SCND1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCND1_HUMAN
• UniProt AC: P57086
• Protein Name: SCAN domain-containing protein 1
• Gene Name: SCAND1
• Organism: Homo sapiens (Human).
• Sequence Length: 179
• Subcellular Localization: Nucleus .
• Protein Description: May regulate transcriptional activity..
• Protein Sequence: MAATEPILAATGSPAAVPPEKLEGAGSSSAPERNCVGSSLPEASPPAPEPSSPNAAVPEAIPTPRAAASAALELPLGPAPVSVAPQAEAEARSTPGPAGSRLGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLLAILPEAARARRIRRRTDVRITG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	TEPILAATGSPAAVP CCCCHHHCCCCCCCC	32.36	22199227
13	Phosphorylation	PILAATGSPAAVPPE CCHHHCCCCCCCCHH	13.65	25849741
27	Phosphorylation	EKLEGAGSSSAPERN HHCCCCCCCCCCCCC	22.15	26852163
28	Phosphorylation	KLEGAGSSSAPERNC HCCCCCCCCCCCCCC	29.60	26852163
29	Phosphorylation	LEGAGSSSAPERNCV CCCCCCCCCCCCCCC	49.92	26852163
39	Phosphorylation	ERNCVGSSLPEASPP CCCCCCCCCCCCCCC	41.85	26074081
44	Phosphorylation	GSSLPEASPPAPEPS CCCCCCCCCCCCCCC	29.74	28450419
51	Phosphorylation	SPPAPEPSSPNAAVP CCCCCCCCCCCCCCC	57.68	25627689
52	Phosphorylation	PPAPEPSSPNAAVPE CCCCCCCCCCCCCCC	32.65	25159151
63	Phosphorylation	AVPEAIPTPRAAASA CCCCCCCCHHHHHHH	21.20	28450419
69	Phosphorylation	PTPRAAASAALELPL CCHHHHHHHHHCCCC	14.89	20058876
115	Phosphorylation	RQRFRQFRYQDAAGP HHHHHHHHHHCCCCH	21.62	27251275
116	Phosphorylation	QRFRQFRYQDAAGPR HHHHHHHHHCCCCHH	16.42	-
144	Ubiquitination	LRPDIRTKEQIVEML HCCCCCCHHHHHHHH	37.46	-
173	Phosphorylation	ARRIRRRTDVRITG- HHHHHHHCCCCCCC-	36.71	22817900
178	Phosphorylation	RRTDVRITG------ HHCCCCCCC------	26.69	21712546

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCND1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCND1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCND1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZSC32_HUMAN	ZSCAN32	physical	16189514
ZKSC7_HUMAN	ZKSCAN7	physical	16189514
ZN397_HUMAN	ZNF397	physical	20211142
ZKSC7_HUMAN	ZKSCAN7	physical	25416956
PGBD1_HUMAN	PGBD1	physical	25416956
ZN449_HUMAN	ZNF449	physical	25416956
ZKSC4_HUMAN	ZKSCAN4	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.