dbPTM

HTF4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HTF4_HUMAN
UniProt AC	Q99081
Protein Name	Transcription factor 12
Gene Name	TCF12
Organism	Homo sapiens (Human).
Sequence Length	682
Subcellular Localization	Nucleus.
Protein Description	Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3')..
Protein Sequence	MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	QRMAAIGTDKELSDL HHHHHHCCCHHHHHH	37.47	-
24	Phosphorylation	LSDLLDFSAMFSPPV HHHHHCHHHHCCCCC	20.63	26074081
28	Phosphorylation	LDFSAMFSPPVNSGK HCHHHHCCCCCCCCC	18.40	22199227
28 (in isoform 2)	Phosphorylation	-	18.40	27732954
31 (in isoform 2)	Phosphorylation	-	11.48	27732954
33	Phosphorylation	MFSPPVNSGKTRPTT HCCCCCCCCCCCCCC	41.73	26074081
35	Ubiquitination	SPPVNSGKTRPTTLG CCCCCCCCCCCCCCC	40.98	-
36	Phosphorylation	PPVNSGKTRPTTLGS CCCCCCCCCCCCCCC	45.46	28985074
39	Phosphorylation	NSGKTRPTTLGSSQF CCCCCCCCCCCCCCC	31.21	26074081
40	Phosphorylation	SGKTRPTTLGSSQFS CCCCCCCCCCCCCCC	31.63	26074081
43	Phosphorylation	TRPTTLGSSQFSGSG CCCCCCCCCCCCCCC	24.87	22199227
44	Phosphorylation	RPTTLGSSQFSGSGI CCCCCCCCCCCCCCC	33.18	22199227
47	Phosphorylation	TLGSSQFSGSGIDER CCCCCCCCCCCCCCC	25.14	25159151
49	Phosphorylation	GSSQFSGSGIDERGG CCCCCCCCCCCCCCC	31.23	28450419
57	Phosphorylation	GIDERGGTTSWGTSG CCCCCCCCCCCCCCC	22.08	23401153
58	Phosphorylation	IDERGGTTSWGTSGQ CCCCCCCCCCCCCCC	26.25	22167270
59	Phosphorylation	DERGGTTSWGTSGQP CCCCCCCCCCCCCCC	24.28	22167270
62	Phosphorylation	GGTTSWGTSGQPSPS CCCCCCCCCCCCCCC	24.35	30266825
63	Phosphorylation	GTTSWGTSGQPSPSY CCCCCCCCCCCCCCC	31.34	30266825
67	Phosphorylation	WGTSGQPSPSYDSSR CCCCCCCCCCCCCCC	20.70	19664994
69	Phosphorylation	TSGQPSPSYDSSRGF CCCCCCCCCCCCCCC	46.00	30266825
70	Phosphorylation	SGQPSPSYDSSRGFT CCCCCCCCCCCCCCC	24.19	30266825
72	Phosphorylation	QPSPSYDSSRGFTDS CCCCCCCCCCCCCCC	17.44	22167270
73	Phosphorylation	PSPSYDSSRGFTDSP CCCCCCCCCCCCCCC	33.26	22167270
77	Phosphorylation	YDSSRGFTDSPHYSD CCCCCCCCCCCCCHH	38.09	23401153
79	Phosphorylation	SSRGFTDSPHYSDHL CCCCCCCCCCCHHCC	15.54	23401153
82	Phosphorylation	GFTDSPHYSDHLNDS CCCCCCCCHHCCCCC	21.12	29255136
83	Phosphorylation	FTDSPHYSDHLNDSR CCCCCCCHHCCCCCC	18.60	29255136
89	Phosphorylation	YSDHLNDSRLGAHEG CHHCCCCCCCCCCCC	28.47	23927012
98	Phosphorylation	LGAHEGLSPTPFMNS CCCCCCCCCCCCCCC	37.27	23401153
100	Phosphorylation	AHEGLSPTPFMNSNL CCCCCCCCCCCCCCC	26.28	30266825
105	Phosphorylation	SPTPFMNSNLMGKTS CCCCCCCCCCCCCCC	21.39	23403867
