dbPTM

WDFY3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	WDFY3_HUMAN
UniProt AC	Q8IZQ1
Protein Name	WD repeat and FYVE domain-containing protein 3
Gene Name	WDFY3
Organism	Homo sapiens (Human).
Sequence Length	3526
Subcellular Localization	Nucleus membrane . Cytoplasm, cytosol . Nucleus, PML body . Membrane Peripheral membrane protein Cytoplasmic side . Perikaryon . Cell projection, axon . Relocalization from the nucleus to the cytosol is stimulated by cellular stress, such as starv
Protein Description	Required for selective macroautophagy (aggrephagy). Acts as an adapter protein by linking specific proteins destined for degradation to the core autophagic machinery members, such as the ATG5-ATG12-ATG16L E3-like ligase, SQSTM1 and LC3. [PubMed: 20417604 Along with p62/SQSTM1, involved in the formation and autophagic degradation of cytoplasmic ubiquitin-containing inclusions (p62 bodies, ALIS/aggresome-like induced structures Along with SQSTM1, required to recruit ubiquitinated proteins to PML bodies in the nucleus]
Protein Sequence	MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	RPRQEECSPQDNALG CCCCHHCCHHCCHHH	28.95	21712546
33	Phosphorylation	MHLRRLFTELCHPPR HHHHHHHHHHHCCCC	32.41	29449344
43	Phosphorylation	CHPPRHMTQKEQEEK HCCCCCCCHHHHHHH	30.29	29449344
45	Ubiquitination	PPRHMTQKEQEEKLY CCCCCCHHHHHHHHH	52.80	21906983
45 (in isoform 1)	Ubiquitination	-	52.80	21890473
45 (in isoform 2)	Ubiquitination	-	52.80	21890473
52	Phosphorylation	KEQEEKLYMMLPVFN HHHHHHHHHHHHHHH	7.49	27642862
69	Phosphorylation	FGNAPPNTMTEKFSD HCCCCCCCCHHHHHH	31.10	25332170
71	Phosphorylation	NAPPNTMTEKFSDLL CCCCCCCHHHHHHHH	33.70	25332170
81	Phosphorylation	FSDLLQFTTQVSRLM HHHHHHHHHHHHHHH	11.89	-
82	Phosphorylation	SDLLQFTTQVSRLMV HHHHHHHHHHHHHHH	28.41	-
234	Phosphorylation	YNLPWRKSAGEVLMT CCCCCCCCHHHHHHH	32.69	-
241	Phosphorylation	SAGEVLMTISRHGLS CHHHHHHHHCCCCCE	16.19	-
262	Phosphorylation	IHEKECLSTCVQNMQ HCHHHHHHHHHHHHH	31.27	22817900
271	Phosphorylation	CVQNMQQSDDLSPLE HHHHHHCCCCCCHHH	19.05	22817900
465	Phosphorylation	IPCKELISVSILLKS CCHHHHEEHHEEECC	23.57	22817900
467	Phosphorylation	CKELISVSILLKSSS HHHHEEHHEEECCCC	10.75	22817900
474	Phosphorylation	SILLKSSSSYHCSII HEEECCCCCCHHHHH	41.84	22817900
521	Ubiquitination	HKYAALLKDPTQALN HHHHHHHCCHHHHHH	63.61	21906983
521 (in isoform 1)	Ubiquitination	-	63.61	21890473
521 (in isoform 2)	Ubiquitination	-	63.61	21890473
524	Phosphorylation	AALLKDPTQALNEQG HHHHCCHHHHHHHHC	36.29	-
633	Phosphorylation	DILRALLSVLRESHR HHHHHHHHHHHHHHH	21.69	24719451
653	Phosphorylation	RKVGGFVYITSLLVA HHHCCHHHHHHHHHH	9.02	17053785
726	Phosphorylation	VRFLGCFSDLRKISA HHHHCCCCCCCHHHC	39.55	24719451
