dbPTM

PARD3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PARD3_HUMAN
UniProt AC	Q8TEW0
Protein Name	Partitioning defective 3 homolog
Gene Name	PARD3 {ECO:0000312\|HGNC:HGNC:16051}
Organism	Homo sapiens (Human).
Sequence Length	1356
Subcellular Localization	Cytoplasm. Endomembrane system . Cell junction . Cell junction, tight junction . Cell junction, adherens junction . Cell membrane . Cytoplasm, cell cortex. Cytoplasm, cytoskeleton . Localized along the cell-cell contact region. Colocalizes with PARD6
Protein Description	Adapter protein involved in asymmetrical cell division and cell polarization processes. [PubMed: 27925688]
Protein Sequence	MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MKVTVCFGR ------CEEEEEECC	58.90	18585271
22	Acetylation	PCGDGHMKVFSLIQQ ECCCCHHHHHHHHHH	34.16	18585281
25	Phosphorylation	DGHMKVFSLIQQAVT CCHHHHHHHHHHHHH	27.79	30108239
25 (in isoform 11)	Phosphorylation	-	27.79	24719451
32	Phosphorylation	SLIQQAVTRYRKAIA HHHHHHHHHHHHHHH	25.62	21406692
44	Phosphorylation	AIAKDPNYWIQVHRL HHHHCCCEEEEEEEC	14.85	27642862
91	Phosphorylation	PHHGGDGTSASSTGT CCCCCCCCCCCCCCC	26.34	24275569
94	Phosphorylation	GGDGTSASSTGTQSP CCCCCCCCCCCCCCC	28.35	24275569
95	Phosphorylation	GDGTSASSTGTQSPE CCCCCCCCCCCCCCC	30.49	24275569
96	Phosphorylation	DGTSASSTGTQSPEI CCCCCCCCCCCCCCC	41.58	24275569
98	Phosphorylation	TSASSTGTQSPEIFG CCCCCCCCCCCCCCC	26.43	22468782
100	Phosphorylation	ASSTGTQSPEIFGSE CCCCCCCCCCCCCCC	25.08	27362937
114	Phosphorylation	ELGTNNVSAFQPYQA CCCCCCCCCCCCEEC	26.03	28464451
119	Phosphorylation	NVSAFQPYQATSEIE CCCCCCCEECCCEEE	10.45	22817900
143	Phosphorylation	MPLHVRRSSDPALIG CCEEEECCCCCCEEE	28.64	29255136
143 (in isoform 11)	Phosphorylation	-	28.64	24719451
144	Phosphorylation	PLHVRRSSDPALIGL CEEEECCCCCCEEEE	45.89	29255136
152	Phosphorylation	DPALIGLSTSVSDSN CCCEEEEECCCCCCC	17.27	23927012
153	Phosphorylation	PALIGLSTSVSDSNF CCEEEEECCCCCCCC	37.88	23927012
154	Phosphorylation	ALIGLSTSVSDSNFS CEEEEECCCCCCCCC	19.09	23927012
156	Phosphorylation	IGLSTSVSDSNFSSE EEEECCCCCCCCCCC	34.78	23927012
156 (in isoform 11)	Phosphorylation	-	34.78	24719451
158	Phosphorylation	LSTSVSDSNFSSEEP EECCCCCCCCCCCCC	32.06	23927012
161	Phosphorylation	SVSDSNFSSEEPSRK CCCCCCCCCCCCCCC	40.88	23927012
162	Phosphorylation	VSDSNFSSEEPSRKN CCCCCCCCCCCCCCC	41.67	24732914
166	Phosphorylation	NFSSEEPSRKNPTRW CCCCCCCCCCCCCCC	60.20	24732914
171	Phosphorylation	EPSRKNPTRWSTTAG CCCCCCCCCCCHHHH	54.91	30266825
174	Phosphorylation	RKNPTRWSTTAGFLK CCCCCCCCHHHHHHH	16.76	30266825
174 (in isoform 11)	Phosphorylation	-	16.76	24719451
175	Phosphorylation	KNPTRWSTTAGFLKQ CCCCCCCHHHHHHHH	17.44	30266825
176	Phosphorylation	NPTRWSTTAGFLKQN CCCCCCHHHHHHHHC	21.19	22167270
181	Methylation	STTAGFLKQNTAGSP CHHHHHHHHCCCCCC	38.96	54405367
184	Phosphorylation	AGFLKQNTAGSPKTC HHHHHHCCCCCCCCC	29.87	25849741
184 (in isoform 3)	Phosphorylation	-	29.87	25849741
184 (in isoform 5)	Phosphorylation	-	29.87	25849741
187	Phosphorylation	LKQNTAGSPKTCDRK HHHCCCCCCCCCCCC	22.28	25849741
187 (in isoform 11)	Phosphorylation	-	22.28	24719451
187 (in isoform 3)	Phosphorylation	-	22.28	25849741
187 (in isoform 5)	Phosphorylation	-	22.28	25849741
199	Phosphorylation	DRKKDENYRSLPRDT CCCCCCCCCCCCCCC	10.26	23403867
201	Phosphorylation	KKDENYRSLPRDTSN CCCCCCCCCCCCCCC	32.16	25159151
207	Phosphorylation	RSLPRDTSNWSNQFQ CCCCCCCCCCHHHHH	40.36	24719451
207 (in isoform 11)	Phosphorylation	-	40.36	24719451
220	Phosphorylation	FQRDNARSSLSASHP HHHHCHHHHHHHCCH	32.97	30266825
220 (in isoform 11)	Phosphorylation	-	32.97	24719451
221	Phosphorylation	QRDNARSSLSASHPM HHHCHHHHHHHCCHH	22.31	30266825
221 (in isoform 11)	Phosphorylation	-	22.31	24719451
223	Phosphorylation	DNARSSLSASHPMVG HCHHHHHHHCCHHHH	29.67	30266825
