ELYS_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ELYS_HUMAN
• UniProt AC: Q8WYP5
• Protein Name: Protein ELYS
• Gene Name: AHCTF1
• Organism: Homo sapiens (Human).
• Sequence Length: 2266
• Subcellular Localization: Cytoplasm . Nucleus . Nucleus envelope . Nucleus matrix . Chromosome, centromere, kinetochore . Nucleus, nucleoplasm . Nucleus, nuclear pore complex . Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore fro
• Protein Description: Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis..
• Protein Sequence: MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSITGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQNEVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFSDGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKFRSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDRLCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVSHLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNPDCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLLLDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLSWQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHCNRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQRANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYHLSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNSSKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSMKSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQSILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKKCAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3 (in isoform 2)	Phosphorylation	-	52.98	20860994
8 (in isoform 2)	Phosphorylation	-	4.49	20860994
37	Ubiquitination	LESVLRGKFAAGKNG HHHHHCCCCCCCCCC	25.95	27667366
42	Ubiquitination	RGKFAAGKNGLACLA CCCCCCCCCCEEEEE	43.02	21906983
46	Ubiquitination	AAGKNGLACLACGPQ CCCCCCEEEEEECCC	6.41	27667366
51	Ubiquitination	GLACLACGPQLEVVN CEEEEEECCCEEEEE	13.84	21963094
72	Ubiquitination	LSAYRFSGVNEQPPV CEEEEECCCCCCCCE	24.45	27667366
72 (in isoform 2)	Ubiquitination	-	24.45	-
77	Ubiquitination	FSGVNEQPPVVLAVK ECCCCCCCCEEEEEE	19.92	21963094
77 (in isoform 2)	Ubiquitination	-	19.92	-
80 (in isoform 2)	Ubiquitination	-	3.33	21890473
84	Ubiquitination	PPVVLAVKEFSWQKR CCEEEEEEECCCCCC	47.65	21906983
90	Ubiquitination	VKEFSWQKRTGLLIG EEECCCCCCCCEEEE	45.74	-
92	Phosphorylation	EFSWQKRTGLLIGLE ECCCCCCCCEEEECE	38.94	28851738
93	Ubiquitination	FSWQKRTGLLIGLEE CCCCCCCCEEEECEE	23.63	21963094
99	Ubiquitination	TGLLIGLEETEGSVL CCEEEECEECCCCEE	58.63	-
101	Phosphorylation	LLIGLEETEGSVLCL EEEECEECCCCEEEE	35.95	28851738
114	Phosphorylation	CLYDLGISKVVKAVV EEHHCCCCCEEEEEE	20.01	28851738
118	Ubiquitination	LGISKVVKAVVLPGR CCCCCEEEEEECCCC	38.15	21963094
119	Ubiquitination	GISKVVKAVVLPGRV CCCCEEEEEECCCCE	5.76	21963094
122 (in isoform 2)	Ubiquitination	-	2.75	21890473
125 (in isoform 2)	Ubiquitination	-	22.22	-
127	Ubiquitination	VVLPGRVTAIEPIIN EECCCCEEEEECCCC	22.13	21963094
148	Phosphorylation	STQHLHPSLRWLFGV CCCCCCHHHHHHHHH	21.59	24719451
153	Ubiquitination	HPSLRWLFGVAAVVT CHHHHHHHHHHHEEC	6.17	21963094
153 (in isoform 2)	Ubiquitination	-	6.17	-
217	Phosphorylation	HLCFQLVSPTGTAVS EEEEEEECCCCCHHH	25.90	25072903
219	Phosphorylation	CFQLVSPTGTAVSTL EEEEECCCCCHHHHH	39.39	25072903
221	Phosphorylation	QLVSPTGTAVSTLSY EEECCCCCHHHHHHH	26.77	25072903
224	Phosphorylation	SPTGTAVSTLSYISR CCCCCHHHHHHHHHC	22.59	25072903
225	Phosphorylation	PTGTAVSTLSYISRT CCCCHHHHHHHHHCC	17.08	25072903
227	Phosphorylation	GTAVSTLSYISRTNQ CCHHHHHHHHHCCCC	22.10	25072903
228	Phosphorylation	TAVSTLSYISRTNQL CHHHHHHHHHCCCCE	13.16	25072903
230	Phosphorylation	VSTLSYISRTNQLAV HHHHHHHHCCCCEEE	25.48	25072903
312	Ubiquitination	QLAFGNRKCLASGQI HHHHCCCHHHCCCCC	37.28	-
321	Ubiquitination	LASGQILYEGLEYCE HCCCCCHHHHHHHHC	15.02	-
347 (in isoform 2)	Ubiquitination	-	34.32	-
350	Acetylation	RGQTSNTKLLGCQSI CCCCCCCEEECCEEH	46.06	26051181
350	Ubiquitination	RGQTSNTKLLGCQSI CCCCCCCEEECCEEH	46.06	23000965
359	Acetylation	LGCQSIEKFRSHGDR ECCEEHHHHHCCCCH	44.39	26051181
359	Ubiquitination	LGCQSIEKFRSHGDR ECCEEHHHHHCCCCH	44.39	23000965
368	Ubiquitination	RSHGDREEGVNEALS HCCCCHHCCCCCCCC	70.14	-
385	Ubiquitination	TSVSVFTWQVNIYGQ CEEEEEEEEEEECCC	6.67	23000965
385 (in isoform 2)	Ubiquitination	-	6.67	-
394 (in isoform 2)	Ubiquitination	-	26.65	-
501	Phosphorylation	GFQKETLTFLKKSGP CCCHHHHHHHHHHCC	34.05	-
504	Ubiquitination	KETLTFLKKSGPSLN HHHHHHHHHHCCCHH	40.48	21906983
505	Methylation	ETLTFLKKSGPSLNE HHHHHHHHHCCCHHH	63.89	-
505	Ubiquitination	ETLTFLKKSGPSLNE HHHHHHHHHCCCHHH	63.89	21963094
506	Phosphorylation	TLTFLKKSGPSLNEL HHHHHHHHCCCHHHH	55.11	28122231
