dbPTM

DESP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DESP_HUMAN
UniProt AC	P15924
Protein Name	Desmoplakin
Gene Name	DSP
Organism	Homo sapiens (Human).
Sequence Length	2871
Subcellular Localization	Cell junction, desmosome . Cytoplasm, cytoskeleton . Cell membrane . Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network (PubMed:12802069). Localizes
Protein Description	Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes..
Protein Sequence	MSCNGGSHPRINTLGRMIRAESGPDLRYEVTSGGGGTSRMYYSRRGVITDQNSDGYCQTGTMSRHQNQNTIQELLQNCSDCLMRAELIVQPELKYGDGIQLTRSRELDECFAQANDQMEILDSLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLGWMRQQRAEMDMVAWGVDLASVEQHINSHRGIHNSIGDYRWQLDKIKADLREKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWHYCMIDIEKIRAMTIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQSQFTDAQKHYQTLVIQLPGYPQHQTVTTTEITHHGTCQDVNHNKVIETNRENDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELKSVQNDSQAIAEVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAILQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHSQTSQQYPLYDLDLGKFGEKVTQLTDRWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYSYSYSFSSSSIGH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSCNGGSHP ------CCCCCCCCC	27.82	25849741
7	Phosphorylation	-MSCNGGSHPRINTL -CCCCCCCCCCCCCH	31.55	25849741
13	Phosphorylation	GSHPRINTLGRMIRA CCCCCCCCHHHHHHC	28.37	27273156
19	Methylation	NTLGRMIRAESGPDL CCHHHHHHCCCCCCC	23.98	-
22	Phosphorylation	GRMIRAESGPDLRYE HHHHHCCCCCCCEEE	55.42	19664994
22 (in isoform 2)	Phosphorylation	-	55.42	-
27	Methylation	AESGPDLRYEVTSGG CCCCCCCEEEEECCC	32.71	-
27	Phosphorylation	AESGPDLRYEVTSGG CCCCCCCEEEEECCC	32.71	17016520
28	Phosphorylation	ESGPDLRYEVTSGGG CCCCCCEEEEECCCC	23.27	21945579
28 (in isoform 2)	Phosphorylation	-	23.27	-
31	Phosphorylation	PDLRYEVTSGGGGTS CCCEEEEECCCCCCC	15.09	21945579
32	Phosphorylation	DLRYEVTSGGGGTSR CCEEEEECCCCCCCE	40.39	21945579
37	Phosphorylation	VTSGGGGTSRMYYSR EECCCCCCCEEEEEC	19.21	21945579
38	Phosphorylation	TSGGGGTSRMYYSRR ECCCCCCCEEEEECC	20.51	21945579
41	Phosphorylation	GGGTSRMYYSRRGVI CCCCCEEEEECCCEE	9.36	27259358
42	Phosphorylation	GGTSRMYYSRRGVIT CCCCEEEEECCCEEC	6.07	-
43	Phosphorylation	GTSRMYYSRRGVITD CCCEEEEECCCEECC	9.67	26356563
45	Methylation	SRMYYSRRGVITDQN CEEEEECCCEECCCC	37.48	-
49	Phosphorylation	YSRRGVITDQNSDGY EECCCEECCCCCCCC	29.17	21945579
53	Phosphorylation	GVITDQNSDGYCQTG CEECCCCCCCCCCCC	27.12	21945579
55	Phosphorylation	ITDQNSDGYCQTGTM ECCCCCCCCCCCCCC	25.57	17016520
56	Phosphorylation	TDQNSDGYCQTGTMS CCCCCCCCCCCCCCC	6.08	21945579
56 (in isoform 2)	Phosphorylation	-	6.08	-
59	Phosphorylation	NSDGYCQTGTMSRHQ CCCCCCCCCCCCCCC	30.93	21945579
61	Phosphorylation	DGYCQTGTMSRHQNQ CCCCCCCCCCCCCCH	18.50	21945579
63	Phosphorylation	YCQTGTMSRHQNQNT CCCCCCCCCCCCHHH	26.84	21945579
79	Phosphorylation	QELLQNCSDCLMRAE HHHHHHHHHHHHHHH	38.62	20873877
94	Acetylation	LIVQPELKYGDGIQL HEECCCCCCCCCCCC	45.59	26051181
94	Ubiquitination	LIVQPELKYGDGIQL HEECCCCCCCCCCCC	45.59	21890473
94 (in isoform 1)	Ubiquitination	-	45.59	21890473
94 (in isoform 2)	Ubiquitination	-	45.59	21890473
95	Phosphorylation	IVQPELKYGDGIQLT EECCCCCCCCCCCCC	32.83	27273156
102	Phosphorylation	YGDGIQLTRSRELDE CCCCCCCCCCHHHHH	15.38	28152594
123	Phosphorylation	DQMEILDSLIREMRQ HHHHHHHHHHHHHHH	23.42	24719451
131	Sulfoxidation	LIREMRQMGQPCDAY HHHHHHHCCCCCHHH	3.67	28465586
140	Acetylation	QPCDAYQKRLLQLQE CCCHHHHHHHHHHHH	32.13	26051181
140	Ubiquitination	QPCDAYQKRLLQLQE CCCHHHHHHHHHHHH	32.13	-
154	Acetylation	EQMRALYKAISVPRV HHHHHHHHHCCCCCC	39.84	26051181
154	Ubiquitination	EQMRALYKAISVPRV HHHHHHHHHCCCCCC	39.84	21890473
154 (in isoform 1)	Ubiquitination	-	39.84	21890473
154 (in isoform 2)	Ubiquitination	-	39.84	21890473
157	Phosphorylation	RALYKAISVPRVRRA HHHHHHCCCCCCCCC	30.81	23403867
157 (in isoform 2)	Phosphorylation	-	30.81	-
165	Phosphorylation	VPRVRRASSKGGGGY CCCCCCCCCCCCCCC	30.67	25463755
165 (in isoform 2)	Phosphorylation	-	30.67	-
166	Phosphorylation	PRVRRASSKGGGGYT CCCCCCCCCCCCCCC	34.04	27273156
166 (in isoform 2)	Phosphorylation	-	34.04	-
167	Ubiquitination	RVRRASSKGGGGYTC CCCCCCCCCCCCCCC	60.11	-
172	Phosphorylation	SSKGGGGYTCQSGSG CCCCCCCCCCCCCCC	13.97	25463755
172 (in isoform 2)	Phosphorylation	-	13.97	-
173	Phosphorylation	SKGGGGYTCQSGSGW CCCCCCCCCCCCCCH	13.82	21945579
173 (in isoform 2)	Phosphorylation	-	13.82	-
176	Phosphorylation	GGGYTCQSGSGWDEF CCCCCCCCCCCHHHH	36.75	19664994
176 (in isoform 2)	Phosphorylation	-	36.75	-
178	Phosphorylation	GYTCQSGSGWDEFTK CCCCCCCCCHHHHHH	41.79	21945579
178 (in isoform 2)	Phosphorylation	-	41.79	-
184	Phosphorylation	GSGWDEFTKHVTSEC CCCHHHHHHHHHHHH	20.42	21945579
188	Phosphorylation	DEFTKHVTSECLGWM HHHHHHHHHHHHHHH	20.66	20873877
189	Phosphorylation	EFTKHVTSECLGWMR HHHHHHHHHHHHHHH	25.81	20873877
213	Phosphorylation	AWGVDLASVEQHINS HHCCCHHHHHHHHHC	33.22	20068231
