C99L2_HUMAN - dbPTM
C99L2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID C99L2_HUMAN
UniProt AC Q8TCZ2
Protein Name CD99 antigen-like protein 2
Gene Name CD99L2
Organism Homo sapiens (Human).
Sequence Length 262
Subcellular Localization Cell membrane
Single-pass type I membrane protein
Extracellular side. Cell junction.
Protein Description Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity)..
Protein Sequence MVAWRSAFLVCLAFSLATLVQRGSGDFDDFNLEDAVKETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWNHVTTTTKRPVTTRAPANTLGNDFDLADALDDRNDRDDGRRKPIAGGGGFSDKDLEDIVGGGEYKPDKGKGDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEPQVKYSTLHTQSAEPPPPPEPARI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
15PhosphorylationFLVCLAFSLATLVQR
HHHHHHHHHHHHHHC		16.1025348772
18PhosphorylationCLAFSLATLVQRGSG
HHHHHHHHHHHCCCC		32.5225348772
40O-linked_GlycosylationEDAVKETSSVKQPWD
HHHHHHCCCCCCCCC		33.9455821391
41O-linked_GlycosylationDAVKETSSVKQPWDH
HHHHHCCCCCCCCCC		40.5355821397
49O-linked_GlycosylationVKQPWDHTTTTTTNR
CCCCCCCCCCCCCCC		24.30OGP
50PhosphorylationKQPWDHTTTTTTNRP
CCCCCCCCCCCCCCC		20.8020068231
50 (in isoform 2)Phosphorylation-20.8020068231
50O-linked_GlycosylationKQPWDHTTTTTTNRP
CCCCCCCCCCCCCCC		20.80OGP
51O-linked_GlycosylationQPWDHTTTTTTNRPG
CCCCCCCCCCCCCCC		24.25OGP
52O-linked_GlycosylationPWDHTTTTTTNRPGT
CCCCCCCCCCCCCCC		29.54OGP
53O-linked_GlycosylationWDHTTTTTTNRPGTT
CCCCCCCCCCCCCCC		21.71OGP
54O-linked_GlycosylationDHTTTTTTNRPGTTR
CCCCCCCCCCCCCCC		27.43OGP
59O-linked_GlycosylationTTTNRPGTTRAPAKP
CCCCCCCCCCCCCCC		18.78OGP
60O-linked_GlycosylationTTNRPGTTRAPAKPP
CCCCCCCCCCCCCCC		30.65OGP
69O-linked_GlycosylationAPAKPPGSGLDLADA
CCCCCCCCCCCHHHH		41.79OGP
99O-linked_GlycosylationRERWNHVTTTTKRPV
HHHCCCCCCCCCCCC		15.7555821329
99PhosphorylationRERWNHVTTTTKRPV
HHHCCCCCCCCCCCC		15.7520068231
100O-linked_GlycosylationERWNHVTTTTKRPVT
HHCCCCCCCCCCCCC		31.2355821333
100PhosphorylationERWNHVTTTTKRPVT
HHCCCCCCCCCCCCC		31.2320068231
101O-linked_GlycosylationRWNHVTTTTKRPVTT
HCCCCCCCCCCCCCC		22.4355821337
101PhosphorylationRWNHVTTTTKRPVTT
HCCCCCCCCCCCCCC		22.4320068231
102O-linked_GlycosylationWNHVTTTTKRPVTTR
CCCCCCCCCCCCCCC		23.9855821341
102PhosphorylationWNHVTTTTKRPVTTR
CCCCCCCCCCCCCCC		23.9820068231
107O-linked_GlycosylationTTTKRPVTTRAPANT
CCCCCCCCCCCCCCC		17.1655821345
107PhosphorylationTTTKRPVTTRAPANT
CCCCCCCCCCCCCCC		17.1624702127
108PhosphorylationTTKRPVTTRAPANTL
CCCCCCCCCCCCCCC		25.6824702127
108O-linked_GlycosylationTTKRPVTTRAPANTL
CCCCCCCCCCCCCCC		25.6855821349
114O-linked_GlycosylationTTRAPANTLGNDFDL
CCCCCCCCCCCCCCH		37.84OGP
146PhosphorylationIAGGGGFSDKDLEDI
CCCCCCCCHHCHHHH		47.2029507054
146O-linked_GlycosylationIAGGGGFSDKDLEDI
CCCCCCCCHHCHHHH		47.20OGP
163UbiquitinationGGEYKPDKGKGDGRY
CCCCCCCCCCCCCCC		71.67-
165AcetylationEYKPDKGKGDGRYGS
CCCCCCCCCCCCCCC		60.627662541
214S-palmitoylationSYQQKKFCFSIQQGL
HHCHHHHHHHHCCCC		3.4329575903
225PhosphorylationQQGLNADYVKGENLE
CCCCCCCCCCCCCCE		11.1425884760
227UbiquitinationGLNADYVKGENLEAV
CCCCCCCCCCCCEEE		55.04-
242UbiquitinationVCEEPQVKYSTLHTQ
EECCCCCCEEEECCC		28.39-
243PhosphorylationCEEPQVKYSTLHTQS
ECCCCCCEEEECCCC		14.1825159151
244PhosphorylationEEPQVKYSTLHTQSA
CCCCCCEEEECCCCC		20.8325159151
245PhosphorylationEPQVKYSTLHTQSAE
CCCCCEEEECCCCCC		21.3325159151
248PhosphorylationVKYSTLHTQSAEPPP
CCEEEECCCCCCCCC		27.6023401153
250O-linked_GlycosylationYSTLHTQSAEPPPPP
EEEECCCCCCCCCCC		35.44OGP
250PhosphorylationYSTLHTQSAEPPPPP
EEEECCCCCCCCCCC		35.4425159151
254 (in isoform 5)Phosphorylation-45.6027251275
255 (in isoform 5)Phosphorylation-68.7224719451
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of C99L2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of C99L2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of C99L2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of C99L2_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of C99L2_HUMAN

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Related Literatures of Post-Translational Modification

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