225	Phosphorylation	ARSSLSASHPMVGKW HHHHHHHCCHHHHHH	25.42	30266825
225 (in isoform 11)	Phosphorylation	-	25.42	24719451
228	Sulfoxidation	SLSASHPMVGKWLEK HHHHCCHHHHHHHHH	5.34	21406390
235	Ubiquitination	MVGKWLEKQEQDEDG HHHHHHHHHHCCCCC	57.89	29967540
294	Methylation	HVVPFSARGGRTLGL EEEECCCCCCHHHHH	47.07	54557919
296	Ubiquitination	VPFSARGGRTLGLLV EECCCCCCHHHHHHH	17.53	23000965
298	Phosphorylation	FSARGGRTLGLLVKR CCCCCCHHHHHHHHH	28.58	-
330	Ubiquitination	CIVRINDGDLRNRRF EEEECCCHHHHCHHH	31.22	23000965
340	Ubiquitination	RNRRFEQAQHMFRQA HCHHHHHHHHHHHHH	8.27	23000965
366	Phosphorylation	PAANKEQYEQLSQSE CCCCHHHHHHHCHHH	13.51	28796482
370	Phosphorylation	KEQYEQLSQSEKNNY HHHHHHHCHHHHHCC	31.21	-
374	Ubiquitination	EQLSQSEKNNYYSSR HHHCHHHHHCCCCCC	56.60	23000965
377	Phosphorylation	SQSEKNNYYSSRFSP CHHHHHCCCCCCCCC	17.70	21945579
378	Phosphorylation	QSEKNNYYSSRFSPD HHHHHCCCCCCCCCC	11.42	21945579
379	Phosphorylation	SEKNNYYSSRFSPDS HHHHCCCCCCCCCCH	12.50	21945579
380	Phosphorylation	EKNNYYSSRFSPDSQ HHHCCCCCCCCCCHH	22.63	21945579
383	Phosphorylation	NYYSSRFSPDSQYID CCCCCCCCCCHHHCC	27.04	19664994
383 (in isoform 11)	Phosphorylation	-	27.04	24719451
386	Phosphorylation	SSRFSPDSQYIDNRS CCCCCCCHHHCCCCC	28.41	21945579
388	Phosphorylation	RFSPDSQYIDNRSVN CCCCCHHHCCCCCCC	17.75	21945579
393	Phosphorylation	SQYIDNRSVNSAGLH HHHCCCCCCCCCCHH	31.72	28857561
396	Phosphorylation	IDNRSVNSAGLHTVQ CCCCCCCCCCHHHHH	22.89	28555341
401	Phosphorylation	VNSAGLHTVQRAPRL CCCCCHHHHHCCCCC	24.31	27732954
417	Phosphorylation	HPPEQIDSHSRLPHS CCHHHCCCCCCCCCC	25.62	28555341
437	Phosphorylation	KPPSAPASAPQNVFS CCCCCCCCCCCCCEE	39.15	22210691
444	Phosphorylation	SAPQNVFSTTVSSGY CCCCCCEECCCCCCC	20.91	28152594
445	Phosphorylation	APQNVFSTTVSSGYN CCCCCEECCCCCCCC	21.54	28152594
446	Phosphorylation	PQNVFSTTVSSGYNT CCCCEECCCCCCCCC	19.72	28152594
448	Phosphorylation	NVFSTTVSSGYNTKK CCEECCCCCCCCCCC	18.89	28152594
449	Phosphorylation	VFSTTVSSGYNTKKI CEECCCCCCCCCCCH	40.74	28152594
451	Phosphorylation	STTVSSGYNTKKIGK ECCCCCCCCCCCHHH	22.93	28152594
453	Phosphorylation	TVSSGYNTKKIGKRL CCCCCCCCCCHHHEE	25.82	28152594
468	Phosphorylation	NIQLKKGTEGLGFSI EEEECCCCCCCCEEE	35.44	20873877
474	Phosphorylation	GTEGLGFSITSRDVT CCCCCCEEEEECCEE	24.14	20873877
476	Phosphorylation	EGLGFSITSRDVTIG CCCCEEEEECCEEEC	19.26	23312004
477	Phosphorylation	GLGFSITSRDVTIGG CCCEEEEECCEEECC	25.47	27251275
481	Phosphorylation	SITSRDVTIGGSAPI EEEECCEEECCCCCE	20.42	22817900
485	Phosphorylation	RDVTIGGSAPIYVKN CCEEECCCCCEEEEE	26.17	21945579
489	Phosphorylation	IGGSAPIYVKNILPR ECCCCCEEEEECCCC	12.33	21945579
522 (in isoform 3)	Phosphorylation	-	41.30	29978859
522 (in isoform 5)	Phosphorylation	-	41.30	29978859
523	Phosphorylation	GVDLVGKSQEEVVSL CEECCCCCHHHHHHH	36.57	-
526 (in isoform 3)	Phosphorylation	-	40.35	28176443
526 (in isoform 5)	Phosphorylation	-	40.35	28176443
529	Phosphorylation	KSQEEVVSLLRSTKM CCHHHHHHHHHCCCC	27.19	-
533	Phosphorylation	EVVSLLRSTKMEGTV HHHHHHHCCCCCCEE	32.14	19664995
534	Phosphorylation	VVSLLRSTKMEGTVS HHHHHHCCCCCCEEE	28.16	19664995
561	Phosphorylation	RELNAEPSQMQIPKE CCCCCCHHHCCCCCC	29.77	29802988
566 (in isoform 11)	Phosphorylation	-	16.13	29978859
566 (in isoform 6)	Phosphorylation	-	16.13	29978859
566 (in isoform 7)	Phosphorylation	-	16.13	29978859
566 (in isoform 9)	Phosphorylation	-	16.13	29978859
570 (in isoform 11)	Phosphorylation	-	51.36	28176443
570 (in isoform 6)	Phosphorylation	-	51.36	28176443
570 (in isoform 7)	Phosphorylation	-	51.36	28176443
570 (in isoform 9)	Phosphorylation	-	51.36	28176443
575	Ubiquitination	ETKAEDEDIVLTPDG CCCCCCCCEEECCCC	48.93	32015554
579	Phosphorylation	EDEDIVLTPDGTREF CCCCEEECCCCCCEE	14.40	19664994
