RT34_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RT34_HUMAN
• UniProt AC: P82930
• Protein Name: 28S ribosomal protein S34, mitochondrial
• Gene Name: MRPS34
• Organism: Homo sapiens (Human).
• Sequence Length: 218
• Subcellular Localization: Mitochondrion .
• Protein Description: Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation..
• Protein Sequence: MARKKVRPRLIAELARRVRALREQLNRPRDSQLYAVDYETLTRPFSGRRLPVRAWADVRRESRLLQLLGRLPLFGLGRLVTRKSWLWQHDEPCYWRLTRVRPDYTAQNLDHGKAWGILTFKGKTESEAREIEHVMYHDWRLVPKHEEEAFTAFTPAPEDSLASVPYPPLLRAMIIAERQKNGDTSTEEPMLNVQRIRMEPWDYPAKQEDKGRAKGTPV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
84	O-linked_Glycosylation	GRLVTRKSWLWQHDE CCCCCCCHHHHCCCC	24.90	30620550
104	Phosphorylation	LTRVRPDYTAQNLDH EEEECCCCCCCCCCC	13.47	28152594
105	Phosphorylation	TRVRPDYTAQNLDHG EEECCCCCCCCCCCC	29.19	28152594
121	Ubiquitination	AWGILTFKGKTESEA EEEEEEEECCCHHHH	55.02	21890473
123	Ubiquitination	GILTFKGKTESEARE EEEEEECCCHHHHHH	50.11	-
136	Phosphorylation	REIEHVMYHDWRLVP HHHHHHEECCEEECC	8.78	-
143	Phosphorylation	YHDWRLVPKHEEEAF ECCEEECCCCHHHHC	36.56	-
154	Phosphorylation	EEAFTAFTPAPEDSL HHHCCCCCCCCCCCC	18.97	-
161	Phosphorylation	TPAPEDSLASVPYPP CCCCCCCCCCCCCHH	6.78	-
166	Phosphorylation	DSLASVPYPPLLRAM CCCCCCCCHHHHHHH	18.48	-
184	Phosphorylation	ERQKNGDTSTEEPML HHHHCCCCCCCCCCC	38.66	20068231
185	Phosphorylation	RQKNGDTSTEEPMLN HHHCCCCCCCCCCCC	38.26	26471730
186	Phosphorylation	QKNGDTSTEEPMLNV HHCCCCCCCCCCCCE	46.60	26471730
187	Ubiquitination	KNGDTSTEEPMLNVQ HCCCCCCCCCCCCEE	60.93	-
190	Sulfoxidation	DTSTEEPMLNVQRIR CCCCCCCCCCEEEEE	4.87	21406390

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RT34_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RT34_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RT34_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NINL_HUMAN	NINL	physical	28514442
RT27_HUMAN	MRPS27	physical	28514442
EPDR1_HUMAN	EPDR1	physical	28514442
PSMG4_HUMAN	PSMG4	physical	28514442
DDX55_HUMAN	DDX55	physical	28514442
RT18C_HUMAN	MRPS18C	physical	28514442
NOA1_HUMAN	NOA1	physical	28514442
RT33_HUMAN	MRPS33	physical	28514442
RT31_HUMAN	MRPS31	physical	28514442
RT35_HUMAN	MRPS35	physical	28514442
RT09_HUMAN	MRPS9	physical	28514442
RT29_HUMAN	DAP3	physical	28514442
RT14_HUMAN	MRPS14	physical	28514442
RT21_HUMAN	MRPS21	physical	28514442
RT25_HUMAN	MRPS25	physical	28514442
PTCD3_HUMAN	PTCD3	physical	28514442
RT18B_HUMAN	MRPS18B	physical	28514442
RT02_HUMAN	MRPS2	physical	28514442
PSMG3_HUMAN	PSMG3	physical	28514442
FA92A_HUMAN	FAM92A1	physical	28514442
RT10_HUMAN	MRPS10	physical	28514442
RT28_HUMAN	MRPS28	physical	28514442
RT22_HUMAN	MRPS22	physical	28514442
RT05_HUMAN	MRPS5	physical	28514442
RT15_HUMAN	MRPS15	physical	28514442
RT07_HUMAN	MRPS7	physical	28514442
RT16_HUMAN	MRPS16	physical	28514442
RT06_HUMAN	MRPS6	physical	28514442
H11_HUMAN	HIST1H1A	physical	28514442
RT23_HUMAN	MRPS23	physical	28514442
RT26_HUMAN	MRPS26	physical	28514442
SUV3_HUMAN	SUPV3L1	physical	28514442
ZZEF1_HUMAN	ZZEF1	physical	28514442
PSME3_HUMAN	PSME3	physical	28514442
DEFM_HUMAN	PDF	physical	28514442
NOG2_HUMAN	GNL2	physical	28514442
PPCEL_HUMAN	PREPL	physical	28514442
FABD_HUMAN	MCAT	physical	28514442
IF2B3_HUMAN	IGF2BP3	physical	28514442
IF2B1_HUMAN	IGF2BP1	physical	28514442
F192A_HUMAN	FAM192A	physical	28514442
ZN574_HUMAN	ZNF574	physical	28514442
HECD3_HUMAN	HECTD3	physical	28514442
ZN770_HUMAN	ZNF770	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.