213 (in isoform 2)	Phosphorylation	-	33.22	-
220	Phosphorylation	SVEQHINSHRGIHNS HHHHHHHCCCCCCCC	17.60	20068231
227	Phosphorylation	SHRGIHNSIGDYRWQ CCCCCCCCCCCHHHH	17.49	20873877
231	Phosphorylation	IHNSIGDYRWQLDKI CCCCCCCHHHHHHHH	14.45	-
245	Ubiquitination	IKADLREKSAIYQLE HCHHHHHHHHHHHHH	38.46	21906983
245 (in isoform 1)	Ubiquitination	-	38.46	21890473
245 (in isoform 2)	Ubiquitination	-	38.46	21890473
246	Phosphorylation	KADLREKSAIYQLEE CHHHHHHHHHHHHHH	18.36	28102081
246 (in isoform 2)	Phosphorylation	-	18.36	-
249	Phosphorylation	LREKSAIYQLEEEYE HHHHHHHHHHHHHHH	13.53	21082442
255	Phosphorylation	IYQLEEEYENLLKAS HHHHHHHHHHHHHHH	17.25	26356563
299	Phosphorylation	EELLYDWSDKNTNIA HHHHHCCCCCCCCHH	35.49	22817900
301	Acetylation	LLYDWSDKNTNIAQK HHHCCCCCCCCHHHH	61.22	7461957
308	Acetylation	KNTNIAQKQEAFSIR CCCCHHHHHHHHHHH	40.87	7461969
313	Phosphorylation	AQKQEAFSIRMSQLE HHHHHHHHHHHHHHH	19.14	20873877
317	Phosphorylation	EAFSIRMSQLEVKEK HHHHHHHHHHHHHHH	23.05	20068231
322	2-Hydroxyisobutyrylation	RMSQLEVKEKELNKL HHHHHHHHHHHHHHH	54.41	-
330	2-Hydroxyisobutyrylation	EKELNKLKQESDQLV HHHHHHHHHHHHHHH	54.34	-
330	Ubiquitination	EKELNKLKQESDQLV HHHHHHHHHHHHHHH	54.34	-
333	Phosphorylation	LNKLKQESDQLVLNQ HHHHHHHHHHHHHHC	28.32	20873877
393	Ubiquitination	QSTEAYLKGLQDSIR HHHHHHHHHHHHHHH	44.92	-
398	Phosphorylation	YLKGLQDSIRKKYPC HHHHHHHHHHHHCCC	16.01	20873877
427	Ubiquitination	ELEKEREKILEYKRQ HHHHHHHHHHHHHHH	59.83	-
441	Ubiquitination	QVQNLVNKSKKIVQL HHHHHHHHCCHHHCC	57.06	-
442	Phosphorylation	VQNLVNKSKKIVQLK HHHHHHHCCHHHCCC	33.70	21406692
449	Ubiquitination	SKKIVQLKPRNPDYR CCHHHCCCCCCCCCC	25.49	-
455	Phosphorylation	LKPRNPDYRSNKPII CCCCCCCCCCCCCHH	19.73	30622161
457	Phosphorylation	PRNPDYRSNKPIILR CCCCCCCCCCCHHHH	42.87	30622161
459	Acetylation	NPDYRSNKPIILRAL CCCCCCCCCHHHHHH	38.55	26051181
459	Malonylation	NPDYRSNKPIILRAL CCCCCCCCCHHHHHH	38.55	26320211
459	Ubiquitination	NPDYRSNKPIILRAL CCCCCCCCCHHHHHH	38.55	-
470	Acetylation	LRALCDYKQDQKIVH HHHHCCCCCCCCCEE	33.86	26051181
478	Ubiquitination	QDQKIVHKGDECILK CCCCCEECCCCEEEC	58.10	-
485	Acetylation	KGDECILKDNNERSK CCCCEEECCCCCCCC	38.20	26051181
529	Phosphorylation	LSCKIEQYYEAILAL CHHHHHHHHHHHHHH	7.18	27067055
530	Phosphorylation	SCKIEQYYEAILALW HHHHHHHHHHHHHHH	9.89	27067055
564	Phosphorylation	IEKIRAMTIAKLKTM HHHHHHHHHHHHHHC	19.46	24719451
567	2-Hydroxyisobutyrylation	IRAMTIAKLKTMRQE HHHHHHHHHHHCCHH	46.82	-
597	Phosphorylation	FIRNSQGSEMFGDDD HHHCCCCCCCCCCHH	20.46	20873877
607	Ubiquitination	FGDDDKRKIQSQFTD CCCHHHHHHHHHCHH	51.33	-
610	Phosphorylation	DDKRKIQSQFTDAQK HHHHHHHHHCHHHHH	30.63	-
613	Phosphorylation	RKIQSQFTDAQKHYQ HHHHHHCHHHHHHHE	23.84	-
619	Phosphorylation	FTDAQKHYQTLVIQL CHHHHHHHEEEEEEC	15.38	24043423
621	Phosphorylation	DAQKHYQTLVIQLPG HHHHHHEEEEEECCC	18.80	24043423
629	Phosphorylation	LVIQLPGYPQHQTVT EEEECCCCCCCCEEE	9.59	24043423
634	Phosphorylation	PGYPQHQTVTTTEIT CCCCCCCEEECEEEE	20.07	24043423
636	Phosphorylation	YPQHQTVTTTEITHH CCCCCEEECEEEECC	31.24	24043423
637	Phosphorylation	PQHQTVTTTEITHHG CCCCEEECEEEECCC	20.35	24043423
638	Phosphorylation	QHQTVTTTEITHHGT CCCEEECEEEECCCC	18.94	24043423
641	Phosphorylation	TVTTTEITHHGTCQD EEECEEEECCCCCCC	11.11	24043423
645	Phosphorylation	TEITHHGTCQDVNHN EEEECCCCCCCCCCC	11.57	24043423
666	Phosphorylation	RENDKQETWMLMELQ CCCHHHHHHHHHHHH	17.43	24043423
689	Acetylation	CEGRMTLKNLPLADQ CCCCCEECCCCCCCC	47.47	26051181
689	Ubiquitination	CEGRMTLKNLPLADQ CCCCCEECCCCCCCC	47.47	-
698	Phosphorylation	LPLADQGSSHHITVK CCCCCCCCCCCEEEE	22.36	28348404
699	Phosphorylation	PLADQGSSHHITVKI CCCCCCCCCCEEEEH	26.38	28348404
703	Phosphorylation	QGSSHHITVKINELK CCCCCCEEEEHHHHH	16.05	20873877
710	Ubiquitination	TVKINELKSVQNDSQ EEEHHHHHHCCCHHH	42.26	-
727	Methylation	AEVLNQLKDMLANFR HHHHHHHHHHHHHCC	31.18	-
738	Acetylation	ANFRGSEKYCYLQNE HHCCCCCCCHHHHHH	42.17	26051181
738	Ubiquitination	ANFRGSEKYCYLQNE HHCCCCCCCHHHHHH	42.17	-
792	Phosphorylation	KVYEARLTEEETVCL HHHHHCCCCCCEEEE	35.48	28270605
796	Phosphorylation	ARLTEEETVCLDLDK HCCCCCCEEEECHHH	21.57	28270605
803	Acetylation	TVCLDLDKVEAYRCG EEEECHHHHHHHHCC	49.63	26051181
803	Ubiquitination	TVCLDLDKVEAYRCG EEEECHHHHHHHHCC	49.63	-
807	Phosphorylation	DLDKVEAYRCGLKKI CHHHHHHHHCCCHHH	7.91	29083192
815	Ubiquitination	RCGLKKIKNDLNLKK HCCCHHHHCCCCHHH	53.97	-
821	2-Hydroxyisobutyrylation	IKNDLNLKKSLLATM HHCCCCHHHHHHHHH	38.96	-
821	Acetylation	IKNDLNLKKSLLATM HHCCCCHHHHHHHHH	38.96	30584483
829	2-Hydroxyisobutyrylation	KSLLATMKTELQKAQ HHHHHHHHHHHHHHH	34.20	-
829	Acetylation	KSLLATMKTELQKAQ HHHHHHHHHHHHHHH	34.20	26051181
829	Ubiquitination	KSLLATMKTELQKAQ HHHHHHHHHHHHHHH	34.20	-
834	Ubiquitination	TMKTELQKAQQIHSQ HHHHHHHHHHHHHHC	61.87	-
855	Acetylation	LYDLDLGKFGEKVTQ CEECCCHHHHHHHHH	58.45	26051181
855	Ubiquitination	LYDLDLGKFGEKVTQ CEECCCHHHHHHHHH	58.45	-
859	Ubiquitination	DLGKFGEKVTQLTDR CCHHHHHHHHHHHHH	51.46	-
866	Methylation	KVTQLTDRWQRIDKQ HHHHHHHHHHHHHHH	26.62	-