583	Phosphorylation	IVLTPDGTREFLTFE EEECCCCCCEEEEEE	34.11	29255136
596	Phosphorylation	FEVPLNDSGSAGLGV EEEECCCCCCCCCCE	33.31	-
598	Phosphorylation	VPLNDSGSAGLGVSV EECCCCCCCCCCEEE	24.10	-
604	Phosphorylation	GSAGLGVSVKGNRSK CCCCCCEEEECCCCC	19.13	-
619	Ubiquitination	ENHADLGIFVKSIIN CCCCCCEEEEHHHHC	4.69	32015554
632	Ubiquitination	INGGAASKDGRLRVN HCCCCCCCCCCCEEC	60.52	32015554
638	Phosphorylation	SKDGRLRVNDQLIAV CCCCCCEECCEEEEE	12.55	32142685
654	Phosphorylation	GESLLGKTNQDAMET HHHHCCCCCHHHHHH	35.99	30576142
654 (in isoform 11)	Phosphorylation	-	35.99	24719451
658	Phosphorylation	LGKTNQDAMETLRRS CCCCCHHHHHHHHHH	6.48	32142685
661	Phosphorylation	TNQDAMETLRRSMST CCHHHHHHHHHHHCC	16.69	30576142
665	Phosphorylation	AMETLRRSMSTEGNK HHHHHHHHHCCCCCH	15.62	-
667	Phosphorylation	ETLRRSMSTEGNKRG HHHHHHHCCCCCHHH	25.26	24719451
668	Phosphorylation	TLRRSMSTEGNKRGM HHHHHHCCCCCHHHH	38.99	28985074
671	Phosphorylation	RSMSTEGNKRGMIQL HHHCCCCCHHHHHHH	25.31	32142685
671 (in isoform 3)	Phosphorylation	-	25.31	25849741
671 (in isoform 5)	Phosphorylation	-	25.31	25849741
672	Acetylation	SMSTEGNKRGMIQLI HHCCCCCHHHHHHHH	62.27	19818727
679 (in isoform 11)	Phosphorylation	-	0.99	24719451
679 (in isoform 3)	Phosphorylation	-	0.99	22210691
679 (in isoform 5)	Phosphorylation	-	0.99	22210691
682	Phosphorylation	MIQLIVARRISKCNE HHHHHHHHHHHHCCC	26.10	32142685
682 (in isoform 11)	Phosphorylation	-	26.10	24719451
685	Phosphorylation	LIVARRISKCNELKS HHHHHHHHHCCCCCC	29.37	-
685 (in isoform 3)	Phosphorylation	-	29.37	30624053
685 (in isoform 5)	Phosphorylation	-	29.37	30624053
688 (in isoform 3)	Phosphorylation	-	62.46	30624053
688 (in isoform 5)	Phosphorylation	-	62.46	30624053
690 (in isoform 3)	Phosphorylation	-	4.07	30624053
690 (in isoform 5)	Phosphorylation	-	4.07	30624053
692	Phosphorylation	SKCNELKSPGSPPGP HHCCCCCCCCCCCCC	47.30	29255136
695	Phosphorylation	NELKSPGSPPGPELP CCCCCCCCCCCCCCC	31.16	29255136
698 (in isoform 3)	Phosphorylation	-	31.53	30624053
698 (in isoform 5)	Phosphorylation	-	31.53	30624053
702	Phosphorylation	SPPGPELPIETALDD CCCCCCCCCCHHCCH	22.25	32142685
702 (in isoform 11)	Phosphorylation	-	22.25	24719451
704 (in isoform 11)	Phosphorylation	-	26.53	24719451
705	Phosphorylation	GPELPIETALDDRER CCCCCCCHHCCHHHH	32.99	30576142
715	Phosphorylation	DDRERRISHSLYSGI CHHHHHHHHHHHHCC	12.76	23927012
715 (in isoform 11)	Phosphorylation	-	12.76	25849741
715 (in isoform 6)	Phosphorylation	-	12.76	25849741
715 (in isoform 7)	Phosphorylation	-	12.76	25849741
715 (in isoform 9)	Phosphorylation	-	12.76	25849741
717	Phosphorylation	RERRISHSLYSGIEG HHHHHHHHHHHCCCC	23.39	21945579
719	Phosphorylation	RRISHSLYSGIEGLD HHHHHHHHHCCCCCC	14.10	23927012
720	Phosphorylation	RISHSLYSGIEGLDE HHHHHHHHCCCCCCC	38.29	21945579
723 (in isoform 11)	Phosphorylation	-	58.17	22210691
723 (in isoform 6)	Phosphorylation	-	58.17	22210691
723 (in isoform 7)	Phosphorylation	-	58.17	22210691
723 (in isoform 9)	Phosphorylation	-	58.17	22210691
728	Phosphorylation	GIEGLDESPSRNAAL CCCCCCCCCCHHHHH	28.04	23927012
728 (in isoform 10)	Phosphorylation	-	28.04	25849741
728 (in isoform 2)	Phosphorylation	-	28.04	25849741
728 (in isoform 8)	Phosphorylation	-	28.04	25849741
729 (in isoform 11)	Phosphorylation	-	34.95	30624053
729 (in isoform 6)	Phosphorylation	-	34.95	30624053
729 (in isoform 7)	Phosphorylation	-	34.95	30624053
729 (in isoform 9)	Phosphorylation	-	34.95	30624053
730	Phosphorylation	EGLDESPSRNAALSR CCCCCCCCHHHHHHH	47.66	21945579
732 (in isoform 11)	Phosphorylation	-	33.62	30624053
732 (in isoform 6)	Phosphorylation	-	33.62	30624053
732 (in isoform 7)	Phosphorylation	-	33.62	30624053
732 (in isoform 9)	Phosphorylation	-	33.62	30624053
734 (in isoform 11)	Phosphorylation	-	15.04	30624053
