RT31_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RT31_HUMAN
• UniProt AC: Q92665
• Protein Name: 28S ribosomal protein S31, mitochondrial
• Gene Name: MRPS31
• Organism: Homo sapiens (Human).
• Sequence Length: 395
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MFPRVSTFLPLRPLSRHPLSSGSPETSAAAIMLLTVRHGTVRYRSSALLARTKNNIQRYFGTNSVICSKKDKQSVRTEETSKETSESQDSEKENTKKDLLGIIKGMKVELSTVNVRTTKPPKRRPLKSLEATLGRLRRATEYAPKKRIEPLSPELVAAASAVADSLPFDKQTTKSELLSQLQQHEEESRAQRDAKRPKISFSNIISDMKVARSATARVRSRPELRIQFDEGYDNYPGQEKTDDLKKRKNIFTGKRLNIFDMMAVTKEAPETDTSPSLWDVEFAKQLATVNEQPLQNGFEELIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLEKHLESFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKKDILKESNIQFN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Phosphorylation	TKNNIQRYFGTNSVI HCHHHHHHHCCCCEE	7.03	22817900
84	Phosphorylation	TEETSKETSESQDSE CHHHCCCCCCCCCHH	41.34	-
85	Phosphorylation	EETSKETSESQDSEK HHHCCCCCCCCCHHH	36.02	-
90	Phosphorylation	ETSESQDSEKENTKK CCCCCCCHHHHHCHH	42.82	-
104	Ubiquitination	KDLLGIIKGMKVELS HHHHHHHHCCEEEEE	51.54	-
104	2-Hydroxyisobutyrylation	KDLLGIIKGMKVELS HHHHHHHHCCEEEEE	51.54	-
142	Phosphorylation	RLRRATEYAPKKRIE HHHHHHHCCCCCCCC	24.69	28152594
145	2-Hydroxyisobutyrylation	RATEYAPKKRIEPLS HHHHCCCCCCCCCCC	46.65	-
146	Ubiquitination	ATEYAPKKRIEPLSP HHHCCCCCCCCCCCH	58.51	24816145
146	Acetylation	ATEYAPKKRIEPLSP HHHCCCCCCCCCCCH	58.51	18584577
152	Phosphorylation	KKRIEPLSPELVAAA CCCCCCCCHHHHHHH	27.35	27732954
160	Phosphorylation	PELVAAASAVADSLP HHHHHHHHHHHHCCC	20.67	27732954
170	Ubiquitination	ADSLPFDKQTTKSEL HHCCCCCHHCCHHHH	50.34	22817900
174	Ubiquitination	PFDKQTTKSELLSQL CCCHHCCHHHHHHHH	45.37	22817900
198	Ubiquitination	QRDAKRPKISFSNII HHHHHCCCCCHHHHH	55.82	-
200	Phosphorylation	DAKRPKISFSNIISD HHHCCCCCHHHHHHH	28.84	30576142
202	Phosphorylation	KRPKISFSNIISDMK HCCCCCHHHHHHHHH	21.96	30576142
206	Phosphorylation	ISFSNIISDMKVARS CCHHHHHHHHHHHHH	28.05	30576142
208	Sulfoxidation	FSNIISDMKVARSAT HHHHHHHHHHHHHHC	2.76	21406390
209	Ubiquitination	SNIISDMKVARSATA HHHHHHHHHHHHHCC	37.42	-
215	Phosphorylation	MKVARSATARVRSRP HHHHHHHCCHHHCCC	19.08	-
220	Phosphorylation	SATARVRSRPELRIQ HHCCHHHCCCCEEEE	49.70	-
232	Phosphorylation	RIQFDEGYDNYPGQE EEEECCCCCCCCCCC	10.04	-
235	Phosphorylation	FDEGYDNYPGQEKTD ECCCCCCCCCCCCCC	13.07	32645325
245	Ubiquitination	QEKTDDLKKRKNIFT CCCCCHHHHHHCCCC	58.49	24816145
254	Succinylation	RKNIFTGKRLNIFDM HHCCCCCCCCEEHHH	51.13	27452117
254	Acetylation	RKNIFTGKRLNIFDM HHCCCCCCCCEEHHH	51.13	25953088
