| UniProt ID | TOP2B_HUMAN | |
|---|---|---|
| UniProt AC | Q02880 | |
| Protein Name | DNA topoisomerase 2-beta | |
| Gene Name | TOP2B | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1626 | |
| Subcellular Localization | Cytoplasm. Nucleus, nucleolus. | |
| Protein Description | Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.. | |
| Protein Sequence | MAKSGGCGAGAGVGGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMFN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MAKSGGCGA ------CCCCCCCCC | 26.48 | - | |
| 3 | Acetylation | -----MAKSGGCGAG -----CCCCCCCCCC | 62.58 | - | |
| 3 (in isoform 2) | Ubiquitination | - | 62.58 | - | |
| 4 | Phosphorylation | ----MAKSGGCGAGA ----CCCCCCCCCCC | 47.69 | 22199227 | |
| 4 (in isoform 2) | Phosphorylation | - | 47.69 | 22199227 | |
| 29 (in isoform 2) | Ubiquitination | - | 41.79 | - | |
| 32 | Phosphorylation | LFDQNNAAKKEESET EECCCCCCHHHHHHH | 26.10 | 18491316 | |
| 33 | Sumoylation | FDQNNAAKKEESETA ECCCCCCHHHHHHHC | 59.30 | 28112733 | |
| 34 | Sumoylation | DQNNAAKKEESETAN CCCCCCHHHHHHHCC | 63.09 | - | |
| 34 | Sumoylation | DQNNAAKKEESETAN CCCCCCHHHHHHHCC | 63.09 | 25218447 | |
| 37 | Phosphorylation | NAAKKEESETANKND CCCHHHHHHHCCCCC | 41.14 | 18491316 | |
| 37 | Ubiquitination | NAAKKEESETANKND CCCHHHHHHHCCCCC | 41.14 | - | |
| 37 (in isoform 2) | Ubiquitination | - | 41.14 | 21890473 | |
| 40 | Phosphorylation | KKEESETANKNDSSK HHHHHHHCCCCCCCC | 22.43 | 18491316 | |
| 41 | Phosphorylation | KEESETANKNDSSKK HHHHHHCCCCCCCCC | 51.59 | 18491316 | |
| 42 | Ubiquitination | EESETANKNDSSKKL HHHHHCCCCCCCCCC | 60.72 | 21906983 | |
| 42 (in isoform 1) | Ubiquitination | - | 60.72 | 21890473 | |
| 45 | Phosphorylation | ETANKNDSSKKLSVE HHCCCCCCCCCCCHH | 54.15 | 18491316 | |
| 46 | Phosphorylation | TANKNDSSKKLSVER HCCCCCCCCCCCHHH | 36.35 | 18491316 | |
| 50 | Phosphorylation | NDSSKKLSVERVYQK CCCCCCCCHHHHHHH | 30.71 | 24719451 | |
| 55 | Phosphorylation | KLSVERVYQKKTQLE CCCHHHHHHHHHHHH | 22.34 | 29496963 | |
| 97 | Phosphorylation | GMNCREVTFVPGLYK CCCCEEEEECCHHHH | 17.73 | 21406692 | |
| 98 | Phosphorylation | MNCREVTFVPGLYKI CCCEEEEECCHHHHH | 8.24 | 20068231 | |
| 103 | Phosphorylation | VTFVPGLYKIFDEIL EEECCHHHHHHHHHH | 14.14 | 21406692 | |
| 112 | Ubiquitination | IFDEILVNAADNKQR HHHHHHHHCCCCCCC | 26.43 | - | |
| 112 (in isoform 2) | Ubiquitination | - | 26.43 | 21890473 | |
| 116 | Ubiquitination | ILVNAADNKQRDKNM HHHHCCCCCCCCCCC | 37.32 | - | |
| 116 (in isoform 2) | Ubiquitination | - | 37.32 | - | |
| 117 | Ubiquitination | LVNAADNKQRDKNMT HHHCCCCCCCCCCCE | 47.46 | - | |
| 117 (in isoform 1) | Ubiquitination | - | 47.46 | 21890473 | |
| 129 | Phosphorylation | NMTCIKVSIDPESNI CCEEEEEEECCCCCE | 19.10 | 20068231 | |
| 139 | Ubiquitination | PESNIISIWNNGKGI CCCCEEEEEECCCCC | 3.00 | - | |
| 139 (in isoform 2) | Ubiquitination | - | 3.00 | 21890473 | |
| 144 | Ubiquitination | ISIWNNGKGIPVVEH EEEEECCCCCCEEEE | 56.65 | 21906983 | |
| 144 (in isoform 1) | Ubiquitination | - | 56.65 | 21890473 | |
| 147 | Sumoylation | WNNGKGIPVVEHKVE EECCCCCCEEEECCE | 32.54 | - | |
| 147 | Ubiquitination | WNNGKGIPVVEHKVE EECCCCCCEEEECCE | 32.54 | - | |
| 147 (in isoform 2) | Ubiquitination | - | 32.54 | 21890473 | |
| 150 | Ubiquitination | GKGIPVVEHKVEKVY CCCCCEEEECCEEEE | 37.92 | - | |
| 150 (in isoform 2) | Ubiquitination | - | 37.92 | - | |
| 152 | Sumoylation | GIPVVEHKVEKVYVP CCCEEEECCEEEECC | 38.29 | - | |
| 152 | Phosphorylation | GIPVVEHKVEKVYVP CCCEEEECCEEEECC | 38.29 | 18452278 | |
| 152 | Ubiquitination | GIPVVEHKVEKVYVP CCCEEEECCEEEECC | 38.29 | 21906983 | |
| 152 (in isoform 1) | Ubiquitination | - | 38.29 | 21890473 | |
| 157 | Phosphorylation | EHKVEKVYVPALIFG EECCEEEECCHHHHH | 16.28 | 18452278 | |
| 172 | Phosphorylation | QLLTSSNYDDDEKKV HHHHCCCCCCCCCCC | 23.77 | - | |
| 172 | Sumoylation | QLLTSSNYDDDEKKV HHHHCCCCCCCCCCC | 23.77 | - | |
| 172 (in isoform 2) | Ubiquitination | - | 23.77 | - | |
| 173 (in isoform 2) | Ubiquitination | - | 62.22 | - | |
| 177 | Sumoylation | SNYDDDEKKVTGGRN CCCCCCCCCCCCCCC | 60.58 | 28112733 | |
| 177 | Ubiquitination | SNYDDDEKKVTGGRN CCCCCCCCCCCCCCC | 60.58 | - | |
| 178 | Sumoylation | NYDDDEKKVTGGRNG CCCCCCCCCCCCCCC | 42.87 | 28112733 | |
| 178 | Ubiquitination | NYDDDEKKVTGGRNG CCCCCCCCCCCCCCC | 42.87 | - | |
| 184 | Ubiquitination | KKVTGGRNGYGAKLC CCCCCCCCCHHHHHH | 51.84 | - | |
| 184 (in isoform 2) | Ubiquitination | - | 51.84 | - | |
| 189 | Ubiquitination | GRNGYGAKLCNIFST CCCCHHHHHHHHHCC | 49.57 | - | |
| 191 | Glutathionylation | NGYGAKLCNIFSTKF CCHHHHHHHHHCCCE | 3.46 | 22555962 | |
| 200 | Ubiquitination | IFSTKFTVETACKEY HHCCCEEHHHHHHHC | 7.47 | - | |
| 200 (in isoform 2) | Ubiquitination | - | 7.47 | - | |
| 205 | Acetylation | FTVETACKEYKHSFK EEHHHHHHHCHHHHH | 62.71 | 25953088 | |
| 207 | Ubiquitination | VETACKEYKHSFKQT HHHHHHHCHHHHHHH | 10.25 | - | |
| 212 | Ubiquitination | KEYKHSFKQTWMNNM HHCHHHHHHHHHHHH | 50.24 | - | |
| 216 | Ubiquitination | HSFKQTWMNNMMKTS HHHHHHHHHHHHHHC | 2.70 | - | |
| 216 (in isoform 2) | Ubiquitination | - | 2.70 | - | |
| 221 | Acetylation | TWMNNMMKTSEAKIK HHHHHHHHHCCCCCC | 37.82 | 25953088 | |
| 222 | Phosphorylation | WMNNMMKTSEAKIKH HHHHHHHHCCCCCCC | 17.57 | 29759185 | |
| 223 | Phosphorylation | MNNMMKTSEAKIKHF HHHHHHHCCCCCCCC | 30.00 | 29759185 | |
| 223 | Sumoylation | MNNMMKTSEAKIKHF HHHHHHHCCCCCCCC | 30.00 | - | |
| 223 | Ubiquitination | MNNMMKTSEAKIKHF HHHHHHHCCCCCCCC | 30.00 | - | |
| 223 (in isoform 2) | Ubiquitination | - | 30.00 | - | |
| 228 | Sumoylation | KTSEAKIKHFDGEDY HHCCCCCCCCCCCCC | 37.20 | - | |
| 228 | Acetylation | KTSEAKIKHFDGEDY HHCCCCCCCCCCCCC | 37.20 | 26051181 | |
| 228 | Sumoylation | KTSEAKIKHFDGEDY HHCCCCCCCCCCCCC | 37.20 | 28112733 | |