734 (in isoform 6)	Phosphorylation	-	15.04	30624053
734 (in isoform 7)	Phosphorylation	-	15.04	30624053
734 (in isoform 9)	Phosphorylation	-	15.04	30624053
736	Phosphorylation	PSRNAALSRIMGESG CCHHHHHHHHHCCCC	18.29	24732914
736 (in isoform 10)	Phosphorylation	-	18.29	22210691
736 (in isoform 2)	Phosphorylation	-	18.29	22210691
736 (in isoform 8)	Phosphorylation	-	18.29	22210691
742 (in isoform 10)	Phosphorylation	-	34.55	30624053
742 (in isoform 11)	Phosphorylation	-	34.55	30624053
742 (in isoform 2)	Phosphorylation	-	34.55	30624053
742 (in isoform 6)	Phosphorylation	-	34.55	30624053
742 (in isoform 7)	Phosphorylation	-	34.55	30624053
742 (in isoform 8)	Phosphorylation	-	34.55	30624053
742 (in isoform 9)	Phosphorylation	-	34.55	30624053
745	Phosphorylation	IMGESGKYQLSPTVN HHCCCCCEEECCCCC	20.43	26471730
745 (in isoform 10)	Phosphorylation	-	20.43	30624053
745 (in isoform 2)	Phosphorylation	-	20.43	30624053
745 (in isoform 8)	Phosphorylation	-	20.43	30624053
747 (in isoform 10)	Phosphorylation	-	6.33	30624053
747 (in isoform 2)	Phosphorylation	-	6.33	30624053
747 (in isoform 8)	Phosphorylation	-	6.33	30624053
748	Phosphorylation	ESGKYQLSPTVNMPQ CCCCEEECCCCCCCC	11.73	26471730
749	Phosphorylation	SGKYQLSPTVNMPQD CCCEEECCCCCCCCC	49.29	32142685
750	Phosphorylation	GKYQLSPTVNMPQDD CCEEECCCCCCCCCC	22.57	26471730
755 (in isoform 10)	Phosphorylation	-	50.90	30624053
755 (in isoform 2)	Phosphorylation	-	50.90	30624053
755 (in isoform 8)	Phosphorylation	-	50.90	30624053
767	Phosphorylation	IIEDDRLPVLPPHLS EECCCCCCCCCCCCC	26.88	32645325
783 (in isoform 3)	Phosphorylation	-	54.99	24719451
785	Phosphorylation	SSSSHDDVGFVTADA CCCCCCCCEEEEECC	8.80	32142685
790 (in isoform 5)	Phosphorylation	-	10.19	26437602
791 (in isoform 11)	Phosphorylation	-	35.84	24719451
792 (in isoform 5)	Phosphorylation	-	18.17	25850435
793	Phosphorylation	GFVTADAGTWAKAAI EEEEECCCHHHHHHH	23.49	32142685
793 (in isoform 11)	Phosphorylation	-	23.49	24719451
795	Ubiquitination	VTADAGTWAKAAISD EEECCCHHHHHHHCC	8.54	32015554
797	Phosphorylation	ADAGTWAKAAISDSA ECCCHHHHHHHCCCC	29.88	32142685
797 (in isoform 5)	Phosphorylation	-	29.88	30177828
798 (in isoform 5)	Phosphorylation	-	11.41	30177828
800 (in isoform 5)	Phosphorylation	-	5.85	30177828
801	Phosphorylation	TWAKAAISDSADCSL HHHHHHHCCCCCCCC	22.30	22199227
803	Phosphorylation	AKAAISDSADCSLSP HHHHHCCCCCCCCCC	21.15	28102081
806	Phosphorylation	AISDSADCSLSPDVD HHCCCCCCCCCCCCC	4.39	32142685
807	Phosphorylation	ISDSADCSLSPDVDP HCCCCCCCCCCCCCH	32.22	22617229
809	Phosphorylation	DSADCSLSPDVDPVL CCCCCCCCCCCCHHH	11.62	25159151
810	Ubiquitination	SADCSLSPDVDPVLA CCCCCCCCCCCHHHH	51.44	32015554
811	Phosphorylation	ADCSLSPDVDPVLAF CCCCCCCCCCHHHHH	54.82	32645325
811 (in isoform 11)	Phosphorylation	-	54.82	24719451
812	Phosphorylation	DCSLSPDVDPVLAFQ CCCCCCCCCHHHHHH	11.56	32142685
821 (in isoform 11)	Phosphorylation	-	48.36	24719451
824	Phosphorylation	AFQREGFGRQSMSEK HHHCCCCCCCCCCHH	37.26	32645325
824 (in isoform 11)	Phosphorylation	-	37.26	24719451
827	Phosphorylation	REGFGRQSMSEKRTK CCCCCCCCCCHHHHH	23.94	30266825
827 (in isoform 6)	Phosphorylation	-	23.94	24719451
827 (in isoform 7)	Phosphorylation	-	23.94	24719451
827 (in isoform 9)	Phosphorylation	-	23.94	24719451
829	Phosphorylation	GFGRQSMSEKRTKQF CCCCCCCCHHHHHCC	45.25	23403867
833	Phosphorylation	QSMSEKRTKQFSDAS CCCCHHHHHCCCCHH	40.02	-
834	Acetylation	SMSEKRTKQFSDASQ CCCHHHHHCCCCHHH	54.07	-
836	Phosphorylation	SEKRTKQFSDASQLD CHHHHHCCCCHHHHH	8.33	32142685
837	Phosphorylation	EKRTKQFSDASQLDF HHHHHCCCCHHHHHH	29.76	30266825
839	Ubiquitination	RTKQFSDASQLDFVK HHHCCCCHHHHHHHH	9.66	32015554
840	Phosphorylation	TKQFSDASQLDFVKT HHCCCCHHHHHHHHC	35.95	30266825