509	Phosphorylation	FLKKSGPSLNELIPD HHHHHCCCHHHHCCC	47.56	27499020
510	Phosphorylation	LKKSGPSLNELIPDG HHHHCCCHHHHCCCC	6.94	-
513	Ubiquitination	SGPSLNELIPDGYNR HCCCHHHHCCCCHHH	7.19	21963094
514	Methylation	GPSLNELIPDGYNRC CCCHHHHCCCCHHHH	2.08	-
514	Ubiquitination	GPSLNELIPDGYNRC CCCHHHHCCCCHHHH	2.08	21963094
515	Phosphorylation	PSLNELIPDGYNRCL CCHHHHCCCCHHHHH	41.41	-
518	Phosphorylation	NELIPDGYNRCLVAG HHHCCCCHHHHHHHH	13.55	-
528	Phosphorylation	CLVAGLLSPRFVDVQ HHHHHHCCCCEECCC	21.04	19664994
537	Phosphorylation	RFVDVQPSSLSQEEQ CEECCCCCCCCHHHH	27.16	19664994
539	Ubiquitination	VDVQPSSLSQEEQLE ECCCCCCCCHHHHHH	7.80	21963094
539 (in isoform 2)	Ubiquitination	-	7.80	-
540	Ubiquitination	DVQPSSLSQEEQLEA CCCCCCCCHHHHHHH	37.18	21963094
540 (in isoform 2)	Ubiquitination	-	37.18	-
542 (in isoform 2)	Ubiquitination	-	44.31	21890473
570	Phosphorylation	GYIRRWITEEQPNSA HHHHHHHCCCCCCCC	26.89	29970186
646	Phosphorylation	ASEAREITERGLIDL HHHHHHHHHCCCCCC	18.19	26437602
717	Acetylation	FERLSRGKWNPDCLM HHHHHCCCCCCCCCH	42.56	26051181
717	Ubiquitination	FERLSRGKWNPDCLM HHHHHCCCCCCCCCH	42.56	21963094
726	Ubiquitination	NPDCLMIDGLVSQLG CCCCCHHHHHHHHHH	30.34	21963094
735	Methylation	LVSQLGERIEKLWKR HHHHHHHHHHHHHCC	40.34	-
738	Ubiquitination	QLGERIEKLWKRDEG HHHHHHHHHHCCCCC	58.22	-
747	Phosphorylation	WKRDEGGTGKYPPAS HCCCCCCCCCCCCHH	41.16	-
747	Ubiquitination	WKRDEGGTGKYPPAS HCCCCCCCCCCCCHH	41.16	-
752	Ubiquitination	GGTGKYPPASLHAVL CCCCCCCCHHHHHHH	31.24	21963094
752 (in isoform 2)	Ubiquitination	-	31.24	-
774	Phosphorylation	VTEAAKHSITIYLLL HHHHHHHHHHHHHHH	22.26	25404012
776	Phosphorylation	EAAKHSITIYLLLDI HHHHHHHHHHHHHHH	13.44	25404012
785	Phosphorylation	YLLLDIMYSFPNKTD HHHHHHHHHCCCCCC	13.90	25404012
969	Ubiquitination	ANYVPALKLNQTLKI CCCCCEECCCCEEEE	47.72	21963094
969 (in isoform 1)	Ubiquitination	-	47.72	21890473
975	Ubiquitination	LKLNQTLKINVMNDR ECCCCEEEEEECCCC	35.31	-
978	Ubiquitination	NQTLKINVMNDRDPR CCEEEEEECCCCCHH	4.28	21890473
978 (in isoform 3)	Ubiquitination	-	4.28	-
984	Ubiquitination	NVMNDRDPRLRERSL EECCCCCHHHHHHHH	37.79	-
990	Phosphorylation	DPRLRERSLARNSIL CHHHHHHHHHHHHHH	22.94	24719451
995	Phosphorylation	ERSLARNSILDQYGK HHHHHHHHHHHHHHC	20.98	25159151
1000	Phosphorylation	RNSILDQYGKILPRV HHHHHHHHHCHHHHH	21.76	19691289
1002	Acetylation	SILDQYGKILPRVHR HHHHHHHCHHHHHHH	35.81	26051181
1002	Ubiquitination	SILDQYGKILPRVHR HHHHHHHCHHHHHHH	35.81	21906983
1004	Phosphorylation	LDQYGKILPRVHRKL HHHHHCHHHHHHHHH	2.23	-
1004	Ubiquitination	LDQYGKILPRVHRKL HHHHHCHHHHHHHHH	2.23	21890473
1004 (in isoform 2)	Ubiquitination	-	2.23	-
1007 (in isoform 2)	Ubiquitination	-	4.90	21890473
1010 (in isoform 2)	Ubiquitination	-	27.65	-
1011	Ubiquitination	LPRVHRKLAIERAKP HHHHHHHHHHHHCCC	6.14	21963094
1017	Acetylation	KLAIERAKPYHLSTS HHHHHHCCCCCCCHH	52.94	26051181
1017	Ubiquitination	KLAIERAKPYHLSTS HHHHHHCCCCCCCHH	52.94	-
1022	Phosphorylation	RAKPYHLSTSSVFRL HCCCCCCCHHHHHHH	16.97	23312004
1023	Phosphorylation	AKPYHLSTSSVFRLV CCCCCCCHHHHHHHH	31.23	23312004
1026	Acetylation	YHLSTSSVFRLVSRP CCCCHHHHHHHHCCC	3.03	19608861
1026	Ubiquitination	YHLSTSSVFRLVSRP CCCCHHHHHHHHCCC	3.03	-
1031	Phosphorylation	SSVFRLVSRPKPLSA HHHHHHHCCCCCCCC	47.67	-
1034	Acetylation	FRLVSRPKPLSAVPK HHHHCCCCCCCCCCC	58.44	26051181
1037	Ubiquitination	VSRPKPLSAVPKQVV HCCCCCCCCCCCEEE	35.43	21963094
1037 (in isoform 2)	Ubiquitination	-	35.43	-
1040 (in isoform 2)	Ubiquitination	-	22.52	21890473
1041	Ubiquitination	KPLSAVPKQVVTGTV CCCCCCCCEEECCEE	49.48	23000965
1045	Phosphorylation	AVPKQVVTGTVLTRS CCCCEEECCEECCHH	28.42	30619164
1047	Phosphorylation	PKQVVTGTVLTRSVF CCEEECCEECCHHHH	11.72	30619164
1050	Phosphorylation	VVTGTVLTRSVFINN EECCEECCHHHHHHH	19.30	20068231
1050	Ubiquitination	VVTGTVLTRSVFINN EECCEECCHHHHHHH	19.30	23000965
1052	Phosphorylation	TGTVLTRSVFINNVL CCEECCHHHHHHHHH	19.02	30619164
1052 (in isoform 2)	Ubiquitination	-	19.02	-
1059	Phosphorylation	SVFINNVLSKIGEVW HHHHHHHHHHHCHHH	4.73	-
1060	Phosphorylation	VFINNVLSKIGEVWA HHHHHHHHHHCHHHC	20.25	30619164
1069	Acetylation	IGEVWASKEPINSTT HCHHHCCCCCCCCCC	60.82	26051181
1069	Ubiquitination	IGEVWASKEPINSTT HCHHHCCCCCCCCCC	60.82	23000965
1075	Phosphorylation	SKEPINSTTPFNSSK CCCCCCCCCCCCCCC	33.72	-
1076	Phosphorylation	KEPINSTTPFNSSKI CCCCCCCCCCCCCCC	26.21	25159151
1076	Ubiquitination	KEPINSTTPFNSSKI CCCCCCCCCCCCCCC	26.21	23000965
1076 (in isoform 2)	Ubiquitination	-	26.21	-
1078	Ubiquitination	PINSTTPFNSSKIEE CCCCCCCCCCCCCCC	15.09	23000965
1080	Phosphorylation	NSTTPFNSSKIEEPS CCCCCCCCCCCCCCC	33.13	22199227
1081	Phosphorylation	STTPFNSSKIEEPSP CCCCCCCCCCCCCCC	38.46	21815630