| 230 | Phosphorylation | SEAKIKHFDGEDYTC CCCCCCCCCCCCCEE | 12.55 | - | |
| 235 | Phosphorylation | KHFDGEDYTCITFQP CCCCCCCCEEEEECC | 10.14 | 17360941 | |
| 237 | Glutathionylation | FDGEDYTCITFQPDL CCCCCCEEEEECCCH | 1.94 | 22555962 | |
| 241 | Ubiquitination | DYTCITFQPDLSKFK CCEEEEECCCHHHHC | 23.19 | - | |
| 249 | Ubiquitination | PDLSKFKMEKLDKDI CCHHHHCHHHCCHHH | 6.55 | - | |
| 249 (in isoform 2) | Ubiquitination | - | 6.55 | 21890473 | |
| 254 | Ubiquitination | FKMEKLDKDIVALMT HCHHHCCHHHHHHHH | 60.84 | 21890473 | |
| 254 (in isoform 1) | Ubiquitination | - | 60.84 | 21890473 | |
| 261 | Phosphorylation | KDIVALMTRRAYDLA HHHHHHHHHHHHHHH | 20.18 | 26074081 | |
| 265 | Phosphorylation | ALMTRRAYDLAGSCR HHHHHHHHHHHHCCC | 15.07 | 26074081 | |
| 270 | Acetylation | RAYDLAGSCRGVKVM HHHHHHHCCCEEEEE | 8.60 | - | |
| 270 | Phosphorylation | RAYDLAGSCRGVKVM HHHHHHHCCCEEEEE | 8.60 | 26074081 | |
| 275 | Acetylation | AGSCRGVKVMFNGKK HHCCCEEEEEECCEE | 30.70 | 23749302 | |
| 277 | Ubiquitination | SCRGVKVMFNGKKLP CCCEEEEEECCEECC | 1.46 | - | |
| 277 (in isoform 2) | Ubiquitination | - | 1.46 | - | |
| 286 | Phosphorylation | NGKKLPVNGFRSYVD CCEECCCCCCHHHEE | 41.78 | - | |
| 290 | Phosphorylation | LPVNGFRSYVDLYVK CCCCCCHHHEEEEEE | 27.52 | 26074081 | |
| 291 | Phosphorylation | PVNGFRSYVDLYVKD CCCCCHHHEEEEEEC | 8.17 | 26074081 | |
| 292 | Ubiquitination | VNGFRSYVDLYVKDK CCCCHHHEEEEEECC | 4.27 | - | |
| 292 (in isoform 2) | Ubiquitination | - | 4.27 | - | |
| 294 | Ubiquitination | GFRSYVDLYVKDKLD CCHHHEEEEEECCCC | 3.65 | - | |
| 294 (in isoform 2) | Ubiquitination | - | 3.65 | 21890473 | |
| 299 | Sumoylation | VDLYVKDKLDETGVA EEEEEECCCCCCCHH | 52.71 | 28112733 | |
| 299 | Ubiquitination | VDLYVKDKLDETGVA EEEEEECCCCCCCHH | 52.71 | 21906983 | |
| 299 (in isoform 1) | Ubiquitination | - | 52.71 | 21890473 | |
| 303 | Ubiquitination | VKDKLDETGVALKVI EECCCCCCCHHHHHH | 36.30 | - | |
| 303 (in isoform 2) | Ubiquitination | - | 36.30 | 21890473 | |
| 308 | Acetylation | DETGVALKVIHELAN CCCCHHHHHHHHHHH | 29.43 | 26051181 | |
| 308 | Ubiquitination | DETGVALKVIHELAN CCCCHHHHHHHHHHH | 29.43 | 21906983 | |
| 308 (in isoform 1) | Ubiquitination | - | 29.43 | 21890473 | |
| 333 | Phosphorylation | EKGFQQISFVNSIAT HHCCCEEEEECCEEE | 20.85 | 20068231 | |
| 337 | Phosphorylation | QQISFVNSIATTKGG CEEEEECCEEECCCC | 14.32 | 26552605 | |
| 337 | Ubiquitination | QQISFVNSIATTKGG CEEEEECCEEECCCC | 14.32 | - | |
| 337 (in isoform 2) | Ubiquitination | - | 14.32 | 21890473 | |
| 340 | Phosphorylation | SFVNSIATTKGGRHV EEECCEEECCCCCCC | 27.63 | 26552605 | |
| 341 | Phosphorylation | FVNSIATTKGGRHVD EECCEEECCCCCCCH | 20.76 | 26552605 | |
| 342 | Ubiquitination | VNSIATTKGGRHVDY ECCEEECCCCCCCHH | 55.82 | 21890473 | |
| 342 (in isoform 1) | Ubiquitination | - | 55.82 | 21890473 | |
| 344 | Phosphorylation | SIATTKGGRHVDYVV CEEECCCCCCCHHHH | 20.34 | - | |
| 349 | Phosphorylation | KGGRHVDYVVDQVVG CCCCCCHHHHHHHHH | 10.98 | - | |
| 352 (in isoform 2) | Ubiquitination | - | 26.05 | - | |
| 360 | Acetylation | QVVGKLIEVVKKKNK HHHHHHHHHHHHCCC | 52.25 | 19608861 | |
| 360 (in isoform 2) | Ubiquitination | - | 52.25 | - | |
| 362 | Acetylation | VGKLIEVVKKKNKAG HHHHHHHHHHCCCCC | 4.95 | 19608861 | |
| 362 | Ubiquitination | VGKLIEVVKKKNKAG HHHHHHHHHHCCCCC | 4.95 | 19608861 | |
| 362 (in isoform 2) | Ubiquitination | - | 4.95 | 21890473 | |
| 363 | 2-Hydroxyisobutyrylation | GKLIEVVKKKNKAGV HHHHHHHHHCCCCCC | 64.31 | - | |
| 365 | Acetylation | LIEVVKKKNKAGVSV HHHHHHHCCCCCCCC | 58.94 | 19608861 | |
| 367 | Acetylation | EVVKKKNKAGVSVKP HHHHHCCCCCCCCCC | 56.23 | 19608861 | |
| 367 | Sumoylation | EVVKKKNKAGVSVKP HHHHHCCCCCCCCCC | 56.23 | 28112733 | |
| 367 | Ubiquitination | EVVKKKNKAGVSVKP HHHHHCCCCCCCCCC | 56.23 | 21906983 | |
| 367 (in isoform 1) | Ubiquitination | - | 56.23 | 21890473 | |
| 368 | Acetylation | VVKKKNKAGVSVKPF HHHHCCCCCCCCCCE | 32.77 | 19608861 | |
| 368 | Sumoylation | VVKKKNKAGVSVKPF HHHHCCCCCCCCCCE | 32.77 | 19608861 | |
| 368 | Ubiquitination | VVKKKNKAGVSVKPF HHHHCCCCCCCCCCE | 32.77 | 19608861 | |
| 368 (in isoform 2) | Ubiquitination | - | 32.77 | - | |
| 373 | Sumoylation | NKAGVSVKPFQVKNH CCCCCCCCCEEECCE | 32.38 | - | |
| 373 | Acetylation | NKAGVSVKPFQVKNH CCCCCCCCCEEECCE | 32.38 | 23749302 | |
| 373 | Sumoylation | NKAGVSVKPFQVKNH CCCCCCCCCEEECCE | 32.38 | 28112733 | |
| 373 | Ubiquitination | NKAGVSVKPFQVKNH CCCCCCCCCEEECCE | 32.38 | - | |
| 402 | Ubiquitination | DSQTKENMTLQPKSF CCCCCCCCCCCCCCC | 4.08 | - | |
| 402 (in isoform 2) | Ubiquitination | - | 4.08 | 21890473 | |
| 403 | Phosphorylation | SQTKENMTLQPKSFG CCCCCCCCCCCCCCC | 33.55 | 23403867 | |
| 407 | Methylation | ENMTLQPKSFGSKCQ CCCCCCCCCCCCCHH | 45.52 | - | |
| 407 | Ubiquitination | ENMTLQPKSFGSKCQ CCCCCCCCCCCCCHH | 45.52 | 21890473 | |
| 407 (in isoform 1) | Ubiquitination | - | 45.52 | 21890473 | |
| 407 (in isoform 2) | Ubiquitination | - | 45.52 | - | |
| 412 | Acetylation | QPKSFGSKCQLSEKF CCCCCCCCHHHCHHH | 26.78 | 26051181 | |
| 412 | Methylation | QPKSFGSKCQLSEKF CCCCCCCCHHHCHHH | 26.78 | 82993929 | |
| 412 | Ubiquitination | QPKSFGSKCQLSEKF CCCCCCCCHHHCHHH | 26.78 | - | |
| 413 | Ubiquitination | PKSFGSKCQLSEKFF CCCCCCCHHHCHHHH | 5.43 | - | |
| 413 (in isoform 2) | Ubiquitination | - | 5.43 | - | |
| 416 | Methylation | FGSKCQLSEKFFKAA CCCCHHHCHHHHHHH | 16.92 | - | |
| 418 | Acetylation | SKCQLSEKFFKAASN CCHHHCHHHHHHHHC | 53.37 | 25953088 | |
| 421 | Methylation | QLSEKFFKAASNCGI HHCHHHHHHHHCCCH | 46.29 | 115979721 | |
| 431 | Phosphorylation | SNCGIVESILNWVKF HCCCHHHHHHHHHHH | 22.83 | 21082442 | |
| 434 | Methylation | GIVESILNWVKFKAQ CHHHHHHHHHHHHHH | 39.56 | - | |