841	Phosphorylation	KQFSDASQLDFVKTR HCCCCHHHHHHHHCC	46.93	32142685
847	Phosphorylation	SQLDFVKTRKSKSMD HHHHHHHCCCCCCCC	37.72	26074081
849	Phosphorylation	LDFVKTRKSKSMDLG HHHHHCCCCCCCCCC	68.42	32142685
850	Phosphorylation	DFVKTRKSKSMDLGI HHHHCCCCCCCCCCC	27.03	30266825
851	Acetylation	FVKTRKSKSMDLGIA HHHCCCCCCCCCCCC	53.48	-
851	Ubiquitination	FVKTRKSKSMDLGIA HHHCCCCCCCCCCCC	53.48	32015554
852	Phosphorylation	VKTRKSKSMDLGIAD HHCCCCCCCCCCCCC	25.31	19664994
853	Phosphorylation	KTRKSKSMDLGIADE HCCCCCCCCCCCCCC	5.91	32142685
854	Ubiquitination	TRKSKSMDLGIADET CCCCCCCCCCCCCCC	49.16	33845483
857 (in isoform 11)	Phosphorylation	-	5.93	24719451
859	Phosphorylation	SMDLGIADETKLNTV CCCCCCCCCCCCCCC	63.28	32142685
861	Phosphorylation	DLGIADETKLNTVDD CCCCCCCCCCCCCCC	41.18	23403867
865	Phosphorylation	ADETKLNTVDDQKAG CCCCCCCCCCCCCCC	35.43	26074081
867	Ubiquitination	ETKLNTVDDQKAGSP CCCCCCCCCCCCCCC	51.05	33845483
869	Ubiquitination	KLNTVDDQKAGSPSR CCCCCCCCCCCCCCC	32.79	32015554
870	Ubiquitination	LNTVDDQKAGSPSRD CCCCCCCCCCCCCCC	62.80	33845483
871	Phosphorylation	NTVDDQKAGSPSRDV CCCCCCCCCCCCCCC	20.33	32142685
871 (in isoform 11)	Phosphorylation	-	20.33	24719451
872	Phosphorylation	TVDDQKAGSPSRDVG CCCCCCCCCCCCCCC	47.31	32142685
872 (in isoform 11)	Phosphorylation	-	47.31	24719451
873	Phosphorylation	VDDQKAGSPSRDVGP CCCCCCCCCCCCCCH	25.27	23927012
875	Phosphorylation	DQKAGSPSRDVGPSL CCCCCCCCCCCCHHC	42.69	23927012
876 (in isoform 11)	Phosphorylation	-	46.12	24719451
881	Phosphorylation	PSRDVGPSLGLKKSS CCCCCCHHCCCCCCC	29.19	23927012
882	Ubiquitination	SRDVGPSLGLKKSSS CCCCCHHCCCCCCCC	11.95	32015554
884	Phosphorylation	DVGPSLGLKKSSSLE CCCHHCCCCCCCCHH	8.39	32142685
885	Acetylation	VGPSLGLKKSSSLES CCHHCCCCCCCCHHH	49.13	-
885	Ubiquitination	VGPSLGLKKSSSLES CCHHCCCCCCCCHHH	49.13	32015554
887	Phosphorylation	PSLGLKKSSSLESLQ HHCCCCCCCCHHHHH	24.46	27794612
888	Phosphorylation	SLGLKKSSSLESLQT HCCCCCCCCHHHHHH	48.07	30108239
889	Phosphorylation	LGLKKSSSLESLQTA CCCCCCCCHHHHHHH	43.16	27794612
892	Phosphorylation	KKSSSLESLQTAVAE CCCCCHHHHHHHEEE	30.94	28464451
895	Phosphorylation	SSLESLQTAVAEVTL CCHHHHHHHEEECCC	28.52	26699800
897	Ubiquitination	LESLQTAVAEVTLNG HHHHHHHEEECCCCC	5.46	24816145
901	Phosphorylation	QTAVAEVTLNGDIPF HHHEEECCCCCCCCC	13.15	23898821
908 (in isoform 11)	Phosphorylation	-	8.57	24719451
909	Ubiquitination	LNGDIPFHRPRPRII CCCCCCCCCCCCCEE	33.22	24816145
912	Ubiquitination	DIPFHRPRPRIIRGR CCCCCCCCCCEECCC	32.84	24816145
915	Acetylation	FHRPRPRIIRGRGCN CCCCCCCEECCCCCC	2.52	19608861
916	Phosphorylation	HRPRPRIIRGRGCNE CCCCCCEECCCCCCH	3.94	33259812
917	Acetylation	RPRPRIIRGRGCNES CCCCCEECCCCCCHH	26.78	19608861
924	Phosphorylation	RGRGCNESFRAAIDK CCCCCCHHHHHHHCC	13.17	30266825
928	Phosphorylation	CNESFRAAIDKSYDK CCHHHHHHHCCCCCC	13.27	33259812
929	Ubiquitination	NESFRAAIDKSYDKP CHHHHHHHCCCCCCC	7.18	24816145
930	Acetylation	ESFRAAIDKSYDKPA HHHHHHHCCCCCCCC	29.17	19608861
931	Ubiquitination	SFRAAIDKSYDKPAV HHHHHHCCCCCCCCC	44.81	24816145
931 (in isoform 11)	Phosphorylation	-	44.81	24719451
932	Acetylation	FRAAIDKSYDKPAVD HHHHHCCCCCCCCCC	34.51	19608861
932	Phosphorylation	FRAAIDKSYDKPAVD HHHHHCCCCCCCCCC	34.51	29496907
933	Phosphorylation	RAAIDKSYDKPAVDD HHHHCCCCCCCCCCC	33.45	27259358
940	Ubiquitination	YDKPAVDDDDEGMET CCCCCCCCCCCCCCC	59.67	24816145
941	Ubiquitination	DKPAVDDDDEGMETL CCCCCCCCCCCCCCH	51.93	24816145
942 (in isoform 11)	Phosphorylation	-	62.43	24719451
943	Ubiquitination	PAVDDDDEGMETLEE CCCCCCCCCCCCHHH	68.39	24816145
946	Phosphorylation	DDDDEGMETLEEDTE CCCCCCCCCHHHHCH	62.18	33259812
947	Phosphorylation	DDDEGMETLEEDTEE CCCCCCCCHHHHCHH	30.49	26657352
948 (in isoform 11)	Phosphorylation	-	4.29	24719451
952	Phosphorylation	METLEEDTEESSRSG CCCHHHHCHHHHHCC	44.95	27732954
