RT02_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RT02_HUMAN
• UniProt AC: Q9Y399
• Protein Name: 28S ribosomal protein S2, mitochondrial
• Gene Name: MRPS2
• Organism: Homo sapiens (Human).
• Sequence Length: 296
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MATSSAALPRILGAGARAPSRWLGFLGKATPRPARPSRRTLGSATALMIRESEDSTDFNDKILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPYIFGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFSYLIENMARDCGEYAHTRYFRGGMLTNARLLFGPTVRLPDLIIFLHTLNNIFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQTAITRAKEKRQQVEALYRLQGQKEPGDQGPAHPPGADMSHSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MATSSAALPRI ----CCCCHHHHHHH	14.40	18491316
5	Phosphorylation	---MATSSAALPRIL ---CCCCHHHHHHHH	17.13	18491316
28	Ubiquitination	RWLGFLGKATPRPAR HHHHHCCCCCCCCCC	51.76	-
30	Phosphorylation	LGFLGKATPRPARPS HHHCCCCCCCCCCCC	24.26	-
37	Phosphorylation	TPRPARPSRRTLGSA CCCCCCCCCCCCCCC	28.92	-
40	Phosphorylation	PARPSRRTLGSATAL CCCCCCCCCCCCEEE	34.07	22210691
61	Ubiquitination	DSTDFNDKILNEPLK CCCCCCHHHHCCCCC	50.64	21906983
68	Acetylation	KILNEPLKHSDFFNV HHHCCCCCCCCCCCH	52.34	25953088
68	Ubiquitination	KILNEPLKHSDFFNV HHHCCCCCCCCCCCH	52.34	21906983
76	Ubiquitination	HSDFFNVKELFSVRS CCCCCCHHHHHCHHH	50.21	21963094
84	Ubiquitination	ELFSVRSLFDARVHL HHHCHHHHHHCHHHH	2.93	21906983
91	Ubiquitination	LFDARVHLGHKAGCR HHHCHHHHCCCCCCC	7.61	21906983
99	Ubiquitination	GHKAGCRHRFMEPYI CCCCCCCCCCCCCEE	31.26	21963094
109	Phosphorylation	MEPYIFGSRLDHDII CCCEECCCCCCCCEE	20.94	24719451
146	Phosphorylation	KGIILFISRNRQFSY CCEEEEEECCHHHHH	19.03	20068231
152	Phosphorylation	ISRNRQFSYLIENMA EECCHHHHHHHHHHH	15.64	29083192
153	Phosphorylation	SRNRQFSYLIENMAR ECCHHHHHHHHHHHH	17.00	29083192
255	Phosphorylation	LYCRLFQTAITRAKE HHHHHHHHHHHHHHH	16.82	20068231
258	Phosphorylation	RLFQTAITRAKEKRQ HHHHHHHHHHHHHHH	23.31	20068231
271	Phosphorylation	RQQVEALYRLQGQKE HHHHHHHHHHCCCCC	19.14	-
277	Ubiquitination	LYRLQGQKEPGDQGP HHHHCCCCCCCCCCC	73.10	29967540
300	Ubiquitination	SHSL----------- CCCC-----------		24816145

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RT02_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RT02_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RT02_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
RT16_HUMAN	MRPS16	physical	22939629
RT09_HUMAN	MRPS9	physical	22939629
SSBP_HUMAN	SSBP1	physical	22939629
RT09_HUMAN	MRPS9	physical	26186194
PTCD3_HUMAN	PTCD3	physical	26186194
RT23_HUMAN	MRPS23	physical	26186194
TPD52_HUMAN	TPD52	physical	26186194
RT28_HUMAN	MRPS28	physical	26186194
RT07_HUMAN	MRPS7	physical	26186194
ERAL1_HUMAN	ERAL1	physical	26186194
RT31_HUMAN	MRPS31	physical	26186194
RT11_HUMAN	MRPS11	physical	26186194
RT05_HUMAN	MRPS5	physical	26186194
RT14_HUMAN	MRPS14	physical	26186194
RT33_HUMAN	MRPS33	physical	26186194
TPD54_HUMAN	TPD52L2	physical	26186194
RT18C_HUMAN	MRPS18C	physical	26186194
RT16_HUMAN	MRPS16	physical	26344197
RT18B_HUMAN	MRPS18B	physical	26344197
RT22_HUMAN	MRPS22	physical	26344197
RT23_HUMAN	MRPS23	physical	26344197
RT28_HUMAN	MRPS28	physical	26344197
RT35_HUMAN	MRPS35	physical	26344197
RT09_HUMAN	MRPS9	physical	26344197
PTCD3_HUMAN	PTCD3	physical	26344197
TPD52_HUMAN	TPD52	physical	28514442
RT15_HUMAN	MRPS15	physical	28514442
RT31_HUMAN	MRPS31	physical	28514442
RT27_HUMAN	MRPS27	physical	28514442
RT23_HUMAN	MRPS23	physical	28514442
RT09_HUMAN	MRPS9	physical	28514442
TPD54_HUMAN	TPD52L2	physical	28514442
RT28_HUMAN	MRPS28	physical	28514442
RT05_HUMAN	MRPS5	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.