ZN581_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN581_HUMAN
• UniProt AC: Q9P0T4
• Protein Name: Zinc finger protein 581
• Gene Name: ZNF581
• Organism: Homo sapiens (Human).
• Sequence Length: 197
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MLVLPSPCPQPLAFSSVETMEGPPRRTCRSPEPGPSSSIGSPQASSPPRPNHYLLIDTQGVPYTVLVDEESQREPGASGAPGQKKCYSCPVCSRVFEYMSYLQRHSITHSEVKPFECDICGKAFKRASHLARHHSIHLAGGGRPHGCPLCPRRFRDAGELAQHSRVHSGERPFQCPHCPRRFMEQNTLQKHTRWKHP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MLVLPSPCPQPLA --CCCCCCCCCCCCC	34.67	24043423
15	Phosphorylation	CPQPLAFSSVETMEG CCCCCCCCCCCCCCC	28.06	24043423
16	Phosphorylation	PQPLAFSSVETMEGP CCCCCCCCCCCCCCC	19.95	24043423
19	Phosphorylation	LAFSSVETMEGPPRR CCCCCCCCCCCCCCC	20.54	24043423
30	Phosphorylation	PPRRTCRSPEPGPSS CCCCCCCCCCCCCCC	35.44	21406692
36	Phosphorylation	RSPEPGPSSSIGSPQ CCCCCCCCCCCCCCC	42.50	21406692
37	Phosphorylation	SPEPGPSSSIGSPQA CCCCCCCCCCCCCCC	29.16	21406692
38	Phosphorylation	PEPGPSSSIGSPQAS CCCCCCCCCCCCCCC	34.99	21406692
41	Phosphorylation	GPSSSIGSPQASSPP CCCCCCCCCCCCCCC	16.51	21406692
45	Phosphorylation	SIGSPQASSPPRPNH CCCCCCCCCCCCCCE	37.82	21406692
46	Phosphorylation	IGSPQASSPPRPNHY CCCCCCCCCCCCCEE	41.77	21406692
53	Phosphorylation	SPPRPNHYLLIDTQG CCCCCCEEEEEECCC	15.16	21406692
58	Phosphorylation	NHYLLIDTQGVPYTV CEEEEEECCCCEEEE	21.89	21406692
63	Phosphorylation	IDTQGVPYTVLVDEE EECCCCEEEEEECHH	13.69	21406692
64	Phosphorylation	DTQGVPYTVLVDEES ECCCCEEEEEECHHH	10.99	21406692
71	Phosphorylation	TVLVDEESQREPGAS EEEECHHHHCCCCCC	32.27	21406692
78	Phosphorylation	SQREPGASGAPGQKK HHCCCCCCCCCCCCC	41.21	21406692
108	Phosphorylation	YLQRHSITHSEVKPF HHHHCCCCCCCCCCE	23.51	28555341
110	Phosphorylation	QRHSITHSEVKPFEC HHCCCCCCCCCCEEC	35.12	28555341
168	Phosphorylation	AQHSRVHSGERPFQC HHHCCCCCCCCCCCC	39.22	29214152
183	Sulfoxidation	PHCPRRFMEQNTLQK CCCCHHHHHHCCCHH	4.99	21406390
190	Ubiquitination	MEQNTLQKHTRWKHP HHHCCCHHCCCCCCC	50.48	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN581_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN581_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN581_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LZTS2_HUMAN	LZTS2	physical	16189514
KR412_HUMAN	KRTAP4-12	physical	16189514
A4_HUMAN	APP	physical	21832049
KDM1A_HUMAN	KDM1A	physical	23455924
SUV91_HUMAN	SUV39H1	physical	23455924
BANP_HUMAN	BANP	physical	25416956
GOPC_HUMAN	GOPC	physical	25416956
CC136_HUMAN	CCDC136	physical	25416956
HMBX1_HUMAN	HMBOX1	physical	25416956
DOCK8_HUMAN	DOCK8	physical	25416956
KR412_HUMAN	KRTAP4-12	physical	25416956
LZTS2_HUMAN	LZTS2	physical	25416956
LNX1_HUMAN	LNX1	physical	25416956
KRA42_HUMAN	KRTAP4-2	physical	25416956
FSD2_HUMAN	FSD2	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
SPERT_HUMAN	SPERT	physical	25416956
KR107_HUMAN	KRTAP10-7	physical	25416956
KR109_HUMAN	KRTAP10-9	physical	25416956
KR101_HUMAN	KRTAP10-1	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956
NT2NL_HUMAN	NOTCH2NL	physical	25416956
ADNP_HUMAN	ADNP	physical	28514442
DIRA2_HUMAN	DIRAS2	physical	28514442
HIKES_HUMAN	C11orf73	physical	28514442
CHD4_HUMAN	CHD4	physical	28514442
ERBIN_HUMAN	ERBB2IP	physical	28514442
DMWD_HUMAN	DMWD	physical	28514442
NT5C_HUMAN	NT5C	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.