KI21A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KI21A_HUMAN
• UniProt AC: Q7Z4S6
• Protein Name: Kinesin-like protein KIF21A
• Gene Name: KIF21A
• Organism: Homo sapiens (Human).
• Sequence Length: 1674
• Subcellular Localization: Cytoplasm, cytoskeleton .
• Protein Description: Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-end directed motor activity (By similarity)..
• Protein Sequence: MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MLGAPDES -------CCCCCCCH	35.87	22223895
8	Phosphorylation	MLGAPDESSVRVAVR CCCCCCCHHCEEEEE	41.32	23663014
9	Phosphorylation	LGAPDESSVRVAVRI CCCCCCHHCEEEEEC	16.34	23663014
22	Ubiquitination	RIRPQLAKEKIEGCH ECCHHHHHHCCCCCE	69.04	29967540
45	Ubiquitination	EPQVFLGKDKAFTFD CCEEEECCCCEEEEE	59.19	29967540
47	Ubiquitination	QVFLGKDKAFTFDYV EEEECCCCEEEEEEE	49.22	-
50	Phosphorylation	LGKDKAFTFDYVFDI ECCCCEEEEEEEEEC	22.06	27067055
65	Phosphorylation	DSQQEQIYIQCIEKL CCCHHHHHHHHHHHH	5.66	27067055
123	Ubiquitination	RAVKHLFKSIEEKKH HHHHHHHHHHHHHHC	57.81	29967540
181	Phosphorylation	NIRIHEDSTGGIYTV CEEEEECCCCCEEEE	26.43	21945579
182	Phosphorylation	IRIHEDSTGGIYTVG EEEEECCCCCEEEEE	52.31	21945579
186	Phosphorylation	EDSTGGIYTVGVTTR ECCCCCEEEEEEEEC	9.92	21945579
187	Phosphorylation	DSTGGIYTVGVTTRT CCCCCEEEEEEEECE	14.63	21945579
206	Ubiquitination	SEMMQCLKLGALSRT HHHHHHHHHCCCCCC	53.12	-
211	Phosphorylation	CLKLGALSRTTASTQ HHHHCCCCCCCCCCC	27.35	29759185
213	Phosphorylation	KLGALSRTTASTQMN HHCCCCCCCCCCCCC	24.28	21406692
214	Phosphorylation	LGALSRTTASTQMNV HCCCCCCCCCCCCCC	19.94	21406692
216	Phosphorylation	ALSRTTASTQMNVQS CCCCCCCCCCCCCCC	19.65	21406692
217	Phosphorylation	LSRTTASTQMNVQSS CCCCCCCCCCCCCCC	29.40	21406692
223	Phosphorylation	STQMNVQSSRSHAIF CCCCCCCCCCCCEEE	24.36	29116813
224	Phosphorylation	TQMNVQSSRSHAIFT CCCCCCCCCCCEEEE	22.25	29978859
292	Ubiquitination	GATGERAKEGISINC CCCCCHHHCCCEECH	63.80	-
314	Ubiquitination	VISALGDKSKRATHV HHHHCCCCCCCCCCC	56.96	-
323	Phosphorylation	KRATHVPYRDSKLTR CCCCCCCCCHHHHHH	26.43	27732954
326	Phosphorylation	THVPYRDSKLTRLLQ CCCCCCHHHHHHHHH	22.14	27732954
327	Ubiquitination	HVPYRDSKLTRLLQD CCCCCHHHHHHHHHH	59.16	-
329	Phosphorylation	PYRDSKLTRLLQDSL CCCHHHHHHHHHHHC	24.02	20068231
445	Phosphorylation	RIKAMQETVDALRSR HHHHHHHHHHHHHHH	13.54	23532336
454	Phosphorylation	DALRSRITQLVSDQA HHHHHHHHHHHHHHH	18.10	25278378
458	Phosphorylation	SRITQLVSDQANHVL HHHHHHHHHHHHHHH	32.37	25278378