110	Sumoylation	MNSNLMGKTSERGSF CCCCCCCCCCCCCCE	34.61	28112733
110	Ubiquitination	MNSNLMGKTSERGSF CCCCCCCCCCCCCCE	34.61	-
110 (in isoform 3)	Ubiquitination	-	34.61	-
111	Phosphorylation	NSNLMGKTSERGSFS CCCCCCCCCCCCCEE	30.05	21712546
112	Phosphorylation	SNLMGKTSERGSFSL CCCCCCCCCCCCEEE	28.87	23186163
114	Methylation	LMGKTSERGSFSLYS CCCCCCCCCCEEEEE	45.91	115388229
116	Phosphorylation	GKTSERGSFSLYSRD CCCCCCCCEEEEECC	20.20	23401153
118	Phosphorylation	TSERGSFSLYSRDTG CCCCCCEEEEECCCC	28.26	28555341
120	Phosphorylation	ERGSFSLYSRDTGLP CCCCEEEEECCCCCC	10.64	27642862
121	Phosphorylation	RGSFSLYSRDTGLPG CCCEEEEECCCCCCC	29.04	24719451
124	Phosphorylation	FSLYSRDTGLPGCQS EEEEECCCCCCCHHH	39.24	26434776
131	Phosphorylation	TGLPGCQSSLLRQDL CCCCCHHHHHHHHHC	27.34	26434776
132	Phosphorylation	GLPGCQSSLLRQDLG CCCCHHHHHHHHHCC	12.92	26434776
142	Phosphorylation	RQDLGLGSPAQLSSS HHHCCCCCHHHHHCC	23.31	23401153
147	Phosphorylation	LGSPAQLSSSGKPGT CCCHHHHHCCCCCCE	15.46	27732954
148	Phosphorylation	GSPAQLSSSGKPGTA CCHHHHHCCCCCCEE	52.26	27732954
149	Phosphorylation	SPAQLSSSGKPGTAY CHHHHHCCCCCCEEE	47.67	27732954
151	Acetylation	AQLSSSGKPGTAYYS HHHHCCCCCCEEEEE	42.07	26051181
151	Ubiquitination	AQLSSSGKPGTAYYS HHHHCCCCCCEEEEE	42.07	-
151 (in isoform 3)	Ubiquitination	-	42.07	-
156	Phosphorylation	SGKPGTAYYSFSATS CCCCCEEEEEEECCC	10.24	-
157	Phosphorylation	GKPGTAYYSFSATSS CCCCEEEEEEECCCC	10.77	-
163	Phosphorylation	YYSFSATSSRRRPLH EEEEECCCCCCCCCC	22.89	17525332
164	Phosphorylation	YSFSATSSRRRPLHD EEEECCCCCCCCCCC	26.00	24850871
172	Phosphorylation	RRRPLHDSAALDPLQ CCCCCCCCCCCCHHH	12.51	28555341
181	Acetylation	ALDPLQAKKVRKVPP CCCHHHHHHCCCCCC	38.55	25953088
181	Sumoylation	ALDPLQAKKVRKVPP CCCHHHHHHCCCCCC	38.55	28112733
181	Ubiquitination	ALDPLQAKKVRKVPP CCCHHHHHHCCCCCC	38.55	-
185	Ubiquitination	LQAKKVRKVPPGLPS HHHHHCCCCCCCCCC	63.18	-
192	O-linked_Glycosylation	KVPPGLPSSVYAPSP CCCCCCCCCCCCCCC	37.16	31492838
192	Phosphorylation	KVPPGLPSSVYAPSP CCCCCCCCCCCCCCC	37.16	26074081
193	Phosphorylation	VPPGLPSSVYAPSPN CCCCCCCCCCCCCCC	19.73	26074081
195	Phosphorylation	PGLPSSVYAPSPNSD CCCCCCCCCCCCCCC	18.10	26074081
198	Phosphorylation	PSSVYAPSPNSDDFN CCCCCCCCCCCCCCC	28.65	30576142
201	Phosphorylation	VYAPSPNSDDFNRES CCCCCCCCCCCCCCC	41.77	26074081
208	Phosphorylation	SDDFNRESPSYPSPK CCCCCCCCCCCCCCC	18.86	26074081
210	Phosphorylation	DFNRESPSYPSPKPP CCCCCCCCCCCCCCC	59.98	26074081
211	Phosphorylation	FNRESPSYPSPKPPT CCCCCCCCCCCCCCC	15.89	26074081
213	Phosphorylation	RESPSYPSPKPPTSM CCCCCCCCCCCCCCC	37.00	26074081
