TRI42_HUMAN - dbPTM
TRI42_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TRI42_HUMAN
UniProt AC Q8IWZ5
Protein Name Tripartite motif-containing protein 42
Gene Name TRIM42
Organism Homo sapiens (Human).
Sequence Length 723
Subcellular Localization
Protein Description
Protein Sequence METAMCVCCPCCTWQRCCPQLCSCLCCKFIFTSERNCTCFPCPYKDERNCQFCHCTCSESPNCHWCCCSWANDPNCKCCCTASSNLNCYYYESRCCRNTIITFHKGRLRSIHTSSKTALRTGSSDTQVDEVKSIPANSHLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNKRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLHSINYVPLDFVELSSAIHELFPTGPKKVRSSGDSLPSPYPVHSETMIARKVTFSTHSLGNQHIYQRSSSMLSFSNTDKKAKVGLEACGRAQSATPAKPTDGLYTYWSAGADSQSVQNSSSFHNWYSFNDGSVKTPGPIVIYQTLVYPRAAKVYWTCPAEDVDSFEMEFYEVITSPPNNVQMELCGQIRDIMQQNLELHNLTPNTEYVFKVRAINDNGPGQWSDICKVVTPDGHGKNRAKWGLLKNIQSALQKHF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
110PhosphorylationFHKGRLRSIHTSSKT
EECCCEEECCCCCCH		24.2630622161
113PhosphorylationGRLRSIHTSSKTALR
CCEEECCCCCCHHHH		32.7830622161
114PhosphorylationRLRSIHTSSKTALRT
CEEECCCCCCHHHHC		18.7030622161
115PhosphorylationLRSIHTSSKTALRTG
EEECCCCCCHHHHCC		34.8730622161
117PhosphorylationSIHTSSKTALRTGSS
ECCCCCCHHHHCCCC		32.6430622161
121PhosphorylationSSKTALRTGSSDTQV
CCCHHHHCCCCCCCC		42.1230622161
123PhosphorylationKTALRTGSSDTQVDE
CHHHHCCCCCCCCCC		25.1630622161
124PhosphorylationTALRTGSSDTQVDEV
HHHHCCCCCCCCCCC		46.1230622161
126PhosphorylationLRTGSSDTQVDEVKS
HHCCCCCCCCCCCCC		32.2330622161
194PhosphorylationICPVCDRSHCMPYSN
EEECCCCHHCCCCCC		14.0522468782
200PhosphorylationRSHCMPYSNKMQLPE
CHHCCCCCCCCCCCC		24.8922468782
232PhosphorylationLKWRFDRSSGPILCQ
EEEEECCCCCCEEHH		41.3028842319
233PhosphorylationKWRFDRSSGPILCQV
EEEECCCCCCEEHHH		49.8628842319
301PhosphorylationPSSRIIEYCRNDNKL
CCHHHHHHHCCCCCE		6.0622817900
349PhosphorylationAKFKAVRYEIDNDLM
HHHHHHEEEECCCHH		15.61-
364PhosphorylationEFNILKNSFKADKEA
HHHHHHHCHHCCHHH		26.91-
385PhosphorylationNGFLKLRSILQEKEK
HHHHHHHHHHHHHHH		37.7822210691
412PhosphorylationRQKEIEKYVYVTTMK
CHHHHHEEEEEEEEE		5.57-
414PhosphorylationKEIEKYVYVTTMKVN
HHHHEEEEEEEEECC		6.76-
416PhosphorylationIEKYVYVTTMKVNEM
HHEEEEEEEEECCCC		11.95-
417PhosphorylationEKYVYVTTMKVNEMD
HEEEEEEEEECCCCC		12.64-
429PhosphorylationEMDGLIAYSKEALKE
CCCCEEEECHHHHHH		17.1826307563
430PhosphorylationMDGLIAYSKEALKET
CCCEEEECHHHHHHH		18.2626307563
499PhosphorylationTGPKKVRSSGDSLPS
CCCCCCCCCCCCCCC		41.4824719451
500PhosphorylationGPKKVRSSGDSLPSP
CCCCCCCCCCCCCCC		35.7325693802
503PhosphorylationKVRSSGDSLPSPYPV
CCCCCCCCCCCCCCC		45.7825693802
506PhosphorylationSSGDSLPSPYPVHSE
CCCCCCCCCCCCCCC		42.2124719451
508PhosphorylationGDSLPSPYPVHSETM
CCCCCCCCCCCCCCE		23.4025693802
512PhosphorylationPSPYPVHSETMIARK
CCCCCCCCCCEEEEE		34.6924719451
514PhosphorylationPYPVHSETMIARKVT
CCCCCCCCEEEEEEE		19.5225693802
521PhosphorylationTMIARKVTFSTHSLG
CEEEEEEEEECCCCC		18.2030622161
523PhosphorylationIARKVTFSTHSLGNQ
EEEEEEEECCCCCCC		18.8230622161
524PhosphorylationARKVTFSTHSLGNQH
EEEEEEECCCCCCCC		15.9930622161
526PhosphorylationKVTFSTHSLGNQHIY
EEEEECCCCCCCCEE		37.7530622161
536PhosphorylationNQHIYQRSSSMLSFS
CCCEECCCCCCCCCC		15.9622964224
537PhosphorylationQHIYQRSSSMLSFSN
CCEECCCCCCCCCCC		23.1930622161
538PhosphorylationHIYQRSSSMLSFSNT
CEECCCCCCCCCCCC		25.6222964224
541PhosphorylationQRSSSMLSFSNTDKK
CCCCCCCCCCCCCCH		20.2822964224
543PhosphorylationSSSMLSFSNTDKKAK
CCCCCCCCCCCCHHC		35.1322964224
691PhosphorylationDNGPGQWSDICKVVT
CCCCCCHHHEEEEEC		14.8130622161
717PhosphorylationGLLKNIQSALQKHF-
HHHHHHHHHHHHHC-		27.4430622161
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TRI42_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TRI42_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TRI42_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TRI42_HUMANTRIM42physical
25416956
IHO1_HUMANCCDC36physical
25416956
KLH38_HUMANKLHL38physical
25416956
KR107_HUMANKRTAP10-7physical
25416956
KR109_HUMANKRTAP10-9physical
25416956
KR103_HUMANKRTAP10-3physical
25416956
NT2NL_HUMANNOTCH2NLphysical
25416956
KR261_HUMANKRTAP26-1physical
25416956
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TRI42_HUMAN

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Related Literatures of Post-Translational Modification

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