHHHH	34.50	22817900
1273	Phosphorylation	HSLRQISSQLSSVLS HHHHHHHHHHHHHHH	36.45	-
1284	Phosphorylation	SVLSILDSLNPQSPP HHHHHHHHCCCCCCC	26.97	-
1308	Phosphorylation	LPPRDPKSTPTPTYY CCCCCCCCCCCCCCH	45.03	20860994
1309	Phosphorylation	PPRDPKSTPTPTYYG CCCCCCCCCCCCCHH	36.99	25627689
1316	Ubiquitination	TPTPTYYGSLARFSA CCCCCCHHHHHHHHH	13.03	22817900
1318	Ubiquitination	TPTYYGSLARFSALS CCCCHHHHHHHHHHC	3.26	21963094
1333	Ubiquitination	SATPTSTQWAWDSGQ CCCCCCCCCCCCCCC	27.88	21963094
1336	Ubiquitination	PTSTQWAWDSGQGPR CCCCCCCCCCCCCCC	9.42	22817900
1344	Ubiquitination	DSGQGPRLPSSVAQT CCCCCCCCCHHHHHH	5.62	22817900
1346	Ubiquitination	GQGPRLPSSVAQTVD CCCCCCCHHHHHHHH	41.87	21963094
1353	Ubiquitination	SSVAQTVDDFLLEKW HHHHHHHHHHHHHHH	44.31	21963094
1354	Ubiquitination	SVAQTVDDFLLEKWR HHHHHHHHHHHHHHH	31.58	21963094
1356	Ubiquitination	AQTVDDFLLEKWRKY HHHHHHHHHHHHHHH	8.53	22817900
1357	Ubiquitination	QTVDDFLLEKWRKYF HHHHHHHHHHHHHHC	6.85	22817900
1359	Ubiquitination	VDDFLLEKWRKYFPS HHHHHHHHHHHHCCC	52.87	21963094
1362	Ubiquitination	FLLEKWRKYFPSGIP HHHHHHHHHCCCCCC	50.56	22817900
1372	Phosphorylation	PSGIPLLSNSPTPLE CCCCCCCCCCCCCHH	42.83	27251275
1374	Phosphorylation	GIPLLSNSPTPLESR CCCCCCCCCCCHHHH	27.12	28348404
1379	Ubiquitination	SNSPTPLESRLGYMS CCCCCCHHHHHCCCC	34.71	21963094
1382	Ubiquitination	PTPLESRLGYMSASE CCCHHHHHCCCCHHH	8.85	22817900
1384	Phosphorylation	PLESRLGYMSASEQL CHHHHHCCCCHHHHH	7.78	-
1386	Phosphorylation	ESRLGYMSASEQLRL HHHHCCCCHHHHHHH	21.84	23917254
1388	Phosphorylation	RLGYMSASEQLRLLQ HHCCCCHHHHHHHHH	20.69	23917254
1411	Ubiquitination	AGSTTFQGIIEANRR CCCCCHHHHHHHHHH	20.74	22817900
1413	Ubiquitination	STTFQGIIEANRRWL CCCHHHHHHHHHHHH	5.38	21963094
1431	Ubiquitination	KNDPRLPLFSSTPKP CCCCCCCCCCCCCCC	8.44	22817900
1432	Ubiquitination	NDPRLPLFSSTPKPK CCCCCCCCCCCCCCC	5.24	22817900
1433	Phosphorylation	DPRLPLFSSTPKPKA CCCCCCCCCCCCCCH	40.77	20860994
1433	Ubiquitination	DPRLPLFSSTPKPKA CCCCCCCCCCCCCCH	40.77	21963094
1434	Phosphorylation	PRLPLFSSTPKPKAT CCCCCCCCCCCCCHH	41.20	20860994
1434	Ubiquitination	PRLPLFSSTPKPKAT CCCCCCCCCCCCCHH	41.20	21963094
1435	Phosphorylation	RLPLFSSTPKPKATL CCCCCCCCCCCCHHH	33.85	28555341
1437	Ubiquitination	PLFSSTPKPKATLSL CCCCCCCCCCHHHHH	60.27	22817900
1439	Ubiquitination	FSSTPKPKATLSLLQ CCCCCCCCHHHHHHH	61.19	21963094
1441	Phosphorylation	STPKPKATLSLLQLG CCCCCCHHHHHHHCC	24.01	-
1443	Phosphorylation	PKPKATLSLLQLGLD CCCCHHHHHHHCCCC	23.76	10470851
1457	Ubiquitination	DEHNRVKVYRF---- CCCCCEEEEEC----	3.66	22817900
1459	Ubiquitination	HNRVKVYRF------ CCCEEEEEC------	33.51	21963094
1471	Ubiquitination	------------------ ------------------		16196087
1508	Ubiquitination	------------------------------------------------------- -------------------------------------------------------		16196087
1539	Ubiquitination	-------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------		21963094
1541	Ubiquitination	---------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------		16196087
1544	Ubiquitination	------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------		16196087
1564	Ubiquitination	--------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------		16196087
1570	Ubiquitination	--------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------		16196087
1573	Ubiquitination	------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------		16196087
1576	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------		21963094
1590	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------		16196087
1609	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1612	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1613	Ubiquitination	---------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1632	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1638	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1641	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1650	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1657	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1658	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1683	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1686	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1706	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1712	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1715	Ubiquitination	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1731	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1732	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1822	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1825	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1859	Ubiquitination	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1862	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1892	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1895	Ubiquitination	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1898	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1900	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1902	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1915	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1918	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1921	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1924	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1927	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1932	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1933	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1935	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1936	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1937	Ubiquitination	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1939	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1940	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1941	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1943	Ubiquitination	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1944	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1970	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1972	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1973	Ubiquitination	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1975	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1993	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
1995	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
1999	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
2001	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
2002	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
2004	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
2010	Ubiquitination	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
2011	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
2012	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
2013	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
2018	Ubiquitination	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
2019	Ubiquitination	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		22817900
2020	Ubiquitination	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094
2021	Ubiquitination	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21963094