1082	Ubiquitination	TTPFNSSKIEEPSPI CCCCCCCCCCCCCCE	54.69	29967540
1087	Phosphorylation	SSKIEEPSPIVYSLP CCCCCCCCCEEEEEC	30.45	25159151
1089	Phosphorylation	KIEEPSPIVYSLPAP CCCCCCCEEEEECCC	5.50	-
1091	Phosphorylation	EEPSPIVYSLPAPEL CCCCCEEEEECCCCC	12.76	20860994
1091	Ubiquitination	EEPSPIVYSLPAPEL CCCCCEEEEECCCCC	12.76	29967540
1092	Phosphorylation	EPSPIVYSLPAPELP CCCCEEEEECCCCCC	19.58	24732914
1096	Phosphorylation	IVYSLPAPELPEAFF EEEEECCCCCCHHHC	41.54	16565220
1104	Ubiquitination	ELPEAFFGTPISKAS CCCHHHCCCCCHHHH	24.91	23000965
1104 (in isoform 2)	Ubiquitination	-	24.91	-
1105	Phosphorylation	LPEAFFGTPISKASQ CCHHHCCCCCHHHHH	16.58	24732914
1107 (in isoform 2)	Ubiquitination	-	7.10	21890473
1108	Phosphorylation	AFFGTPISKASQKIS HHCCCCCHHHHHHHH	24.31	24732914
1109	Ubiquitination	FFGTPISKASQKISR HCCCCCHHHHHHHHH	53.42	21906983
1113	Ubiquitination	PISKASQKISRLLDL CCHHHHHHHHHHHHH	39.90	23503661
1115	Phosphorylation	SKASQKISRLLDLVV HHHHHHHHHHHHHHH	24.74	20068231
1117	Phosphorylation	ASQKISRLLDLVVQP HHHHHHHHHHHHHCC	3.31	-
1118	Ubiquitination	SQKISRLLDLVVQPV HHHHHHHHHHHHCCC	4.68	21963094
1122	Ubiquitination	SRLLDLVVQPVPRPS HHHHHHHHCCCCCHH	7.47	23503661
1129	Phosphorylation	VQPVPRPSQCSEFIQ HCCCCCHHHHHHHHH	45.13	27174698
1132	Phosphorylation	VPRPSQCSEFIQQSS CCCHHHHHHHHHHHC	28.09	27174698
1138	Phosphorylation	CSEFIQQSSMKSPLY HHHHHHHHCCCCCEE	18.94	29978859
1139	Phosphorylation	SEFIQQSSMKSPLYL HHHHHHHCCCCCEEE	26.37	30576142
1141	Acetylation	FIQQSSMKSPLYLVS HHHHHCCCCCEEEEE	51.36	26051181
1141	Ubiquitination	FIQQSSMKSPLYLVS HHHHHCCCCCEEEEE	51.36	-
1142	Phosphorylation	IQQSSMKSPLYLVSR HHHHCCCCCEEEEEC	16.11	22167270
1144	Ubiquitination	QSSMKSPLYLVSRSL HHCCCCCEEEEECCC	7.15	21963094
1144 (in isoform 2)	Ubiquitination	-	7.15	-
1145	Phosphorylation	SSMKSPLYLVSRSLP HCCCCCEEEEECCCC	14.40	27794612
1147 (in isoform 2)	Ubiquitination	-	2.56	21890473
1148	Phosphorylation	KSPLYLVSRSLPSSS CCCEEEEECCCCCHH	17.35	23898821
1148	Ubiquitination	KSPLYLVSRSLPSSS CCCEEEEECCCCCHH	17.35	23503661
1150	Phosphorylation	PLYLVSRSLPSSSQL CEEEEECCCCCHHHC	36.81	25159151
1150	Ubiquitination	PLYLVSRSLPSSSQL CEEEEECCCCCHHHC	36.81	-
1151	Phosphorylation	LYLVSRSLPSSSQLK EEEEECCCCCHHHCC	4.66	32142685
1153	Phosphorylation	LVSRSLPSSSQLKGS EEECCCCCHHHCCCC	48.17	30266825
1154	Phosphorylation	VSRSLPSSSQLKGSP EECCCCCHHHCCCCH	21.84	30266825
1155	Phosphorylation	SRSLPSSSQLKGSPQ ECCCCCHHHCCCCHH	43.82	30266825
1158	Acetylation	LPSSSQLKGSPQAIS CCCHHHCCCCHHHHH	50.10	26051181
1158	Ubiquitination	LPSSSQLKGSPQAIS CCCHHHCCCCHHHHH	50.10	23000965
1159	Phosphorylation	PSSSQLKGSPQAISR CCHHHCCCCHHHHHH	53.82	18669648
1160	Phosphorylation	SSSQLKGSPQAISRA CHHHCCCCHHHHHHH	16.55	22167270
1162	Phosphorylation	SQLKGSPQAISRASE HHCCCCHHHHHHHHH	53.69	-
1163	Phosphorylation	QLKGSPQAISRASEL HCCCCHHHHHHHHHH	12.71	18669648
1164	Phosphorylation	LKGSPQAISRASELH CCCCHHHHHHHHHHH	2.11	18669648
1165	Phosphorylation	KGSPQAISRASELHL CCCHHHHHHHHHHHH	25.47	30266825
1167	Ubiquitination	SPQAISRASELHLLE CHHHHHHHHHHHHCC	10.68	23000965
1168	Phosphorylation	PQAISRASELHLLET HHHHHHHHHHHHCCC	39.31	21815630
1169	Phosphorylation	QAISRASELHLLETP HHHHHHHHHHHCCCC	38.94	18669648
1175	Phosphorylation	SELHLLETPLVVKKA HHHHHCCCCHHHHHH	23.15	29255136
1176 (in isoform 2)	Ubiquitination	-	17.49	-
1177	Phosphorylation	LHLLETPLVVKKAKS HHHCCCCHHHHHHHH	10.12	-
1180	Acetylation	LETPLVVKKAKSLAM CCCCHHHHHHHHHCC	39.26	25953088
1181	Ubiquitination	ETPLVVKKAKSLAMS CCCHHHHHHHHHCCE	49.81	-
1183	Acetylation	PLVVKKAKSLAMSVT CHHHHHHHHHCCEEC	55.68	10735673
1184	Phosphorylation	LVVKKAKSLAMSVTT HHHHHHHHHCCEECC	26.64	18669648
1188	Phosphorylation	KAKSLAMSVTTSGFS HHHHHCCEECCCCCC	15.65	18669648
1191	Phosphorylation	SLAMSVTTSGFSEFT HHCCEECCCCCCCCC	25.38	21712546
1192	Phosphorylation	LAMSVTTSGFSEFTP HCCEECCCCCCCCCH	28.60	18669648
1193	Ubiquitination	AMSVTTSGFSEFTPQ CCEECCCCCCCCCHH	28.18	23000965
1193 (in isoform 2)	Ubiquitination	-	28.18	-
1195	Phosphorylation	SVTTSGFSEFTPQSI EECCCCCCCCCHHHH	35.01	19691289
1198	Phosphorylation	TSGFSEFTPQSILRS CCCCCCCCHHHHHHH	19.16	20860994
1200	Phosphorylation	GFSEFTPQSILRSTL CCCCCCHHHHHHHHH	39.79	-
1201	Phosphorylation	FSEFTPQSILRSTLR CCCCCHHHHHHHHHC	25.46	20860994
1205	Phosphorylation	TPQSILRSTLRSTPL CHHHHHHHHHCCCCC	28.48	21955146
1206	Phosphorylation	PQSILRSTLRSTPLA HHHHHHHHHCCCCCC	21.54	22115753
1207	Phosphorylation	QSILRSTLRSTPLAS HHHHHHHHCCCCCCC	4.25	-
1209	Phosphorylation	ILRSTLRSTPLASPS HHHHHHCCCCCCCCC	37.17	23927012
1210	Phosphorylation	LRSTLRSTPLASPSP HHHHHCCCCCCCCCC	18.85	30278072
1214	Phosphorylation	LRSTPLASPSPSPGR HCCCCCCCCCCCCCC	33.33	29255136
1215	Phosphorylation	RSTPLASPSPSPGRS CCCCCCCCCCCCCCC	44.65	18669648