218	Phosphorylation	YPSPKPPTSMFASTF CCCCCCCCCCCEEEE	41.15	26074081
219	Phosphorylation	PSPKPPTSMFASTFF CCCCCCCCCCEEEEE	20.06	26074081
223	Phosphorylation	PPTSMFASTFFMQDG CCCCCCEEEEEECCC	17.93	26074081
224	Phosphorylation	PTSMFASTFFMQDGT CCCCCEEEEEECCCC	19.91	26074081
239	Phosphorylation	HNSSDLWSSSNGMSQ CCCHHHHHCCCCCCC	31.05	26074081
240	Phosphorylation	NSSDLWSSSNGMSQP CCHHHHHCCCCCCCC	19.08	26074081
241	Phosphorylation	SSDLWSSSNGMSQPG CHHHHHCCCCCCCCC	31.71	26074081
245	Phosphorylation	WSSSNGMSQPGFGGI HHCCCCCCCCCCCCC	34.32	26074081
255	Phosphorylation	GFGGILGTSTSHMSQ CCCCCCCCCCCCCCC	25.94	26074081
256	Phosphorylation	FGGILGTSTSHMSQS CCCCCCCCCCCCCCC	26.56	26074081
257	Phosphorylation	GGILGTSTSHMSQSS CCCCCCCCCCCCCCC	23.61	26074081
258	Phosphorylation	GILGTSTSHMSQSSS CCCCCCCCCCCCCCC	19.57	26074081
261	Phosphorylation	GTSTSHMSQSSSYGN CCCCCCCCCCCCCCC	22.83	26074081
263	Phosphorylation	STSHMSQSSSYGNLH CCCCCCCCCCCCCCC	17.59	26074081
264	Phosphorylation	TSHMSQSSSYGNLHS CCCCCCCCCCCCCCC	21.68	26074081
265	Phosphorylation	SHMSQSSSYGNLHSH CCCCCCCCCCCCCCC	42.16	26074081
266	Phosphorylation	HMSQSSSYGNLHSHD CCCCCCCCCCCCCCC	16.39	26074081
271	Phosphorylation	SSYGNLHSHDRLSYP CCCCCCCCCCCCCCC	30.19	26074081
276	Phosphorylation	LHSHDRLSYPPHSVS CCCCCCCCCCCCCCC	36.17	23401153
277	Phosphorylation	HSHDRLSYPPHSVSP CCCCCCCCCCCCCCC	25.94	25159151
281	O-linked_Glycosylation	RLSYPPHSVSPTDIN CCCCCCCCCCCCCCC	30.02	31492838
281	Phosphorylation	RLSYPPHSVSPTDIN CCCCCCCCCCCCCCC	30.02	23401153
283	Phosphorylation	SYPPHSVSPTDINTS CCCCCCCCCCCCCCC	25.71	23401153
285	Phosphorylation	PPHSVSPTDINTSLP CCCCCCCCCCCCCCC	41.84	22115753
289	Phosphorylation	VSPTDINTSLPPMSS CCCCCCCCCCCCCCC	31.79	28464451
290	Phosphorylation	SPTDINTSLPPMSSF CCCCCCCCCCCCCCC	34.10	28464451
295	Phosphorylation	NTSLPPMSSFHRGST CCCCCCCCCCCCCCC	35.31	26074081
296	Phosphorylation	TSLPPMSSFHRGSTS CCCCCCCCCCCCCCC	20.86	26074081
301	Phosphorylation	MSSFHRGSTSSSPYV CCCCCCCCCCCCCCE	25.69	23403867
302	Phosphorylation	SSFHRGSTSSSPYVA CCCCCCCCCCCCCEE	35.14	23401153
303	Phosphorylation	SFHRGSTSSSPYVAA CCCCCCCCCCCCEEC	30.43	21712546
304	Phosphorylation	FHRGSTSSSPYVAAS CCCCCCCCCCCEECC	35.11	21712546
305	Phosphorylation	HRGSTSSSPYVAASH CCCCCCCCCCEECCC	21.73	25159151
307	Phosphorylation	GSTSSSPYVAASHTP CCCCCCCCEECCCCC	12.50	21712546
311	O-linked_Glycosylation	SSPYVAASHTPPING CCCCEECCCCCCCCC	20.39	31492838
311	Phosphorylation	SSPYVAASHTPPING CCCCEECCCCCCCCC	20.39	23401153
