MB212_HUMAN - dbPTM
MB212_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MB212_HUMAN
UniProt AC Q9Y586
Protein Name Protein mab-21-like 2
Gene Name MAB21L2
Organism Homo sapiens (Human).
Sequence Length 359
Subcellular Localization Nucleus . Cytoplasm . Predominantly localizes to the nucleus, with some cytoplasmic localization (PubMed:25719200).
Protein Description Required for several aspects of embryonic development including normal development of the eye..
Protein Sequence MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationAAQAKLVYQLNKYYT
HHHHHHHHHHHHHHH		20.0922817900
15PhosphorylationLVYQLNKYYTERCQA
HHHHHHHHHHHHHHH		17.9722817900
16PhosphorylationVYQLNKYYTERCQAR
HHHHHHHHHHHHHHH		12.0622817900
39PhosphorylationREVCKVVSDVLKEVE
HHHHHHHHHHHHHCC		25.6224719451
109PhosphorylationLSDGRKRSMSLWVEF
CCCCCCEEHHHHHHH		18.76-
130PhosphorylationLSARKIRSRFQTLVA
HHHHHHHHHHHHHHH		40.70-
134PhosphorylationKIRSRFQTLVAQAVD
HHHHHHHHHHHHHHH		22.08-
144PhosphorylationAQAVDKCSYRDVVKM
HHHHHHCCHHHHHHH		29.0122798277
145PhosphorylationQAVDKCSYRDVVKMI
HHHHHCCHHHHHHHH		21.9422798277
204UbiquitinationPNRVAEVKAEGFNLL
CCCEEEHHHHCCCCH		32.0232142685
252PhosphorylationGCRNKCLSVLKTLRD
HHHHHHHHHHHHHHH		34.57-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MB212_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MB212_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MB212_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
A4_HUMANAPPphysical
21832049
C102B_HUMANCCDC102Bphysical
25416956
K1C40_HUMANKRT40physical
25416956
AINX_HUMANINAphysical
26186194
MEIS1_HUMANMEIS1physical
26186194
MEIS2_HUMANMEIS2physical
26186194
PBX1_HUMANPBX1physical
26186194
PBX2_HUMANPBX2physical
26186194
PBX3_HUMANPBX3physical
26186194
MID51_HUMANMIEF1physical
26186194
EDRF1_HUMANEDRF1physical
26186194
PNMA1_HUMANPNMA1physical
21516116
MEIS2_HUMANMEIS2physical
28514442
MEIS1_HUMANMEIS1physical
28514442
MID51_HUMANMIEF1physical
28514442
PBX3_HUMANPBX3physical
28514442
PBX2_HUMANPBX2physical
28514442
PBX1_HUMANPBX1physical
28514442
AINX_HUMANINAphysical
28514442
EDRF1_HUMANEDRF1physical
28514442
BACD3_HUMANKCTD10physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
615877Microphthalmia, syndromic, 14 (MCOPS14)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MB212_HUMAN

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Related Literatures of Post-Translational Modification

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