| 434 | Ubiquitination | GIVESILNWVKFKAQ CHHHHHHHHHHHHHH | 39.56 | - | |
| 434 (in isoform 2) | Ubiquitination | - | 39.56 | - | |
| 437 | Sumoylation | ESILNWVKFKAQTQL HHHHHHHHHHHHHHH | 32.53 | 28112733 | |
| 439 | Methylation | ILNWVKFKAQTQLNK HHHHHHHHHHHHHHH | 33.59 | 115979729 | |
| 439 | Sumoylation | ILNWVKFKAQTQLNK HHHHHHHHHHHHHHH | 33.59 | 28112733 | |
| 446 | Acetylation | KAQTQLNKKCSSVKY HHHHHHHHHCCCCCH | 64.84 | 25953088 | |
| 446 | Sumoylation | KAQTQLNKKCSSVKY HHHHHHHHHCCCCCH | 64.84 | 28112733 | |
| 447 | Acetylation | AQTQLNKKCSSVKYS HHHHHHHHCCCCCHH | 37.97 | - | |
| 448 | Phosphorylation | QTQLNKKCSSVKYSK HHHHHHHCCCCCHHH | 3.81 | - | |
| 452 | Acetylation | NKKCSSVKYSKIKGI HHHCCCCCHHHCCCC | 45.84 | 23749302 | |
| 453 | Phosphorylation | KKCSSVKYSKIKGIP HHCCCCCHHHCCCCC | 17.03 | 22461510 | |
| 456 | Sumoylation | SSVKYSKIKGIPKLD CCCCHHHCCCCCCCC | 3.98 | - | |
| 456 | Ubiquitination | SSVKYSKIKGIPKLD CCCCHHHCCCCCCCC | 3.98 | - | |
| 461 | Sumoylation | SKIKGIPKLDDANDA HHCCCCCCCCCCCCC | 63.73 | - | |
| 466 | Ubiquitination | IPKLDDANDAGGKHS CCCCCCCCCCCCCCC | 46.81 | - | |
| 466 (in isoform 2) | Ubiquitination | - | 46.81 | - | |
| 471 | Acetylation | DANDAGGKHSLECTL CCCCCCCCCCEEEEE | 29.15 | 26051181 | |
| 471 | Malonylation | DANDAGGKHSLECTL CCCCCCCCCCEEEEE | 29.15 | 26320211 | |
| 476 | Glutathionylation | GGKHSLECTLILTEG CCCCCEEEEEEEECC | 4.56 | 22555962 | |
| 482 | Ubiquitination | ECTLILTEGDSAKSL EEEEEEECCCCHHHE | 58.52 | - | |
| 482 (in isoform 2) | Ubiquitination | - | 58.52 | - | |
| 483 | Phosphorylation | CTLILTEGDSAKSLA EEEEEECCCCHHHEE | 29.01 | - | |
| 488 | Phosphorylation | TEGDSAKSLAVSGLG ECCCCHHHEEEEEEE | 22.68 | 21406692 | |
| 492 | Phosphorylation | SAKSLAVSGLGVIGR CHHHEEEEEEEEECC | 23.77 | 21406692 | |
| 505 | Sumoylation | GRDRYGVFPLRGKIL CCCCCCEECCCCCEE | 4.02 | - | |
| 505 | Ubiquitination | GRDRYGVFPLRGKIL CCCCCCEECCCCCEE | 4.02 | - | |
| 505 (in isoform 2) | Ubiquitination | - | 4.02 | 21890473 | |
| 510 | Sumoylation | GVFPLRGKILNVREA CEECCCCCEECHHHH | 37.27 | - | |
| 510 | Ubiquitination | GVFPLRGKILNVREA CEECCCCCEECHHHH | 37.27 | 21890473 | |
| 510 (in isoform 1) | Ubiquitination | - | 37.27 | 21890473 | |
| 515 | Ubiquitination | RGKILNVREASHKQI CCCEECHHHHHHHHH | 32.46 | - | |
| 515 (in isoform 2) | Ubiquitination | - | 32.46 | 21890473 | |
| 520 | Ubiquitination | NVREASHKQIMENAE CHHHHHHHHHHHHHH | 38.74 | 21890473 | |
| 520 (in isoform 1) | Ubiquitination | - | 38.74 | 21890473 | |
| 528 | Ubiquitination | QIMENAEINNIIKIV HHHHHHHHHHHHHHH | 4.43 | - | |
| 534 | Phosphorylation | EINNIIKIVGLQYKK HHHHHHHHHCEEECC | 1.78 | - | |
| 535 | Ubiquitination | INNIIKIVGLQYKKS HHHHHHHHCEEECCC | 5.49 | - | |
| 536 | Ubiquitination | NNIIKIVGLQYKKSY HHHHHHHCEEECCCC | 15.55 | - | |
| 536 (in isoform 2) | Ubiquitination | - | 15.55 | 21890473 | |
| 539 | Phosphorylation | IKIVGLQYKKSYDDA HHHHCEEECCCCCCH | 25.98 | 21406692 | |
| 540 | Malonylation | KIVGLQYKKSYDDAE HHHCEEECCCCCCHH | 23.45 | 26320211 | |
| 540 | Succinylation | KIVGLQYKKSYDDAE HHHCEEECCCCCCHH | 23.45 | 23954790 | |
| 540 | Ubiquitination | KIVGLQYKKSYDDAE HHHCEEECCCCCCHH | 23.45 | - | |
| 541 | Malonylation | IVGLQYKKSYDDAES HHCEEECCCCCCHHH | 49.68 | 26320211 | |
| 541 | Ubiquitination | IVGLQYKKSYDDAES HHCEEECCCCCCHHH | 49.68 | 21890473 | |
| 541 (in isoform 1) | Ubiquitination | - | 49.68 | 21890473 | |
| 545 | Ubiquitination | QYKKSYDDAESLKTL EECCCCCCHHHHHHC | 43.96 | - | |
| 545 (in isoform 2) | Ubiquitination | - | 43.96 | 21890473 | |
| 550 | Acetylation | YDDAESLKTLRYGKI CCCHHHHHHCCCCEE | 55.59 | 25953088 | |
| 550 | Ubiquitination | YDDAESLKTLRYGKI CCCHHHHHHCCCCEE | 55.59 | 21890473 | |
| 550 (in isoform 1) | Ubiquitination | - | 55.59 | 21890473 | |
| 551 | Phosphorylation | DDAESLKTLRYGKIM CCHHHHHHCCCCEEE | 23.04 | 23403867 | |
| 551 | Ubiquitination | DDAESLKTLRYGKIM CCHHHHHHCCCCEEE | 23.04 | - | |
| 551 (in isoform 2) | Ubiquitination | - | 23.04 | 21890473 | |
| 556 | Ubiquitination | LKTLRYGKIMIMTDQ HHHCCCCEEEEECCC | 21.84 | 21890473 | |
| 556 (in isoform 1) | Ubiquitination | - | 21.84 | 21890473 | |
| 584 | Phosphorylation | FIHHNWPSLLKHGFL HHHCCHHHHHHCCHH | 37.64 | 24719451 | |
| 587 | "N6,N6-dimethyllysine" | HNWPSLLKHGFLEEF CCHHHHHHCCHHHHC | 47.15 | - | |
| 587 | Methylation | HNWPSLLKHGFLEEF CCHHHHHHCCHHHHC | 47.15 | - | |
| 595 | Sumoylation | HGFLEEFITPIVKAS CCHHHHCHHHHHHHC | 5.18 | - | |
| 595 | Ubiquitination | HGFLEEFITPIVKAS CCHHHHCHHHHHHHC | 5.18 | - | |
| 595 (in isoform 2) | Ubiquitination | - | 5.18 | 21890473 | |
| 600 | Sumoylation | EFITPIVKASKNKQE HCHHHHHHHCCCCCC | 47.89 | - | |
| 600 | Sumoylation | EFITPIVKASKNKQE HCHHHHHHHCCCCCC | 47.89 | 28112733 | |
| 600 | Ubiquitination | EFITPIVKASKNKQE HCHHHHHHHCCCCCC | 47.89 | 21906983 | |
| 600 (in isoform 1) | Ubiquitination | - | 47.89 | 21890473 | |
| 600 (in isoform 2) | Ubiquitination | - | 47.89 | 21890473 | |
| 605 | Acetylation | IVKASKNKQELSFYS HHHHCCCCCCCCCEE | 49.22 | 26051181 | |
| 605 | Sumoylation | IVKASKNKQELSFYS HHHHCCCCCCCCCEE | 49.22 | 28112733 | |
| 605 | Ubiquitination | IVKASKNKQELSFYS HHHHCCCCCCCCCEE | 49.22 | 21906983 | |
| 605 (in isoform 1) | Ubiquitination | - | 49.22 | 21890473 | |
| 615 | Ubiquitination | LSFYSIPEFDEWKKH CCCEECCCHHHHHHH | 65.15 | - | |
| 615 (in isoform 2) | Ubiquitination | - | 65.15 | 21890473 | |
| 616 (in isoform 2) | Ubiquitination | - | 9.65 | - | |
| 620 | Ubiquitination | IPEFDEWKKHIENQK CCCHHHHHHHHHHCC | 32.21 | 21906983 | |
| 620 (in isoform 1) | Ubiquitination | - | 32.21 | 21890473 | |
| 621 | Acetylation | PEFDEWKKHIENQKA CCHHHHHHHHHHCCH | 51.38 | 7927305 | |
| 622 | Ubiquitination | EFDEWKKHIENQKAW CHHHHHHHHHHCCHH | 28.94 | - | |
| 622 (in isoform 2) | Ubiquitination | - | 28.94 | 21890473 | |