274	Phosphorylation	EAPETDTSPSLWDVE CCCCCCCCCCHHCHH	18.46	25022875
343	Malonylation	KHLESFPKQGPIRHF HHHHHCCCCCCHHHH	66.91	26320211
360	Acetylation	LVTCGLSKNPYLSVK HHHCCCCCCCCCCHH	67.97	26051181
367	Ubiquitination	KNPYLSVKQKVEHIE CCCCCCHHHHHHHHH	40.81	-
369	Ubiquitination	PYLSVKQKVEHIEWF CCCCHHHHHHHHHHH	43.82	-
383	2-Hydroxyisobutyrylation	FRNYFNEKKDILKES HHHHHHHHHHHHHHC	57.77	-
388	Ubiquitination	NEKKDILKESNIQFN HHHHHHHHHCCCCCC	60.47	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RT31_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RT31_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RT31_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRPRB_HUMAN	SRPRB	physical	22939629
SARNP_HUMAN	SARNP	physical	22939629
STAT3_HUMAN	STAT3	physical	21988832
RT35_HUMAN	MRPS35	physical	26186194
RT09_HUMAN	MRPS9	physical	26186194
RT26_HUMAN	MRPS26	physical	26186194
PTCD3_HUMAN	PTCD3	physical	26186194
RT15_HUMAN	MRPS15	physical	26186194
RT23_HUMAN	MRPS23	physical	26186194
RT27_HUMAN	MRPS27	physical	26186194
RT06_HUMAN	MRPS6	physical	26186194
RT18B_HUMAN	MRPS18B	physical	26186194
RT10_HUMAN	MRPS10	physical	26186194
RT34_HUMAN	MRPS34	physical	26186194
RT29_HUMAN	DAP3	physical	26186194
RT28_HUMAN	MRPS28	physical	26186194
RT05_HUMAN	MRPS5	physical	26186194
RT18C_HUMAN	MRPS18C	physical	26186194
RT07_HUMAN	MRPS7	physical	26186194
RT22_HUMAN	MRPS22	physical	26186194
RT25_HUMAN	MRPS25	physical	26186194
RT33_HUMAN	MRPS33	physical	26186194
RT11_HUMAN	MRPS11	physical	26186194
RT24_HUMAN	MRPS24	physical	26186194
CDK19_HUMAN	CDK19	physical	26186194
RT14_HUMAN	MRPS14	physical	26186194
RT21_HUMAN	MRPS21	physical	26186194
RT29_HUMAN	DAP3	physical	26344197
RT23_HUMAN	MRPS23	physical	26344197
RT07_HUMAN	MRPS7	physical	26344197
RT09_HUMAN	MRPS9	physical	26344197
PTCD3_HUMAN	PTCD3	physical	26344197
F177A_HUMAN	FAM177A1	physical	28514442
PTCD3_HUMAN	PTCD3	physical	28514442
RT09_HUMAN	MRPS9	physical	28514442
RT27_HUMAN	MRPS27	physical	28514442
CDK19_HUMAN	CDK19	physical	28514442
RT35_HUMAN	MRPS35	physical	28514442
RT05_HUMAN	MRPS5	physical	28514442
RT18B_HUMAN	MRPS18B	physical	28514442
RT33_HUMAN	MRPS33	physical	28514442
RT23_HUMAN	MRPS23	physical	28514442
RT29_HUMAN	DAP3	physical	28514442
RT18C_HUMAN	MRPS18C	physical	28514442
RT21_HUMAN	MRPS21	physical	28514442
RT10_HUMAN	MRPS10	physical	28514442
RT25_HUMAN	MRPS25	physical	28514442
RT26_HUMAN	MRPS26	physical	28514442
RT14_HUMAN	MRPS14	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.