TTC9C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TTC9C_HUMAN
• UniProt AC: Q8N5M4
• Protein Name: Tetratricopeptide repeat protein 9C
• Gene Name: TTC9C
• Organism: Homo sapiens (Human).
• Sequence Length: 171
• Protein Sequence: MEKRLQEAQLYKEEGNQRYREGKYRDAVSRYHRALLQLRGLDPSLPSPLPNLGPQGPALTPEQENILHTTQTDCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDQARHYLLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQLYLGMFG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Ubiquitination	LQEAQLYKEEGNQRY HHHHHHHHHHHCHHH	58.86	21906983
12	Acetylation	LQEAQLYKEEGNQRY HHHHHHHHHHHCHHH	58.86	25953088
25	Ubiquitination	RYREGKYRDAVSRYH HHHCCHHHHHHHHHH	28.97	24816145
56	Ubiquitination	LPNLGPQGPALTPEQ CCCCCCCCCCCCHHH	16.75	24816145
99	Ubiquitination	RVREYSQKVLERQPD HHHHHHHHHHHHCCC	42.73	-
99	Acetylation	RVREYSQKVLERQPD HHHHHHHHHHHHCCC	42.73	27452117
109	Ubiquitination	ERQPDNAKALYRAGV HHCCCCHHHHHHCCE	45.22	24816145
140	Ubiquitination	AAVNRQPKDANVRRY HHHHCCCCCCCHHHH	62.22	24816145
147	Phosphorylation	KDANVRRYLQLTQSE CCCCHHHHHHCHHHH	6.55	-
156	Phosphorylation	QLTQSELSSYHRKEK HCHHHHHHHHHHHHC	25.46	28796482
157	Phosphorylation	LTQSELSSYHRKEKQ CHHHHHHHHHHHHCH	37.27	28796482
158	Phosphorylation	TQSELSSYHRKEKQL HHHHHHHHHHHHCHH	11.41	28796482
166	Phosphorylation	HRKEKQLYLGMFG-- HHHHCHHHHHCCC--	9.94	27642862

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TTC9C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TTC9C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TTC9C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBE4B_HUMAN	UBE4B	physical	22939629
UBE2C_HUMAN	UBE2C	physical	22939629
UBL7_HUMAN	UBL7	physical	22939629
UFC1_HUMAN	UFC1	physical	22939629
UB2V1_HUMAN	UBE2V1	physical	22939629
VPS4B_HUMAN	VPS4B	physical	22939629
TTL12_HUMAN	TTLL12	physical	22939629
UBQL4_HUMAN	UBQLN4	physical	22939629
UCHL3_HUMAN	UCHL3	physical	22939629
ANCHR_HUMAN	ZFYVE19	physical	22939629
ZRAB2_HUMAN	ZRANB2	physical	22939629
YAP1_HUMAN	YAP1	physical	22939629
UB2V2_HUMAN	UBE2V2	physical	22939629

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.