481	Phosphorylation	EISNMIHSYIKEIED HHHHHHHHHHHHHHH	20.03	24719451
516	Phosphorylation	RATARAPYFSGSSTF HHHHCCCCCCCCCCC	14.91	29396449
518	Phosphorylation	TARAPYFSGSSTFSP HHCCCCCCCCCCCCC	31.74	25159151
520	Phosphorylation	RAPYFSGSSTFSPTI CCCCCCCCCCCCCEE	25.63	25159151
521	Phosphorylation	APYFSGSSTFSPTIL CCCCCCCCCCCCEEC	36.68	25159151
522	Phosphorylation	PYFSGSSTFSPTILS CCCCCCCCCCCEECC	29.81	25159151
524	Phosphorylation	FSGSSTFSPTILSSD CCCCCCCCCEECCCC	22.63	28355574
524 (in isoform 2)	Phosphorylation	-	22.63	-
526	Phosphorylation	GSSTFSPTILSSDKE CCCCCCCEECCCCHH	33.09	28387310
529	Phosphorylation	TFSPTILSSDKETIE CCCCEECCCCHHHHH	32.42	29396449
530	Phosphorylation	FSPTILSSDKETIEI CCCEECCCCHHHHHH	49.62	25159151
534	Phosphorylation	ILSSDKETIEIIDLA ECCCCHHHHHHHHHH	29.65	27732954
542	Ubiquitination	IEIIDLAKKDLEKLK HHHHHHHHHHHHHHH	54.86	29967540
566 (in isoform 2)	Phosphorylation	-	59.67	29116813
566 (in isoform 5)	Phosphorylation	-	59.67	29116813
566 (in isoform 6)	Phosphorylation	-	59.67	29116813
568 (in isoform 2)	Phosphorylation	-	63.11	25849741
568 (in isoform 5)	Phosphorylation	-	63.11	25849741
568 (in isoform 6)	Phosphorylation	-	63.11	25849741
571	Phosphorylation	ESNREERSVAGKEDN HCCHHHHHHCCCCCC	21.43	30576142
579	Phosphorylation	VAGKEDNTDTDQEKK HCCCCCCCCCHHHHH	53.23	30576142
581	Phosphorylation	GKEDNTDTDQEKKEE CCCCCCCCHHHHHHH	37.23	25159151
654 (in isoform 2)	Phosphorylation	-	5.37	-
660 (in isoform 2)	Phosphorylation	-	5.74	-
667	Phosphorylation	LIDELENSQKRLQTL HHHHHHHHHHHHHHH	27.92	20068231
673	Phosphorylation	NSQKRLQTLKKQYEE HHHHHHHHHHHHHHH	45.17	21406692
673 (in isoform 4)	Phosphorylation	-	45.17	21406692
678	Phosphorylation	LQTLKKQYEEKLMML HHHHHHHHHHHHHHH	34.63	20068231
705	Phosphorylation	QVLQNLGSVESYSEE HHHHHHCCCCCCCHH	26.36	29214152
708	Phosphorylation	QNLGSVESYSEEKAK HHHCCCCCCCHHHHH	31.63	28555341
710	Phosphorylation	LGSVESYSEEKAKKV HCCCCCCCHHHHHHH	48.86	25627689
711	Ubiquitination	GSVESYSEEKAKKVR CCCCCCCHHHHHHHH	56.11	33845483
724	Ubiquitination	VRSEYEKKLQAMNKE HHHHHHHHHHHHHHH	33.61	33845483
819	Phosphorylation	LEAQKRNQEVVLRRK HHHHHCCHHHHHHHH	49.22	32142685
827	Phosphorylation	EVVLRRKTEEVTALR HHHHHHHHHHHHHHH	35.25	28555341
829	Phosphorylation	VLRRKTEEVTALRRQ HHHHHHHHHHHHHHH	50.85	32142685
840 (in isoform 2)	Phosphorylation	-	5.92	-
841	Phosphorylation	RRQVRPMSDKVAGKV HHHHCCCCHHHCHHH	36.64	18669648
841 (in isoform 2)	Phosphorylation	-	36.64	-
