RWDD4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RWDD4_HUMAN
• UniProt AC: Q6NW29
• Protein Name: RWD domain-containing protein 4
• Gene Name: RWDD4
• Organism: Homo sapiens (Human).
• Sequence Length: 188
• Protein Sequence: MSANEDQEMELEALRSIYEGDESFRELSPVSFQYRIGENGDPKAFLIEISWTETYPQTPPILSMNAFFNNTISSAVKQSILAKLQEAVEANLGTAMTYTLFEYAKDNKEQFMENHNPINSATSISNIISIETPNTAPSSKKKDKKEQLSKAQKRKLADKTDHKGELPRGWNWVDVVKHLSKTGSKDDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSANEDQEM ------CCCCHHHHH	39.54	30108239
2	Acetylation	------MSANEDQEM ------CCCCHHHHH	39.54	22814378
18	Phosphorylation	LEALRSIYEGDESFR HHHHHHHHHCCCCHH	18.33	28796482
23	Phosphorylation	SIYEGDESFRELSPV HHHHCCCCHHHCCCC	34.05	28450419
28	Phosphorylation	DESFRELSPVSFQYR CCCHHHCCCCEEEEE	20.64	30108239
31	Phosphorylation	FRELSPVSFQYRIGE HHHCCCCEEEEEECC	15.26	20873877
34	Phosphorylation	LSPVSFQYRIGENGD CCCCEEEEEECCCCC	11.37	29514088
64	Ubiquitination	QTPPILSMNAFFNNT CCCCEEEEHHHCCCH	3.63	-
68	Ubiquitination	ILSMNAFFNNTISSA EEEEHHHCCCHHHHH	6.82	-
74	Phosphorylation	FFNNTISSAVKQSIL HCCCHHHHHHHHHHH	32.98	26425664
120	Phosphorylation	ENHNPINSATSISNI HHCCCCCCCCHHHHH	33.37	20068231
122	Phosphorylation	HNPINSATSISNIIS CCCCCCCCHHHHHEE	26.81	20068231
123	Phosphorylation	NPINSATSISNIISI CCCCCCCHHHHHEEE	24.60	20068231
125	Phosphorylation	INSATSISNIISIET CCCCCHHHHHEEEEC	23.03	28348404
129	Phosphorylation	TSISNIISIETPNTA CHHHHHEEEECCCCC	15.58	28348404
132	Phosphorylation	SNIISIETPNTAPSS HHHEEEECCCCCCCC	21.84	20068231
135	Phosphorylation	ISIETPNTAPSSKKK EEEECCCCCCCCCCC	40.94	20068231
138	Phosphorylation	ETPNTAPSSKKKDKK ECCCCCCCCCCCCHH	52.94	20068231
139	Phosphorylation	TPNTAPSSKKKDKKE CCCCCCCCCCCCHHH	47.65	25159151
149	Phosphorylation	KDKKEQLSKAQKRKL CCHHHHHHHHHHHHH	26.16	24702127
159	Ubiquitination	QKRKLADKTDHKGEL HHHHHHHCCCCCCCC	50.69	-
160	Phosphorylation	KRKLADKTDHKGELP HHHHHHCCCCCCCCC	43.83	28555341
163	Acetylation	LADKTDHKGELPRGW HHHCCCCCCCCCCCC	57.82	90573
163	Ubiquitination	LADKTDHKGELPRGW HHHCCCCCCCCCCCC	57.82	-
177	Acetylation	WNWVDVVKHLSKTGS CCHHHHHHHHHHCCC	38.38	90575
180	Phosphorylation	VDVVKHLSKTGSKDD HHHHHHHHHCCCCCC	28.08	24719451
181	Acetylation	DVVKHLSKTGSKDDE HHHHHHHHCCCCCCC	64.36	90577

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RWDD4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RWDD4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RWDD4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZN330_HUMAN	ZNF330	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.