| 627 | Ubiquitination | KKHIENQKAWKIKYY HHHHHHCCHHEEEEE | 68.73 | 21906983 | |
| 627 (in isoform 1) | Ubiquitination | - | 68.73 | 21890473 | |
| 630 | Ubiquitination | IENQKAWKIKYYKGL HHHCCHHEEEEECCC | 33.89 | - | |
| 630 (in isoform 2) | Ubiquitination | - | 33.89 | 21890473 | |
| 634 | Phosphorylation | KAWKIKYYKGLGTST CHHEEEEECCCCCCC | 8.12 | 17081983 | |
| 635 | Phosphorylation | AWKIKYYKGLGTSTA HHEEEEECCCCCCCH | 44.57 | 17081983 | |
| 635 | Sumoylation | AWKIKYYKGLGTSTA HHEEEEECCCCCCCH | 44.57 | 28112733 | |
| 635 | Ubiquitination | AWKIKYYKGLGTSTA HHEEEEECCCCCCCH | 44.57 | 21906983 | |
| 635 (in isoform 1) | Ubiquitination | - | 44.57 | 21890473 | |
| 638 | Sumoylation | IKYYKGLGTSTAKEA EEEECCCCCCCHHHH | 26.70 | - | |
| 638 | Ubiquitination | IKYYKGLGTSTAKEA EEEECCCCCCCHHHH | 26.70 | - | |
| 638 (in isoform 2) | Ubiquitination | - | 26.70 | 21890473 | |
| 639 | Phosphorylation | KYYKGLGTSTAKEAK EEECCCCCCCHHHHH | 28.13 | 22817900 | |
| 640 | Phosphorylation | YYKGLGTSTAKEAKE EECCCCCCCHHHHHH | 25.27 | 22817900 | |
| 641 | Sumoylation | YKGLGTSTAKEAKEY ECCCCCCCHHHHHHH | 41.40 | - | |
| 641 | Ubiquitination | YKGLGTSTAKEAKEY ECCCCCCCHHHHHHH | 41.40 | - | |
| 641 (in isoform 2) | Ubiquitination | - | 41.40 | 21890473 | |
| 643 | Sumoylation | GLGTSTAKEAKEYFA CCCCCCHHHHHHHHH | 59.29 | - | |
| 643 | Sumoylation | GLGTSTAKEAKEYFA CCCCCCHHHHHHHHH | 59.29 | 28112733 | |
| 643 | Ubiquitination | GLGTSTAKEAKEYFA CCCCCCHHHHHHHHH | 59.29 | 21906983 | |
| 643 (in isoform 1) | Ubiquitination | - | 59.29 | 21890473 | |
| 646 | Sumoylation | TSTAKEAKEYFADME CCCHHHHHHHHHHHH | 54.78 | - | |
| 646 | Sumoylation | TSTAKEAKEYFADME CCCHHHHHHHHHHHH | 54.78 | 28112733 | |
| 646 | Ubiquitination | TSTAKEAKEYFADME CCCHHHHHHHHHHHH | 54.78 | 21906983 | |
| 646 (in isoform 1) | Ubiquitination | - | 54.78 | 21890473 | |
| 671 | Ubiquitination | PEDDAAITLAFSKKK CCCCHHHHHEEECCC | 13.80 | - | |
| 671 (in isoform 2) | Ubiquitination | - | 13.80 | 21890473 | |
| 672 (in isoform 2) | Ubiquitination | - | 3.56 | - | |
| 676 | Sumoylation | AITLAFSKKKIDDRK HHHHEEECCCCCCHH | 52.19 | 28112733 | |
| 676 | Ubiquitination | AITLAFSKKKIDDRK HHHHEEECCCCCCHH | 52.19 | 21906983 | |
| 676 (in isoform 1) | Ubiquitination | - | 52.19 | 21890473 | |
| 678 | Sumoylation | TLAFSKKKIDDRKEW HHEEECCCCCCHHHH | 55.92 | - | |
| 678 | Ubiquitination | TLAFSKKKIDDRKEW HHEEECCCCCCHHHH | 55.92 | - | |
| 678 (in isoform 2) | Ubiquitination | - | 55.92 | 21890473 | |
| 683 | Sumoylation | KKKIDDRKEWLTNFM CCCCCCHHHHHHHHH | 61.30 | - | |
| 683 | Ubiquitination | KKKIDDRKEWLTNFM CCCCCCHHHHHHHHH | 61.30 | 21890473 | |
| 683 (in isoform 1) | Ubiquitination | - | 61.30 | 21890473 | |
| 688 | Methylation | DRKEWLTNFMEDRRQ CHHHHHHHHHHHHHH | 31.90 | - | |
| 693 | Methylation | LTNFMEDRRQRRLHG HHHHHHHHHHHHHHC | 24.27 | - | |
| 707 | Phosphorylation | GLPEQFLYGTATKHL CCCHHHHHHHHCCCC | 17.45 | - | |
| 707 | Ubiquitination | GLPEQFLYGTATKHL CCCHHHHHHHHCCCC | 17.45 | - | |
| 707 (in isoform 2) | Ubiquitination | - | 17.45 | 21890473 | |
| 712 | Sumoylation | FLYGTATKHLTYNDF HHHHHHCCCCCHHHC | 33.87 | 28112733 | |
| 712 | Ubiquitination | FLYGTATKHLTYNDF HHHHHHCCCCCHHHC | 33.87 | 21906983 | |
| 712 (in isoform 1) | Ubiquitination | - | 33.87 | 21890473 | |
| 717 | Ubiquitination | ATKHLTYNDFINKEL HCCCCCHHHCCCCEE | 32.26 | - | |
| 725 | Phosphorylation | DFINKELILFSNSDN HCCCCEEEEEECCCC | 3.71 | - | |
| 728 | Phosphorylation | NKELILFSNSDNERS CCEEEEEECCCCCCC | 31.79 | 20068231 | |
| 730 | Phosphorylation | ELILFSNSDNERSIP EEEEEECCCCCCCCC | 40.38 | 20068231 | |
| 735 | Phosphorylation | SNSDNERSIPSLVDG ECCCCCCCCCHHCCC | 32.45 | - | |
| 738 | Phosphorylation | DNERSIPSLVDGFKP CCCCCCCHHCCCCCC | 39.08 | - | |
| 739 | Ubiquitination | NERSIPSLVDGFKPG CCCCCCHHCCCCCCC | 3.23 | - | |
| 739 (in isoform 2) | Ubiquitination | - | 3.23 | 21890473 | |
| 744 | Ubiquitination | PSLVDGFKPGQRKVL CHHCCCCCCCCCEEE | 54.49 | 21890473 | |
| 744 (in isoform 1) | Ubiquitination | - | 54.49 | 21890473 | |
| 744 (in isoform 2) | Ubiquitination | - | 54.49 | - | |
| 749 | Ubiquitination | GFKPGQRKVLFTCFK CCCCCCCEEEEEEEE | 35.09 | - | |
| 751 | Ubiquitination | KPGQRKVLFTCFKRN CCCCCEEEEEEEECC | 3.10 | - | |
| 751 (in isoform 2) | Ubiquitination | - | 3.10 | - | |
| 829 | Phosphorylation | ASPRYIFTMLSTLAR CCHHHHHHHHHHHHH | 13.98 | 30243723 | |
| 832 | Phosphorylation | RYIFTMLSTLARLLF HHHHHHHHHHHHHHC | 15.56 | 30243723 | |
| 833 | Phosphorylation | YIFTMLSTLARLLFP HHHHHHHHHHHHHCH | 22.07 | 30243723 | |
| 848 | Ubiquitination | AVDDNLLKFLYDDNQ HCCCCHHHHHCCCCC | 36.17 | - | |
| 851 | Phosphorylation | DNLLKFLYDDNQRVE CCHHHHHCCCCCCCC | 25.12 | 25147952 | |
| 884 | Ubiquitination | IGTGWACKLPNYDAR CCCCCCCCCCCCCHH | 60.27 | - | |
| 888 | Phosphorylation | WACKLPNYDAREIVN CCCCCCCCCHHHHHH | 14.72 | - | |
| 912 (in isoform 2) | Ubiquitination | - | 57.35 | - | |
| 913 | Phosphorylation | PHPMLPNYKNFKGTI CCCCCCCCCCCCHHH | 12.84 | - | |
| 928 | Phosphorylation | QELGQNQYAVSGEIF HHHHCCCEEEECEEE | 19.27 | - | |
| 965 | Ubiquitination | EQVLEPMLNGTDKTP HHHCHHHHCCCCCCC | 8.60 | - | |
| 965 (in isoform 2) | Ubiquitination | - | 8.60 | 21890473 | |
| 970 | Ubiquitination | PMLNGTDKTPALISD HHHCCCCCCCCHHHC | 57.13 | 21906983 | |
| 970 (in isoform 1) | Ubiquitination | - | 57.13 | 21890473 | |
| 971 | Phosphorylation | MLNGTDKTPALISDY HHCCCCCCCCHHHCH | 19.32 | 20068231 | |
| 973 | Phosphorylation | NGTDKTPALISDYKE CCCCCCCCHHHCHHH | 23.82 | 20068231 | |
| 974 | Acetylation | GTDKTPALISDYKEY CCCCCCCHHHCHHHH | 3.97 | - | |
| 974 | Ubiquitination | GTDKTPALISDYKEY CCCCCCCHHHCHHHH | 3.97 | - | |
| 974 (in isoform 2) | Ubiquitination | - | 3.97 | 21890473 | |