842	Phosphorylation	RQVRPMSDKVAGKVT HHHCCCCHHHCHHHH	43.10	32142685
842 (in isoform 2)	Phosphorylation	-	43.10	-
849	Phosphorylation	DKVAGKVTRKLSSSD HHHCHHHHHHCCCCC	26.10	24719451
849 (in isoform 4)	Phosphorylation	-	26.10	21406692
852	Phosphorylation	AGKVTRKLSSSDAPA CHHHHHHCCCCCCCC	5.60	32142685
852 (in isoform 2)	Phosphorylation	-	5.60	-
853	Phosphorylation	GKVTRKLSSSDAPAQ HHHHHHCCCCCCCCC	30.72	22167270
853 (in isoform 4)	Phosphorylation	-	30.72	21406692
854	Phosphorylation	KVTRKLSSSDAPAQD HHHHHCCCCCCCCCC	42.55	22167270
855	Phosphorylation	VTRKLSSSDAPAQDT HHHHCCCCCCCCCCC	34.12	22167270
855 (in isoform 4)	Phosphorylation	-	34.12	21406692
862	Phosphorylation	SDAPAQDTGSSAAAV CCCCCCCCCCCCCEE	27.21	30278072
862 (in isoform 4)	Phosphorylation	-	27.21	21406692
864	Phosphorylation	APAQDTGSSAAAVET CCCCCCCCCCCEECC	20.92	30278072
865	Phosphorylation	PAQDTGSSAAAVETD CCCCCCCCCCEECCC	24.23	23927012
871	Phosphorylation	SSAAAVETDASRTGA CCCCEECCCHHCCCC	30.21	23927012
874	Phosphorylation	AAVETDASRTGAQQK CEECCCHHCCCCCHH	32.93	23403867
876	Phosphorylation	VETDASRTGAQQKMR ECCCHHCCCCCHHCC	34.08	21406692
881	Ubiquitination	SRTGAQQKMRIPVAR HCCCCCHHCCCCEEE	20.33	32142685
894	Phosphorylation	ARVQALPTPATNGNR EEEEECCCCCCCCCC	26.80	28555341
894	Ubiquitination	ARVQALPTPATNGNR EEEEECCCCCCCCCC	26.80	27667366
897	Phosphorylation	QALPTPATNGNRKKY EECCCCCCCCCCHHH	44.88	28555341
904	Ubiquitination	TNGNRKKYQRKGLTG CCCCCHHHCCCCCCC	19.31	32142685
917	Ubiquitination	TGRVFISKTARMKWQ CCCEEEEHHHHHHHH	41.19	32142685
1015	Ubiquitination	ANIMQMEEAKEEGET HHHHHHHHHHHHCCC	60.75	23503661
1022	Ubiquitination	EAKEEGETLDVTAVI HHHHHCCCCCHHHHH	38.83	23000965
1027	Ubiquitination	GETLDVTAVINACTL CCCCCHHHHHHHHCH	10.47	23000965
1028	Ubiquitination	ETLDVTAVINACTLT CCCCHHHHHHHHCHH	2.24	23503661
1035	Ubiquitination	VINACTLTEARYLLD HHHHHCHHHHHHHHH	14.94	23000965
1038	Ubiquitination	ACTLTEARYLLDHFL HHCHHHHHHHHHHHH	19.19	23503661
1038 (in isoform 2)	Ubiquitination	-	19.19	-
1040	Ubiquitination	TLTEARYLLDHFLSM CHHHHHHHHHHHHHC	3.64	23000965
1045	Ubiquitination	RYLLDHFLSMGINKG HHHHHHHHHCCHHHH	2.86	23000965
1045 (in isoform 2)	Ubiquitination	-	2.86	-
1046	Phosphorylation	YLLDHFLSMGINKGL HHHHHHHHCCHHHHH	17.64	-
1050	Ubiquitination	HFLSMGINKGLQAAQ HHHHCCHHHHHHHHH	26.98	23000965
1051	Ubiquitination	FLSMGINKGLQAAQK HHHCCHHHHHHHHHH	60.11	23503661
1058	Ubiquitination	KGLQAAQKEAQIKVL HHHHHHHHHHHHHHH	50.74	23000965