872	Acetylation	DRWQRIDKQIDFRLW HHHHHHHHHHHHHHH	46.94	26051181
872	Ubiquitination	DRWQRIDKQIDFRLW HHHHHHHHHHHHHHH	46.94	-
883	Ubiquitination	FRLWDLEKQIKQLRN HHHHCHHHHHHHHHC	65.70	-
900	Acetylation	DNYQAFCKWLYDAKR HHHHHHHHHHHHHHH	33.51	26051181
900	Ubiquitination	DNYQAFCKWLYDAKR HHHHHHHHHHHHHHH	33.51	-
906	Acetylation	CKWLYDAKRRQDSLE HHHHHHHHHHHHHHH	45.26	27452117
911	Phosphorylation	DAKRRQDSLESMKFG HHHHHHHHHHHCCCC	26.21	24719451
914	Phosphorylation	RRQDSLESMKFGDSN HHHHHHHHCCCCCHH	32.34	-
916	Acetylation	QDSLESMKFGDSNTV HHHHHHCCCCCHHHH	56.31	26051181
916	Ubiquitination	QDSLESMKFGDSNTV HHHHHHCCCCCHHHH	56.31	-
931	Malonylation	MRFLNEQKNLHSEIS HHHHHHCCCHHHHHC	56.13	26320211
931	Ubiquitination	MRFLNEQKNLHSEIS HHHHHHCCCHHHHHC	56.13	21890473
931 (in isoform 1)	Ubiquitination	-	56.13	21890473
931 (in isoform 2)	Ubiquitination	-	56.13	21890473
940	2-Hydroxyisobutyrylation	LHSEISGKRDKSEEV HHHHHCCCCCCHHHH	51.11	-
940	Acetylation	LHSEISGKRDKSEEV HHHHHCCCCCCHHHH	51.11	26051181
940	Ubiquitination	LHSEISGKRDKSEEV HHHHHCCCCCCHHHH	51.11	-
943	Acetylation	EISGKRDKSEEVQKI HHCCCCCCHHHHHHH	64.89	26051181
944	Phosphorylation	ISGKRDKSEEVQKIA HCCCCCCHHHHHHHH	43.19	-
949	Ubiquitination	DKSEEVQKIAELCAN CCHHHHHHHHHHHHH	49.40	21890473
949 (in isoform 1)	Ubiquitination	-	49.40	21890473
949 (in isoform 2)	Ubiquitination	-	49.40	21890473
957	Phosphorylation	IAELCANSIKDYELQ HHHHHHHHCCHHHHH	16.70	25159151
961	Phosphorylation	CANSIKDYELQLASY HHHHCCHHHHHHHHH	17.34	-
1022	Acetylation	RFLSEMLKSLEDLKL HHHHHHHHCHHHHCC	52.24	26051181
1028	2-Hydroxyisobutyrylation	LKSLEDLKLKNTKIE HHCHHHHCCCCCCHH	70.50	-
1028	Acetylation	LKSLEDLKLKNTKIE HHCHHHHCCCCCCHH	70.50	26051181
1028	Ubiquitination	LKSLEDLKLKNTKIE HHCHHHHCCCCCCHH	70.50	-
1033	2-Hydroxyisobutyrylation	DLKLKNTKIEVLEEE HHCCCCCCHHHHHHH	46.38	-
1033	Acetylation	DLKLKNTKIEVLEEE HHCCCCCCHHHHHHH	46.38	26051181
1033	Ubiquitination	DLKLKNTKIEVLEEE HHCCCCCCHHHHHHH	46.38	21906983
1033 (in isoform 1)	Ubiquitination	-	46.38	21890473
1033 (in isoform 2)	Ubiquitination	-	46.38	21890473
1042	Methylation	EVLEEELRLARDANS HHHHHHHHHHHHCCC	29.58	-
1056	Acetylation	SENCNKNKFLDQNLQ CCCCCCCHHHHHHHH	49.25	25825284
1056	Ubiquitination	SENCNKNKFLDQNLQ CCCCCCCHHHHHHHH	49.25	-
1064	Acetylation	FLDQNLQKYQAECSQ HHHHHHHHHHHHHHH	42.36	26051181
1064	Ubiquitination	FLDQNLQKYQAECSQ HHHHHHHHHHHHHHH	42.36	-
1065	Phosphorylation	LDQNLQKYQAECSQF HHHHHHHHHHHHHHH	10.45	28152594
1073	Acetylation	QAECSQFKAKLASLE HHHHHHHHHHHHCHH	36.65	26051181
1073	Methylation	QAECSQFKAKLASLE HHHHHHHHHHHHCHH	36.65	-
1073	Ubiquitination	QAECSQFKAKLASLE HHHHHHHHHHHHCHH	36.65	-
1075	Acetylation	ECSQFKAKLASLEEL HHHHHHHHHHCHHHH	45.22	26051181
1075	Ubiquitination	ECSQFKAKLASLEEL HHHHHHHHHHCHHHH	45.22	-
1078	Phosphorylation	QFKAKLASLEELKRQ HHHHHHHCHHHHHHH	46.91	22985185
1083	2-Hydroxyisobutyrylation	LASLEELKRQAELDG HHCHHHHHHHHHHCC	45.82	-
1083	Acetylation	LASLEELKRQAELDG HHCHHHHHHHHHHCC	45.82	26051181
1083	Succinylation	LASLEELKRQAELDG HHCHHHHHHHHHHCC	45.82	23954790
1083	Ubiquitination	LASLEELKRQAELDG HHCHHHHHHHHHHCC	45.82	-
1092	Phosphorylation	QAELDGKSAKQNLDK HHHHCCHHHHHHHHH	46.35	22210691
1099	Acetylation	SAKQNLDKCYGQIKE HHHHHHHHHHHHHHH	32.30	26051181
1099	Ubiquitination	SAKQNLDKCYGQIKE HHHHHHHHHHHHHHH	32.30	-
1101	Phosphorylation	KQNLDKCYGQIKELN HHHHHHHHHHHHHHH	20.15	28152594
1105	Acetylation	DKCYGQIKELNEKIT HHHHHHHHHHHHHHH	48.54	26051181
1105	Ubiquitination	DKCYGQIKELNEKIT HHHHHHHHHHHHHHH	48.54	-
1116	Phosphorylation	EKITRLTYEIEDEKR HHHHHHHHHCCCHHH	21.36	22817900
1122	Acetylation	TYEIEDEKRRRKSVE HHHCCCHHHHHHCHH	64.62	26051181
1126	Ubiquitination	EDEKRRRKSVEDRFD CCHHHHHHCHHHHHH	57.98	-
1127	Phosphorylation	DEKRRRKSVEDRFDQ CHHHHHHCHHHHHHH	29.00	28355574
1127 (in isoform 2)	Phosphorylation	-	29.00	-
1136	Acetylation	EDRFDQQKNDYDQLQ HHHHHHHHCCHHHHH	46.26	26051181
1136	Ubiquitination	EDRFDQQKNDYDQLQ HHHHHHHHCCHHHHH	46.26	-
1139	Phosphorylation	FDQQKNDYDQLQKAR HHHHHCCHHHHHHHH	18.25	23927012
1144	Acetylation	NDYDQLQKARQCEKE CCHHHHHHHHHHHHH	54.88	26051181
1144	Ubiquitination	NDYDQLQKARQCEKE CCHHHHHHHHHHHHH	54.88	-
1150	Acetylation	QKARQCEKENLGWQK HHHHHHHHHCCCHHH	60.57	26051181
1157	Acetylation	KENLGWQKLESEKAI HHCCCHHHHHHHHHH	47.95	26051181
1157	Ubiquitination	KENLGWQKLESEKAI HHCCCHHHHHHHHHH	47.95	-
1167	Acetylation	SEKAIKEKEYEIERL HHHHHHHHHHHHHHH	61.67	20167786
1169	Phosphorylation	KAIKEKEYEIERLRV HHHHHHHHHHHHHHH	33.02	22817900
1183	Phosphorylation	VLLQEEGTRKREYEN HHHHHCCCCHHHHHH	35.98	21406692
1185	Ubiquitination	LQEEGTRKREYENEL HHHCCCCHHHHHHHH	49.79	-
1188	Phosphorylation	EGTRKREYENELAKV CCCCHHHHHHHHHHH	28.25	20068231
1199	Phosphorylation	LAKVRNHYNEEMSNL HHHHHHHHHHHHHHH	28.02	20860994
1209	2-Hydroxyisobutyrylation	EMSNLRNKYETEINI HHHHHHHHHHHHEEE	37.72	-
1209	Acetylation	EMSNLRNKYETEINI HHHHHHHHHHHHEEE	37.72	26051181
1209	Ubiquitination	EMSNLRNKYETEINI HHHHHHHHHHHHEEE	37.72	-