953	Ubiquitination	ETLEEDTEESSRSGR CCHHHHCHHHHHCCC	69.10	24816145
954	Ubiquitination	TLEEDTEESSRSGRE CHHHHCHHHHHCCCC	56.99	24816145
955	Phosphorylation	LEEDTEESSRSGRES HHHHCHHHHHCCCCC	25.48	23909892
955 (in isoform 11)	Phosphorylation	-	25.48	24719451
956	Phosphorylation	EEDTEESSRSGRESV HHHCHHHHHCCCCCC	33.47	22210691
957	Ubiquitination	EDTEESSRSGRESVS HHCHHHHHCCCCCCC	53.03	24816145
957 (in isoform 11)	Phosphorylation	-	53.03	24719451
958	Phosphorylation	DTEESSRSGRESVST HCHHHHHCCCCCCCC	44.12	28348404
959	Acetylation	TEESSRSGRESVSTA CHHHHHCCCCCCCCC	35.94	19608861
959	Phosphorylation	TEESSRSGRESVSTA CHHHHHCCCCCCCCC	35.94	33259812
961	Acetylation	ESSRSGRESVSTASD HHHHCCCCCCCCCCC	60.04	19608861
962	Phosphorylation	SSRSGRESVSTASDQ HHHCCCCCCCCCCCC	21.73	25159151
964	Phosphorylation	RSGRESVSTASDQPS HCCCCCCCCCCCCCC	27.77	29255136
965	Phosphorylation	SGRESVSTASDQPSH CCCCCCCCCCCCCCH	28.20	23927012
967	Phosphorylation	RESVSTASDQPSHSL CCCCCCCCCCCCHHH	36.55	29255136
968	Ubiquitination	ESVSTASDQPSHSLE CCCCCCCCCCCHHHH	63.04	24816145
969	Ubiquitination	SVSTASDQPSHSLER CCCCCCCCCCHHHHH	38.61	24816145
970	Ubiquitination	VSTASDQPSHSLERQ CCCCCCCCCHHHHHH	38.71	24816145
971	Acetylation	STASDQPSHSLERQM CCCCCCCCHHHHHHH	21.78	19608861
971	Phosphorylation	STASDQPSHSLERQM CCCCCCCCHHHHHHH	21.78	30266825
971	Ubiquitination	STASDQPSHSLERQM CCCCCCCCHHHHHHH	21.78	24816145
972	Ubiquitination	TASDQPSHSLERQMN CCCCCCCHHHHHHHC	42.98	24816145
973	Acetylation	ASDQPSHSLERQMNG CCCCCCHHHHHHHCC	35.94	19608861
973	Phosphorylation	ASDQPSHSLERQMNG CCCCCCHHHHHHHCC	35.94	30266825
974	Ubiquitination	SDQPSHSLERQMNGN CCCCCHHHHHHHCCC	5.42	24816145
983	Ubiquitination	RQMNGNQEKGDKTDR HHHCCCCCCCCCCCH	64.11	24816145
984	Ubiquitination	QMNGNQEKGDKTDRK HHCCCCCCCCCCCHH	63.75	24816145
986	Ubiquitination	NGNQEKGDKTDRKKD CCCCCCCCCCCHHCC	62.85	24816145
987	Ubiquitination	GNQEKGDKTDRKKDK CCCCCCCCCCHHCCC	62.08	24816145
989	Acetylation	QEKGDKTDRKKDKTG CCCCCCCCHHCCCCC	67.17	19608861
991	Acetylation	KGDKTDRKKDKTGKE CCCCCCHHCCCCCHH	69.04	19608861
1002	Acetylation	TGKEKKKDRDKEKDK CCHHHCCHHHHHHHH	73.26	19608861
1004	Acetylation	KEKKKDRDKEKDKMK HHHCCHHHHHHHHHH	73.86	19608861
1005	Acetylation	EKKKDRDKEKDKMKA HHCCHHHHHHHHHHH	68.50	19608861
1007	Acetylation	KKDRDKEKDKMKAKK CCHHHHHHHHHHHHH	69.28	19608861
1013	Acetylation	EKDKMKAKKGMLKGL HHHHHHHHHHHHHHH	44.32	7708475
1014	Acetylation	KDKMKAKKGMLKGLG HHHHHHHHHHHHHHH	55.18	7708487
1030 (in isoform 11)	Phosphorylation	-	47.81	24719451
1046	Phosphorylation	GKIKIQESFTSEEER CCEEEEECCCCHHHH	19.90	25159151
1048	Phosphorylation	IKIQESFTSEEERIR EEEEECCCCHHHHHH	44.50	29978859
1049	Phosphorylation	KIQESFTSEEERIRM EEEECCCCHHHHHHH	40.79	29523821
1064 (in isoform 11)	Phosphorylation	-	42.92	24719451
1066	Phosphorylation	EQERIQAKTREFRER HHHHHHHHHHHHHHH	31.57	32142685
1080	Phosphorylation	RQARERDYAEIQDFH HHHHHHCHHHHHHHH	16.62	27273156
1088	Phosphorylation	AEIQDFHRTFGCDDE HHHHHHHHHHCCCCC	31.57	32142685
1095	Phosphorylation	RTFGCDDELMYGGVS HHHCCCCCCEECCCC	23.37	32142685
1098	Phosphorylation	GCDDELMYGGVSSYE CCCCCCEECCCCCCC	24.29	22817900
1100 (in isoform 11)	Phosphorylation	-	9.92	24719451
1102	Phosphorylation	ELMYGGVSSYEGSMA CCEECCCCCCCCCCC	30.40	28270605
1103	Phosphorylation	LMYGGVSSYEGSMAL CEECCCCCCCCCCCC	25.46	28270605
1104	Phosphorylation	MYGGVSSYEGSMALN EECCCCCCCCCCCCC	19.46	22817900
1107	Phosphorylation	GVSSYEGSMALNARP CCCCCCCCCCCCCCC	6.74	28270605
1111 (in isoform 11)	Phosphorylation	-	25.10	24719451
1116	Phosphorylation	ALNARPQSPREGHMM CCCCCCCCCCCCCHH	28.71	27422710
1127	Phosphorylation	GHMMDALYAQVKKPR CCHHHHHHHHCCCCC	9.19	21945579
1132	Phosphorylation	ALYAQVKKPRNSKPS HHHHHCCCCCCCCCC	50.80	32142685
1136	Phosphorylation	QVKKPRNSKPSPVDS HCCCCCCCCCCCCCC	47.42	29396449
