dbPTM

CH048_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CH048_HUMAN
UniProt AC	Q96LL4
Protein Name	Uncharacterized protein C8orf48
Gene Name	C8orf48
Organism	Homo sapiens (Human).
Sequence Length	319
Subcellular Localization
Protein Description
Protein Sequence	MAICPELAQTDKSALANLSDETETLKNSTDEVQTSSSFSSSGGRQSSPLTSGSKLEREKQTPSLEQGDTQSELLDYKNYEKKLSKKWINYLKLKDSNFERHQPDTKLPTEITRVSDEELNALQSYCTMKINLIHRRGDSKKKTSSRHKKLHLGLDVEASERDAFSCTVPDELLNRIYFKNMRTTPKQEAAAKQHISYQCPYCNRKRAELALSAFLKQKKTLLESFLLQERIDEHLHTKDFLTRIGEAHQDFPRLSDDPRIIWKRLTEKSHIRYSGFERSETEQKLQRDGNSACHLPFSLPFLKRLTLIKPELVIVNDNV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Phosphorylation	ETETLKNSTDEVQTS HHHHHCCCCCCCCCC	35.33	28674151
29	Phosphorylation	TETLKNSTDEVQTSS HHHHCCCCCCCCCCC	45.64	28674151
34	Phosphorylation	NSTDEVQTSSSFSSS CCCCCCCCCCCCCCC	35.43	28674151
35	Phosphorylation	STDEVQTSSSFSSSG CCCCCCCCCCCCCCC	13.59	30576142
36	Phosphorylation	TDEVQTSSSFSSSGG CCCCCCCCCCCCCCC	38.50	30576142
47	Phosphorylation	SSGGRQSSPLTSGSK CCCCCCCCCCCCCCH	18.65	-
53	Phosphorylation	SSPLTSGSKLEREKQ CCCCCCCCHHHHHHC	33.56	-
177	Phosphorylation	DELLNRIYFKNMRTT HHHHHHHHHCCCCCC	12.79	23917254
184	O-linked_Glycosylation	YFKNMRTTPKQEAAA HHCCCCCCHHHHHHH	20.37	30379171

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CH048_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CH048_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CH048_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
MDFI_HUMAN	MDFI	physical	19060904
KDM1A_HUMAN	KDM1A	physical	23455924

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CH048_HUMAN

Related Literatures of Post-Translational Modification