1210	Phosphorylation	MSNLRNKYETEINIT HHHHHHHHHHHEEEC	31.47	21406692
1212	Phosphorylation	NLRNKYETEINITKT HHHHHHHHHEEECHH	38.79	21406692
1217	Phosphorylation	YETEINITKTTIKEI HHHHEEECHHHHHHH	20.18	21406692
1220	Phosphorylation	EINITKTTIKEISMQ HEEECHHHHHHHHCC	31.44	22817900
1222	Ubiquitination	NITKTTIKEISMQKE EECHHHHHHHHCCCC	47.07	-
1225	Phosphorylation	KTTIKEISMQKEDDS HHHHHHHHCCCCCCC	19.09	17287340
1228	Acetylation	IKEISMQKEDDSKNL HHHHHCCCCCCCHHH	55.24	26051181
1232	O-linked_Glycosylation	SMQKEDDSKNLRNQL HCCCCCCCHHHHHHH	35.45	23301498
1241	Methylation	NLRNQLDRLSRENRD HHHHHHHHHHHHCHH	43.06	-
1250	2-Hydroxyisobutyrylation	SRENRDLKDEIVRLN HHHCHHHHHHHHHHH	58.57	-
1250	Ubiquitination	SRENRDLKDEIVRLN HHHCHHHHHHHHHHH	58.57	21906983
1250 (in isoform 1)	Ubiquitination	-	58.57	21890473
1259	Phosphorylation	EIVRLNDSILQATEQ HHHHHHHHHHHHHHH	24.91	25159151
1282	Phosphorylation	LQQKACGSEIMQKKQ HHHHHHCHHHHHHHH	24.67	23312004
1287	Acetylation	CGSEIMQKKQHLEIE HCHHHHHHHHHHHHH	36.70	26051181
1303	Phosphorylation	KQVMQQRSEDNARHK HHHHHHHHHHHHHHH	44.99	24505115
1310	Ubiquitination	SEDNARHKQSLEEAA HHHHHHHHHHHHHHH	35.71	-
1319	Phosphorylation	SLEEAAKTIQDKNKE HHHHHHHHHHHHHHH	21.10	-
1323	2-Hydroxyisobutyrylation	AAKTIQDKNKEIERL HHHHHHHHHHHHHHH	54.25	-
1344	Phosphorylation	EAKRRWEYENELSKV HHHHHHHHHHHHHHH	19.66	20860994
1350	Ubiquitination	EYENELSKVRNNYDE HHHHHHHHHHCCCCH	58.81	-
1355	Phosphorylation	LSKVRNNYDEEIISL HHHHHCCCCHHHHHH	28.42	27642862
1361	Phosphorylation	NYDEEIISLKNQFET CCCHHHHHHHHHHHC	38.66	20873877
1373	Phosphorylation	FETEINITKTTIHQL HHCEEEECCEEEHHH	20.18	20860994
1381	Phosphorylation	KTTIHQLTMQKEEDT CEEEHHHHCCCCCCC	15.81	20068231
1384	Acetylation	IHQLTMQKEEDTSGY EHHHHCCCCCCCCCH	52.85	26051181
1391	Phosphorylation	KEEDTSGYRAQIDNL CCCCCCCHHHHHHHH	11.53	-
1399	O-linked_Glycosylation	RAQIDNLTRENRSLS HHHHHHHHHHCCCHH	42.04	23301498
1410	Succinylation	RSLSEEIKRLKNTLT CCHHHHHHHHHHHHH	55.76	23954790
1410	Ubiquitination	RSLSEEIKRLKNTLT CCHHHHHHHHHHHHH	55.76	-
1415	Phosphorylation	EIKRLKNTLTQTTEN HHHHHHHHHHHHHHH	29.60	20068231
1417	Phosphorylation	KRLKNTLTQTTENLR HHHHHHHHHHHHHHH	23.10	20068231
1418 (in isoform 2)	Phosphorylation	-	49.92	-
1419	Phosphorylation	LKNTLTQTTENLRRV HHHHHHHHHHHHHHH	30.73	20068231
1420	Phosphorylation	KNTLTQTTENLRRVE HHHHHHHHHHHHHHH	17.04	20068231
1425 (in isoform 2)	Phosphorylation	-	43.28	-
1434	Ubiquitination	EEDIQQQKATGSEVS HHHHHHHHHHCCHHH	43.51	-
1436	Phosphorylation	DIQQQKATGSEVSQR HHHHHHHHCCHHHHH	48.56	20068231
1438	Phosphorylation	QQQKATGSEVSQRKQ HHHHHHCCHHHHHHH	30.39	20068231
1441	Phosphorylation	KATGSEVSQRKQQLE HHHCCHHHHHHHHHH	21.88	20068231
1472 (in isoform 2)	Phosphorylation	-	15.55	-
1487	2-Hydroxyisobutyrylation	NKEIERLKQLIDKET HHHHHHHHHHHCHHC	49.64	-
1492	Acetylation	RLKQLIDKETNDRKC HHHHHHCHHCCCCHH	60.49	26051181
1512	Phosphorylation	ARLQRVQYDLQKANS HHHHHHHHHHHHHCC	18.76	-
1524	Phosphorylation	ANSSATETINKLKVQ HCCCHHHHHHHHHHC	26.04	20860994
1527	Acetylation	SATETINKLKVQEQE CHHHHHHHHHHCHHH	45.92	26051181
1527	Ubiquitination	SATETINKLKVQEQE CHHHHHHHHHHCHHH	45.92	-
1529	Ubiquitination	TETINKLKVQEQELT HHHHHHHHHCHHHHH	43.40	-
1542	Phosphorylation	LTRLRIDYERVSQER HHHHHCCHHHHCCCC	11.85	28152594
1552	2-Hydroxyisobutyrylation	VSQERTVKDQDITRF HCCCCCCCHHHHHHH	49.40	-
1552	Ubiquitination	VSQERTVKDQDITRF HCCCCCCCHHHHHHH	49.40	-
1570	Ubiquitination	LKELQLQKQKVEEEL HHHHHHHHHHHHHHH	61.76	-
1583	Phosphorylation	ELNRLKRTASEDSCK HHHHHHHHCCHHHHH	32.71	20860994
1585	Phosphorylation	NRLKRTASEDSCKRK HHHHHHCCHHHHHHH	41.13	-
1593	Acetylation	EDSCKRKKLEEELEG HHHHHHHHHHHHHHH	66.23	26051181
1593	Malonylation	EDSCKRKKLEEELEG HHHHHHHHHHHHHHH	66.23	26320211
1606	Ubiquitination	EGMRRSLKEQAIKIT HHHHHHHHHHHHHHH	49.37	-
1608 (in isoform 2)	Phosphorylation	-	46.96	-
1610 (in isoform 2)	Phosphorylation	-	3.11	-
1613	Phosphorylation	KEQAIKITNLTQQLE HHHHHHHHCHHHHHH	21.12	-
1623	Phosphorylation	TQQLEQASIVKKRSE HHHHHHHHHHCCCCH	27.84	27499020
1629	Phosphorylation	ASIVKKRSEDDLRQQ HHHHCCCCHHHHHHH	55.01	23312004
1658	Phosphorylation	QEELRRLSSEVEALR HHHHHHHHHHHHHHH	23.73	23927012
1659	Phosphorylation	EELRRLSSEVEALRR HHHHHHHHHHHHHHH	50.70	24732914
1676	Ubiquitination	LQEQESVKQAHLRNE HHHHHHHHHHHHHHH	51.55	-
1676 (in isoform 2)	Phosphorylation	-	51.55	-
1687	Acetylation	LRNEHFQKAIEDKSR HHHHHHHHHHHHHHC	50.84	26051181
1700	Ubiquitination	SRSLNESKIEIERLQ HCCCCHHHHHHHHHH	37.87	-
1708	Phosphorylation	IEIERLQSLTENLTK HHHHHHHHHHHHCCH	41.68	25394399
1710	Phosphorylation	IERLQSLTENLTKEH HHHHHHHHHHCCHHH	28.24	23312004
1714	Phosphorylation	QSLTENLTKEHLMLE HHHHHHCCHHHHCHH	46.07	22817900
1728	Methylation	EEELRNLRLEYDDLR HHHHHHCCCCHHHHH	29.08	-
1735	Methylation	RLEYDDLRRGRSEAD CCCHHHHHCCCCCCC	46.10	-
1740 (in isoform 2)	Phosphorylation	-	55.95	-
1745	Ubiquitination	RSEADSDKNATILEL CCCCCCCCCCCHHHH	53.05	-
1789	Acetylation	QEIEKFQKQALEASN HHHHHHHHHHHHHHH	40.44	26051181