779	Phosphorylation	LYKVATDSFDSRAEQ HHHHHHCCCCCCHHC	26.97	18452278
793	Phosphorylation	QIPPCLTSESSLPSP CCCCCCCCCCCCCCC	23.64	27732954
795	Phosphorylation	PPCLTSESSLPSPWG CCCCCCCCCCCCCCC	36.62	27732954
796	Phosphorylation	PCLTSESSLPSPWGT CCCCCCCCCCCCCCC	40.00	27732954
799	Phosphorylation	TSESSLPSPWGTPAL CCCCCCCCCCCCCCC	38.28	27732954
803	Phosphorylation	SLPSPWGTPALSRKR CCCCCCCCCCCCCCC	11.08	27732954
807	Phosphorylation	PWGTPALSRKRHAYH CCCCCCCCCCCCCCC	37.55	27732954
813	Phosphorylation	LSRKRHAYHSVSTPP CCCCCCCCCCCCCCC	6.62	23403867
815	Phosphorylation	RKRHAYHSVSTPPVY CCCCCCCCCCCCCCC	12.70	29116813
817	Phosphorylation	RHAYHSVSTPPVYPP CCCCCCCCCCCCCCC	37.91	22617229
818	Phosphorylation	HAYHSVSTPPVYPPK CCCCCCCCCCCCCCC	29.47	23898821
822	Phosphorylation	SVSTPPVYPPKNVAD CCCCCCCCCCCCHHH	21.42	23403867
825	Ubiquitination	TPPVYPPKNVADLKL CCCCCCCCCHHHEEE	60.60	-
963	Phosphorylation	DKKLLKQYRVHKPSS CHHHHHHHCCCCCCC	17.02	25884760
969	Phosphorylation	QYRVHKPSSLSYEPE HHCCCCCCCCCCCHH	49.03	23403867
970	Phosphorylation	YRVHKPSSLSYEPEM HCCCCCCCCCCCHHH	29.84	23911959
972	Phosphorylation	VHKPSSLSYEPEMRS CCCCCCCCCCHHHHH	29.42	23403867
973	Phosphorylation	HKPSSLSYEPEMRSS CCCCCCCCCHHHHHH	40.57	23403867
983	Phosphorylation	EMRSSMITSLEGLGT HHHHHHCHHHCCCCC	20.72	28348404
984	Phosphorylation	MRSSMITSLEGLGTD HHHHHCHHHCCCCCC	17.31	24719451
990	Phosphorylation	TSLEGLGTDNVFSLH HHHCCCCCCCCEECC	29.46	30624053
1006	Ubiquitination	DNHYRISKSLVKSAE CCCEEECHHHHHCCC	45.50	-
1011	Phosphorylation	ISKSLVKSAEGSTVP ECHHHHHCCCCCCCC	24.87	22817900
1015	Phosphorylation	LVKSAEGSTVPLTRV HHHCCCCCCCCCCEE	20.10	17081983
1016	Phosphorylation	VKSAEGSTVPLTRVK HHCCCCCCCCCCEEE	36.68	17081983
1020	Phosphorylation	EGSTVPLTRVKCLVS CCCCCCCCEEEEEEE	27.61	17081983
1027	Phosphorylation	TRVKCLVSMTTPHDI CEEEEEEECCCCCCE	9.47	27135362
1029	Phosphorylation	VKCLVSMTTPHDIRL EEEEEECCCCCCEEE	29.66	27135362
1030	Phosphorylation	KCLVSMTTPHDIRLH EEEEECCCCCCEEEC	15.24	27135362
1153	Phosphorylation	KDRSLIVSTKEELLQ CCCCEEECCHHHHHH	27.11	28787133
1154	Phosphorylation	DRSLIVSTKEELLQN CCCEEECCHHHHHHH	31.42	28787133
1353	Ubiquitination	LDSKAIAKQLGISSH CCHHHHHHHHCCCCC	39.69	21890473
1353	Malonylation	LDSKAIAKQLGISSH CCHHHHHHHHCCCCC	39.69	26320211
1353 (in isoform 1)	Ubiquitination	-	39.69	21890473
1353 (in isoform 2)	Ubiquitination	-	39.69	21890473
1358	Phosphorylation	IAKQLGISSHENATP HHHHHCCCCCCCCCC	24.68	26699800
1359	Phosphorylation	AKQLGISSHENATPV HHHHCCCCCCCCCCC	32.66	26699800
1364	Phosphorylation	ISSHENATPVKLIHN CCCCCCCCCCEEEEC	39.95	26699800
1643	Ubiquitination	RLLDILLKLIYTSKE HHHHHHHHHHHCCCC	29.41	-
1646	Phosphorylation	DILLKLIYTSKEKTS HHHHHHHHCCCCCCC	18.52	28331001