| 976 | Phosphorylation | DKTPALISDYKEYHT CCCCCHHHCHHHHCC | 35.42 | 20068231 | |
| 978 | Phosphorylation | TPALISDYKEYHTDT CCCHHHCHHHHCCCC | 10.03 | 20068231 | |
| 979 | Acetylation | PALISDYKEYHTDTT CCHHHCHHHHCCCCE | 57.71 | 25825284 | |
| 979 | Ubiquitination | PALISDYKEYHTDTT CCHHHCHHHHCCCCE | 57.71 | 21906983 | |
| 979 (in isoform 1) | Ubiquitination | - | 57.71 | 21890473 | |
| 983 | Ubiquitination | SDYKEYHTDTTVKFV HCHHHHCCCCEEEEE | 33.85 | - | |
| 983 (in isoform 2) | Ubiquitination | - | 33.85 | 21890473 | |
| 987 | Acetylation | EYHTDTTVKFVVKMT HHCCCCEEEEEEECC | 5.00 | 19608861 | |
| 987 | Ubiquitination | EYHTDTTVKFVVKMT HHCCCCEEEEEEECC | 5.00 | 19608861 | |
| 987 (in isoform 2) | Ubiquitination | - | 5.00 | - | |
| 988 | Ubiquitination | YHTDTTVKFVVKMTE HCCCCEEEEEEECCH | 30.28 | 21890473 | |
| 988 (in isoform 1) | Ubiquitination | - | 30.28 | 21890473 | |
| 992 | Acetylation | TTVKFVVKMTEEKLA CEEEEEEECCHHHHH | 34.50 | - | |
| 992 | Malonylation | TTVKFVVKMTEEKLA CEEEEEEECCHHHHH | 34.50 | 30639696 | |
| 997 | Acetylation | VVKMTEEKLAQAEAA EEECCHHHHHHHHHC | 42.78 | 25953088 | |
| 1003 | Acetylation | EKLAQAEAAGLHKVF HHHHHHHHCCHHHHC | 15.17 | - | |
| 1003 | Ubiquitination | EKLAQAEAAGLHKVF HHHHHHHHCCHHHHC | 15.17 | - | |
| 1003 (in isoform 2) | Ubiquitination | - | 15.17 | 21890473 | |
| 1008 | Acetylation | AEAAGLHKVFKLQTT HHHCCHHHHCCEEEE | 55.18 | 25825284 | |
| 1008 | Ubiquitination | AEAAGLHKVFKLQTT HHHCCHHHHCCEEEE | 55.18 | 21890473 | |
| 1008 (in isoform 1) | Ubiquitination | - | 55.18 | 21890473 | |
| 1027 | Sumoylation | SMVLFDHMGCLKKYE CEEEECCCCHHHHCH | 4.34 | - | |
| 1027 | Ubiquitination | SMVLFDHMGCLKKYE CEEEECCCCHHHHCH | 4.34 | - | |
| 1032 | Sumoylation | DHMGCLKKYETVQDI CCCCHHHHCHHHHHH | 35.06 | - | |
| 1049 | Phosphorylation | EFFDLRLSYYGLRKE HHHHHHHHHHHCCHH | 15.18 | 20860994 | |
| 1063 | Ubiquitination | EWLVGMLGAESTKLN HHHHHHHCCCCHHCH | 20.57 | - | |
| 1063 (in isoform 2) | Ubiquitination | - | 20.57 | 21890473 | |
| 1066 | Phosphorylation | VGMLGAESTKLNNQA HHHHCCCCHHCHHHH | 30.24 | 27732954 | |
| 1067 | Phosphorylation | GMLGAESTKLNNQAR HHHCCCCHHCHHHHH | 30.93 | 27732954 | |
| 1068 | Ubiquitination | MLGAESTKLNNQARF HHCCCCHHCHHHHHH | 59.50 | 21906983 | |
| 1068 (in isoform 1) | Ubiquitination | - | 59.50 | 21890473 | |
| 1074 | Ubiquitination | TKLNNQARFILEKIQ HHCHHHHHHHHHHHC | 14.90 | - | |
| 1074 (in isoform 2) | Ubiquitination | - | 14.90 | - | |
| 1078 | Ubiquitination | NQARFILEKIQGKIT HHHHHHHHHHCCCEE | 43.21 | - | |
| 1078 (in isoform 2) | Ubiquitination | - | 43.21 | - | |
| 1079 | 2-Hydroxyisobutyrylation | QARFILEKIQGKITI HHHHHHHHHCCCEEE | 36.56 | - | |
| 1079 | Ubiquitination | QARFILEKIQGKITI HHHHHHHHHCCCEEE | 36.56 | - | |
| 1086 (in isoform 2) | Ubiquitination | - | 5.14 | - | |
| 1087 | Ubiquitination | IQGKITIENRSKKDL HCCCEEECCCCHHHH | 37.63 | - | |
| 1090 | Phosphorylation | KITIENRSKKDLIQM CEEECCCCHHHHHHH | 56.49 | - | |
| 1092 | Sumoylation | TIENRSKKDLIQMLV EECCCCHHHHHHHHH | 60.04 | 28112733 | |
| 1104 | Ubiquitination | MLVQRGYESDPVKAW HHHHCCCCCCHHHHH | 52.03 | - | |
| 1104 (in isoform 2) | Ubiquitination | - | 52.03 | - | |
| 1124 | Phosphorylation | KAAEEDETQNQHDDS HHHHCHHHHCCCCCC | 45.18 | 26074081 | |
| 1126 | Phosphorylation | AEEDETQNQHDDSSS HHCHHHHCCCCCCCC | 48.88 | 18452278 | |
| 1127 | Phosphorylation | EEDETQNQHDDSSSD HCHHHHCCCCCCCCC | 31.41 | 18452278 | |
| 1128 | Phosphorylation | EDETQNQHDDSSSDS CHHHHCCCCCCCCCC | 48.68 | 18452278 | |
| 1130 | Phosphorylation | ETQNQHDDSSSDSGT HHHCCCCCCCCCCCC | 48.58 | 18452278 | |
| 1131 | Phosphorylation | TQNQHDDSSSDSGTP HHCCCCCCCCCCCCC | 37.49 | 26074081 | |
| 1132 | Phosphorylation | QNQHDDSSSDSGTPS HCCCCCCCCCCCCCC | 45.20 | 26074081 | |
| 1133 | Phosphorylation | NQHDDSSSDSGTPSG CCCCCCCCCCCCCCC | 39.48 | 26074081 | |
| 1134 | Phosphorylation | QHDDSSSDSGTPSGP CCCCCCCCCCCCCCC | 53.70 | 18452278 | |
| 1135 | Phosphorylation | HDDSSSDSGTPSGPD CCCCCCCCCCCCCCC | 46.65 | 26074081 | |
| 1137 | Phosphorylation | DSSSDSGTPSGPDFN CCCCCCCCCCCCCHH | 20.45 | 26074081 | |
| 1139 | Phosphorylation | SSDSGTPSGPDFNYI CCCCCCCCCCCHHHH | 63.90 | 30576142 | |
| 1145 | Phosphorylation | PSGPDFNYILNMSLW CCCCCHHHHHHHHHH | 13.53 | 21406692 | |
| 1150 | Phosphorylation | FNYILNMSLWSLTKE HHHHHHHHHHHHCHH | 26.13 | 21406692 | |
| 1153 | Phosphorylation | ILNMSLWSLTKEKVE HHHHHHHHHCHHHHH | 31.30 | 21406692 | |
| 1155 | Phosphorylation | NMSLWSLTKEKVEEL HHHHHHHCHHHHHHH | 31.48 | 21406692 | |
| 1158 | Acetylation | LWSLTKEKVEELIKQ HHHHCHHHHHHHHHH | 57.41 | 25953088 | |
| 1159 | Ubiquitination | WSLTKEKVEELIKQR HHHCHHHHHHHHHHH | 7.88 | - | |
| 1180 | Phosphorylation | VNDLKRKSPSDLWKE HHHHCCCCHHHHHHH | 33.40 | 27794612 | |
| 1182 | Phosphorylation | DLKRKSPSDLWKEDL HHCCCCHHHHHHHHH | 53.04 | 26546556 | |
| 1207 | Phosphorylation | ESQEREDVLAGMSGK CHHHHHHHHHHCCCC | 3.19 | 20068231 | |
| 1209 | Ubiquitination | QEREDVLAGMSGKAI HHHHHHHHHCCCCCC | 16.10 | - | |
| 1209 (in isoform 2) | Ubiquitination | - | 16.10 | 21890473 | |
| 1212 | Phosphorylation | EDVLAGMSGKAIKGK HHHHHHCCCCCCCCC | 35.90 | 25159151 | |
| 1214 | Acetylation | VLAGMSGKAIKGKVG HHHHCCCCCCCCCCC | 39.36 | 23236377 | |
| 1214 | Sumoylation | VLAGMSGKAIKGKVG HHHHCCCCCCCCCCC | 39.36 | 28112733 | |
| 1214 | Ubiquitination | VLAGMSGKAIKGKVG HHHHCCCCCCCCCCC | 39.36 | 21906983 | |
| 1214 (in isoform 1) | Ubiquitination | - | 39.36 | 21890473 | |
| 1217 | Sumoylation | GMSGKAIKGKVGKPK HCCCCCCCCCCCCCC | 58.50 | 28112733 | |
| 1222 | Sumoylation | AIKGKVGKPKVKKLQ CCCCCCCCCCCCEEE | 44.65 | - | |
| 1222 | Ubiquitination | AIKGKVGKPKVKKLQ CCCCCCCCCCCCEEE | 44.65 | - | |
| 1222 (in isoform 2) | Ubiquitination | - | 44.65 | 21890473 | |