1789	Ubiquitination	QEIEKFQKQALEASN HHHHHHHHHHHHHHH	40.44	-
1793 (in isoform 2)	Ubiquitination	-	53.73	21890473
1795	Phosphorylation	QKQALEASNRIQESK HHHHHHHHHHHHHHH	19.78	20068231
1802	"N6,N6-dimethyllysine"	SNRIQESKNQCTQVV HHHHHHHHHHHHHHH	50.73	-
1802	2-Hydroxyisobutyrylation	SNRIQESKNQCTQVV HHHHHHHHHHHHHHH	50.73	-
1802	Methylation	SNRIQESKNQCTQVV HHHHHHHHHHHHHHH	50.73	-
1802	Ubiquitination	SNRIQESKNQCTQVV HHHHHHHHHHHHHHH	50.73	-
1814	Phosphorylation	QVVQERESLLVKIKV HHHHHHHHHHHHHHH	32.97	28555341
1818	Acetylation	ERESLLVKIKVLEQD HHHHHHHHHHHHHHH	36.46	26051181
1818	Ubiquitination	ERESLLVKIKVLEQD HHHHHHHHHHHHHHH	36.46	-
1820	2-Hydroxyisobutyrylation	ESLLVKIKVLEQDKA HHHHHHHHHHHHHHH	34.74	-
1820	Malonylation	ESLLVKIKVLEQDKA HHHHHHHHHHHHHHH	34.74	26320211
1820	Ubiquitination	ESLLVKIKVLEQDKA HHHHHHHHHHHHHHH	34.74	-
1826	Ubiquitination	IKVLEQDKARLQRLE HHHHHHHHHHHHHHH	34.79	-
1840	Ubiquitination	EDELNRAKSTLEAET HHHHHHHHHHHHHHH	40.51	-
1841	Phosphorylation	DELNRAKSTLEAETR HHHHHHHHHHHHHHH	36.92	22617229
1842	Phosphorylation	ELNRAKSTLEAETRV HHHHHHHHHHHHHHH	28.10	22617229
1857	Acetylation	KQRLECEKQQIQNDL HHHHHHHHHHHHHHH	60.19	26051181
1857	Ubiquitination	KQRLECEKQQIQNDL HHHHHHHHHHHHHHH	60.19	-
1861 (in isoform 2)	Phosphorylation	-	32.80	-
1868	Ubiquitination	QNDLNQWKTQYSRKE HHHHHHHHHHHHHHH	18.91	-
1949	Phosphorylation	LRQRPYGSHRETQTE HHCCCCCCCCCCCCE	17.33	27251275
1950 (in isoform 2)	Phosphorylation	-	27.51	-
1952 (in isoform 2)	Phosphorylation	-	39.58	-
1953	Phosphorylation	PYGSHRETQTECEWT CCCCCCCCCCEEEEE	40.52	27251275
1954 (in isoform 2)	Phosphorylation	-	30.46	-
1955	Phosphorylation	GSHRETQTECEWTVD CCCCCCCCEEEEEEC	50.45	27251275
1956 (in isoform 2)	Phosphorylation	-	22.18	-
1965	Ubiquitination	EWTVDTSKLVFDGLR EEEECHHHHHHHCHH	51.25	-
1981	Phosphorylation	KVTAMQLYECQLIDK HCHHHHHHHCCCCCH	9.58	20049867
1988	Acetylation	YECQLIDKTTLDKLL HHCCCCCHHHHHHHH	36.09	26051181
1993	2-Hydroxyisobutyrylation	IDKTTLDKLLKGKKS CCHHHHHHHHCCCCC	59.85	-
1993	Acetylation	IDKTTLDKLLKGKKS CCHHHHHHHHCCCCC	59.85	26051181
1993	Malonylation	IDKTTLDKLLKGKKS CCHHHHHHHHCCCCC	59.85	26320211
1996 (in isoform 2)	Phosphorylation	-	78.21	-
2000	Phosphorylation	KLLKGKKSVEEVASE HHHCCCCCHHHHHHH	37.94	29743597
2004 (in isoform 2)	Phosphorylation	-	4.49	-
2006	Phosphorylation	KSVEEVASEIQPFLR CCHHHHHHHHHHHHC	40.17	18491316
2007 (in isoform 2)	Phosphorylation	-	35.59	-
2008 (in isoform 2)	Phosphorylation	-	6.13	-
2009 (in isoform 2)	Phosphorylation	-	20.74	-
2011 (in isoform 2)	Phosphorylation	-	4.10	-
2017	Phosphorylation	PFLRGAGSIAGASAS HHHCCCCCCCCCCCC	14.55	19691289
2022	Phosphorylation	AGSIAGASASPKEKY CCCCCCCCCCHHHHC	28.50	25159151
2024	Phosphorylation	SIAGASASPKEKYSL CCCCCCCCHHHHCCH	33.73	25159151
2026	Acetylation	AGASASPKEKYSLVE CCCCCCHHHHCCHHH	65.43	26051181
2029	Phosphorylation	SASPKEKYSLVEAKR CCCHHHHCCHHHHHH	14.34	28152594
2030	Phosphorylation	ASPKEKYSLVEAKRK CCHHHHCCHHHHHHH	36.69	24732914
2041	Phosphorylation	AKRKKLISPESTVML HHHHCCCCHHHHHHH	32.81	28348404
2044	Phosphorylation	KKLISPESTVMLLEA HCCCCHHHHHHHHHH	29.68	28348404
2045	Phosphorylation	KLISPESTVMLLEAQ CCCCHHHHHHHHHHH	14.31	28348404
2066	Ubiquitination	IDPHRNEKLTVDSAI CCCCCCCCCCCCHHH	53.67	-
2068	Phosphorylation	PHRNEKLTVDSAIAR CCCCCCCCCCHHHHH	33.08	20873877
2071	Phosphorylation	NEKLTVDSAIARDLI CCCCCCCHHHHHHCC	19.76	20873877
2083	Methylation	DLIDFDDRQQIYAAE HCCCCCHHHHHHHHH	31.95	-
2087	Phosphorylation	FDDRQQIYAAEKAIT CCHHHHHHHHHHHHC	8.74	-
2103	Ubiquitination	FDDPFSGKTVSVSEA CCCCCCCCEECHHHH	44.55	-
2108	Phosphorylation	SGKTVSVSEAIKKNL CCCEECHHHHHHHCC	17.50	-
2112	2-Hydroxyisobutyrylation	VSVSEAIKKNLIDRE ECHHHHHHHCCCCHH	42.53	-
2145	Ubiquitination	VNSVFLPKDVALARG CCCCCCCHHHHHHCC	67.96	-
2159	Phosphorylation	GLIDRDLYRSLNDPR CCCCHHHHHHCCCCC	11.49	24670416
2161	Phosphorylation	IDRDLYRSLNDPRDS CCHHHHHHCCCCCHH	20.26	22817900
2170	Ubiquitination	NDPRDSQKNFVDPVT CCCCHHCCCCCCCCC	57.20	-
2187	Acetylation	KVSYVQLKERCRIEP EEEEEEHHHHCCCCC	26.48	26051181
2202	Phosphorylation	HTGLLLLSVQKRSMS CCCEEEEEEECCCCC	23.59	25159151
2207	Phosphorylation	LLSVQKRSMSFQGIR EEEEECCCCCCCCCC	26.30	30266825
2209	Phosphorylation	SVQKRSMSFQGIRQP EEECCCCCCCCCCCC	18.70	19664994
2216 (in isoform 2)	Phosphorylation	-	17.56	-
2218	Phosphorylation	QGIRQPVTVTELVDS CCCCCCEEEEHHHHC	28.52	23836654
2218 (in isoform 2)	Phosphorylation	-	28.52	-
2220	Phosphorylation	IRQPVTVTELVDSGI CCCCEEEEHHHHCCC	17.78	23836654
2221 (in isoform 2)	Phosphorylation	-	42.32	-
2222 (in isoform 2)	Phosphorylation	-	3.66	-
2225	Phosphorylation	TVTELVDSGILRPST EEEHHHHCCCCCCCC	21.91	23836654
2226 (in isoform 2)	Phosphorylation	-	20.63	-
2228 (in isoform 2)	Phosphorylation	-	8.21	-
2230 (in isoform 2)	Phosphorylation	-	30.79	-
2231	Phosphorylation	DSGILRPSTVNELES HCCCCCCCCCCCHHC	38.26	25159151
2232	Phosphorylation	SGILRPSTVNELESG CCCCCCCCCCCHHCC	29.99	25627689