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
186	S	Phosphorylation	Kinase	ATM	Q13315	Uniprot
186	S	Phosphorylation	Kinase	ATR	Q13535	Uniprot

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
186	S	Phosphorylation		18283122
Phosphorylation at Ser-186 is induced upon DNA-damage caused by treatment with IR irradiation, UV irradiation, hydroxyurea or amphidicolin.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CE164_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATR_HUMAN	ATR	physical	18283122
ATRIP_HUMAN	ATRIP	physical	18283122
CCD92_HUMAN	CCDC92	physical	22863007
TTBK2_HUMAN	TTBK2	physical	22863007
NPHP3_HUMAN	NPHP3	physical	22863007
NPHP4_HUMAN	NPHP4	physical	22863007
DVL3_HUMAN	DVL3	physical	22863007
MK14_HUMAN	MAPK14	physical	21988832
BTF3_HUMAN	BTF3	physical	26638075
CA131_HUMAN	C1orf131	physical	26638075
CAN1_HUMAN	CAPN1	physical	26638075
CEBPZ_HUMAN	CEBPZ	physical	26638075
CATB_HUMAN	CTSB	physical	26638075
DDX24_HUMAN	DDX24	physical	26638075
DDX47_HUMAN	DDX47	physical	26638075
DNJB6_HUMAN	DNAJB6	physical	26638075
EBP2_HUMAN	EBNA1BP2	physical	26638075
DHE4_HUMAN	GLUD2	physical	26638075
IDH3B_HUMAN	IDH3B	physical	26638075
LONM_HUMAN	LONP1	physical	26638075
MTPN_HUMAN	MTPN	physical	26638075
NMD3_HUMAN	NMD3	physical	26638075
NSUN2_HUMAN	NSUN2	physical	26638075
PDS5B_HUMAN	PDS5B	physical	26638075
PEF1_HUMAN	PEF1	physical	26638075
PPM1F_HUMAN	PPM1F	physical	26638075
RFOX2_HUMAN	RBFOX2	physical	26638075
RFC2_HUMAN	RFC2	physical	26638075
RPP38_HUMAN	RPP38	physical	26638075
SENP3_HUMAN	SENP3	physical	26638075
SRSF2_HUMAN	SRSF2	physical	26638075
SSRG_HUMAN	SSR3	physical	26638075
STX8_HUMAN	STX8	physical	26638075
WDR3_HUMAN	WDR3	physical	26638075
TYY1_HUMAN	YY1	physical	26638075
AATF_HUMAN	AATF	physical	26638075
NCBP3_HUMAN	C17orf85	physical	26638075
CSRP2_HUMAN	CSRP2	physical	26638075
ODB2_HUMAN	DBT	physical	26638075
DDX23_HUMAN	DDX23	physical	26638075
DDX56_HUMAN	DDX56	physical	26638075
ECH1_HUMAN	ECH1	physical	26638075
GPX1_HUMAN	GPX1	physical	26638075
NKRF_HUMAN	NKRF	physical	26638075
NOL11_HUMAN	NOL11	physical	26638075
NU205_HUMAN	NUP205	physical	26638075
NVL_HUMAN	NVL	physical	26638075
RRP5_HUMAN	PDCD11	physical	26638075
RPF2_HUMAN	RPF2	physical	26638075
SRS10_HUMAN	SRSF10	physical	26638075
SSRP1_HUMAN	SSRP1	physical	26638075
SP16H_HUMAN	SUPT16H	physical	26638075
TBL3_HUMAN	TBL3	physical	26638075
TOP2B_HUMAN	TOP2B	physical	26638075
TRA2B_HUMAN	TRA2B	physical	26638075
UBP36_HUMAN	USP36	physical	26638075
VN1R5_HUMAN	VN1R5	physical	26638075
ZN326_HUMAN	ZNF326	physical	26638075
NH2L1_HUMAN	NHP2L1	physical	26638075

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
614845	Nephronophthisis 15 (NPHP15)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CE164_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Cep164 is a mediator protein required for the maintenance of genomicstability through modulation of MDC1, RPA, and CHK1."; Sivasubramaniam S., Sun X., Pan Y.R., Wang S., Lee E.Y.; Genes Dev. 22:587-600(2008). Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION, INTERACTION WITHATM; ATR; ATRIP AND MDC1, SUBCELLULAR LOCATION, PHOSPHORYLATION ATSER-186, AND MUTAGENESIS OF SER-186.	18283122 [Abstract]

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