| 1226 | Sumoylation | KVGKPKVKKLQLEET CCCCCCCCEEECEEC | 54.62 | 28112733 | |
| 1227 | Sumoylation | VGKPKVKKLQLEETM CCCCCCCEEECEECC | 44.44 | - | |
| 1227 | Sumoylation | VGKPKVKKLQLEETM CCCCCCCEEECEECC | 44.44 | 28112733 | |
| 1227 | Ubiquitination | VGKPKVKKLQLEETM CCCCCCCEEECEECC | 44.44 | 21906983 | |
| 1227 (in isoform 1) | Ubiquitination | - | 44.44 | 21890473 | |
| 1228 | Phosphorylation | GKPKVKKLQLEETMP CCCCCCEEECEECCC | 6.10 | - | |
| 1231 | Phosphorylation | KVKKLQLEETMPSPY CCCEEECEECCCCCC | 38.16 | 19691289 | |
| 1233 | Phosphorylation | KKLQLEETMPSPYGR CEEECEECCCCCCHH | 25.63 | 29255136 | |
| 1236 | Phosphorylation | QLEETMPSPYGRRII ECEECCCCCCHHCCH | 21.67 | 23401153 | |
| 1238 | Phosphorylation | EETMPSPYGRRIIPE EECCCCCCHHCCHHH | 27.83 | 21712546 | |
| 1242 | Phosphorylation | PSPYGRRIIPEITAM CCCCHHCCHHHHHEE | 6.24 | - | |
| 1245 | Sumoylation | YGRRIIPEITAMKAD CHHCCHHHHHEECCH | 42.43 | - | |
| 1245 | Ubiquitination | YGRRIIPEITAMKAD CHHCCHHHHHEECCH | 42.43 | - | |
| 1245 (in isoform 2) | Ubiquitination | - | 42.43 | 21890473 | |
| 1247 | Phosphorylation | RRIIPEITAMKADAS HCCHHHHHEECCHHH | 21.02 | 27251275 | |
| 1250 | Sumoylation | IPEITAMKADASKKL HHHHHEECCHHHHHH | 40.42 | - | |
| 1250 | Sumoylation | IPEITAMKADASKKL HHHHHEECCHHHHHH | 40.42 | 28112733 | |
| 1250 | Ubiquitination | IPEITAMKADASKKL HHHHHEECCHHHHHH | 40.42 | 21906983 | |
| 1250 (in isoform 1) | Ubiquitination | - | 40.42 | 21890473 | |
| 1255 | Acetylation | AMKADASKKLLKKKK EECCHHHHHHHHHCC | 49.51 | 19826747 | |
| 1257 | Ubiquitination | KADASKKLLKKKKGD CCHHHHHHHHHCCCC | 11.02 | - | |
| 1257 (in isoform 2) | Ubiquitination | - | 11.02 | 21890473 | |
| 1259 | Acetylation | DASKKLLKKKKGDLD HHHHHHHHHCCCCCC | 73.34 | 19826759 | |
| 1260 | Acetylation | ASKKLLKKKKGDLDT HHHHHHHHCCCCCCC | 60.74 | 19826771 | |
| 1262 | Phosphorylation | KKLLKKKKGDLDTAA HHHHHHCCCCCCCCE | 67.54 | - | |
| 1262 | Sumoylation | KKLLKKKKGDLDTAA HHHHHHCCCCCCCCE | 67.54 | 28112733 | |
| 1262 | Ubiquitination | KKLLKKKKGDLDTAA HHHHHHCCCCCCCCE | 67.54 | 21906983 | |
| 1262 (in isoform 1) | Ubiquitination | - | 67.54 | 21890473 | |
| 1266 | Sumoylation | KKKKGDLDTAAVKVE HHCCCCCCCCEEEEE | 38.75 | - | |
| 1267 | Phosphorylation | KKKGDLDTAAVKVEF HCCCCCCCCEEEEEE | 24.66 | 23312004 | |
| 1271 | Sumoylation | DLDTAAVKVEFDEEF CCCCCEEEEEECHHH | 31.18 | - | |
| 1271 | Sumoylation | DLDTAAVKVEFDEEF CCCCCEEEEEECHHH | 31.18 | 28112733 | |
| 1274 | Phosphorylation | TAAVKVEFDEEFSGA CCEEEEEECHHHCCC | 18.77 | - | |
| 1279 | Phosphorylation | VEFDEEFSGAPVEGA EEECHHHCCCCCCCC | 37.01 | 24732914 | |
| 1287 | Phosphorylation | GAPVEGAGEEALTPS CCCCCCCCCCCCCCC | 44.10 | 20068231 | |
| 1292 | Phosphorylation | GAGEEALTPSVPINK CCCCCCCCCCCCCCC | 22.14 | 30266825 | |
| 1294 | Phosphorylation | GEEALTPSVPINKGP CCCCCCCCCCCCCCC | 34.98 | 30266825 | |
| 1294 | Ubiquitination | GEEALTPSVPINKGP CCCCCCCCCCCCCCC | 34.98 | - | |
| 1294 (in isoform 2) | Ubiquitination | - | 34.98 | 21890473 | |
| 1297 | Ubiquitination | ALTPSVPINKGPKPK CCCCCCCCCCCCCCC | 8.57 | - | |
| 1297 (in isoform 2) | Ubiquitination | - | 8.57 | 21890473 | |
| 1299 | Ubiquitination | TPSVPINKGPKPKRE CCCCCCCCCCCCCCC | 76.84 | 21906983 | |
| 1299 (in isoform 1) | Ubiquitination | - | 76.84 | 21890473 | |
| 1302 | Ubiquitination | VPINKGPKPKREKKE CCCCCCCCCCCCCCC | 72.36 | 21906983 | |
| 1302 (in isoform 1) | Ubiquitination | - | 72.36 | 21890473 | |
| 1307 | Acetylation | GPKPKREKKEPGTRV CCCCCCCCCCCCCCC | 67.48 | 12435243 | |
| 1312 | Phosphorylation | REKKEPGTRVRKTPT CCCCCCCCCCCCCCC | 36.38 | - | |
| 1317 | Phosphorylation | PGTRVRKTPTSSGKP CCCCCCCCCCCCCCC | 22.64 | 26055452 | |
| 1318 | Acetylation | GTRVRKTPTSSGKPS CCCCCCCCCCCCCCC | 33.06 | - | |
| 1318 | Ubiquitination | GTRVRKTPTSSGKPS CCCCCCCCCCCCCCC | 33.06 | - | |
| 1318 (in isoform 2) | Ubiquitination | - | 33.06 | 21890473 | |
| 1319 | Phosphorylation | TRVRKTPTSSGKPSA CCCCCCCCCCCCCCC | 40.53 | 30576142 | |
| 1320 | Phosphorylation | RVRKTPTSSGKPSAK CCCCCCCCCCCCCCC | 37.99 | 30576142 | |
| 1321 | Phosphorylation | VRKTPTSSGKPSAKK CCCCCCCCCCCCCCC | 54.00 | 29759185 | |
| 1323 | Acetylation | KTPTSSGKPSAKKVK CCCCCCCCCCCCCHH | 37.43 | 23749302 | |
| 1323 | Sumoylation | KTPTSSGKPSAKKVK CCCCCCCCCCCCCHH | 37.43 | 28112733 | |
| 1323 | Ubiquitination | KTPTSSGKPSAKKVK CCCCCCCCCCCCCHH | 37.43 | 21906983 | |
| 1323 (in isoform 1) | Ubiquitination | - | 37.43 | 21890473 | |
| 1325 | Phosphorylation | PTSSGKPSAKKVKKR CCCCCCCCCCCHHHC | 57.09 | 26055452 | |
| 1327 | Acetylation | SSGKPSAKKVKKRNP CCCCCCCCCHHHCCC | 63.54 | 19852659 | |
| 1327 | Sumoylation | SSGKPSAKKVKKRNP CCCCCCCCCHHHCCC | 63.54 | 28112733 | |
| 1328 | Acetylation | SGKPSAKKVKKRNPW CCCCCCCCHHHCCCC | 60.03 | 19852671 | |
| 1331 | Phosphorylation | PSAKKVKKRNPWSDD CCCCCHHHCCCCCCC | 61.47 | 19691289 | |
| 1335 | Phosphorylation | KVKKRNPWSDDESKS CHHHCCCCCCCCCCC | 20.24 | 20068231 | |
| 1336 | Phosphorylation | VKKRNPWSDDESKSE HHHCCCCCCCCCCCH | 36.12 | 23927012 | |
| 1337 | Phosphorylation | KKRNPWSDDESKSES HHCCCCCCCCCCCHH | 60.88 | 19691289 | |
| 1339 | Phosphorylation | RNPWSDDESKSESDL CCCCCCCCCCCHHHH | 66.12 | 20068231 | |
| 1340 | Phosphorylation | NPWSDDESKSESDLE CCCCCCCCCCHHHHH | 48.77 | 26503892 | |
| 1342 | Phosphorylation | WSDDESKSESDLEET CCCCCCCCHHHHHHC | 52.17 | 29255136 | |
| 1344 | Phosphorylation | DDESKSESDLEETEP CCCCCCHHHHHHCCC | 55.37 | 29255136 | |
| 1349 | Phosphorylation | SESDLEETEPVVIPR CHHHHHHCCCEEECH | 35.89 | 26503892 | |
| 1353 | Phosphorylation | LEETEPVVIPRDSLL HHHCCCEEECHHHHH | 7.94 | - | |
| 1357 | Methylation | EPVVIPRDSLLRRAA CCEEECHHHHHHHHH | 37.98 | - | |
| 1358 | Phosphorylation | PVVIPRDSLLRRAAA CEEECHHHHHHHHHH | 30.50 | 21406692 | |
| 1362 | Methylation | PRDSLLRRAAAERPK CHHHHHHHHHHHCCC | 28.66 | 115386163 | |