2234 (in isoform 2)	Phosphorylation	-	48.50	-
2242	Phosphorylation	ELESGQISYDEVGER CHHCCCCCHHHHHHH	20.74	28348404
2250 (in isoform 2)	Phosphorylation	-	4.34	-
2251	Acetylation	DEVGERIKDFLQGSS HHHHHHHHHHHHCCC	48.96	26051181
2254 (in isoform 2)	Phosphorylation	-	8.93	-
2257	Phosphorylation	IKDFLQGSSCIAGIY HHHHHHCCCCHHHCC	14.74	20873877
2257 (in isoform 2)	Phosphorylation	-	14.74	-
2258	Phosphorylation	KDFLQGSSCIAGIYN HHHHHCCCCHHHCCC	19.16	20873877
2258 (in isoform 2)	Phosphorylation	-	19.16	-
2259 (in isoform 2)	Phosphorylation	-	2.37	-
2264	Phosphorylation	SSCIAGIYNETTKQK CCCHHHCCCHHHHHH	13.16	-
2268 (in isoform 2)	Phosphorylation	-	25.87	-
2269 (in isoform 2)	Phosphorylation	-	53.51	-
2271	Ubiquitination	YNETTKQKLGIYEAM CCHHHHHHCCHHHHH	50.68	-
2275	Phosphorylation	TKQKLGIYEAMKIGL HHHHCCHHHHHHHCC	8.88	21945579
2316	Phosphorylation	RLPVEEAYKRGLVGI CCCHHHHHHCCCCCH	12.42	-
2317	Acetylation	LPVEEAYKRGLVGIE CCHHHHHHCCCCCHH	47.22	26051181
2317	Ubiquitination	LPVEEAYKRGLVGIE CCHHHHHHCCCCCHH	47.22	-
2326	2-Hydroxyisobutyrylation	GLVGIEFKEKLLSAE CCCCHHHHHHHHCCH	40.94	-
2328	2-Hydroxyisobutyrylation	VGIEFKEKLLSAERA CCHHHHHHHHCCHHH	56.15	-
2328	Ubiquitination	VGIEFKEKLLSAERA CCHHHHHHHHCCHHH	56.15	-
2331	Phosphorylation	EFKEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	24719451
2337	Phosphorylation	LSAERAVTGYNDPET HCCHHHHCCCCCCCC	32.72	22210691
2339	Phosphorylation	AERAVTGYNDPETGN CHHHHCCCCCCCCCC	13.66	17081983
2349	Phosphorylation	PETGNIISLFQAMNK CCCCCHHHHHHHHCH	21.23	22210691
2361	2-Hydroxyisobutyrylation	MNKELIEKGHGIRLL HCHHHHHCCCCCEEE	49.57	-
2361	Ubiquitination	MNKELIEKGHGIRLL HCHHHHHCCCCCEEE	49.57	-
2381	Acetylation	TGGIIDPKESHRLPV CCCCCCHHHHCCCCC	69.01	26051181
2383	Phosphorylation	GIIDPKESHRLPVDI CCCCHHHHCCCCCHH	21.75	20873877
2393	2-Hydroxyisobutyrylation	LPVDIAYKRGYFNEE CCCHHHHHCCCCCHH	30.26	-
2393	Acetylation	LPVDIAYKRGYFNEE CCCHHHHHCCCCCHH	30.26	26051181
2393	Ubiquitination	LPVDIAYKRGYFNEE CCCHHHHHCCCCCHH	30.26	2190698
2393 (in isoform 1)	Ubiquitination	-	30.26	21890473
2402	Phosphorylation	GYFNEELSEILSDPS CCCCHHHHHHHCCCC	26.35	20873877
2406	Phosphorylation	EELSEILSDPSDDTK HHHHHHHCCCCCCCC	53.81	20873877
2409	Phosphorylation	SEILSDPSDDTKGFF HHHHCCCCCCCCCCC	53.78	20873877
2412	Phosphorylation	LSDPSDDTKGFFDPN HCCCCCCCCCCCCCC	37.75	20873877
2413	Acetylation	SDPSDDTKGFFDPNT CCCCCCCCCCCCCCH	61.79	26051181
2426	Phosphorylation	NTEENLTYLQLKERC CHHHCEEHHHHHHHH	8.80	27642862
2430	Acetylation	NLTYLQLKERCIKDE CEEHHHHHHHHCCCC	30.10	26051181
2430	Ubiquitination	NLTYLQLKERCIKDE CEEHHHHHHHHCCCC	30.10	-
2435	Acetylation	QLKERCIKDEETGLC HHHHHHCCCCCCCCE	63.81	26051181
2450	Acetylation	LLPLKEKKKQVQTSQ EEEHHHHHHHCCHHH	49.91	11791235
2455	Phosphorylation	EKKKQVQTSQKNTLR HHHHHCCHHHCCCCC	33.98	28348404
2456	Phosphorylation	KKKQVQTSQKNTLRK HHHHCCHHHCCCCCC	23.28	24719451
2460	Phosphorylation	VQTSQKNTLRKRRVV CCHHHCCCCCCCEEE	34.67	22817900
2473	Phosphorylation	VVIVDPETNKEMSVQ EEEECCCCCCCCCHH	57.91	27174698
2478	Phosphorylation	PETNKEMSVQEAYKK CCCCCCCCHHHHHHC	23.03	25159151
2483	Phosphorylation	EMSVQEAYKKGLIDY CCCHHHHHHCCCCCH	16.69	27174698
2484	Acetylation	MSVQEAYKKGLIDYE CCHHHHHHCCCCCHH	47.62	26051181
2490	Phosphorylation	YKKGLIDYETFKELC HHCCCCCHHHHHHHH	15.18	27642862
2523	Ubiquitination	RVVLVDRKTGSQYDI EEEEEECCCCCCCCH	53.42	-
2524	Phosphorylation	VVLVDRKTGSQYDIQ EEEEECCCCCCCCHH	42.85	20873877
2526	Phosphorylation	LVDRKTGSQYDIQDA EEECCCCCCCCHHHH	30.69	28355574
2528	Phosphorylation	DRKTGSQYDIQDAID ECCCCCCCCHHHHHH	19.40	20873877
2536	Acetylation	DIQDAIDKGLVDRKF CHHHHHHHCCCCHHH	48.29	26051181
2536	Ubiquitination	DIQDAIDKGLVDRKF CHHHHHHHCCCCHHH	48.29	-
2542	Acetylation	DKGLVDRKFFDQYRS HHCCCCHHHHHHHHC	46.01	26051181
2547	Phosphorylation	DRKFFDQYRSGSLSL CHHHHHHHHCCCCCH	14.48	23090842
2549	Phosphorylation	KFFDQYRSGSLSLTQ HHHHHHHCCCCCHHH	28.00	25159151
2551	Phosphorylation	FDQYRSGSLSLTQFA HHHHHCCCCCHHHHH	18.94	28355574
2553	Phosphorylation	QYRSGSLSLTQFADM HHHCCCCCHHHHHHH	30.94	28102081
2555	Phosphorylation	RSGSLSLTQFADMIS HCCCCCHHHHHHHHC	20.47	24732914
2562	Phosphorylation	TQFADMISLKNGVGT HHHHHHHCCCCCCCC	27.01	24732914
2569	Phosphorylation	SLKNGVGTSSSMGSG CCCCCCCCCCCCCCC	24.03	20873877
2570	Phosphorylation	LKNGVGTSSSMGSGV CCCCCCCCCCCCCCC	17.94	20068231
2571	Phosphorylation	KNGVGTSSSMGSGVS CCCCCCCCCCCCCCC	24.96	20068231
2572	Phosphorylation	NGVGTSSSMGSGVSD CCCCCCCCCCCCCCC	27.25	20068231
2575	Phosphorylation	GTSSSMGSGVSDDVF CCCCCCCCCCCCCCC	27.64	20068231
2578	Phosphorylation	SSMGSGVSDDVFSSS CCCCCCCCCCCCCCC	31.45	20068231
2583	Phosphorylation	GVSDDVFSSSRHESV CCCCCCCCCCCCCCH	27.53	25159151
2584	Phosphorylation	VSDDVFSSSRHESVS CCCCCCCCCCCCCHH	21.67	25159151
2585	Phosphorylation	SDDVFSSSRHESVSK CCCCCCCCCCCCHHH	36.14	20068231
2589	Phosphorylation	FSSSRHESVSKISTI CCCCCCCCHHHHHHH	26.09	20873877
2591	Phosphorylation	SSRHESVSKISTISS CCCCCCHHHHHHHHH	33.28	20873877