313	Phosphorylation	PYVAASHTPPINGSD CCEECCCCCCCCCCC	28.41	23401153
319	Phosphorylation	HTPPINGSDSILGTR CCCCCCCCCCCCCCC	24.56	21712546
321	Phosphorylation	PPINGSDSILGTRGN CCCCCCCCCCCCCCC	22.78	21712546
325	Phosphorylation	GSDSILGTRGNAAGS CCCCCCCCCCCCCCC	31.77	23403867
332	Phosphorylation	TRGNAAGSSQTGDAL CCCCCCCCCHHHHHH	17.97	25159151
333	Phosphorylation	RGNAAGSSQTGDALG CCCCCCCCHHHHHHH	30.73	17525332
335	Phosphorylation	NAAGSSQTGDALGKA CCCCCCHHHHHHHHH	38.69	21712546
345	Phosphorylation	ALGKALASIYSPDHT HHHHHHHHHCCCCCC	23.94	26074081
345 (in isoform 3)	Phosphorylation	-	23.94	25921289
347	Phosphorylation	GKALASIYSPDHTSS HHHHHHHCCCCCCCC	16.20	26074081
348	Phosphorylation	KALASIYSPDHTSSS HHHHHHCCCCCCCCC	23.37	30576142
352	Phosphorylation	SIYSPDHTSSSFPSN HHCCCCCCCCCCCCC	37.37	26074081
353	Phosphorylation	IYSPDHTSSSFPSNP HCCCCCCCCCCCCCC	22.14	26074081
354	Phosphorylation	YSPDHTSSSFPSNPS CCCCCCCCCCCCCCC	36.83	26074081
355	Phosphorylation	SPDHTSSSFPSNPST CCCCCCCCCCCCCCC	40.73	26074081
358	Phosphorylation	HTSSSFPSNPSTPVG CCCCCCCCCCCCCCC	60.40	26074081
358 (in isoform 3)	Phosphorylation	-	60.40	25921289
361	Phosphorylation	SSFPSNPSTPVGSPS CCCCCCCCCCCCCCC	49.98	26074081
361 (in isoform 3)	Phosphorylation	-	49.98	25921289
362	Phosphorylation	SFPSNPSTPVGSPSP CCCCCCCCCCCCCCC	24.21	28122231
362 (in isoform 3)	Phosphorylation	-	24.21	25921289
366	Phosphorylation	NPSTPVGSPSPLTGT CCCCCCCCCCCCCCC	23.57	25921289
366 (in isoform 3)	Phosphorylation	-	23.57	25921289
368	Phosphorylation	STPVGSPSPLTGTSQ CCCCCCCCCCCCCCC	33.95	28122231
368 (in isoform 3)	Phosphorylation	-	33.95	25921289
371	Phosphorylation	VGSPSPLTGTSQWPR CCCCCCCCCCCCCCC	41.62	28464451
373	Phosphorylation	SPSPLTGTSQWPRPG CCCCCCCCCCCCCCC	16.71	30576142
374	Phosphorylation	PSPLTGTSQWPRPGG CCCCCCCCCCCCCCC	31.43	28122231
385	Phosphorylation	RPGGQAPSSPSYENS CCCCCCCCCCCHHHH	58.87	22167270
385 (in isoform 3)	Phosphorylation	-	58.87	28796482
386	Phosphorylation	PGGQAPSSPSYENSL CCCCCCCCCCHHHHH	19.46	23401153
386 (in isoform 3)	Phosphorylation	-	19.46	28796482
388	Phosphorylation	GQAPSSPSYENSLHS CCCCCCCCHHHHHHH	47.21	22167270
388 (in isoform 3)	Phosphorylation	-	47.21	28796482
389	Phosphorylation	QAPSSPSYENSLHSL CCCCCCCHHHHHHHH	23.63	28122231
389 (in isoform 3)	Phosphorylation	-	23.63	28796482
392	Phosphorylation	SSPSYENSLHSLQSR CCCCHHHHHHHHHHH	18.60	23401153
392 (in isoform 3)	Phosphorylation	-	18.60	28796482
395	Phosphorylation	SYENSLHSLQSRMED CHHHHHHHHHHHHHH	33.14	23663014
