| UniProt ID | PNMA1_HUMAN | |
|---|---|---|
| UniProt AC | Q8ND90 | |
| Protein Name | Paraneoplastic antigen Ma1 | |
| Gene Name | PNMA1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 353 | |
| Subcellular Localization | Nucleus, nucleolus . In tumor cells, it is cytoplasmic. | |
| Protein Description | ||
| Protein Sequence | MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEETLQAAMPQVSYRMLGRMFWREENAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDVARVLGFQNPTPTPGPEMPAEMLNYILDNVIQPLVESIWYKRLTLFSGRDIPGPGEETFDPWLEHTNEVLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDAQIKFLNTYQNPGEKLSAYVIRLEPLLQKVVEKGAIDKDNVNQARLEQVIAGANHSGAIRRQLWLTGAGEGPAPNLFQLLVQIREEEAKEEEEEAEATLLQLGLEGHF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 62 | Ubiquitination | FWREENAKAALLELT HHCHHHHHHHHHHHH | 45.86 | 21906983 | |
| 84 | Ubiquitination | IPREMPGKGGVWKVL CCCCCCCCCCEEEEE | 46.77 | 21906983 | |
| 89 | Ubiquitination | PGKGGVWKVLFKPPT CCCCCEEEEEECCCC | 27.01 | 22817900 | |
| 165 | Phosphorylation | YKRLTLFSGRDIPGP HHEEEEECCCCCCCC | 35.71 | 24719451 | |
| 198 | Ubiquitination | WQVSDVEKRRRLMES HCCCCHHHHHHHHHH | 51.56 | 29967540 | |
| 205 | Phosphorylation | KRRRLMESLRGPAAD HHHHHHHHHCCCHHH | 14.92 | 22673903 | |
| 218 | Ubiquitination | ADVIRILKSNNPAIT HHHHHHHHHCCCCCC | 49.09 | 23000965 | |
| 231 | Ubiquitination | ITTAECLKALEQVFG CCHHHHHHHHHHHHC | 63.68 | 21906983 | |
| 249 | Ubiquitination | SSRDAQIKFLNTYQN CCHHHHHEEEECCCC | 31.55 | 23000965 | |
| 249 | Ubiquitination | SSRDAQIKFLNTYQN CCHHHHHEEEECCCC | 31.55 | 21890473 | |
| 260 | Ubiquitination | TYQNPGEKLSAYVIR CCCCCCHHHEEEEHH | 54.37 | 23000965 | |
| 260 | Ubiquitination | TYQNPGEKLSAYVIR CCCCCCHHHEEEEHH | 54.37 | 21890473 | |
| 262 | Phosphorylation | QNPGEKLSAYVIRLE CCCCHHHEEEEHHHH | 28.73 | 24114839 | |
| 274 | Ubiquitination | RLEPLLQKVVEKGAI HHHHHHHHHHHCCCC | 48.49 | 21890473 | |
| 274 | Ubiquitination | RLEPLLQKVVEKGAI HHHHHHHHHHHCCCC | 48.49 | 23000965 | |
| 278 | Ubiquitination | LLQKVVEKGAIDKDN HHHHHHHCCCCCCCC | 41.87 | 23000965 | |
| 283 | Ubiquitination | VEKGAIDKDNVNQAR HHCCCCCCCCCCHHH | 45.12 | 21890473 | |
| 283 | Ubiquitination | VEKGAIDKDNVNQAR HHCCCCCCCCCCHHH | 45.12 | 23000965 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PNMA1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PNMA1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PNMA1_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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