ADAL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ADAL_HUMAN
• UniProt AC: Q6DHV7
• Protein Name: Adenosine deaminase-like protein
• Gene Name: ADAL
• Organism: Homo sapiens (Human).
• Sequence Length: 355
• Protein Description: Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity)..
• Protein Sequence: MIEAEEQQPCKTDFYSELPKVELHAHLNGSISSHTMKKLIAQKPDLKIHDQMTVIDKGKKRTLEECFQMFQTIHQLTSSPEDILMVTKDVIKEFADDGVKYLELRSTPRRENATGMTKKTYVESILEGIKQSKQENLDIDVRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGTVLGLDLSGDPTVGQAKDFLEPLLEAKKAGLKLALHLSEIPNQKKETQILLDLLPDRIGHGTFLNSGEGGSLDLVDFVRQHRIPLELCLTSNVKSQTVPSYDQHHFGFWYSIAHPSVICTDDKGVFATHLSQEYQLAAETFNLTQSQVWDLSYESINYIFASDSTRSELRKKWNHLKPRVLHI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
92	Ubiquitination	MVTKDVIKEFADDGV EEEHHHHHHHHHCCC	46.78	-
100	Ubiquitination	EFADDGVKYLELRST HHHHCCCEEEEECCC	50.04	-
157	Ubiquitination	RGGPLVAKETVKLAE CCCCEEEHHHHHHHH	46.57	-
200	Ubiquitination	EPLLEAKKAGLKLAL HHHHHHHHHHHHHHH	55.52	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ADAL_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ADAL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ADAL_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ADAL_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.