1063	Acetylation	AQKEAQIKVLEGRLK HHHHHHHHHHHHHCC	28.78	23236377
1063	Ubiquitination	AQKEAQIKVLEGRLK HHHHHHHHHHHHHCC	28.78	23000965
1099 (in isoform 5)	Phosphorylation	-	19.81	22496350
1100 (in isoform 5)	Phosphorylation	-	6.17	27067055
1108 (in isoform 5)	Phosphorylation	-	3.22	25921289
1111 (in isoform 5)	Phosphorylation	-	6.65	25921289
1119	Phosphorylation	PLENVEDSTDEDAPL CCCCCCCCCCCCCCC	25.01	24275569
1120	Phosphorylation	LENVEDSTDEDAPLN CCCCCCCCCCCCCCC	56.59	22496350
1128	Phosphorylation	DEDAPLNSPGSEGST CCCCCCCCCCCCCCC	38.02	25921289
1148	Acetylation	MKLCGEVKPKNKARR HHHHCCCCCCCHHCC	46.07	27452117
1157	Phosphorylation	KNKARRRTTTQMELL CCHHCCCCCCCEEEE	32.17	20736484
1158	Phosphorylation	NKARRRTTTQMELLY CHHCCCCCCCEEEEE	17.14	-
1176	Phosphorylation	SELASDTSTGDASLP HHHCCCCCCCCCCCC	35.07	32142685
1187	Phosphorylation	ASLPGPLTPVAEGQE CCCCCCCCCCCCCCE	20.89	28348404
1192	Phosphorylation	PLTPVAEGQEIGMNT CCCCCCCCCEECCCC	22.23	32142685
1199	Phosphorylation	GQEIGMNTETSGTSA CCEECCCCCCCCCCC	31.57	32142685
1199 (in isoform 2)	Phosphorylation	-	31.57	-
1203	Phosphorylation	GMNTETSGTSAREKE CCCCCCCCCCCCHHH	30.98	32142685
1210 (in isoform 2)	Phosphorylation	-	50.13	-
1212	Phosphorylation	SAREKELSPPPGLPS CCCHHHCCCCCCCCH	36.13	29255136
1212 (in isoform 2)	Phosphorylation	-	36.13	-
1212 (in isoform 4)	Phosphorylation	-	36.13	21406692
1216 (in isoform 2)	Phosphorylation	-	56.87	-
1219	Phosphorylation	SPPPGLPSKIGSISR CCCCCCCHHHHCCCC	41.78	23403867
1223	Phosphorylation	GLPSKIGSISRQSSL CCCHHHHCCCCCCCC	22.36	25159151
1225	Phosphorylation	PSKIGSISRQSSLSE CHHHHCCCCCCCCCC	26.43	23927012
1225 (in isoform 4)	Phosphorylation	-	26.43	21406692
1226	Phosphorylation	SKIGSISRQSSLSEK HHHHCCCCCCCCCCC	38.44	32142685
1226 (in isoform 2)	Phosphorylation	-	38.44	-
1228	Phosphorylation	IGSISRQSSLSEKKI HHCCCCCCCCCCCCC	31.94	23927012
1229	Phosphorylation	GSISRQSSLSEKKIP HCCCCCCCCCCCCCC	27.81	23927012
1229 (in isoform 2)	Phosphorylation	-	27.81	-
1229 (in isoform 4)	Phosphorylation	-	27.81	21406692
1231	Phosphorylation	ISRQSSLSEKKIPEP CCCCCCCCCCCCCCC	49.68	25159151
1231 (in isoform 4)	Phosphorylation	-	49.68	21406692
1235	Phosphorylation	SSLSEKKIPEPSPVT CCCCCCCCCCCCCCH	7.47	33259812
1239	Phosphorylation	EKKIPEPSPVTRRKA CCCCCCCCCCHHHHH	30.27	19664994
1239 (in isoform 4)	Phosphorylation	-	30.27	21406692
1242	Phosphorylation	IPEPSPVTRRKAYEK CCCCCCCHHHHHHHH	28.30	29255136
1249	Acetylation	TRRKAYEKAEKSKAK HHHHHHHHHHHHHHH	49.52	19822249
