RSPH9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RSPH9_HUMAN
• UniProt AC: Q9H1X1
• Protein Name: Radial spoke head protein 9 homolog
• Gene Name: RSPH9
• Organism: Homo sapiens (Human).
• Sequence Length: 276
• Subcellular Localization: Cytoplasm, cytoskeleton, cilium axoneme . Radial spoke.
• Protein Description: Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules..
• Protein Sequence: MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIAQGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVNEGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSEAKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQMERGNALVVLRSLLWPGLTFYHAPRTKNYGYVYVGTGEKNMDLPFML

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Phosphorylation	LSPDRRASLLTSLML CCHHHHHHHHHHHHH	23.31	-
30	Phosphorylation	DRRASLLTSLMLVKR HHHHHHHHHHHHHHC	25.71	-
89	Phosphorylation	WSLLPPATEEMVAQS CCCCCCCCHHHHHCC	37.95	-
97	Phosphorylation	EEMVAQSSVVKGRFM HHHHHCCCCCCCCCC	20.89	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RSPH9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RSPH9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RSPH9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZC3H4_HUMAN	ZC3H4	physical	26186194
BCR_HUMAN	BCR	physical	26186194
SAFB2_HUMAN	SAFB2	physical	26186194
MOCS3_HUMAN	MOCS3	physical	26186194
EIF3A_HUMAN	EIF3A	physical	26186194
EIF3C_HUMAN	EIF3C	physical	26186194
EIF3H_HUMAN	EIF3H	physical	26186194
LONP2_HUMAN	LONP2	physical	26186194
EIF3B_HUMAN	EIF3B	physical	26186194
EIF3E_HUMAN	EIF3E	physical	26186194
PP1RA_HUMAN	PPP1R10	physical	26186194
ZC3H4_HUMAN	ZC3H4	physical	28514442
LONP2_HUMAN	LONP2	physical	28514442
BCR_HUMAN	BCR	physical	28514442
PP1RA_HUMAN	PPP1R10	physical	28514442
EIF3H_HUMAN	EIF3H	physical	28514442
EIF3A_HUMAN	EIF3A	physical	28514442
MOCS3_HUMAN	MOCS3	physical	28514442
EIF3C_HUMAN	EIF3C	physical	28514442
EIF3B_HUMAN	EIF3B	physical	28514442
EIF3E_HUMAN	EIF3E	physical	28514442
LONP2_HUMAN	LONP2	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.