395 (in isoform 3)	Phosphorylation	-	33.14	27732954
397	Ubiquitination	ENSLHSLQSRMEDRL HHHHHHHHHHHHHHH	31.82	-
398	Phosphorylation	NSLHSLQSRMEDRLD HHHHHHHHHHHHHHH	38.60	23663014
416 (in isoform 3)	Ubiquitination	-	24.25	-
462	Phosphorylation	SLVASSRSASMVGTH HHHEECCCCCCCCCC	27.00	27732954
464	Phosphorylation	VASSRSASMVGTHRE HEECCCCCCCCCCCC	18.43	27732954
473	Phosphorylation	VGTHREDSVSLNGNH CCCCCCCCEECCCCC	14.62	-
488	Phosphorylation	SVLSSTVTTSSTDLN CEEEEEEEECCCCCC	22.50	-
490	Phosphorylation	LSSTVTTSSTDLNHK EEEEEEECCCCCCCC	23.13	-
497	Acetylation	SSTDLNHKTQENYRG CCCCCCCCCCCCCCC	51.32	25953088
503	Methylation	HKTQENYRGGLQSQS CCCCCCCCCCCCCCC	44.26	115388237
508	Phosphorylation	NYRGGLQSQSGTVVT CCCCCCCCCCCCEEE	31.21	28555341
510	Phosphorylation	RGGLQSQSGTVVTTE CCCCCCCCCCEEEEE	41.50	28555341
512	Phosphorylation	GLQSQSGTVVTTEIK CCCCCCCCEEEEEEE	19.63	28555341
519	Sumoylation	TVVTTEIKTENKEKD CEEEEEEECCCCHHC	43.48	-
519	Sumoylation	TVVTTEIKTENKEKD CEEEEEEECCCCHHC	43.48	28112733
534	Phosphorylation	ENLHEPPSSDDMKSD CCCCCCCCCHHCCCC	58.05	21955146
535	Phosphorylation	NLHEPPSSDDMKSDD CCCCCCCCHHCCCCC	43.32	21955146
540	Phosphorylation	PSSDDMKSDDESSQK CCCHHCCCCCHHHHH	43.59	23401153
544	Phosphorylation	DMKSDDESSQKDIKV HCCCCCHHHHHCEEE	45.09	21955146
545	Phosphorylation	MKSDDESSQKDIKVS CCCCCHHHHHCEEEE	38.92	21955146
550	Sumoylation	ESSQKDIKVSSRGRT HHHHHCEEEECCCCC	46.31	-
550	Sumoylation	ESSQKDIKVSSRGRT HHHHHCEEEECCCCC	46.31	25218447
550	Ubiquitination	ESSQKDIKVSSRGRT HHHHHCEEEECCCCC	46.31	-
552	Phosphorylation	SQKDIKVSSRGRTSS HHHCEEEECCCCCCC	14.87	20068231
553	Phosphorylation	QKDIKVSSRGRTSST HHCEEEECCCCCCCC	41.56	20068231
557	Phosphorylation	KVSSRGRTSSTNEDE EEECCCCCCCCCCCC	29.83	22167270
558	Phosphorylation	VSSRGRTSSTNEDED EECCCCCCCCCCCCC	33.53	22167270
559	Phosphorylation	SSRGRTSSTNEDEDL ECCCCCCCCCCCCCC	34.34	22167270
560	Phosphorylation	SRGRTSSTNEDEDLN CCCCCCCCCCCCCCC	42.25	23927012
564	Phosphorylation	TSSTNEDEDLNPEQK CCCCCCCCCCCHHHH	59.21	27251275
571	Ubiquitination	EDLNPEQKIEREKER CCCCHHHHHHHHHHH	44.89	-
576	Phosphorylation	EQKIEREKERRMANN HHHHHHHHHHHHHHH	63.84	-
581	Phosphorylation	REKERRMANNARERL HHHHHHHHHHHHHHH	12.33	24719451
582	Phosphorylation	EKERRMANNARERLR HHHHHHHHHHHHHHH	33.09	24719451
583	Phosphorylation	KERRMANNARERLRV HHHHHHHHHHHHHHH	30.73	27251275
595 (in isoform 3)	Ubiquitination	-	56.68	-
598	Ubiquitination	RDINEAFKELGRMCQ HHHHHHHHHHHHHHH	60.11	-
609	Sumoylation	RMCQLHLKSEKPQTK HHHHHHHCCCCCCCE	45.91	28112733