1139	Phosphorylation	KPRNSKPSPVDSNRS CCCCCCCCCCCCCCC	41.09	30576142
1141	Phosphorylation	RNSKPSPVDSNRSTP CCCCCCCCCCCCCCC	17.27	32142685
1143	Phosphorylation	SKPSPVDSNRSTPSN CCCCCCCCCCCCCCC	34.08	30576142
1146	Phosphorylation	SPVDSNRSTPSNHDR CCCCCCCCCCCCHHH	49.25	30576142
1147	Phosphorylation	PVDSNRSTPSNHDRI CCCCCCCCCCCHHHH	27.74	30576142
1149	Phosphorylation	DSNRSTPSNHDRIQR CCCCCCCCCHHHHHH	47.05	30576142
1162	Phosphorylation	QRLRQEFQQAKQDED HHHHHHHHHHHCCCC	41.38	32142685
1162 (in isoform 11)	Phosphorylation	-	41.38	24719451
1175	Phosphorylation	EDVEDRRRTYSFEQP CCHHHHHHHCCCCCC	38.62	32142685
1176	Phosphorylation	DVEDRRRTYSFEQPW CHHHHHHHCCCCCCC	23.00	30266825
1177	Phosphorylation	VEDRRRTYSFEQPWP HHHHHHHCCCCCCCC	15.00	28796482
1178	Phosphorylation	EDRRRTYSFEQPWPN HHHHHHCCCCCCCCC	22.99	30266825
1196	Phosphorylation	ATQSGRHSVSVEVQM CCCCCCCEEEHHHHH	18.09	27732954
1198	Phosphorylation	QSGRHSVSVEVQMQR CCCCCEEEHHHHHHH	18.64	27422710
1206 (in isoform 11)	Phosphorylation	-	34.22	24719451
1221	Phosphorylation	SQQAQRQYSSLPRQS HHHHHHHHHHCCHHH	11.47	28796482
1222	Phosphorylation	QQAQRQYSSLPRQSR HHHHHHHHHCCHHHH	19.63	30266825
1223	Phosphorylation	QAQRQYSSLPRQSRK HHHHHHHHCCHHHHC	37.14	30266825
1233	Phosphorylation	RQSRKNASSVSQDSW HHHHCCCCCCCCCHH	40.44	27642862
1234	Phosphorylation	QSRKNASSVSQDSWE HHHCCCCCCCCCHHH	24.31	27642862
1236	Phosphorylation	RKNASSVSQDSWEQN HCCCCCCCCCHHHHC	30.16	21945579
1239	Phosphorylation	ASSVSQDSWEQNYSP CCCCCCCHHHHCCCC	25.52	21945579
1244	Phosphorylation	QDSWEQNYSPGEGFQ CCHHHHCCCCCCCCC	18.88	21945579
1244 (in isoform 11)	Phosphorylation	-	18.88	24719451
1245	Phosphorylation	DSWEQNYSPGEGFQS CHHHHCCCCCCCCCC	33.70	21945579
1252	Phosphorylation	SPGEGFQSAKENPRY CCCCCCCCCCCCCCC	38.76	29978859
1259	Phosphorylation	SAKENPRYSSYQGSR CCCCCCCCCCCCCCC	11.83	27259358
1260	Phosphorylation	AKENPRYSSYQGSRN CCCCCCCCCCCCCCC	24.69	27259358
1261	Phosphorylation	KENPRYSSYQGSRNG CCCCCCCCCCCCCCC	16.73	27259358
1262	Phosphorylation	ENPRYSSYQGSRNGY CCCCCCCCCCCCCCC	15.79	29449344
1265	Phosphorylation	RYSSYQGSRNGYLGG CCCCCCCCCCCCCCC	13.67	27259358
1269	Phosphorylation	YQGSRNGYLGGHGFN CCCCCCCCCCCCCCC	13.01	21945579
1308	Phosphorylation	QPPSEGPSNYDSYKK CCCCCCCCCHHHCCC	59.90	19060867
1310	Phosphorylation	PSEGPSNYDSYKKVQ CCCCCCCHHHCCCCC	15.59	27273156
1312	Phosphorylation	EGPSNYDSYKKVQDP CCCCCHHHCCCCCCC	28.61	26356563
1313	Phosphorylation	GPSNYDSYKKVQDPS CCCCHHHCCCCCCCC	16.36	27273156
1319 (in isoform 11)	Phosphorylation	-	16.49	24719451
1320	Phosphorylation	YKKVQDPSYAPPKGP CCCCCCCCCCCCCCC	42.06	21945579
1321	Phosphorylation	KKVQDPSYAPPKGPF CCCCCCCCCCCCCCC	28.63	21945579
1331 (in isoform 11)	Phosphorylation	-	51.11	24719451
1335	Phosphorylation	FRQDVPPSPSQVARL CCCCCCCCHHHHHHH	30.98	30266825
1337	Phosphorylation	QDVPPSPSQVARLNR CCCCCCHHHHHHHHC	41.44	30266825
1340 (in isoform 11)	Phosphorylation	-	11.56	24719451
1347	Phosphorylation	ARLNRLQTPEKGRPF HHHHCCCCCCCCCCC	37.70	29214152
1350	Acetylation	NRLQTPEKGRPFYS- HCCCCCCCCCCCCC-	62.51	-
1355	Phosphorylation	PEKGRPFYS------ CCCCCCCCC------	19.02	21712546
1356	Phosphorylation	EKGRPFYS------- CCCCCCCC-------	33.84	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
144	S	Phosphorylation	Kinase	MARK2	Q7KZI7	PSP
827	S	Phosphorylation	Kinase	PRKCI	P41743	GPS
873	S	Phosphorylation	Kinase	MARK2	Q7KZI7	PSP
962	S	Phosphorylation	Kinase	AURA	O14965	PSP
962	S	Phosphorylation	Kinase	AURKB	Q96GD4	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
827	S	Phosphorylation	23186163
Phosphorylation at Ser-827 by PRKCZ and PRKCI occurs at the most apical tip of epithelial cell-cell contacts during the initial phase of tight junction formation and may promote dissociation of the complex with PARD6.
