ZC21C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZC21C_HUMAN
• UniProt AC: Q53FD0
• Protein Name: Zinc finger C2HC domain-containing protein 1C
• Gene Name: ZC2HC1C
• Organism: Homo sapiens (Human).
• Sequence Length: 456
• Protein Sequence: MAGLQRLASHLPVGVMLPHNTTEAPGPHSAKQDSYEQGDSSQQSLKGHLRNNFQKQLLSNKELILDKVYTHPKWNTQTKARSYSYPHCTGISQQDPESDSQGQGNGLFYSSGPQSWYPKANNQDFIPFTKKRVGVDRAFPLKPMVHRKSCSTGEAGTDGDHNVYPRPPEPREFSSRNFGVRNQGNFSVVGTVLAATQAEKAVANFDRTEWVQIRRLEAAGESLEEEIRRKQILLRGKLKKTEEELRRIQTQKEQAKENENGELQKIILPRSRVKGNKSNTMYKPIFSPEFEFEEEFSRDRREDETWGRSQQNSGPFQFSDYRIQRLKRERLVASNNKIRDPVSEPSVEKFSPPSETPVGALQGSARNSSLSMAPDSSGSSGSIEEPQLGECSHCGRKFLSFRLERHSNICSRMRGSKRKVFDSSRARAKGTELEQYLNWKGPASAKAEPPQKSNWR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	Phosphorylation	HSAKQDSYEQGDSSQ CCCCCCCCCCCCCCH	22.14	-
40	Phosphorylation	DSYEQGDSSQQSLKG CCCCCCCCCHHHHHH	36.55	-
278	Phosphorylation	SRVKGNKSNTMYKPI HHCCCCCCCCCCCCC	41.34	29759185
280	Phosphorylation	VKGNKSNTMYKPIFS CCCCCCCCCCCCCCC	29.03	29759185
282	Phosphorylation	GNKSNTMYKPIFSPE CCCCCCCCCCCCCCC	16.15	29759185
287	Phosphorylation	TMYKPIFSPEFEFEE CCCCCCCCCCCCCCH	25.00	29759185
297	Phosphorylation	FEFEEEFSRDRREDE CCCCHHHCCCCCCCC	36.23	29759185
305	Phosphorylation	RDRREDETWGRSQQN CCCCCCCCCCCCCCC	45.61	-
379	Phosphorylation	MAPDSSGSSGSIEEP CCCCCCCCCCCCCCC	33.21	22468782
380	Phosphorylation	APDSSGSSGSIEEPQ CCCCCCCCCCCCCCC	39.83	22468782
423	Phosphorylation	SKRKVFDSSRARAKG CCCCCCCHHHHHHCC	15.40	28509920
444	Phosphorylation	LNWKGPASAKAEPPQ HCCCCCCCCCCCCCC	33.17	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZC21C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZC21C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZC21C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FSD2_HUMAN	FSD2	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
SPERT_HUMAN	SPERT	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.