| UniProt ID | CADM4_HUMAN | |
|---|---|---|
| UniProt AC | Q8NFZ8 | |
| Protein Name | Cell adhesion molecule 4 | |
| Gene Name | CADM4 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 388 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein . |
|
| Protein Description | Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.. | |
| Protein Sequence | MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLNGSDGHKRKEEFFI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 31 | N-linked_Glycosylation | GQEVQTENVTVAEGG CCEEEEECEEEEECC | 37.84 | UniProtKB CARBOHYD | |
| 63 | Phosphorylation | IQNPARQTLFFNGTR EECCCCCEEEECCCC | 21.71 | - | |
| 67 | N-linked_Glycosylation | ARQTLFFNGTRALKD CCCEEEECCCCCCCC | 43.52 | UniProtKB CARBOHYD | |
| 67 | N-linked_Glycosylation | ARQTLFFNGTRALKD CCCEEEECCCCCCCC | 43.52 | 19349973 | |
| 69 | Phosphorylation | QTLFFNGTRALKDER CEEEECCCCCCCCCC | 17.55 | - | |
| 83 | Phosphorylation | RFQLEEFSPRRVRIR CCCCCCCCCCEEEEE | 22.30 | 23401153 | |
| 223 | Phosphorylation | YVLDVQYSPTARIHA EEEEEEECCCCEEEE | 9.93 | - | |
| 262 | N-linked_Glycosylation | QIRWNRGNESLPERA CCCCCCCCCCHHHHH | 32.23 | - | |
| 262 | N-linked_Glycosylation | QIRWNRGNESLPERA CCCCCCCCCCHHHHH | 32.23 | 19349973 | |
| 286 | N-linked_Glycosylation | PGLVSADNGTYTCEA CCEEECCCCEEEEEE | 44.41 | UniProtKB CARBOHYD | |
| 352 | Ubiquitination | VWCSVRQKGSYLTHE HHHHHHCCCCEECCC | 38.98 | 32142685 | |
| 354 | Phosphorylation | CSVRQKGSYLTHEAS HHHHCCCCEECCCCC | 24.81 | 22496350 | |
| 355 | Phosphorylation | SVRQKGSYLTHEASG HHHCCCCEECCCCCC | 25.04 | 28857561 | |
| 357 | Phosphorylation | RQKGSYLTHEASGLD HCCCCEECCCCCCCC | 14.94 | 27251789 | |
| 361 | Phosphorylation | SYLTHEASGLDEQGE CEECCCCCCCCCCCH | 36.58 | 30266825 | |
| 377 | Phosphorylation | REAFLNGSDGHKRKE HHHHHCCCCCCCCCH | 39.07 | 30266825 | |
| 381 | Ubiquitination | LNGSDGHKRKEEFFI HCCCCCCCCCHHCCC | 71.36 | 33845483 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CADM4_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CADM4_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CADM4_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CADM4_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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