1216	Phosphorylation	STPLASPSPSPGRSP CCCCCCCCCCCCCCH	35.20	29255136
1216 (in isoform 2)	Ubiquitination	-	35.20	-
1218	Phosphorylation	PLASPSPSPGRSPQR CCCCCCCCCCCCHHH	44.30	29255136
1219	Phosphorylation	LASPSPSPGRSPQRL CCCCCCCCCCCHHHH	45.67	18669648
1222	Phosphorylation	PSPSPGRSPQRLKET CCCCCCCCHHHHHHH	31.16	22167270
1223	Phosphorylation	SPSPGRSPQRLKETR CCCCCCCHHHHHHHE	23.19	18669648
1225	Phosphorylation	SPGRSPQRLKETRIS CCCCCHHHHHHHEEE	51.62	18669648
1226 (in isoform 2)	Phosphorylation	-	5.04	18669648
1227	Phosphorylation	GRSPQRLKETRISFV CCCHHHHHHHEEEEE	60.26	33259812
1229	Phosphorylation	SPQRLKETRISFVEE CHHHHHHHEEEEECC	31.54	23401153
1230 (in isoform 2)	Phosphorylation	-	24.52	18669648
1231	Phosphorylation	QRLKETRISFVEEDV HHHHHHEEEEECCCC	4.97	18669648
1232	Phosphorylation	RLKETRISFVEEDVH HHHHHEEEEECCCCC	21.68	29255136
1238	Phosphorylation	ISFVEEDVHPKWIPG EEEECCCCCCCCCCC	10.61	32645325
1241	Phosphorylation	VEEDVHPKWIPGAAD ECCCCCCCCCCCCCC	42.76	18669648
1241	Ubiquitination	VEEDVHPKWIPGAAD ECCCCCCCCCCCCCC	42.76	29967540
1250	Phosphorylation	IPGAADDSKLEVFTT CCCCCCCCCEEEEEC	39.42	25159151
1250	Ubiquitination	IPGAADDSKLEVFTT CCCCCCCCCEEEEEC	39.42	29967540
1251	Ubiquitination	PGAADDSKLEVFTTP CCCCCCCCEEEEECC	56.51	29967540
1256	Phosphorylation	DSKLEVFTTPKKCAV CCCEEEEECCCCCCC	47.57	30266825
1257	Phosphorylation	SKLEVFTTPKKCAVP CCEEEEECCCCCCCE	22.96	30266825
1259	Phosphorylation	LEVFTTPKKCAVPVE EEEEECCCCCCCEEC	59.39	18669648
1259	Ubiquitination	LEVFTTPKKCAVPVE EEEEECCCCCCCEEC	59.39	33845483
1260	Ubiquitination	EVFTTPKKCAVPVET EEEECCCCCCCEECC	28.73	29967540
1265	Phosphorylation	PKKCAVPVETEWLKS CCCCCCEECCHHHHC	13.13	18669648
1266	Phosphorylation	KKCAVPVETEWLKSK CCCCCEECCHHHHCC	34.63	18669648
1267	Phosphorylation	KCAVPVETEWLKSKD CCCCEECCHHHHCCC	32.47	18669648
1268	Ubiquitination	CAVPVETEWLKSKDR CCCEECCHHHHCCCC	36.99	33845483
1269	Ubiquitination	AVPVETEWLKSKDRT CCEECCHHHHCCCCC	19.26	29967540
1272	Phosphorylation	VETEWLKSKDRTTSF ECCHHHHCCCCCCCC	37.30	21712546
1276	Phosphorylation	WLKSKDRTTSFFLNS HHHCCCCCCCCCCCC	36.60	23927012
1277	Phosphorylation	LKSKDRTTSFFLNSP HHCCCCCCCCCCCCC	25.16	25159151
1278	Phosphorylation	KSKDRTTSFFLNSPE HCCCCCCCCCCCCCH	17.25	23927012
1281	Phosphorylation	DRTTSFFLNSPEKEH CCCCCCCCCCCHHHH	6.13	-
1283	Phosphorylation	TTSFFLNSPEKEHQE CCCCCCCCCHHHHHH	36.26	19664994
1285	Phosphorylation	SFFLNSPEKEHQEMD CCCCCCCHHHHHHCC	71.54	-
1286	Acetylation	FFLNSPEKEHQEMDE CCCCCCHHHHHHCCH	64.97	26051181
1287	Phosphorylation	FLNSPEKEHQEMDEG CCCCCHHHHHHCCHH	49.49	-
1292	Phosphorylation	EKEHQEMDEGSQSLE HHHHHHCCHHCCCHH	57.25	32142685
1295	Phosphorylation	HQEMDEGSQSLEKLD HHHCCHHCCCHHHCC	17.97	23401153
1297	Phosphorylation	EMDEGSQSLEKLDVS HCCHHCCCHHHCCCC	39.95	30266825
1300	Ubiquitination	EGSQSLEKLDVSKGN HHCCCHHHCCCCCCC	56.11	29967540
1304	Phosphorylation	SLEKLDVSKGNSSVS CHHHCCCCCCCCCEE	34.22	17525332
1305 (in isoform 2)	Phosphorylation	-	63.06	18669648
1306	Phosphorylation	EKLDVSKGNSSVSIT HHCCCCCCCCCEEEC	31.57	-
1308	Phosphorylation	LDVSKGNSSVSITSD CCCCCCCCCEEECCC	40.56	23090842
1309	Phosphorylation	DVSKGNSSVSITSDE CCCCCCCCEEECCCC	24.71	23090842
1309	Ubiquitination	DVSKGNSSVSITSDE CCCCCCCCEEECCCC	24.71	29967540
1311	Phosphorylation	SKGNSSVSITSDETT CCCCCCEEECCCCCE	23.30	18669648
1313	Phosphorylation	GNSSVSITSDETTLE CCCCEEECCCCCEEE	23.71	23090842
1314	Phosphorylation	NSSVSITSDETTLEY CCCEEECCCCCEEEE	31.60	18669648
1317	Phosphorylation	VSITSDETTLEYQDA EEECCCCCEEEECCC	41.49	23090842
1318	Phosphorylation	SITSDETTLEYQDAP EECCCCCEEEECCCC	18.62	23090842
1320	Phosphorylation	TSDETTLEYQDAPSP CCCCCEEEECCCCCH	38.77	18669648
1321	Phosphorylation	SDETTLEYQDAPSPE CCCCEEEECCCCCHH	18.14	24144214
1323	Phosphorylation	ETTLEYQDAPSPEDL CCEEEECCCCCHHHH	60.59	18669648
1326	Phosphorylation	LEYQDAPSPEDLEET EEECCCCCHHHHHHH	42.51	18452278
1333	Phosphorylation	SPEDLEETVFTASKP CHHHHHHHEEECCCC	16.14	30576142
1336	Phosphorylation	DLEETVFTASKPKSS HHHHHEEECCCCCCC	26.19	30177828
1338	Phosphorylation	EETVFTASKPKSSST HHHEEECCCCCCCCC	46.57	30177828
1341	Ubiquitination	VFTASKPKSSSTALT EEECCCCCCCCCEEE	67.70	29967540
1342	Phosphorylation	FTASKPKSSSTALTT EECCCCCCCCCEEEE	37.74	25159151
1343	Phosphorylation	TASKPKSSSTALTTN ECCCCCCCCCEEEEC	37.52	25159151
1344	Phosphorylation	ASKPKSSSTALTTNV CCCCCCCCCEEEECC	25.45	30576142
1345	Phosphorylation	SKPKSSSTALTTNVT CCCCCCCCEEEECCC	27.86	21815630
1348	Phosphorylation	KSSSTALTTNVTEQT CCCCCEEEECCCCCC	17.54	24732914
1349	Phosphorylation	SSSTALTTNVTEQTE CCCCEEEECCCCCCC	28.65	27174698
1350	Ubiquitination	SSTALTTNVTEQTEK CCCEEEECCCCCCCC	33.21	29967540