| 1365 | Phosphorylation | SLLRRAAAERPKYTF HHHHHHHHHCCCEEE | 16.61 | 18669648 | |
| 1366 | Phosphorylation | LLRRAAAERPKYTFD HHHHHHHHCCCEEEC | 65.86 | 17081983 | |
| 1367 | Methylation | LRRAAAERPKYTFDF HHHHHHHCCCEEECC | 28.43 | 115386171 | |
| 1370 | Phosphorylation | AAAERPKYTFDFSEE HHHHCCCEEECCCCC | 18.47 | 30278072 | |
| 1371 | Phosphorylation | AAERPKYTFDFSEEE HHHCCCEEECCCCCC | 23.89 | 30278072 | |
| 1375 | Phosphorylation | PKYTFDFSEEEDDDA CCEEECCCCCCCCCC | 46.04 | 26503892 | |
| 1395 | Phosphorylation | DNNDLEELKVKASPI CCCCHHHHEEEEECC | 5.88 | 19691289 | |
| 1398 | Phosphorylation | DLEELKVKASPITND CHHHHEEEEECCCCC | 41.37 | 18452278 | |
| 1398 | Sumoylation | DLEELKVKASPITND CHHHHEEEEECCCCC | 41.37 | 28112733 | |
| 1400 | Phosphorylation | EELKVKASPITNDGE HHHEEEEECCCCCCC | 15.89 | 29255136 | |
| 1403 | Phosphorylation | KVKASPITNDGEDEF EEEEECCCCCCCCCC | 30.55 | 29255136 | |
| 1408 | Phosphorylation | PITNDGEDEFVPSDG CCCCCCCCCCCCCCC | 61.23 | 20068231 | |
| 1413 | Phosphorylation | GEDEFVPSDGLDKDE CCCCCCCCCCCCCCC | 38.72 | 29255136 | |
| 1416 | Phosphorylation | EFVPSDGLDKDEYTF CCCCCCCCCCCCEEC | 9.93 | 18669648 | |
| 1417 | Phosphorylation | FVPSDGLDKDEYTFS CCCCCCCCCCCEECC | 62.99 | 20068231 | |
| 1419 | Phosphorylation | PSDGLDKDEYTFSPG CCCCCCCCCEECCCC | 54.52 | 19651622 | |
| 1421 | Phosphorylation | DGLDKDEYTFSPGKS CCCCCCCEECCCCCC | 24.18 | 23927012 | |
| 1422 | Phosphorylation | GLDKDEYTFSPGKSK CCCCCCEECCCCCCC | 18.65 | 25159151 | |
| 1424 | Phosphorylation | DKDEYTFSPGKSKAT CCCCEECCCCCCCCC | 25.58 | 29255136 | |
| 1426 | Phosphorylation | DEYTFSPGKSKATPE CCEECCCCCCCCCCC | 45.75 | - | |
| 1427 | Acetylation | EYTFSPGKSKATPEK CEECCCCCCCCCCCC | 52.76 | 25953088 | |
| 1428 | Phosphorylation | YTFSPGKSKATPEKS EECCCCCCCCCCCCC | 33.18 | 23927012 | |
| 1429 | Acetylation | TFSPGKSKATPEKSL ECCCCCCCCCCCCCC | 60.82 | - | |
| 1431 | Phosphorylation | SPGKSKATPEKSLHD CCCCCCCCCCCCCCC | 35.40 | 26074081 | |
| 1434 | Acetylation | KSKATPEKSLHDKKS CCCCCCCCCCCCCCC | 60.57 | 23749302 | |
| 1435 | Phosphorylation | SKATPEKSLHDKKSQ CCCCCCCCCCCCCCC | 29.31 | 26074081 | |
| 1435 | Sumoylation | SKATPEKSLHDKKSQ CCCCCCCCCCCCCCC | 29.31 | - | |
| 1435 | Ubiquitination | SKATPEKSLHDKKSQ CCCCCCCCCCCCCCC | 29.31 | - | |
| 1435 (in isoform 2) | Ubiquitination | - | 29.31 | - | |
| 1436 | Phosphorylation | KATPEKSLHDKKSQD CCCCCCCCCCCCCCC | 10.04 | 19651622 | |
| 1440 | Sumoylation | EKSLHDKKSQDFGNL CCCCCCCCCCCCCCC | 60.45 | - | |
| 1440 | Sumoylation | EKSLHDKKSQDFGNL CCCCCCCCCCCCCCC | 60.45 | 28112733 | |
| 1440 | Ubiquitination | EKSLHDKKSQDFGNL CCCCCCCCCCCCCCC | 60.45 | - | |
| 1441 | Phosphorylation | KSLHDKKSQDFGNLF CCCCCCCCCCCCCCC | 40.50 | 25159151 | |
| 1444 | Phosphorylation | HDKKSQDFGNLFSFP CCCCCCCCCCCCCCC | 5.61 | - | |
| 1447 | Phosphorylation | KSQDFGNLFSFPSYS CCCCCCCCCCCCCCC | 3.78 | 20068231 | |
| 1448 | Phosphorylation | SQDFGNLFSFPSYSQ CCCCCCCCCCCCCCC | 9.08 | 18452278 | |
| 1449 | Phosphorylation | QDFGNLFSFPSYSQK CCCCCCCCCCCCCCC | 39.14 | 17525332 | |
| 1451 | Sumoylation | FGNLFSFPSYSQKSE CCCCCCCCCCCCCCC | 31.03 | - | |
| 1451 | Ubiquitination | FGNLFSFPSYSQKSE CCCCCCCCCCCCCCC | 31.03 | - | |
| 1452 | Phosphorylation | GNLFSFPSYSQKSED CCCCCCCCCCCCCCC | 35.09 | 25159151 | |
| 1453 | Phosphorylation | NLFSFPSYSQKSEDD CCCCCCCCCCCCCCC | 18.50 | 21712546 | |
| 1454 | Phosphorylation | LFSFPSYSQKSEDDS CCCCCCCCCCCCCCC | 35.15 | 17525332 | |
| 1456 | Sumoylation | SFPSYSQKSEDDSAK CCCCCCCCCCCCCCC | 50.28 | - | |
| 1456 | Phosphorylation | SFPSYSQKSEDDSAK CCCCCCCCCCCCCCC | 50.28 | 18452278 | |
| 1456 | Sumoylation | SFPSYSQKSEDDSAK CCCCCCCCCCCCCCC | 50.28 | 28112733 | |
| 1457 | Phosphorylation | FPSYSQKSEDDSAKF CCCCCCCCCCCCCCC | 38.32 | 25159151 | |
| 1461 | Phosphorylation | SQKSEDDSAKFDSNE CCCCCCCCCCCCCCC | 45.76 | 25159151 | |
| 1466 | Phosphorylation | DDSAKFDSNEEDSAS CCCCCCCCCCCHHHC | 49.64 | 29255136 | |
| 1468 | Phosphorylation | SAKFDSNEEDSASVF CCCCCCCCCHHHCCC | 68.11 | 18452278 | |
| 1471 | Phosphorylation | FDSNEEDSASVFSPS CCCCCCHHHCCCCCC | 26.23 | 29255136 | |
| 1473 | Phosphorylation | SNEEDSASVFSPSFG CCCCHHHCCCCCCCC | 27.87 | 29255136 | |
| 1476 | Phosphorylation | EDSASVFSPSFGLKQ CHHHCCCCCCCCCCC | 19.92 | 30266825 | |
| 1477 | Ubiquitination | DSASVFSPSFGLKQT HHHCCCCCCCCCCCC | 23.39 | - | |
| 1478 | Phosphorylation | SASVFSPSFGLKQTD HHCCCCCCCCCCCCC | 30.65 | 30266825 | |
| 1481 | Acetylation | VFSPSFGLKQTDKVP CCCCCCCCCCCCCCC | 3.33 | - | |
| 1486 | Acetylation | FGLKQTDKVPSKTVA CCCCCCCCCCCCCEE | 60.47 | 23749302 | |
| 1489 | Phosphorylation | KQTDKVPSKTVAAKK CCCCCCCCCCEEECC | 43.90 | 26270265 | |
| 1490 | Acetylation | QTDKVPSKTVAAKKG CCCCCCCCCEEECCC | 40.73 | 25953088 | |
| 1490 | Sumoylation | QTDKVPSKTVAAKKG CCCCCCCCCEEECCC | 40.73 | 28112733 | |
| 1491 | Phosphorylation | TDKVPSKTVAAKKGK CCCCCCCCEEECCCC | 21.51 | 26270265 | |
| 1496 | Phosphorylation | SKTVAAKKGKPSSDT CCCEEECCCCCCCCC | 68.39 | 19691289 | |
| 1500 | Phosphorylation | AAKKGKPSSDTVPKP EECCCCCCCCCCCCC | 44.31 | 19691289 | |
| 1501 | Phosphorylation | AKKGKPSSDTVPKPK ECCCCCCCCCCCCCC | 45.91 | 19691289 | |
| 1503 | Phosphorylation | KGKPSSDTVPKPKRA CCCCCCCCCCCCCCC | 40.43 | 19691289 | |
| 1517 | Phosphorylation | APKQKKVVEAVNSDS CCCCCHHECCCCCCC | 5.55 | 19664994 | |
| 1519 | Phosphorylation | KQKKVVEAVNSDSDS CCCHHECCCCCCCCC | 8.32 | 19691289 | |
| 1521 | Phosphorylation | KKVVEAVNSDSDSEF CHHECCCCCCCCCCC | 47.34 | 20068231 | |
| 1522 | Phosphorylation | KVVEAVNSDSDSEFG HHECCCCCCCCCCCC | 31.71 | 19664994 | |
| 1524 | Phosphorylation | VEAVNSDSDSEFGIP ECCCCCCCCCCCCCC | 42.74 | 29255136 | |
| 1526 | Phosphorylation | AVNSDSDSEFGIPKK CCCCCCCCCCCCCCC | 38.48 | 29255136 | |