1251	Phosphorylation	RKAYEKAEKSKAKEQ HHHHHHHHHHHHHHH	69.77	33259812
1258	Phosphorylation	EKSKAKEQKHSDSGT HHHHHHHHHCCCCCC	48.32	33259812
1261	Phosphorylation	KAKEQKHSDSGTSEA HHHHHHCCCCCCCCC	40.27	23898821
1261 (in isoform 3)	Phosphorylation	-	40.27	30177828
1263	Phosphorylation	KEQKHSDSGTSEASL HHHHCCCCCCCCCCC	47.16	28348404
1264 (in isoform 3)	Phosphorylation	-	37.95	30177828
1265	Phosphorylation	QKHSDSGTSEASLSP HHCCCCCCCCCCCCC	27.61	21712546
1266	Phosphorylation	KHSDSGTSEASLSPP HCCCCCCCCCCCCCC	34.39	30177828
1266 (in isoform 3)	Phosphorylation	-	34.39	30177828
1267 (in isoform 3)	Phosphorylation	-	41.96	30177828
1269	Phosphorylation	DSGTSEASLSPPSSP CCCCCCCCCCCCCCC	25.90	23898821
1269 (in isoform 3)	Phosphorylation	-	25.90	30177828
1271	Phosphorylation	GTSEASLSPPSSPPS CCCCCCCCCCCCCCC	32.06	30278072
1271 (in isoform 4)	Phosphorylation	-	32.06	21406692
1274	Phosphorylation	EASLSPPSSPPSRPR CCCCCCCCCCCCCCC	59.88	30278072
1275	Phosphorylation	ASLSPPSSPPSRPRN CCCCCCCCCCCCCCC	46.75	30278072
1275 (in isoform 4)	Phosphorylation	-	46.75	21406692
1278	Phosphorylation	SPPSSPPSRPRNELN CCCCCCCCCCCCCCC	59.30	30177828
1291	Phosphorylation	LNVFNRLTVSQGNTS CCCCCCEEECCCCCC	18.18	23663014
1291 (in isoform 4)	Phosphorylation	-	18.18	27732954
1293	Phosphorylation	VFNRLTVSQGNTSVQ CCCCEEECCCCCCCC	27.43	23663014
1293 (in isoform 4)	Phosphorylation	-	27.43	27732954
1297	Phosphorylation	LTVSQGNTSVQQDKS EEECCCCCCCCCCCC	36.78	23663014
1297 (in isoform 4)	Phosphorylation	-	36.78	27732954
1298	Phosphorylation	TVSQGNTSVQQDKSD EECCCCCCCCCCCCC	23.17	23663014
1298 (in isoform 4)	Phosphorylation	-	23.17	27732954
1304	Phosphorylation	TSVQQDKSDESDSSL CCCCCCCCCCCCCCH	55.70	30278072
1304 (in isoform 4)	Phosphorylation	-	55.70	27732954
1307	Phosphorylation	QQDKSDESDSSLSEV CCCCCCCCCCCHHHH	48.02	23663014
1307 (in isoform 4)	Phosphorylation	-	48.02	27732954
1309	Phosphorylation	DKSDESDSSLSEVHR CCCCCCCCCHHHHHH	42.32	23663014
1309 (in isoform 4)	Phosphorylation	-	42.32	27732954
1310	Phosphorylation	KSDESDSSLSEVHRS CCCCCCCCHHHHHHH	40.69	23663014
1310 (in isoform 4)	Phosphorylation	-	40.69	27732954
1312	Phosphorylation	DESDSSLSEVHRSSR CCCCCCHHHHHHHHC	39.25	23663014
1312 (in isoform 4)	Phosphorylation	-	39.25	27732954
1316 (in isoform 4)	Phosphorylation	-	41.31	27732954
1317	Phosphorylation	SLSEVHRSSRRGIIN CHHHHHHHHCCCCCC	17.20	27251275
1318	Phosphorylation	LSEVHRSSRRGIINP HHHHHHHHCCCCCCC	26.42	24719451
