SPIN4_HUMAN - dbPTM
SPIN4_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SPIN4_HUMAN
UniProt AC Q56A73
Protein Name Spindlin-4
Gene Name SPIN4
Organism Homo sapiens (Human).
Sequence Length 249
Subcellular Localization
Protein Description Exhibits H3K4me3-binding activity..
Protein Sequence MSPPTVPPMGVDGVSAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRIDSRLADSLIGKAVEHVFEGEHGTKDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQEPGEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVKTP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSPPTVPPM
------CCCCCCCCC		39.3223401153
5Phosphorylation---MSPPTVPPMGVD
---CCCCCCCCCCCC		49.3721406692
15PhosphorylationPMGVDGVSAYLMKKR
CCCCCHHHHHHHHHC		19.4121406692
17PhosphorylationGVDGVSAYLMKKRHT
CCCHHHHHHHHHCCC		10.3823401153
50UbiquitinationCRIQHGWKEGNEPVE
EEECCCCCCCCCCHH		61.4121890473
50UbiquitinationCRIQHGWKEGNEPVE
EEECCCCCCCCCCHH		61.4121890473
81UbiquitinationYIIKYDGKDSVYGLE
EEEEECCCCCEEEEE		43.8829967540
83PhosphorylationIKYDGKDSVYGLELH
EEECCCCCEEEEEEC		22.2630243723
107PhosphorylationILPERVPTPRIDSRL
ECCCCCCCCCCCHHH		23.4922798277
121UbiquitinationLADSLIGKAVEHVFE
HHHHHHHHHHHHHHC		42.1229967540
134UbiquitinationFEGEHGTKDEWKGMV
HCCCCCCCCEECCEE		59.2429967540
171PhosphorylationMYTLLDDYKDGDLRI
EEEECCCCCCCCEEE		15.6222817900
172UbiquitinationYTLLDDYKDGDLRII
EEECCCCCCCCEEEC		63.3321906983
203UbiquitinationVVDSLVGKQVEHAKD
CHHHHCCCCEEECCC		43.6329967540
241PhosphorylationFDDDIHIYVYGLVKT
ECCCEEEEEEEEEEC		3.5725072903
243PhosphorylationDDIHIYVYGLVKTP-
CCEEEEEEEEEECC-		6.4325072903
248PhosphorylationYVYGLVKTP------
EEEEEEECC------		27.1025072903
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SPIN4_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SPIN4_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SPIN4_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of SPIN4_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SPIN4_HUMAN

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Related Literatures of Post-Translational Modification

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