962	S	Phosphorylation	19812038
Phosphorylation by AURKA at Ser-962 is required for the normal establishment of neuronal polarity.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PARD3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ECT2_HUMAN	ECT2	physical	15254234
JAM1_HUMAN	F11R	physical	12953056
JAM2_HUMAN	JAM2	physical	12953056
JAM3_HUMAN	JAM3	physical	12953056
PAR6A_HUMAN	PARD6A	physical	12459187
PAR6B_HUMAN	PARD6B	physical	12459187
PAR6G_HUMAN	PARD6G	physical	12459187
KPCI_HUMAN	PRKCI	physical	12459187
KPCZ_HUMAN	PRKCZ	physical	12459187
KPCI_HUMAN	PRKCI	physical	14676191
1433F_HUMAN	YWHAH	physical	14676191
DCAF7_HUMAN	DCAF7	physical	14676191
PNMA1_HUMAN	PNMA1	physical	14676191
RASF8_HUMAN	RASSF8	physical	14676191
PAR6B_HUMAN	PARD6B	physical	14676191
GRDN_HUMAN	CCDC88A	physical	14676191
PAR6G_HUMAN	PARD6G	physical	14676191
PNMA2_HUMAN	PNMA2	physical	14676191
L2GL1_HUMAN	LLGL1	physical	14676191
1433Z_HUMAN	YWHAZ	physical	14676191
HSP7C_HUMAN	HSPA8	physical	18685789
HSP76_HUMAN	HSPA6	physical	18685789
CH60_HUMAN	HSPD1	physical	18685789
PSME3_HUMAN	PSME3	physical	18685789
PSME2_HUMAN	PSME2	physical	18685789
RS3_HUMAN	RPS3	physical	18685789
RS18_HUMAN	RPS18	physical	18685789
PFKAP_HUMAN	PFKP	physical	18685789
IMA3_HUMAN	KPNA4	physical	18685789
AN32E_HUMAN	ANP32E	physical	18685789
ZO1_HUMAN	TJP1	physical	11257119
AMOT_HUMAN	AMOT	physical	16678097
GAB1_HUMAN	GAB1	physical	22883624
MARK2_HUMAN	MARK2	physical	22883624
KPCI_HUMAN	PRKCI	physical	22883624
PAR6A_HUMAN	PARD6A	physical	22883624
CTNB1_HUMAN	CTNNB1	physical	25241761
ASPP2_HUMAN	TP53BP2	physical	28400336

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PARD3_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1005, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-383; TYR-388; SER-728AND SER-852, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Phosphorylation of the par polarity complex protein Par3 at serine962 is mediated by aurora A and regulates its function in neuronalpolarity."; Khazaei M.R., Puschel A.W.; J. Biol. Chem. 284:33571-33579(2009). Cited for: INTERACTION WITH AURKA AND AURKB, FUNCTION, MUTAGENESIS OF SER-962,AND PHOSPHORYLATION AT SER-962.	19812038 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-174, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-383; SER-692; SER-695;SER-728; SER-809; SER-852 AND SER-873, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-143; SER-144; SER-383;SER-695; SER-715; SER-717 AND SER-728, AND MASS SPECTROMETRY.	18220336 [Abstract]
"Phosphoproteome of resting human platelets."; Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J.,Schuetz C., Walter U., Gambaryan S., Sickmann A.; J. Proteome Res. 7:526-534(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-852, AND MASSSPECTROMETRY.	18088087 [Abstract]
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-383, AND MASSSPECTROMETRY.	17924679 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-144, AND MASSSPECTROMETRY.	17081983 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-383, AND MASSSPECTROMETRY.	15302935 [Abstract]
"An extensive survey of tyrosine phosphorylation revealing new sitesin human mammary epithelial cells."; Heibeck T.H., Ding S.-J., Opresko L.K., Zhao R., Schepmoes A.A.,Yang F., Tolmachev A.V., Monroe M.E., Camp D.G. II, Smith R.D.,Wiley H.S., Qian W.-J.; J. Proteome Res. 8:3852-3861(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-388; TYR-489; TYR-719;TYR-1080 AND TYR-1127, AND MASS SPECTROMETRY.	19534553 [Abstract]
"Multiple reaction monitoring for robust quantitative proteomicanalysis of cellular signaling networks."; Wolf-Yadlin A., Hautaniemi S., Lauffenburger D.A., White F.M.; Proc. Natl. Acad. Sci. U.S.A. 104:5860-5865(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1080 AND TYR-1127, ANDMASS SPECTROMETRY.	17389395 [Abstract]
"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer."; Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.; Cell 131:1190-1203(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-489, AND MASSSPECTROMETRY.	18083107 [Abstract]
"Tyrosine phosphorylated Par3 regulates epithelial tight junctionassembly promoted by EGFR signaling."; Wang Y., Du D., Fang L., Yang G., Zhang C., Zeng R., Ullrich A.,Lottspeich F., Chen Z.; EMBO J. 25:5058-5070(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1127, MASS SPECTROMETRY,INTERACTION WITH LIMK2, AND MUTAGENESIS OF TYR-1127.	17053785 [Abstract]
"Time-resolved mass spectrometry of tyrosine phosphorylation sites inthe epidermal growth factor receptor signaling network reveals dynamicmodules."; Zhang Y., Wolf-Yadlin A., Ross P.L., Pappin D.J., Rush J.,Lauffenburger D.A., White F.M.; Mol. Cell. Proteomics 4:1240-1250(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1127, AND MASSSPECTROMETRY.	15951569 [Abstract]

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