PNMA2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PNMA2_HUMAN
• UniProt AC: Q9UL42
• Protein Name: Paraneoplastic antigen Ma2
• Gene Name: PNMA2
• Organism: Homo sapiens (Human).
• Sequence Length: 364
• Subcellular Localization: Nucleus, nucleolus .
• Protein Sequence: MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEEASFENESIEEPEERDGYGRWNHEGDD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MALALLEDW ------CHHHHHHHH	11.09	-
54	Ubiquitination	GRYRLLGKIFRKQEN CHHHHHHHHHHCHHC	38.34	21890473
54	Ubiquitination	GRYRLLGKIFRKQEN CHHHHHHHHHHCHHC	38.34	21890473
58	Ubiquitination	LLGKIFRKQENANAV HHHHHHHCHHCCCHH	51.74	-
85	Ubiquitination	IPSEVQGKGGVWKVI CCHHHCCCCCEEEEE	35.09	-
94	Ubiquitination	GVWKVIFKTPNQDTE CEEEEEEECCCCCHH	52.53	-
112	Ubiquitination	RLNLFLEKEGQTVSG HHHHHHHHCCCCHHH	70.10	-
118	Phosphorylation	EKEGQTVSGMFRALG HHCCCCHHHHHHHHC	28.11	22199227
256	Ubiquitination	TAQVRYLKTYQEEGE HHHHEEEEHHHHHCC	35.93	21890473
256	Ubiquitination	TAQVRYLKTYQEEGE HHHHEEEEHHHHHCC	35.93	21890473
264	Ubiquitination	TYQEEGEKVSAYVLR HHHHHCCHHHHHHHH	52.96	-
274	Phosphorylation	AYVLRLETLLRRAVE HHHHHHHHHHHHHHH	35.37	23312004
316	Ubiquitination	WCRLRELKDQGPPPS HHHHHHHHHCCCCCC	43.16	21890473
316	Ubiquitination	WCRLRELKDQGPPPS HHHHHHHHHCCCCCC	43.16	21890473
323	Phosphorylation	KDQGPPPSFLELMKV HHCCCCCCHHHHHHH	48.51	-
329	Ubiquitination	PSFLELMKVIREEEE CCHHHHHHHHHHHHH	47.32	21890473
329	Ubiquitination	PSFLELMKVIREEEE CCHHHHHHHHHHHHH	47.32	21890473
340	Phosphorylation	EEEEEEASFENESIE HHHHHHHCCCCCCCC	36.05	26471730
345	Phosphorylation	EASFENESIEEPEER HHCCCCCCCCCCHHC	47.05	22912867
355	Phosphorylation	EPEERDGYGRWNHEG CCHHCCCCCCCCCCC	14.06	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PNMA2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PNMA2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PNMA2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
C43BP_HUMAN	COL4A3BP	physical	22863883
PRP31_HUMAN	PRPF31	physical	25416956
CBX8_HUMAN	CBX8	physical	25416956
SCNM1_HUMAN	SCNM1	physical	25416956
CCD33_HUMAN	CCDC33	physical	25416956
ENKD1_HUMAN	ENKD1	physical	25416956
F161A_HUMAN	FAM161A	physical	25416956
ZN587_HUMAN	ZNF587	physical	25416956
LLR1_HUMAN	LRR1	physical	25416956
ZN417_HUMAN	ZNF417	physical	25416956
TTL10_HUMAN	TTLL10	physical	25416956
RTP5_HUMAN	RTP5	physical	25416956
ZN417_HUMAN	ZNF417	physical	21516116
ENKD1_HUMAN	ENKD1	physical	21516116
RNF8_HUMAN	RNF8	physical	21516116

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.