1352	Phosphorylation	TALTTNVTEQTEKDG CEEEECCCCCCCCCC	25.17	27174698
1355	Phosphorylation	TTNVTEQTEKDGDKD EECCCCCCCCCCCCC	38.48	27174698
1357	Acetylation	NVTEQTEKDGDKDVF CCCCCCCCCCCCCCE	71.10	26051181
1357	Ubiquitination	NVTEQTEKDGDKDVF CCCCCCCCCCCCCCE	71.10	33845483
1361	Ubiquitination	QTEKDGDKDVFASEV CCCCCCCCCCEECCC	62.41	29967540
1366	Phosphorylation	GDKDVFASEVTPSDL CCCCCEECCCCHHHH	22.57	30266825
1366	Ubiquitination	GDKDVFASEVTPSDL CCCCCEECCCCHHHH	22.57	33845483
1369	Phosphorylation	DVFASEVTPSDLQKQ CCEECCCCHHHHHHH	17.02	30266825
1370	Ubiquitination	VFASEVTPSDLQKQM CEECCCCHHHHHHHH	30.90	29967540
1371	Phosphorylation	FASEVTPSDLQKQMG EECCCCHHHHHHHHC	41.40	30266825
1375	Ubiquitination	VTPSDLQKQMGNLED CCHHHHHHHHCCCCC	49.93	29967540
1378	Phosphorylation	SDLQKQMGNLEDAET HHHHHHHCCCCCHHH	32.83	-
1380	Phosphorylation	LQKQMGNLEDAETKD HHHHHCCCCCHHHHH	5.37	-
1384	Ubiquitination	MGNLEDAETKDLLVA HCCCCCHHHHHHHHH	69.57	29967540
1396	Phosphorylation	LVAAEAFSELNHLSP HHHHHHHHHCCCCCC	48.50	28387310
1402	Phosphorylation	FSELNHLSPVQGTEA HHHCCCCCCCCCCCC	18.57	29496963
1407	Phosphorylation	HLSPVQGTEASLCAP CCCCCCCCCCCCCCC	15.99	30108239
1410	Phosphorylation	PVQGTEASLCAPSVY CCCCCCCCCCCCCEE	20.11	26657352
1411	Phosphorylation	VQGTEASLCAPSVYE CCCCCCCCCCCCEEC	3.58	-
1415	Phosphorylation	EASLCAPSVYEGKIF CCCCCCCCEECCCCC	20.85	30108239
1425	Acetylation	EGKIFTQKSKVPVLD CCCCCCCCCCCCEEC	49.54	25953088
1426	Phosphorylation	GKIFTQKSKVPVLDE CCCCCCCCCCCEECC	29.12	30576142
1436	Phosphorylation	PVLDEGLTSVETYTP CEECCCCCCEEECCC	41.40	-
1437	Phosphorylation	VLDEGLTSVETYTPA EECCCCCCEEECCCC	24.01	28555341
1442	Phosphorylation	LTSVETYTPAIRAND CCCEEECCCCCCCCC	17.42	27050516
1445	Phosphorylation	VETYTPAIRANDNKS EEECCCCCCCCCCCC	4.50	-
1451	Phosphorylation	AIRANDNKSMADVLG CCCCCCCCCHHHHHC	44.46	-
1452	Phosphorylation	IRANDNKSMADVLGD CCCCCCCCHHHHHCC	26.00	23663014
1461	Phosphorylation	ADVLGDGGNSSLTIS HHHHCCCCCCCEEEC	35.27	-
1463	Phosphorylation	VLGDGGNSSLTISEG HHCCCCCCCEEECCC	29.96	23663014
1464	Phosphorylation	LGDGGNSSLTISEGP HCCCCCCCEEECCCC	33.27	23663014
1466	Phosphorylation	DGGNSSLTISEGPIV CCCCCCEEECCCCCC	25.14	23663014
1468	Phosphorylation	GNSSLTISEGPIVSE CCCCEEECCCCCCCE	31.13	23663014
1474	Phosphorylation	ISEGPIVSERRLNQE ECCCCCCCEECCCHH	26.55	20068231
1500	Phosphorylation	EVGVLKESVDLPEEK EEEEEECCCCCCHHH	21.24	22210691
1507	Ubiquitination	SVDLPEEKLPISDSP CCCCCHHHCCCCCCC	58.88	29967540
1511	Phosphorylation	PEEKLPISDSPPDTQ CHHHCCCCCCCCCCC	30.05	30266825
1513	Phosphorylation	EKLPISDSPPDTQEI HHCCCCCCCCCCCEE	31.38	22167270
1516	Ubiquitination	PISDSPPDTQEIHVI CCCCCCCCCCEEEEE	65.49	29967540
1517	Phosphorylation	ISDSPPDTQEIHVIE CCCCCCCCCEEEEEE	33.60	30266825
1520	Phosphorylation	SPPDTQEIHVIEQEK CCCCCCEEEEEEHHH	1.95	-
1522	Phosphorylation	PDTQEIHVIEQEKLE CCCCEEEEEEHHHHH	6.73	18669648
1526	Phosphorylation	EIHVIEQEKLEAQDS EEEEEEHHHHHCCCC	46.98	32142685
1527	Ubiquitination	IHVIEQEKLEAQDSG EEEEEHHHHHCCCCC	51.85	33845483
1533	Phosphorylation	EKLEAQDSGEEARNL HHHHCCCCCHHHHCC	35.70	30266825
1536	Ubiquitination	EAQDSGEEARNLSFN HCCCCCHHHHCCCCC	57.35	33845483
1541	Phosphorylation	GEEARNLSFNELYPS CHHHHCCCCCCCCCC	29.58	29255136
1542	Phosphorylation	EEARNLSFNELYPSG HHHHCCCCCCCCCCC	10.43	18669648
1546	Phosphorylation	NLSFNELYPSGTLKL CCCCCCCCCCCCEEE	6.81	30266825
1548	Phosphorylation	SFNELYPSGTLKLQY CCCCCCCCCCEEEEE	30.74	23927012
1550	Phosphorylation	NELYPSGTLKLQYNF CCCCCCCCEEEEECC	25.67	24732914
1552	Ubiquitination	LYPSGTLKLQYNFDT CCCCCCEEEEECCCC	33.12	29967540
1561	Ubiquitination	QYNFDTIDQQFCDLA EECCCCCCHHHHHHC	38.02	29967540
1620	Phosphorylation	VLPKAANTATEEKLV CCCCCCCCCCCCCEE	30.17	19007248
1625	Acetylation	ANTATEEKLVCSGEN CCCCCCCCEEECCCC	39.73	26051181
1625	Ubiquitination	ANTATEEKLVCSGEN CCCCCCCCEEECCCC	39.73	29967540
1629	Phosphorylation	TEEKLVCSGENDNHG CCCCEEECCCCCCCC	41.48	25850435
1634	Ubiquitination	VCSGENDNHGQIANL EECCCCCCCCCCCCC	53.42	29967540
1638	Phosphorylation	ENDNHGQIANLPSAV CCCCCCCCCCCCCCC	3.04	-
1643	Phosphorylation	GQIANLPSAVTSDQK CCCCCCCCCCCCCCC	38.24	28555341
1647	Phosphorylation	NLPSAVTSDQKSQKV CCCCCCCCCCCCCCC	31.29	25159151
1650	Ubiquitination	SAVTSDQKSQKVDTL CCCCCCCCCCCCCCC	60.90	33845483
1653	Acetylation	TSDQKSQKVDTLPYV CCCCCCCCCCCCCCC	49.52	26051181
1653	Ubiquitination	TSDQKSQKVDTLPYV CCCCCCCCCCCCCCC	49.52	29967540
1656	Phosphorylation	QKSQKVDTLPYVPEP CCCCCCCCCCCCCCC	32.40	21406692
1659	Phosphorylation	QKVDTLPYVPEPIKV CCCCCCCCCCCCHHH	31.58	21406692
1659	Ubiquitination	QKVDTLPYVPEPIKV CCCCCCCCCCCCHHH	31.58	33845483
1662	Ubiquitination	DTLPYVPEPIKVAIA CCCCCCCCCHHHHHH	50.00	29967540
1665	Phosphorylation	PYVPEPIKVAIAENL CCCCCCHHHHHHHHH	36.01	-
