PNM6A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PNM6A_HUMAN
• UniProt AC: P0CW24
• Protein Name: Paraneoplastic antigen-like protein 6A {ECO:0000305}
• Gene Name: PNMA6A {ECO:0000312|HGNC:HGNC:28248}
• Organism: Homo sapiens (Human).
• Sequence Length: 399
• Protein Sequence: MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKAFREEDNATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVESVAGALGVGLRRVCWLRSIGQAVQPWVEAVRCQSLGVFSGRDQPAPGEESFEVWLDHTTEMLHVWQGVSERERRRRLLEGLRGTALQLVHALLAENPARTAQDCLAALAQVFGDNESQATIRVKCLTAQQQSGERLSAFVLRLEVLLQKAMEKEALARASADRVRLRQMLTRAHLTEPLDEALRKLRMAGRSPSFLEMLGLVRESEAWEASLARSVRAQTQEGAGARAGAQAVARASTKVEAVPGGPGREPEGLLQAGGQEAEELLQEGLKPVLEECDN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	LRPMGHFTVLGKAFR HHHHCEEEEECHHHH	14.78	25690035
170	Phosphorylation	QPAPGEESFEVWLDH CCCCCCCCEEEEHHC	23.54	-
244	Ubiquitination	SQATIRVKCLTAQQQ CCEEEEEEEEECCHH	17.43	-
269	Ubiquitination	RLEVLLQKAMEKEAL HHHHHHHHHHHHHHH	50.06	-
273	Ubiquitination	LLQKAMEKEALARAS HHHHHHHHHHHHHHC	34.89	-
280	Phosphorylation	KEALARASADRVRLR HHHHHHHCCHHHHHH	25.75	27251275
291	Phosphorylation	VRLRQMLTRAHLTEP HHHHHHHHHHHCCCC	22.07	27251275
325	Phosphorylation	MLGLVRESEAWEASL HHCCCCCHHHHHHHH	23.27	24719451
331	Phosphorylation	ESEAWEASLARSVRA CHHHHHHHHHHHHHH	15.85	30624053
335	Phosphorylation	WEASLARSVRAQTQE HHHHHHHHHHHHHHC	15.45	30624053
340	Phosphorylation	ARSVRAQTQEGAGAR HHHHHHHHHCCCHHH	27.83	30624053
359	Ubiquitination	AVARASTKVEAVPGG HHHHHCCCEEECCCC	35.27	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PNM6A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PNM6A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PNM6A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PNMA1_HUMAN	PNMA1	physical	16169070

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.