dbPTM

CAH5B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CAH5B_HUMAN
UniProt AC	Q9Y2D0
Protein Name	Carbonic anhydrase 5B, mitochondrial
Gene Name	CA5B
Organism	Homo sapiens (Human).
Sequence Length	317
Subcellular Localization	Mitochondrion.
Protein Description	Reversible hydration of carbon dioxide..
Protein Sequence	MVVMNSLRVILQASPGKLLWRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVDLVPGGDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVIGVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDYVLNVQAKPKPATSQATP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MVVMNSLRVILQA --CCCCCCCEEHHHC	10.23	24247654
54	Phosphorylation	ALHPLWESVDLVPGG CCCCCCEEEEECCCC	14.89	25002506
116	Ubiquitination	STDKSVIKGGPLEHN CCCCCCEECCCCCCC	56.51	-
202	Phosphorylation	KLVDTLPSIKHKDAL HHHHHCHHHCCCHHE	47.59	24719451
249	Ubiquitination	SVTWIIKKQPVEVDH CEEEEEECCCCCCCH	49.80	-
249	Malonylation	SVTWIIKKQPVEVDH CEEEEEECCCCCCCH	49.80	26320211
249	Succinylation	SVTWIIKKQPVEVDH CEEEEEECCCCCCCH	49.80	27452117
273	Ubiquitination	LFTSEGEKEKRMVDN HHCCCCHHHHHHHCC	78.41	-
295	Phosphorylation	MNRTVRSSFRHDYVL CCHHHHHHCCCCEEE	18.74	17081983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CAH5B_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CAH5B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CAH5B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ODB2_HUMAN	DBT	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CAH5B_HUMAN

Related Literatures of Post-Translational Modification