RP25L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RP25L_HUMAN
• UniProt AC: Q8N5L8
• Protein Name: Ribonuclease P protein subunit p25-like protein
• Gene Name: RPP25L
• Organism: Homo sapiens (Human).
• Sequence Length: 163
• Subcellular Localization: Nucleus .
• Protein Description: May be a component of ribonuclease P or MRP..
• Protein Sequence: MEHYRKAGSVELPAPSPMPQLPPDTLEMRVRDGSKIRNLLGLALGRLEGGSARHVVFSGSGRAAGKAVSCAEIVKRRVPGLHQLTKLRFLQTEDSWVPASPDTGLDPLTVRRHVPAVWVLLSRDPLDPNECGYQPPGAPPGLGSMPSSSCGPRSRRRARDTRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MEHYRKAGSVE ----CCCCCCCCCCC	10.66	26074081
9	Phosphorylation	EHYRKAGSVELPAPS CCCCCCCCCCCCCCC	19.78	26074081
16	Phosphorylation	SVELPAPSPMPQLPP CCCCCCCCCCCCCCC	35.62	27050516
25	Phosphorylation	MPQLPPDTLEMRVRD CCCCCCCCEEEEECC	30.32	26074081
34	Phosphorylation	EMRVRDGSKIRNLLG EEEECCHHHHHHHHH	29.24	22210691
86	Ubiquitination	PGLHQLTKLRFLQTE CCHHHHCEEEEEECC	46.38	22817900
86	Acetylation	PGLHQLTKLRFLQTE CCHHHHCEEEEEECC	46.38	25953088
92	Phosphorylation	TKLRFLQTEDSWVPA CEEEEEECCCCCCCC	43.86	20068231
95	Phosphorylation	RFLQTEDSWVPASPD EEEECCCCCCCCCCC	24.60	20068231
100	Phosphorylation	EDSWVPASPDTGLDP CCCCCCCCCCCCCCC	19.76	22115753
103	Phosphorylation	WVPASPDTGLDPLTV CCCCCCCCCCCCCHH	42.92	20068231
109	Phosphorylation	DTGLDPLTVRRHVPA CCCCCCCHHHCCCCE	19.84	20068231
122	Phosphorylation	PAVWVLLSRDPLDPN CEEEEEEECCCCCCC	30.40	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RP25L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RP25L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RP25L_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of RP25L_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.