1665	Ubiquitination	PYVPEPIKVAIAENL CCCCCCHHHHHHHHH	36.01	29967540
1668	Phosphorylation	PEPIKVAIAENLLDV CCCHHHHHHHHHHHH	5.75	-
1674	Ubiquitination	AIAENLLDVIKDTRS HHHHHHHHHHHHCCC	43.17	29967540
1677	Ubiquitination	ENLLDVIKDTRSKEI HHHHHHHHHCCCCCC	53.55	33845483
1679	Phosphorylation	LLDVIKDTRSKEITS HHHHHHHCCCCCCCC	31.66	22210691
1682	Ubiquitination	VIKDTRSKEITSDTM HHHHCCCCCCCCCHH	50.25	23503661
1685	Phosphorylation	DTRSKEITSDTMEQS HCCCCCCCCCHHHHH	22.95	22210691
1686	Phosphorylation	TRSKEITSDTMEQSI CCCCCCCCCHHHHHH	36.42	22210691
1686	Ubiquitination	TRSKEITSDTMEQSI CCCCCCCCCHHHHHH	36.42	33845483
1688	Phosphorylation	SKEITSDTMEQSIHE CCCCCCCHHHHHHHH	23.52	22210691
1691	Ubiquitination	ITSDTMEQSIHETIP CCCCHHHHHHHHHCH	36.54	23503661
1692	Phosphorylation	TSDTMEQSIHETIPL CCCHHHHHHHHHCHH	16.77	19007248
1696	Phosphorylation	MEQSIHETIPLVSQN HHHHHHHHCHHHCCC	17.46	22210691
1701	Phosphorylation	HETIPLVSQNIMCPT HHHCHHHCCCCCCCH	25.78	19007248
1708	Phosphorylation	SQNIMCPTKLVKSAF CCCCCCCHHHHHHHH	31.89	22210691
1709	Acetylation	QNIMCPTKLVKSAFK CCCCCCHHHHHHHHH	36.10	26051181
1712	Ubiquitination	MCPTKLVKSAFKTAQ CCCHHHHHHHHHHHH	46.64	23503661
1712 (in isoform 2)	Ubiquitination	-	46.64	-
1713	Phosphorylation	CPTKLVKSAFKTAQE CCHHHHHHHHHHHHH	31.30	24144214
1715 (in isoform 2)	Ubiquitination	-	10.49	21890473
1716	Acetylation	KLVKSAFKTAQETST HHHHHHHHHHHHHCC	42.54	25953088
1716	Methylation	KLVKSAFKTAQETST HHHHHHHHHHHHHCC	42.54	-
1717	Phosphorylation	LVKSAFKTAQETSTM HHHHHHHHHHHHCCC	27.41	24144214
1717	Ubiquitination	LVKSAFKTAQETSTM HHHHHHHHHHHHCCC	27.41	23503661
1721	Phosphorylation	AFKTAQETSTMTMNV HHHHHHHHCCCEEEH	19.88	24144214
1721	Ubiquitination	AFKTAQETSTMTMNV HHHHHHHHCCCEEEH	19.88	29967540
1722	Phosphorylation	FKTAQETSTMTMNVS HHHHHHHCCCEEEHH	18.54	24144214
1723	Phosphorylation	KTAQETSTMTMNVSQ HHHHHHCCCEEEHHH	24.87	24144214
1725	Methylation	AQETSTMTMNVSQVD HHHHCCCEEEHHHHH	12.99	-
1725	Phosphorylation	AQETSTMTMNVSQVD HHHHCCCEEEHHHHH	12.99	24144214
1729	Phosphorylation	STMTMNVSQVDDVVS CCCEEEHHHHHHHHH	21.34	21712546
1736	Phosphorylation	SQVDDVVSSKTRTRG HHHHHHHHCCCCCCC	26.43	24144214
1737	Phosphorylation	QVDDVVSSKTRTRGQ HHHHHHHCCCCCCCC	26.83	19060867
1738	Acetylation	VDDVVSSKTRTRGQR HHHHHHCCCCCCCCE	34.22	25953088
1738	Phosphorylation	VDDVVSSKTRTRGQR HHHHHHCCCCCCCCE	34.22	18669648
1753	Phosphorylation	IQNVNVKSAQQEASA EECCCCCHHHHHHCC	27.33	27174698
1759	Phosphorylation	KSAQQEASADVATPK CHHHHHHCCCCCCCC	25.01	29396449
1764	Phosphorylation	EASADVATPKMPGQS HHCCCCCCCCCCCHH	24.24	25159151
1766	Acetylation	SADVATPKMPGQSVR CCCCCCCCCCCHHHH	54.06	26051181
1771	Phosphorylation	TPKMPGQSVRKKTRK CCCCCCHHHHHHHHH	29.79	25159151
1773	Phosphorylation	KMPGQSVRKKTRKAK CCCCHHHHHHHHHHH	39.75	-
1780	Phosphorylation	RKKTRKAKEISEASE HHHHHHHHHHHHHHH	59.63	-
1780	Ubiquitination	RKKTRKAKEISEASE HHHHHHHHHHHHHHH	59.63	29967540
1786	Phosphorylation	AKEISEASENIYSDV HHHHHHHHHHHHHHH	27.42	20860994
1789	Ubiquitination	ISEASENIYSDVRGL HHHHHHHHHHHHHCC	2.82	29967540
1790	Phosphorylation	SEASENIYSDVRGLS HHHHHHHHHHHHCCC	15.48	25884760
1791	Phosphorylation	EASENIYSDVRGLSQ HHHHHHHHHHHCCCC	26.32	25348954
1795	Phosphorylation	NIYSDVRGLSQNQQI HHHHHHHCCCCCCCC	29.54	-
1797	Phosphorylation	YSDVRGLSQNQQIPQ HHHHHCCCCCCCCCC	29.88	24732914
1799	Phosphorylation	DVRGLSQNQQIPQNS HHHCCCCCCCCCCCC	32.14	-
1800	Phosphorylation	VRGLSQNQQIPQNSV HHCCCCCCCCCCCCC	34.64	-
1806	Phosphorylation	NQQIPQNSVTPRRGR CCCCCCCCCCCCCCC	23.32	25159151
1808	Phosphorylation	QIPQNSVTPRRGRRK CCCCCCCCCCCCCCH	15.76	25159151
1815	Phosphorylation	TPRRGRRKKEVNQDI CCCCCCCHHHHCHHH	52.50	18669648
1817	Phosphorylation	RRGRRKKEVNQDILE CCCCCHHHHCHHHHH	50.14	18669648
1826	Phosphorylation	NQDILENTSSVEQEL CHHHHHCCCCHHHHH	17.01	27732954
1827	Phosphorylation	QDILENTSSVEQELQ HHHHHCCCCHHHHHH	43.92	20860994
1828	Phosphorylation	DILENTSSVEQELQI HHHHCCCCHHHHHHH	27.86	27732954
1836	Phosphorylation	VEQELQITTGRESKR HHHHHHHHCCCCCCC	15.38	-
1841	Phosphorylation	QITTGRESKRLKSSQ HHHCCCCCCCCCCCC	23.01	28555341
1846	Phosphorylation	RESKRLKSSQLLEPA CCCCCCCCCCCCHHH	28.10	22199227
1847	Phosphorylation	ESKRLKSSQLLEPAV CCCCCCCCCCCHHHH	24.22	22199227
1857	Phosphorylation	LEPAVEETTKKEVKV CHHHHHHHCCCEEEH	30.34	23312004
1858	Phosphorylation	EPAVEETTKKEVKVS HHHHHHHCCCEEEHH	43.32	23312004
1865	Phosphorylation	TKKEVKVSSVTKRTP CCCEEEHHHCCCCCC	17.24	20860994
1866	Phosphorylation	KKEVKVSSVTKRTPR CCEEEHHHCCCCCCH	36.47	25159151
1868	Phosphorylation	EVKVSSVTKRTPRRI EEEHHHCCCCCCHHH	19.43	25159151
1871	Phosphorylation	VSSVTKRTPRRIKRS HHHCCCCCCHHHHHH	23.78	25159151
1875	Phosphorylation	TKRTPRRIKRSVENQ CCCCCHHHHHHHCCH	4.61	-