609	Ubiquitination	RMCQLHLKSEKPQTK HHHHHHHCCCCCCCE	45.91	-
610	Phosphorylation	MCQLHLKSEKPQTKL HHHHHHCCCCCCCEE	58.16	-
612	Ubiquitination	QLHLKSEKPQTKLLI HHHHCCCCCCCEEHH	49.90	-
622 (in isoform 3)	Ubiquitination	-	33.80	-
642	Ubiquitination	RERNLNPKAACLKRR HHCCCCHHHHHHHHC	47.76	-
653	Sumoylation	LKRREEEKVSAVSAE HHHCHHHHCCCEECC	44.78	28112733
653	Ubiquitination	LKRREEEKVSAVSAE HHHCHHHHCCCEECC	44.78	-
666 (in isoform 3)	Ubiquitination	-	43.47	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HTF4_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HTF4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HTF4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ASCL4_HUMAN	ASCL4	physical	14516699
TCF23_HUMAN	TCF23	physical	14516699
OLIG3_HUMAN	OLIG3	physical	14516699
MTG8_HUMAN	RUNX1T1	physical	15333839
CBP_HUMAN	CREBBP	physical	15333839
EP300_HUMAN	EP300	physical	15333839
TAF4_HUMAN	TAF4	physical	15333839
TBP_HUMAN	TBP	physical	15333839
SMAD2_HUMAN	SMAD2	physical	21828274
SMAD3_HUMAN	SMAD3	physical	21828274
TFE2_HUMAN	TCF3	physical	21828274
FOXH1_HUMAN	FOXH1	physical	21828274
TCF21_HUMAN	TCF21	physical	21771727
TSNAX_HUMAN	TSNAX	physical	25416956
STK16_HUMAN	STK16	physical	25416956
MABP1_HUMAN	MAPKBP1	physical	25416956
ARMC8_HUMAN	ARMC8	physical	25416956
EDRF1_HUMAN	EDRF1	physical	25416956
RPC9_HUMAN	CRCP	physical	25416956
OSGI1_HUMAN	OSGIN1	physical	25416956
NGN3_HUMAN	NEUROG3	physical	25416956
VPS28_HUMAN	VPS28	physical	25416956
SPG21_HUMAN	SPG21	physical	25416956
CA109_HUMAN	C1orf109	physical	25416956
NAGK_HUMAN	NAGK	physical	25416956
HOP_HUMAN	HOPX	physical	25416956
CP045_HUMAN	C16orf45	physical	25416956
TWST2_HUMAN	TWIST2	physical	25416956
MORN4_HUMAN	MORN4	physical	25416956
ASCL4_HUMAN	ASCL4	physical	25416956
HEXI2_HUMAN	HEXIM2	physical	25416956
CF206_HUMAN	C6orf165	physical	25416956
LYSM1_HUMAN	LYSMD1	physical	25416956
TRI72_HUMAN	TRIM72	physical	25416956
HTF4_HUMAN	TCF12	physical	9050988

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
615314	Craniosynostosis 3 (CRS3)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HTF4_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-67; SER-333 AND THR-557,AND MASS SPECTROMETRY.	19690332 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305 AND THR-313, ANDMASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-44 AND SER-47, AND MASSSPECTROMETRY.	18220336 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-333, AND MASSSPECTROMETRY.	17525332 [Abstract]