1647	Phosphorylation	ILLKLIYTSKEKTSI HHHHHHHCCCCCCCC	26.74	25278378
1648	Phosphorylation	LLKLIYTSKEKTSIN HHHHHHCCCCCCCCC	23.11	25278378
1696	Phosphorylation	RILVVLLSNQSILIK HHHHHHHCCCEEEEE	28.76	22817900
1699	Phosphorylation	VVLLSNQSILIKFKE HHHHCCCEEEEEECC	24.50	22817900
1709	Phosphorylation	IKFKEGLSGGGWLEQ EEECCCCCCCCHHHH	46.37	-
1852	Phosphorylation	GMLRSMLTSPWQSEE HHHHHHHCCCCCCCC	24.89	30576142
1857	Phosphorylation	MLTSPWQSEEEGSWL HHCCCCCCCCCCCCH	43.01	30576142
1862	Phosphorylation	WQSEEEGSWLREYPV CCCCCCCCCHHHCCH	26.64	30576142
1923	Phosphorylation	DLDDEVGSPAEEFKA CCCCCCCCHHHHHHH	26.55	27732954
1940	Phosphorylation	ADTGMNRSQSEYCNV HHCCCCCCHHHCCCC	32.81	25159151
1942	Phosphorylation	TGMNRSQSEYCNVGT CCCCCCHHHCCCCCC	31.60	28796482
1944	Phosphorylation	MNRSQSEYCNVGTKT CCCCHHHCCCCCCCC	8.45	28796482
1949	Phosphorylation	SEYCNVGTKTYLTNH HHCCCCCCCCCCCCC	18.87	25072903
1950	Ubiquitination	EYCNVGTKTYLTNHP HCCCCCCCCCCCCCC	29.28	-
2083	Phosphorylation	IAQSKRRSQGLSLDA HHHHHHHCCCCCHHH	32.41	-
2104	Phosphorylation	RTILYQFSRAHKTVP HHHHHHHHCCCCCCH	17.03	24719451
2177	Phosphorylation	TWHIMIPSDIEPDGS EEEEEECCCCCCCCC	40.05	-
2184	Phosphorylation	SDIEPDGSYSQDISE CCCCCCCCCCCCCHH	29.05	-
2185	Phosphorylation	DIEPDGSYSQDISEG CCCCCCCCCCCCHHH	18.84	-
2190	Phosphorylation	GSYSQDISEGRQLLI CCCCCCCHHHHHHHH	42.14	-
2222	Phosphorylation	LEELFKVTLPVNERG HHHHHCCCCCCCCCC	26.40	26270265
2272	Ubiquitination	LAPTTQSKLSRVSSG CCCCCHHHHHHHHCC	40.44	-
2274	Phosphorylation	PTTQSKLSRVSSGFG CCCHHHHHHHHCCCC	34.08	29514088
2277	Phosphorylation	QSKLSRVSSGFGLSK HHHHHHHHCCCCHHH	24.51	30266825
2278	Phosphorylation	SKLSRVSSGFGLSKL HHHHHHHCCCCHHHH	34.97	30266825
2283	Phosphorylation	VSSGFGLSKLTGSRR HHCCCCHHHHCCCCC	26.46	30266825
2412	Phosphorylation	NVASEIPSKQPETPD CCCCCCCCCCCCCCC	49.97	24719451
2434	Phosphorylation	ARYRRAVSYDSKEYY CHHEEEECCCCHHHH	23.41	28857561
2490	Phosphorylation	VKPPLKRSRSAPDGG CCCCCCCCCCCCCCC	29.06	27251789
2492	Phosphorylation	PPLKRSRSAPDGGDE CCCCCCCCCCCCCCH	45.45	23927012
2573	Phosphorylation	DGFTMTATREIRDIE ECEEEEECEEECCCC	21.48	24719451
2600	Phosphorylation	RGARQGPSQLKRTCS CCCCCCHHHHHHHHE	55.77	24702127
2807	Phosphorylation	LVRMEPFTQIFLRLQ HHCCCCCCHHHHHHC	31.32	24719451
2980	O-linked_Glycosylation	HPPKRVRSRLNGDNA CCCHHHHHHCCCCCC	37.96	29351928
2990	O-linked_Glycosylation	NGDNAGISVLPGSTS CCCCCCEEECCCCCC	19.38	29351928
3305	Phosphorylation	KDTPSQPSSTSHRPR CCCCCCCCCCCCCCC	38.31	25627689
3306	Phosphorylation	DTPSQPSSTSHRPRA CCCCCCCCCCCCCCC	40.38	25627689
3307	Phosphorylation	TPSQPSSTSHRPRAA CCCCCCCCCCCCCCH	32.65	25627689
3308	Phosphorylation	PSQPSSTSHRPRAAS CCCCCCCCCCCCCHH	21.32	25159151
