S2548_HUMAN - dbPTM
S2548_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID S2548_HUMAN
UniProt AC Q6ZT89
Protein Name Solute carrier family 25 member 48
Gene Name SLC25A48
Organism Homo sapiens (Human).
Sequence Length 311
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein.
Protein Description
Protein Sequence MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQTQPFRDANLGLKSRAVAPAEQPAYQGPVHCITTIVRNEGLAGLYRGASAMLLRDVPGYCLYFIPYVFLSEWITPEACTGPSPCAVWLAGGMAGAISWGTATPMDVVKSRLQADGVYLNKYKGVLDCISQSYQKEGLKVFFRGITVNAVRGFPMSAAMFLGYELSLQAIRGDHAVTSP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
44PhosphorylationVGYGNTLSCIRVVYR
CCCCCHHHHEEEEEE
12.8824719451
102 (in isoform 3)Phosphorylation-36.0722210691
104 (in isoform 3)Phosphorylation-26.1222210691
110 (in isoform 3)Phosphorylation-17.4822210691
117 (in isoform 3)Phosphorylation-14.20-
117PhosphorylationSMVAGVVSVGLGGPV
HHHHHHHHCCCCCCH
14.20-
242PhosphorylationTPMDVVKSRLQADGV
CHHHHHHHHHHCCCE
26.9830266825
250PhosphorylationRLQADGVYLNKYKGV
HHHCCCEEECCCCCH
15.3030266825
254PhosphorylationDGVYLNKYKGVLDCI
CCEEECCCCCHHHHH
16.3530266825

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of S2548_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of S2548_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of S2548_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KR107_HUMANKRTAP10-7physical
25416956
KR103_HUMANKRTAP10-3physical
25416956
TPM2_HUMANTPM2physical
28514442
RNF11_HUMANRNF11physical
28514442
EF2_HUMANEEF2physical
28514442
ANR40_HUMANANKRD40physical
28514442

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of S2548_HUMAN

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Related Literatures of Post-Translational Modification

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