1877	Phosphorylation	RTPRRIKRSVENQES CCCHHHHHHHCCHHH	43.49	-
1878	Phosphorylation	TPRRIKRSVENQESV CCHHHHHHHCCHHHE	28.87	30266825
1880	Phosphorylation	RRIKRSVENQESVEI HHHHHHHCCHHHEEE	55.21	-
1884	Phosphorylation	RSVENQESVEIINDL HHHCCHHHEEEECCC	18.45	30266825
1887	Phosphorylation	ENQESVEIINDLKVS CCHHHEEEECCCEEE	3.14	18669648
1893	Phosphorylation	EIINDLKVSTVTSPS EEECCCEEEECCCHH	8.24	18669648
1894	Phosphorylation	IINDLKVSTVTSPSR EECCCEEEECCCHHH	18.64	30266825
1895	Phosphorylation	INDLKVSTVTSPSRM ECCCEEEECCCHHHH	30.69	30266825
1897	Phosphorylation	DLKVSTVTSPSRMIR CCEEEECCCHHHHHH	34.70	30266825
1898	Phosphorylation	LKVSTVTSPSRMIRK CEEEECCCHHHHHHH	19.28	30266825
1900	Phosphorylation	VSTVTSPSRMIRKLR EEECCCHHHHHHHHH	33.96	30266825
1907	Phosphorylation	SRMIRKLRSTNLDAS HHHHHHHHHCCCCCC	44.46	18669648
1908	Phosphorylation	RMIRKLRSTNLDASE HHHHHHHHCCCCCCC	31.89	22496350
1909	Phosphorylation	MIRKLRSTNLDASEN HHHHHHHCCCCCCCC	33.11	25159151
1914	Phosphorylation	RSTNLDASENTGNKQ HHCCCCCCCCCCCCC	30.92	21815630
1917	Phosphorylation	NLDASENTGNKQDDK CCCCCCCCCCCCCCC	37.77	21815630
1923	Phosphorylation	NTGNKQDDKSSDKQL CCCCCCCCCCCCHHH	50.68	-
1925	Phosphorylation	GNKQDDKSSDKQLRI CCCCCCCCCCHHHHH	51.25	26055452
1926	Phosphorylation	NKQDDKSSDKQLRIK CCCCCCCCCHHHHHH	55.35	21712546
1934	Phosphorylation	DKQLRIKHVRRVRGR CHHHHHHHHHHHCCC	18.88	-
1935	Phosphorylation	KQLRIKHVRRVRGRE HHHHHHHHHHHCCCC	3.38	-
1944	Phosphorylation	RVRGREVSPSDVRED HHCCCCCCHHHHCCC	17.59	29255136
1946	Phosphorylation	RGREVSPSDVREDSN CCCCCCHHHHCCCCC	41.03	23401153
1952	Phosphorylation	PSDVREDSNLESSQL HHHHCCCCCCCCCCE	38.26	28464451
1953	Phosphorylation	SDVREDSNLESSQLT HHHCCCCCCCCCCEE	61.21	18669648
1955	Phosphorylation	VREDSNLESSQLTVQ HCCCCCCCCCCEEEE	53.23	-
1956	Phosphorylation	REDSNLESSQLTVQA CCCCCCCCCCEEEEE	26.93	30242111
1957	Phosphorylation	EDSNLESSQLTVQAE CCCCCCCCCEEEEEE	21.60	30242111
1960	Phosphorylation	NLESSQLTVQAEFDM CCCCCCEEEEEEECH	11.70	27174698
1968	Phosphorylation	VQAEFDMSAIPRKRG EEEEECHHHCCHHCC	25.53	24719451
1983	Phosphorylation	RPRKINPSEDVGSKA CCCCCCCCCCCCCHH	41.77	20068231
1988	Phosphorylation	NPSEDVGSKAVKEER CCCCCCCCHHHHHCC	19.79	20068231
1996	Phosphorylation	KAVKEERSPKKKEAP HHHHHCCCCCCCCCC	44.33	28176443
1997	Phosphorylation	AVKEERSPKKKEAPS HHHHCCCCCCCCCCC	59.72	-
2005	Phosphorylation	KKKEAPSIRRRSTRN CCCCCCCHHHHCCCC	3.75	17081983
2009	Phosphorylation	APSIRRRSTRNTPAK CCCHHHHCCCCCCCC	29.88	24732914
2010	Phosphorylation	PSIRRRSTRNTPAKS CCHHHHCCCCCCCCC	26.57	24732914
2013	Phosphorylation	RRRSTRNTPAKSENV HHHCCCCCCCCCCCC	22.72	28387310
2016	Acetylation	STRNTPAKSENVDVG CCCCCCCCCCCCCCC	60.55	26051181
2017	Phosphorylation	TRNTPAKSENVDVGK CCCCCCCCCCCCCCC	36.19	24732914
2022	Phosphorylation	AKSENVDVGKPALGK CCCCCCCCCCCCCCC	10.39	-
2024	Acetylation	SENVDVGKPALGKSI CCCCCCCCCCCCCEE	27.28	23954790
2024	Ubiquitination	SENVDVGKPALGKSI CCCCCCCCCCCCCEE	27.28	29967540
2026	Phosphorylation	NVDVGKPALGKSILV CCCCCCCCCCCEEEC	32.22	-
2030	Phosphorylation	GKPALGKSILVPNEE CCCCCCCEEECCCHH	21.25	28555341
2033	Acetylation	ALGKSILVPNEELSM CCCCEEECCCHHHHH	4.57	-
2033	Ubiquitination	ALGKSILVPNEELSM CCCCEEECCCHHHHH	4.57	29967540
2039	Phosphorylation	LVPNEELSMVMSSKK ECCCHHHHHHHHCCC	16.77	22199227
2043	Phosphorylation	EELSMVMSSKKKLTK HHHHHHHHCCCCCCH	27.82	21815630
2044	Phosphorylation	ELSMVMSSKKKLTKK HHHHHHHCCCCCCHH	30.33	21815630
2045	Acetylation	LSMVMSSKKKLTKKT HHHHHHCCCCCCHHC	46.77	25953088
2046	Acetylation	SMVMSSKKKLTKKTE HHHHHCCCCCCHHCC	55.77	25953088
2052	Phosphorylation	KKKLTKKTESQSQKR CCCCCHHCCCHHHHH	42.28	-
2053	Phosphorylation	KKLTKKTESQSQKRS CCCCHHCCCHHHHHH	56.51	-
2060	Phosphorylation	ESQSQKRSLHSVSEE CCHHHHHHHHHCCHH	37.15	25159151
2063	Phosphorylation	SQKRSLHSVSEERTD HHHHHHHHCCHHHHH	32.41	23401153
2065	Phosphorylation	KRSLHSVSEERTDEM HHHHHHCCHHHHHHC	36.43	30108239
2069	Phosphorylation	HSVSEERTDEMTHKE HHCCHHHHHHCCCHH	39.32	18669648
2072	Phosphorylation	SEERTDEMTHKETNE CHHHHHHCCCHHCCH	5.46	-
2073	Phosphorylation	EERTDEMTHKETNEQ HHHHHHCCCHHCCHH	27.96	23312004
2074	Phosphorylation	ERTDEMTHKETNEQE HHHHHCCCHHCCHHH	25.33	-
2075	Acetylation	RTDEMTHKETNEQEE HHHHCCCHHCCHHHH	58.00	26051181
2087	Phosphorylation	QEERLLATASFTKSS HHHHHHHHHHHCCCC	23.86	25159151
2089	Phosphorylation	ERLLATASFTKSSRS HHHHHHHHHCCCCCC	29.15	25159151
2091	Phosphorylation	LLATASFTKSSRSSR HHHHHHHCCCCCCCC	27.76	25159151
2092	Acetylation	LATASFTKSSRSSRT HHHHHHCCCCCCCCC	44.41	26051181
2092	Methylation	LATASFTKSSRSSRT HHHHHHCCCCCCCCC	44.41	-
2093	Phosphorylation	ATASFTKSSRSSRTR HHHHHCCCCCCCCCC	28.11	29214152
2096	Phosphorylation	SFTKSSRSSRTRSSK HHCCCCCCCCCCCCC	26.56	20068231