2592	Ubiquitination	SRHESVSKISTISSV CCCCCHHHHHHHHHH	38.22	-
2594	Phosphorylation	HESVSKISTISSVRN CCCHHHHHHHHHHCC	24.35	20068231
2595	Phosphorylation	ESVSKISTISSVRNL CCHHHHHHHHHHCCC	28.49	29116813
2597	Phosphorylation	VSKISTISSVRNLTI HHHHHHHHHHCCCEE	23.91	24670416
2598	Phosphorylation	SKISTISSVRNLTIR HHHHHHHHHCCCEEE	22.65	24670416
2603	Phosphorylation	ISSVRNLTIRSSSFS HHHHCCCEEECCCCC	20.21	22617229
2606	Phosphorylation	VRNLTIRSSSFSDTL HCCCEEECCCCCCCC	26.87	23927012
2607	Phosphorylation	RNLTIRSSSFSDTLE CCCEEECCCCCCCCC	26.08	30278072
2608	Phosphorylation	NLTIRSSSFSDTLEE CCEEECCCCCCCCCC	29.98	23927012
2610	Phosphorylation	TIRSSSFSDTLEESS EEECCCCCCCCCCCC	31.47	30278072
2612	Phosphorylation	RSSSFSDTLEESSPI ECCCCCCCCCCCCCE	34.57	30278072
2616	Phosphorylation	FSDTLEESSPIAAIF CCCCCCCCCCEEEEE	31.85	30278072
2617	Phosphorylation	SDTLEESSPIAAIFD CCCCCCCCCEEEEEE	24.49	30278072
2625	Phosphorylation	PIAAIFDTENLEKIS CEEEEEECCCCCEEE	18.94	24732914
2632	Phosphorylation	TENLEKISITEGIER CCCCCEEECCCCHHH	34.23	20873877
2644	Phosphorylation	IERGIVDSITGQRLL HHHCCCCHHCCHHHH	15.91	20873877
2646	Phosphorylation	RGIVDSITGQRLLEA HCCCCHHCCHHHHHH	31.08	20873877
2657	Phosphorylation	LLEAQACTGGIIHPT HHHHHHCCCCCCCCC	41.27	27732954
2664	Phosphorylation	TGGIIHPTTGQKLSL CCCCCCCCCCCCCCH	29.42	27732954
2665	Phosphorylation	GGIIHPTTGQKLSLQ CCCCCCCCCCCCCHH	41.91	27732954
2670	Phosphorylation	PTTGQKLSLQDAVSQ CCCCCCCCHHHHHHC	30.90	20873877
2676	Phosphorylation	LSLQDAVSQGVIDQD CCHHHHHHCCCCCHH	23.96	20873877
2702	Ubiquitination	FIGFEGVKGKKKMSA HHCCCCCCCCCCCCH	75.71	-
2708	Phosphorylation	VKGKKKMSAAEAVKE CCCCCCCCHHHHHHH	32.95	25159151
2720	Phosphorylation	VKEKWLPYEAGQRFL HHHHCCCHHHHHHHH	19.08	-
2731	Phosphorylation	QRFLEFQYLTGGLVD HHHHHHHHHHCCCCC	16.14	-
2733	Phosphorylation	FLEFQYLTGGLVDPE HHHHHHHHCCCCCHH	25.03	-
2746	Phosphorylation	PEVHGRISTEEAIRK HHHCCCCCHHHHHHH	28.53	21815630
2747	Phosphorylation	EVHGRISTEEAIRKG HHCCCCCHHHHHHHC	35.16	21406692
2767	Phosphorylation	AAQRLQDTSSYAKIL HHHHHHCCCCCHHHH	13.45	28152594
2768	Phosphorylation	AQRLQDTSSYAKILT HHHHHCCCCCHHHHC	29.64	28152594
2769	Phosphorylation	QRLQDTSSYAKILTC HHHHCCCCCHHHHCC	31.07	28152594
2770	Phosphorylation	RLQDTSSYAKILTCP HHHCCCCCHHHHCCC	16.22	28152594
2772	Acetylation	QDTSSYAKILTCPKT HCCCCCHHHHCCCCC	29.98	26051181
2785	Phosphorylation	KTKLKISYKDAINRS CCCCEEEHHHHCCHH	19.16	22817900
2786	Acetylation	TKLKISYKDAINRSM CCCEEEHHHHCCHHH	33.61	26051181
2786	Succinylation	TKLKISYKDAINRSM CCCEEEHHHHCCHHH	33.61	23954790
2786	Ubiquitination	TKLKISYKDAINRSM CCCEEEHHHHCCHHH	33.61	-
2792	O-linked_Glycosylation	YKDAINRSMVEDITG HHHHCCHHHHHHHHH	23.77	23301498
2792	Phosphorylation	YKDAINRSMVEDITG HHHHCCHHHHHHHHH	23.77	20873877
2798	Phosphorylation	RSMVEDITGLRLLEA HHHHHHHHHHHHHHH	42.35	24144214
2807	Phosphorylation	LRLLEAASVSSKGLP HHHHHHHCCCCCCCC	29.58	20873877
2809	Phosphorylation	LLEAASVSSKGLPSP HHHHHCCCCCCCCCC	24.68	20873877
2810	Phosphorylation	LEAASVSSKGLPSPY HHHHCCCCCCCCCCC	28.70	20873877
2811	Ubiquitination	EAASVSSKGLPSPYN HHHCCCCCCCCCCCC	57.89	-
2815	Phosphorylation	VSSKGLPSPYNMSSA CCCCCCCCCCCCCCC	45.09	23927012
2817	Phosphorylation	SKGLPSPYNMSSAPG CCCCCCCCCCCCCCC	28.03	21945579
2820	Phosphorylation	LPSPYNMSSAPGSRS CCCCCCCCCCCCCCC	21.51	22167270
2821	Phosphorylation	PSPYNMSSAPGSRSG CCCCCCCCCCCCCCC	27.93	22167270
2825	Phosphorylation	NMSSAPGSRSGSRSG CCCCCCCCCCCCCCC	23.39	19664994
2826	Methylation	MSSAPGSRSGSRSGS CCCCCCCCCCCCCCC	51.45	-
2827	Phosphorylation	SSAPGSRSGSRSGSR CCCCCCCCCCCCCCC	42.70	23927012
2829	Phosphorylation	APGSRSGSRSGSRSG CCCCCCCCCCCCCCC	25.23	23927012
2830	Methylation	PGSRSGSRSGSRSGS CCCCCCCCCCCCCCC	48.87	-
2831	Phosphorylation	GSRSGSRSGSRSGSR CCCCCCCCCCCCCCC	42.70	23927012
2833	Phosphorylation	RSGSRSGSRSGSRSG CCCCCCCCCCCCCCC	25.23	18669648
2834	Methylation	SGSRSGSRSGSRSGS CCCCCCCCCCCCCCC	48.87	-
2835	Phosphorylation	GSRSGSRSGSRSGSR CCCCCCCCCCCCCCC	42.70	-
2837	Phosphorylation	RSGSRSGSRSGSRSG CCCCCCCCCCCCCCC	25.23	18669648
2838	Methylation	SGSRSGSRSGSRSGS CCCCCCCCCCCCCCC	48.87	-
2839	Phosphorylation	GSRSGSRSGSRSGSR CCCCCCCCCCCCCCC	42.70	-
2841	Phosphorylation	RSGSRSGSRSGSRRG CCCCCCCCCCCCCCC	25.23	-
2843	Phosphorylation	GSRSGSRSGSRRGSF CCCCCCCCCCCCCCE	42.70	-
2845	Phosphorylation	RSGSRSGSRRGSFDA CCCCCCCCCCCCEEC	21.76	30576142
2847	Methylation	GSRSGSRRGSFDATG CCCCCCCCCCEECCC	46.97	-
2849	Phosphorylation	RSGSRRGSFDATGNS CCCCCCCCEECCCCC	20.38	25159151
2853	Phosphorylation	RRGSFDATGNSSYSY CCCCEECCCCCCCEE	38.45	23927012
2856	Phosphorylation	SFDATGNSSYSYSYS CEECCCCCCCEEEEE	31.81	23927012
2857	Phosphorylation	FDATGNSSYSYSYSF EECCCCCCCEEEEEE	23.30	23927012
2858	Phosphorylation	DATGNSSYSYSYSFS ECCCCCCCEEEEEEE	16.08	23663014
2859	Phosphorylation	ATGNSSYSYSYSFSS CCCCCCCEEEEEEEC	15.00	23663014
2860	Phosphorylation	TGNSSYSYSYSFSSS CCCCCCEEEEEEECC	11.91	23663014
2861	Phosphorylation	GNSSYSYSYSFSSSS CCCCCEEEEEEECCC	14.36	23663014