3319	Phosphorylation	RAASCRATAAWCTDS CCHHCCEEEHHHCCC	9.50	24043423
3324	Phosphorylation	RATAAWCTDSGSDDS CEEEHHHCCCCCCCC	23.62	27732954
3326	Phosphorylation	TAAWCTDSGSDDSRR EEHHHCCCCCCCCCH	23.26	22777824
3328	Phosphorylation	AWCTDSGSDDSRRWS HHHCCCCCCCCCHHH	42.04	22777824
3331	Phosphorylation	TDSGSDDSRRWSDQL CCCCCCCCCHHHCCC	28.83	27732954
3335	Phosphorylation	SDDSRRWSDQLSLDE CCCCCHHHCCCCCCC	17.42	25159151
3339	Phosphorylation	RRWSDQLSLDEKDGF CHHHCCCCCCCCCCE	28.30	19664994
3351	Phosphorylation	DGFIFVNYSEGQTRA CCEEEEECCCCCCEE	11.64	27642862
3472	Methylation	VRFSLTERRHHCRNC EEEECCCCCHHHCCH	37.69	54560511
3500	Phosphorylation	EIKRLKISSPVRVCQ HHHHCCCCCCHHHHH	27.31	22617229
3501	Phosphorylation	IKRLKISSPVRVCQN HHHCCCCCCHHHHHC	30.78	25056879
3510	Phosphorylation	VRVCQNCYYNLQHER HHHHHCCHHHCCCCC	11.70	23312004
3519	Phosphorylation	NLQHERGSEDGPRNC HCCCCCCCCCCCCCC	38.44	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of WDFY3_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of WDFY3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of WDFY3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SQSTM_HUMAN	SQSTM1	physical	20168092
MLP3A_HUMAN	MAP1LC3A	physical	20168092
ATG12_HUMAN	ATG12	physical	20417604
A16L1_HUMAN	ATG16L1	physical	20417604
TRAF6_HUMAN	TRAF6	physical	24128730
SQSTM_HUMAN	SQSTM1	physical	24128730
ANM1_HUMAN	PRMT1	physical	23455924
ANM6_HUMAN	PRMT6	physical	23455924
SUV91_HUMAN	SUV39H1	physical	23455924
ZBT44_HUMAN	ZBTB44	physical	25416956
TRI39_HUMAN	TRIM39	physical	25416956
CEP76_HUMAN	CEP76	physical	25416956
GBRAP_HUMAN	GABARAP	physical	24668264
P55G_HUMAN	PIK3R3	physical	25814554
MDFI_HUMAN	MDFI	physical	21516116
TRI39_HUMAN	TRIM39	physical	21516116
FLCN_HUMAN	FLCN	physical	28514442
HERC1_HUMAN	HERC1	physical	28514442
DCAF6_HUMAN	DCAF6	physical	28514442
APAF_HUMAN	APAF1	physical	28514442
MIRO2_HUMAN	RHOT2	physical	28514442
DMWD_HUMAN	DMWD	physical	28514442
DDX11_HUMAN	DDX11	physical	28514442
WDR60_HUMAN	WDR60	physical	28514442
WDR75_HUMAN	WDR75	physical	28514442
ALG13_HUMAN	ALG13	physical	28514442
DPYL4_HUMAN	DPYSL4	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of WDFY3_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-813; SER-815; SER-817;THR-818 AND TYR-822, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1696 AND SER-1699, ANDMASS SPECTROMETRY.	18187866 [Abstract]
"Tyrosine phosphorylated Par3 regulates epithelial tight junctionassembly promoted by EGFR signaling."; Wang Y., Du D., Fang L., Yang G., Zhang C., Zeng R., Ullrich A.,Lottspeich F., Chen Z.; EMBO J. 25:5058-5070(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-653, AND MASSSPECTROMETRY.	17053785 [Abstract]