SHSA3_HUMAN - dbPTM
SHSA3_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SHSA3_HUMAN
UniProt AC A0PJX4
Protein Name Protein shisa-3 homolog
Gene Name SHISA3
Organism Homo sapiens (Human).
Sequence Length 238
Subcellular Localization Endoplasmic reticulum membrane
Single-pass type I membrane protein .
Protein Description Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling..
Protein Sequence MRALLALCLLLGWLRWGPAGAQQSGEYCHGWVDVQGNYHEGFQCPEDFDTLDATICCGSCALRYCCAAADARLEQGGCTNDRRELEHPGITAQPVYVPFLIVGSIFIAFIILGSVVAIYCCTCLRPKEPSQQPIRFSLRSYQTETLPMILTSTSPRAPSRQSSTATSSSSTGGSIRRFSFARAEPGCLVPSPPPPYTTSHSIHLAQPSGFLVSPQYFAYPLQQEPPLPGKSCPDFSSS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
91PhosphorylationELEHPGITAQPVYVP
HCCCCCCCCCCCCCC
25.7522210691
104PhosphorylationVPFLIVGSIFIAFII
CCHHHHHHHHHHHHH
11.9322210691
119PhosphorylationLGSVVAIYCCTCLRP
HHHHHHHHHHHHCCC
3.3222210691
137PhosphorylationSQQPIRFSLRSYQTE
CCCCCEEEEEECCCC
17.0226657352
140PhosphorylationPIRFSLRSYQTETLP
CCEEEEEECCCCCCC
27.2127732954
141PhosphorylationIRFSLRSYQTETLPM
CEEEEEECCCCCCCE
17.0226657352
143PhosphorylationFSLRSYQTETLPMIL
EEEEECCCCCCCEEE
23.7827732954
145PhosphorylationLRSYQTETLPMILTS
EEECCCCCCCEEEEE
39.2827732954
151PhosphorylationETLPMILTSTSPRAP
CCCCEEEEECCCCCC
21.0227732954
152PhosphorylationTLPMILTSTSPRAPS
CCCEEEEECCCCCCC
24.3627732954
153PhosphorylationLPMILTSTSPRAPSR
CCEEEEECCCCCCCC
37.2027732954
154PhosphorylationPMILTSTSPRAPSRQ
CEEEEECCCCCCCCC
16.5028857561
159PhosphorylationSTSPRAPSRQSSTAT
ECCCCCCCCCCCCCC
41.80-
162PhosphorylationPRAPSRQSSTATSSS
CCCCCCCCCCCCCCC
28.66-
169PhosphorylationSSTATSSSSTGGSIR
CCCCCCCCCCCCCEE
31.52-
174PhosphorylationSSSSTGGSIRRFSFA
CCCCCCCCEEEEEEE
17.8024114839
179PhosphorylationGGSIRRFSFARAEPG
CCCEEEEEEEECCCC
19.0424702127
216PhosphorylationGFLVSPQYFAYPLQQ
CEEECCHHEEEECCC
8.12-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SHSA3_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SHSA3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SHSA3_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of SHSA3_HUMAN !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SHSA3_HUMAN

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Related Literatures of Post-Translational Modification

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