2862	Phosphorylation	NSSYSYSYSFSSSSI CCCCEEEEEEECCCC	12.90	23663014
2863	Phosphorylation	SSYSYSYSFSSSSIG CCCEEEEEEECCCCC	16.83	23663014
2865	Phosphorylation	YSYSYSFSSSSIGH- CEEEEEEECCCCCC-	24.30	23927012
2866	Phosphorylation	SYSYSFSSSSIGH-- EEEEEEECCCCCC--	26.54	20068231
2867	Phosphorylation	YSYSFSSSSIGH--- EEEEEECCCCCC---	25.44	18669648
2868	Phosphorylation	SYSFSSSSIGH---- EEEEECCCCCC----	34.24	20031617

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
2845	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
2849	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
2849	S	Phosphorylation	Kinase	PRKACA	P17612	GPS
2849	S	Phosphorylation	Kinase	PKA-FAMILY	-	GPS
2849	S	Phosphorylation	Kinase	PKA_GROUP	-	PhosphoELM

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
2849	S	Phosphorylation	12802069
Phosphorylation on Ser-2849 probably affects its association with epidermal, simple cytokeratins and VIM intermediate filaments.
2849	S	Phosphorylation	12802069
Ser-2849 is probably phosphorylated by a cAMP-dependent protein kinase.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DESP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
INVO_HUMAN	IVL	physical	8999895
CADH5_HUMAN	CDH5	physical	9739078
PLAK_HUMAN	JUP	physical	9739078
VIME_HUMAN	VIM	physical	9261168
K2C1_HUMAN	KRT1	physical	9261168
DESM_HUMAN	DES	physical	9261168
DESP_HUMAN	DSP	physical	12101406
EVPL_HUMAN	EVPL	physical	22939629
KAD2_HUMAN	AK2	physical	22939629
PSN1_HUMAN	PSEN1	physical	22939629
OVCA2_HUMAN	OVCA2	physical	22939629
VTNC_HUMAN	VTN	physical	22939629
KPCA_HUMAN	PRKCA	physical	22939629
TECR_HUMAN	TECR	physical	22939629
RAB5B_HUMAN	RAB5B	physical	22939629
HNMT_HUMAN	HNMT	physical	22939629
K2C1_HUMAN	KRT1	physical	26344197
K1C16_HUMAN	KRT16	physical	26344197
NP1L4_HUMAN	NAP1L4	physical	26496610
TELO2_HUMAN	TELO2	physical	26496610
SC22A_HUMAN	SEC22A	physical	26496610
HEAT3_HUMAN	HEATR3	physical	26496610
CEP72_HUMAN	CEP72	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
612908	Keratoderma, palmoplantar, striate 2 (SPPK2)
605676	Cardiomyopathy, dilated, with woolly hair and keratoderma (DCWHK)
607450	Arrhythmogenic right ventricular dysplasia, familial, 8 (ARVD8)
607655	Skin fragility-woolly hair syndrome (SFWHS)
609638	Epidermolysis bullosa, lethal acantholytic (EBLA)
615821	Cardiomyopathy, dilated, with woolly hair, keratoderma, and tooth agenesis (DCWHKTA)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DESP_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2606, AND MASSSPECTROMETRY.	19369195 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-178, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-22; SER-165; SER-166;SER-176; SER-2024; SER-2209; SER-2815; SER-2820; SER-2821; SER-2825;SER-2849; THR-2853; SER-2857 AND SER-2868, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2209, AND MASSSPECTROMETRY.	18691976 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2815 AND SER-2825, ANDMASS SPECTROMETRY.	18220336 [Abstract]
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2821, AND MASSSPECTROMETRY.	18187866 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-22 AND SER-2209, ANDMASS SPECTROMETRY.	19007248 [Abstract]
"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry."; Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.; Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1220 AND SER-1225, ANDMASS SPECTROMETRY.	17287340 [Abstract]
"Phosphoproteome analysis of the human mitotic spindle."; Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.; Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-22; SER-176; SER-2815;SER-2820 AND SER-2825, AND MASS SPECTROMETRY.	16565220 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-176; SER-2024; SER-2209;SER-2815 AND SER-2825, AND MASS SPECTROMETRY.	15302935 [Abstract]
"An extensive survey of tyrosine phosphorylation revealing new sitesin human mammary epithelial cells."; Heibeck T.H., Ding S.-J., Opresko L.K., Zhao R., Schepmoes A.A.,Yang F., Tolmachev A.V., Monroe M.E., Camp D.G. II, Smith R.D.,Wiley H.S., Qian W.-J.; J. Proteome Res. 8:3852-3861(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-56, AND MASSSPECTROMETRY.	19534553 [Abstract]
"Multiple reaction monitoring for robust quantitative proteomicanalysis of cellular signaling networks."; Wolf-Yadlin A., Hautaniemi S., Lauffenburger D.A., White F.M.; Proc. Natl. Acad. Sci. U.S.A. 104:5860-5865(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-28 AND TYR-56, AND MASSSPECTROMETRY.	17389395 [Abstract]
"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer."; Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.; Cell 131:1190-1203(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-28; TYR-56 AND TYR-2275,AND MASS SPECTROMETRY.	18083107 [Abstract]

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