2098	Phosphorylation	TKSSRSSRTRSSKAI CCCCCCCCCCCCCEE	35.09	18669648
2100	Phosphorylation	SSRSSRTRSSKAILL CCCCCCCCCCCEEEC	37.51	-
2101	Methylation	SRSSRTRSSKAILLP CCCCCCCCCCEEECC	35.26	-
2102	Phosphorylation	RSSRTRSSKAILLPD CCCCCCCCCEEECCC	23.86	-
2111	Phosphorylation	AILLPDLSEPNNEPL EEECCCCCCCCCCCC	59.39	24732914
2120	Phosphorylation	PNNEPLFSPASEVPR CCCCCCCCCHHHCCC	27.52	25159151
2123	Phosphorylation	EPLFSPASEVPRKAK CCCCCCHHHCCCCCC	42.38	25159151
2129	Phosphorylation	ASEVPRKAKAKKIEV HHHCCCCCCCCCCCC	20.51	18669648
2132	Phosphorylation	VPRKAKAKKIEVPAQ CCCCCCCCCCCCCHH	54.28	18669648
2145	Phosphorylation	AQLKELVSDLSSQFV HHHHHHHHHHHHCCC	45.52	28192239
2148	Phosphorylation	KELVSDLSSQFVISP HHHHHHHHHCCCCCC	27.38	28192239
2149	Phosphorylation	ELVSDLSSQFVISPP HHHHHHHHCCCCCCH	34.63	28102081
2154	Phosphorylation	LSSQFVISPPALRSR HHHCCCCCCHHHHHC	21.38	25159151
2160	Phosphorylation	ISPPALRSRQKNTSN CCCHHHHHCCCCCCC	39.66	21712546
2163	Phosphorylation	PALRSRQKNTSNKNK HHHHHCCCCCCCCCH	62.17	18669648
2169	Phosphorylation	QKNTSNKNKLEDELK CCCCCCCCHHHHHHH	59.40	-
2176	Acetylation	NKLEDELKDDAQSVE CHHHHHHHHHHHHHH	52.06	26051181
2181	Phosphorylation	ELKDDAQSVETLGKP HHHHHHHHHHHHCCC	24.52	29255136
2184	Phosphorylation	DDAQSVETLGKPKAK HHHHHHHHHCCCCHH	38.36	29255136
2187	Acetylation	QSVETLGKPKAKRIR HHHHHHCCCCHHHCC	46.59	26051181
2190	Phosphorylation	ETLGKPKAKRIRTSK HHHCCCCHHHCCCCC	18.19	-
2205	Phosphorylation	TKQASKNTEKESAWS CCCCCCCCCCCCCCC	52.77	28464451
2207	Ubiquitination	QASKNTEKESAWSPP CCCCCCCCCCCCCCC	55.73	29967540
2209	Phosphorylation	SKNTEKESAWSPPPI CCCCCCCCCCCCCCE	46.21	30266825
2212	Phosphorylation	TEKESAWSPPPIEIR CCCCCCCCCCCEEEE	27.52	30266825
2216	Ubiquitination	SAWSPPPIEIRLISP CCCCCCCEEEEEECC	9.42	29967540
2221	Phosphorylation	PPIEIRLISPLASPA CCEEEEEECCCCCCC	2.61	18669648
2222	Phosphorylation	PIEIRLISPLASPAD CEEEEEECCCCCCCC	20.60	29255136
2226	Phosphorylation	RLISPLASPADGVKS EEECCCCCCCCCCCC	28.44	29255136
2231	Phosphorylation	LASPADGVKSKPRKT CCCCCCCCCCCCCCC	6.96	18669648
2233	Phosphorylation	SPADGVKSKPRKTTE CCCCCCCCCCCCCEE	45.55	21712546
2235	Phosphorylation	ADGVKSKPRKTTEVT CCCCCCCCCCCEECC	50.52	18669648
2238	Phosphorylation	VKSKPRKTTEVTGTG CCCCCCCCEECCCCC	29.48	19060867
2239	Phosphorylation	KSKPRKTTEVTGTGL CCCCCCCEECCCCCC	31.34	28555341
2242	Phosphorylation	PRKTTEVTGTGLGRN CCCCEECCCCCCCCC	23.85	19060867
2244	Phosphorylation	KTTEVTGTGLGRNRK CCEECCCCCCCCCHH	21.62	28555341
2254	Phosphorylation	GRNRKKLSSYPKQIL CCCHHHHHHCHHHHH	36.38	18491316
2255	Phosphorylation	RNRKKLSSYPKQILR CCHHHHHHCHHHHHH	56.76	24719451
2263	Phosphorylation	YPKQILRRKML---- CHHHHHHHHCC----	25.87	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ELYS_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ELYS_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ELYS_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NU160_HUMAN	NUP160	physical	22955883

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1017, AND MASS SPECTROMETRY.
PubMed: 19608861

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1283; SER-1541;SER-1878; SER-1884; SER-2222 AND SER-2226, AND MASS SPECTROMETRY.
PubMed: 19690332

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-528; SER-1142; SER-1150;SER-1155; SER-1160; THR-1175; SER-1232; SER-1250; THR-1257; SER-1283;SER-1541; SER-1729; SER-1806; THR-1808; SER-1878; SER-1884; SER-1898;SER-2060; SER-2089; SER-2120; SER-2123; SER-2154; SER-2212; SER-2222AND SER-2226, AND MASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-528; SER-1216; SER-1218;SER-1222; THR-1808 AND SER-1944, AND MASS SPECTROMETRY.
PubMed: 18220336

"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1160; SER-1232;SER-1402; SER-1511; THR-1620; SER-1692; SER-1737; THR-1764; SER-1771;SER-1898; SER-1944; SER-1952; SER-2060; SER-2063; SER-2222; SER-2226;THR-2238; THR-2242 AND SER-2254, AND MASS SPECTROMETRY.
PubMed: 19007248

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1283 AND SER-1295, ANDMASS SPECTROMETRY.
PubMed: 17525332

"Phosphoproteome analysis of the human mitotic spindle.";
Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.;
Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-528; SER-1087; SER-1232;SER-1283; SER-1513; SER-1541; SER-2212 AND SER-2222, AND MASSSPECTROMETRY.
PubMed: 16565220

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2222 AND SER-2226, ANDMASS SPECTROMETRY.
PubMed: 16964243

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1232; SER-1283;SER-1513; SER-1541; SER-1996; SER-2222 AND SER-2226, AND MASSSPECTROMETRY.
PubMed: 17081983