| 1534 | Phosphorylation | EFGIPKKTTTPKGKG CCCCCCCCCCCCCCC | 41.87 | 26425664 | |
| 1535 | Phosphorylation | FGIPKKTTTPKGKGR CCCCCCCCCCCCCCC | 50.40 | 23312004 | |
| 1536 | Phosphorylation | GIPKKTTTPKGKGRG CCCCCCCCCCCCCCC | 28.38 | 26425664 | |
| 1545 | Phosphorylation | KGKGRGAKKRKASGS CCCCCCCCCCCCCCC | 56.80 | 20068231 | |
| 1547 | Phosphorylation | KGRGAKKRKASGSEN CCCCCCCCCCCCCCC | 38.78 | 20068231 | |
| 1550 | Phosphorylation | GAKKRKASGSENEGD CCCCCCCCCCCCCCC | 45.98 | 29255136 | |
| 1552 | Phosphorylation | KKRKASGSENEGDYN CCCCCCCCCCCCCCC | 34.45 | 29255136 | |
| 1553 | Phosphorylation | KRKASGSENEGDYNP CCCCCCCCCCCCCCC | 63.93 | 17081983 | |
| 1558 | Phosphorylation | GSENEGDYNPGRKTS CCCCCCCCCCCCCCC | 33.83 | 23927012 | |
| 1564 | Phosphorylation | DYNPGRKTSKTTSKK CCCCCCCCCCCCCCC | 33.81 | 26074081 | |
| 1565 | Phosphorylation | YNPGRKTSKTTSKKP CCCCCCCCCCCCCCC | 30.92 | 26074081 | |
| 1567 | Phosphorylation | PGRKTSKTTSKKPKK CCCCCCCCCCCCCCC | 35.75 | 26074081 | |
| 1568 | Phosphorylation | GRKTSKTTSKKPKKT CCCCCCCCCCCCCCC | 42.14 | 26074081 | |
| 1569 | Phosphorylation | RKTSKTTSKKPKKTS CCCCCCCCCCCCCCC | 43.86 | 26074081 | |
| 1569 | Ubiquitination | RKTSKTTSKKPKKTS CCCCCCCCCCCCCCC | 43.86 | - | |
| 1569 (in isoform 2) | Ubiquitination | - | 43.86 | 21890473 | |
| 1570 | Phosphorylation | KTSKTTSKKPKKTSF CCCCCCCCCCCCCCC | 71.63 | 20068231 | |
| 1571 | Phosphorylation | TSKTTSKKPKKTSFD CCCCCCCCCCCCCCC | 62.93 | 17081983 | |
| 1574 | Ubiquitination | TTSKKPKKTSFDQDS CCCCCCCCCCCCCCC | 58.91 | 2190698 | |
| 1574 (in isoform 1) | Ubiquitination | - | 58.91 | 21890473 | |
| 1575 | Phosphorylation | TSKKPKKTSFDQDSD CCCCCCCCCCCCCCC | 40.53 | 29255136 | |
| 1576 | Phosphorylation | SKKPKKTSFDQDSDV CCCCCCCCCCCCCCC | 35.39 | 29255136 | |
| 1581 | Phosphorylation | KTSFDQDSDVDIFPS CCCCCCCCCCCCCCC | 33.62 | 29255136 | |
| 1583 | Phosphorylation | SFDQDSDVDIFPSDF CCCCCCCCCCCCCCC | 7.62 | - | |
| 1587 | Phosphorylation | DSDVDIFPSDFPTEP CCCCCCCCCCCCCCC | 33.07 | 18669648 | |
| 1588 | Phosphorylation | SDVDIFPSDFPTEPP CCCCCCCCCCCCCCC | 40.93 | 29255136 | |
| 1591 | Phosphorylation | DIFPSDFPTEPPSLP CCCCCCCCCCCCCCC | 40.62 | 17081983 | |
| 1592 | Phosphorylation | IFPSDFPTEPPSLPR CCCCCCCCCCCCCCC | 62.20 | 23927012 | |
| 1595 | Phosphorylation | SDFPTEPPSLPRTGR CCCCCCCCCCCCCCC | 42.12 | - | |
| 1596 | Phosphorylation | DFPTEPPSLPRTGRA CCCCCCCCCCCCCCC | 62.82 | 23927012 | |
| 1600 | Phosphorylation | EPPSLPRTGRARKEV CCCCCCCCCCCCHHE | 29.13 | 22199227 | |
| 1604 | Phosphorylation | LPRTGRARKEVKYFA CCCCCCCCHHEEEEC | 34.02 | 18669648 | |
| 1608 | Phosphorylation | GRARKEVKYFAESDE CCCCHHEEEECCCCC | 35.42 | 17081983 | |
| 1609 | Phosphorylation | RARKEVKYFAESDEE CCCHHEEEECCCCCC | 17.13 | 28176443 | |
| 1613 | Phosphorylation | EVKYFAESDEEEDDV HEEEECCCCCCCCCC | 47.06 | 30266825 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TOP2B_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TOP2B_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HDAC1_HUMAN | HDAC1 | physical | 11136718 | |
| U520_HUMAN | SNRNP200 | physical | 22939629 | |
| XPC_HUMAN | XPC | physical | 22939629 | |
| UBC9_HUMAN | UBE2I | physical | 10862613 | |
| GLYR1_HUMAN | GLYR1 | physical | 26344197 | |
| DPOE3_HUMAN | POLE3 | physical | 26344197 | |
| SP16H_HUMAN | SUPT16H | physical | 26344197 | |
| TOP1_HUMAN | TOP1 | physical | 26344197 |
loading...
| Acetylation | |
| Reference | PubMed |
| "Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-365; LYS-367; LYS-373 ANDLYS-992, AND MASS SPECTROMETRY. | |
| Phosphorylation | |
| Reference | PubMed |
| "Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1236; THR-1292;SER-1342; SER-1344; SER-1375; SER-1400; THR-1403; SER-1413; SER-1424;SER-1461; SER-1466; SER-1473; SER-1476; SER-1522; SER-1524; THR-1575AND SER-1581, AND MASS SPECTROMETRY. | |
| "Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1413; SER-1466;SER-1522; SER-1524 AND SER-1526, AND MASS SPECTROMETRY. | |
| "A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1236; SER-1336;SER-1340; SER-1342; SER-1344; SER-1375; SER-1400; SER-1413; TYR-1421;SER-1424; SER-1466; SER-1522; SER-1524; SER-1526; SER-1550; SER-1552;SER-1576; SER-1581; THR-1592; SER-1596; TYR-1609 AND SER-1613, ANDMASS SPECTROMETRY. | |
| "Phosphorylation analysis of primary human T lymphocytes usingsequential IMAC and titanium oxide enrichment."; Carrascal M., Ovelleiro D., Casas V., Gay M., Abian J.; J. Proteome Res. 7:5167-5176(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1400, AND MASSSPECTROMETRY. | |
| "Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1400; SER-1413;SER-1424; THR-1575 AND SER-1581, AND MASS SPECTROMETRY. | |
| "ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1454, AND MASSSPECTROMETRY. | |
| "Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1236, AND MASSSPECTROMETRY. | |
| "Toward a global characterization of the phosphoproteome in prostatecancer cells: identification of phosphoproteins in the LNCaP cellline."; Giorgianni F., Zhao Y., Desiderio D.M., Beranova-Giorgianni S.; Electrophoresis 28:2027-2034(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1522 AND SER-1524, ANDMASS SPECTROMETRY. | |
| "Phosphoproteome analysis of the human mitotic spindle."; Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.; Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1471; SER-1522 ANDSER-1524, AND MASS SPECTROMETRY. | |
| "Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-639; SER-640; SER-1336;SER-1340; SER-1342; SER-1344; SER-1400; SER-1413; SER-1522; SER-1524AND SER-1550, AND MASS SPECTROMETRY. | |
| "Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1466 AND SER-1522, ANDMASS SPECTROMETRY. | |
