dbPTM

NT5D4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NT5D4_HUMAN
UniProt AC	Q86YG4
Protein Name	5'-nucleotidase domain-containing protein 4
Gene Name	NT5DC4
Organism	Homo sapiens (Human).
Sequence Length	428
Subcellular Localization
Protein Description
Protein Sequence	MPAWIFVNRSLALGKIRCFGFDMDYTLAAYKSPAYEALTFELLLERLVCIGYPHEILRYTYDPTFPTRRLVFDELYGNLLKVDAHGNVLLGAYGFTFLSEAEIWSFYPSKFIQRDDLQCFYILNMLFNLPETYLYACLVDFFSGCSRYTNCDTGYQHGNLFMSFRSLFQDVTDAMNNIHQSGCLKKTLEDLEKYVKKDPRLPILLGKMKEVGKVFLATNSSYNYTNAIMTYLFSISEAEASGRPWRSYFDLIVVDTQKPHFFAEGLVLRQVNTDSGKLHVGTSTGPHQHCAVYSGGSSDMVCELLGVRGMDILYIGDHIFGDILKSKKRQGWRTCLVVPELSWELDIWAQEKERLEELKRLDTHLADIYQHMDGSSCELQVINFTKREIQMPHESVVEQEQANLDPASCLLSCNQRSLPAKSCLSSAI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Phosphorylation	YPHEILRYTYDPTFP CCHHHHHHCCCCCCC	13.25	-
163	Phosphorylation	QHGNLFMSFRSLFQD CCCCCHHHHHHHHHH	15.35	24719451
218	Phosphorylation	VGKVFLATNSSYNYT CCEEEEEECCCCCCH	37.47	22210691
220	Phosphorylation	KVFLATNSSYNYTNA EEEEEECCCCCCHHH	29.82	22210691
247	Phosphorylation	ASGRPWRSYFDLIVV HCCCCCHHHEEEEEE	26.70	-
248	Phosphorylation	SGRPWRSYFDLIVVD CCCCCHHHEEEEEEE	7.79	-
314	Phosphorylation	VRGMDILYIGDHIFG CCCCEEEEEECHHHH	11.82	-
325	Ubiquitination	HIFGDILKSKKRQGW HHHHHHHHCCCCCCC	61.64	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NT5D4_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NT5D4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NT5D4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NT5D4_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NT5D4_HUMAN

Related Literatures of Post-Translational Modification