1649 (in isoform 2)	Phosphorylation	-	28.56	-
1651 (in isoform 2)	Phosphorylation	-	4.25	-
1660 (in isoform 2)	Phosphorylation	-	40.06	-
1662	Phosphorylation	NLQDGQISDTGDLGE CCCCCCCCCCCCCCH	22.64	30266825
1664	Phosphorylation	QDGQISDTGDLGEDI CCCCCCCCCCCCHHH	26.29	30266825
1673	Phosphorylation	DLGEDIASN------ CCCHHHHCC------	43.32	30266825

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KI21A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KI21A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KI21A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TCPZ_HUMAN	CCT6A	physical	26496610
M3K4_HUMAN	MAP3K4	physical	26496610
NVL_HUMAN	NVL	physical	26496610
PFD1_HUMAN	PFDN1	physical	26496610
PFD2_HUMAN	PFDN2	physical	26496610
RAD51_HUMAN	RAD51	physical	26496610
RBM4_HUMAN	RBM4	physical	26496610
TBX3_HUMAN	TBX3	physical	26496610
TCPA_HUMAN	TCP1	physical	26496610
TCPG_HUMAN	CCT3	physical	26496610
NCOA4_HUMAN	NCOA4	physical	26496610
UBL4A_HUMAN	UBL4A	physical	26496610
LIPB1_HUMAN	PPFIBP1	physical	26496610
NOLC1_HUMAN	NOLC1	physical	26496610
TCPH_HUMAN	CCT7	physical	26496610
TCPD_HUMAN	CCT4	physical	26496610
TCPB_HUMAN	CCT2	physical	26496610
TACC2_HUMAN	TACC2	physical	26496610
TCPQ_HUMAN	CCT8	physical	26496610
RFIP2_HUMAN	RAB11FIP2	physical	26496610
TCPE_HUMAN	CCT5	physical	26496610
ENDD1_HUMAN	ENDOD1	physical	26496610
KANK1_HUMAN	KANK1	physical	26496610
KANK2_HUMAN	KANK2	physical	26496610
NOL8_HUMAN	NOL8	physical	26496610
PLXA3_HUMAN	PLXNA3	physical	26496610
PHRF1_HUMAN	PHRF1	physical	26496610
RN123_HUMAN	RNF123	physical	26496610
ZN106_HUMAN	ZNF106	physical	26496610
ZN668_HUMAN	ZNF668	physical	26496610
FIP1_HUMAN	FIP1L1	physical	26496610
C99L2_HUMAN	CD99L2	physical	26496610
MSI2H_HUMAN	MSI2	physical	26496610
DGKH_HUMAN	DGKH	physical	26496610
CF136_HUMAN	C6orf136	physical	26496610
TTC9C_HUMAN	TTC9C	physical	26496610

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 135700: Fibrosis of extraocular muscles, congenital, 1 (CFEOM1)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1212; SER-1223;SER-1225; SER-1229 AND SER-1239, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1212; SER-1239; SER-1662AND SER-1673, AND MASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1271 AND SER-1274, ANDMASS SPECTROMETRY.
PubMed: 18220336

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1212 AND SER-1239, ANDMASS SPECTROMETRY.
PubMed: 18187866