SOX30_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SOX30_HUMAN
• UniProt AC: O94993
• Protein Name: Transcription factor SOX-30
• Gene Name: SOX30
• Organism: Homo sapiens (Human).
• Sequence Length: 753
• Subcellular Localization: Nucleus .
• Protein Description: Transcriptional activator. Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif..
• Protein Sequence: MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVASGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGATSRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRGDEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSAEVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLPTPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTVKQPTPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVYQPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYYEDRYPKHEGIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVPQLDIGTLENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
114	Phosphorylation	LRLLQPPTASDGATS CHHCCCCCCCCCCCC	45.54	22210691
116	Phosphorylation	LLQPPTASDGATSRP HCCCCCCCCCCCCCC	38.77	22210691
120	Phosphorylation	PTASDGATSRPELHP CCCCCCCCCCCCCCC	30.69	25332170
158	Phosphorylation	GPRGAVETGPRASRV CCCCCCCCCCCCCEE	45.98	24425749
163	Phosphorylation	VETGPRASRVVKLEG CCCCCCCCEEEEEEC	27.21	24425749
203	Phosphorylation	MQGGAGKSPAAIREG HCCCCCCCHHHHHCC	20.89	-
292	O-linked_Glycosylation	RLTKVPLTPVPTKMQ ECEECCCCCCCCHHH	19.03	30379171
664	Phosphorylation	PKHEGIFSTLNRDYS CCCCCCHHCCCCCCC	30.02	26270265
665	Phosphorylation	KHEGIFSTLNRDYSF CCCCCHHCCCCCCCC	19.80	26270265
670	Phosphorylation	FSTLNRDYSFRDYSS HHCCCCCCCCCCCCC	13.38	-
676	Phosphorylation	DYSFRDYSSECTHSE CCCCCCCCCCCCCCC	24.77	-
682	Phosphorylation	YSSECTHSENSRSCE CCCCCCCCCCCCCCC	21.96	-
685	Phosphorylation	ECTHSENSRSCENMN CCCCCCCCCCCCCCC	22.86	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SOX30_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SOX30_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SOX30_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BAMBI_HUMAN	BAMBI	physical	16189514
NUDT3_HUMAN	NUDT3	physical	16189514
CF206_HUMAN	C6orf165	physical	25416956
CF206_HUMAN	C6orf165	physical	21516116

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.