FA92A_HUMAN - dbPTM
FA92A_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FA92A_HUMAN
UniProt AC A1XBS5
Protein Name Protein FAM92A
Gene Name FAM92A {ECO:0000312|HGNC:HGNC:30452}
Organism Homo sapiens (Human).
Sequence Length 289
Subcellular Localization Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body . Weak punctate vesicular distribution throughout the cytoplasm (PubMed:27528616). Localizes at the distal end of m
Protein Description May play a role in ciliogenesis. [PubMed: 27528616 In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis]
Protein Sequence MMRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAATETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMKDIKTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDLEVFRNSLYAPDYSSRLDIVRANSKSPLQRSLSAKCVSGTGQVSTCRLRKDQQAEDDEDDELDVTEEENFLK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
14 (in isoform 5)Ubiquitination-21906983
14 (in isoform 3)Ubiquitination-21906983
14 (in isoform 4)Ubiquitination-21906983
14 (in isoform 1)Ubiquitination-21906983
14 (in isoform 2)Ubiquitination-21906983
14UbiquitinationENRNAQTKQLQTAVS
CHHHHHHHHHHHHHH		21906983
18PhosphorylationAQTKQLQTAVSNVEK
HHHHHHHHHHHHHHH		26270265
21PhosphorylationKQLQTAVSNVEKHFG
HHHHHHHHHHHHHHH		26270265
24UbiquitinationQTAVSNVEKHFGELC
HHHHHHHHHHHHHHH		27667366
30UbiquitinationVEKHFGELCQIFAAY
HHHHHHHHHHHHHHH		27667366
41PhosphorylationFAAYVRKTARLRDKA
HHHHHHHHHHHHHHH		23532336
47UbiquitinationKTARLRDKADLLVNE
HHHHHHHHHHHHHHH		29967540
55UbiquitinationADLLVNEINAYAATE
HHHHHHHHHHHHCCC		27667366
58PhosphorylationLVNEINAYAATETPH
HHHHHHHHHCCCCCC		-
67UbiquitinationATETPHLKLGLMNFA
CCCCCCHHHHHHHHH		32015554
79 (in isoform 2)Ubiquitination-21906983
79UbiquitinationNFADEFAKLQDYRQA
HHHHHHHHHHHHHHH		21906983
79 (in isoform 4)Ubiquitination-21906983
79 (in isoform 3)Ubiquitination-21906983
79 (in isoform 1)Ubiquitination-21906983
79 (in isoform 5)Ubiquitination-21906983
94UbiquitinationEVERLEAKVVEPLKT
HHHHHHHHHHCCCHH		21906983
94 (in isoform 2)Ubiquitination-21906983
94 (in isoform 3)Ubiquitination-21906983
94 (in isoform 4)Ubiquitination-21906983
94 (in isoform 1)Ubiquitination-21906983
100 (in isoform 1)Ubiquitination-21906983
100 (in isoform 2)Ubiquitination-21906983
100UbiquitinationAKVVEPLKTYGTIVK
HHHHCCCHHCCEEEE		21906983
100 (in isoform 3)Ubiquitination-21906983
100 (in isoform 4)Ubiquitination-21906983
101PhosphorylationKVVEPLKTYGTIVKM
HHHCCCHHCCEEEEE		29496907
102PhosphorylationVVEPLKTYGTIVKMK
HHCCCHHCCEEEEEE		29496907
107 (in isoform 2)Ubiquitination-21906983
107UbiquitinationKTYGTIVKMKRDDLK
HHCCEEEEEEHHHHH		2190698
107 (in isoform 3)Ubiquitination-21906983
107 (in isoform 1)Ubiquitination-21906983
107 (in isoform 4)Ubiquitination-21906983
114UbiquitinationKMKRDDLKATLTARN
EEEHHHHHHHHHHHH		29967540
125UbiquitinationTARNREAKQLTQLER
HHHHHHHHHHHHHHH		27667366
139PhosphorylationRTRQRNPSDRHVISQ
HHHHHCHHHHHHHHH		28985074
172UbiquitinationLEETINNFERQKMKD
HHHHHHHHHHHHHHH		27667366
204UbiquitinationKALEVYTAAYQNIQN
HHHHHHHHHHHHHCC		27667366
214UbiquitinationQNIQNIDEDEDLEVF
HHHCCCCCCCCHHHH		32015554
226PhosphorylationEVFRNSLYAPDYSSR
HHHHHCCCCCCCHHH		27642862
229UbiquitinationRNSLYAPDYSSRLDI
HHCCCCCCCHHHHHH		29967540
230PhosphorylationNSLYAPDYSSRLDIV
HCCCCCCCHHHHHHH		27642862
231PhosphorylationSLYAPDYSSRLDIVR
CCCCCCCHHHHHHHH		27642862
232PhosphorylationLYAPDYSSRLDIVRA
CCCCCCHHHHHHHHC		27642862
241PhosphorylationLDIVRANSKSPLQRS
HHHHHCCCCCHHHHH		22199227
242UbiquitinationDIVRANSKSPLQRSL
HHHHCCCCCHHHHHH		27667366
243PhosphorylationIVRANSKSPLQRSLS
HHHCCCCCHHHHHHH		22199227
248PhosphorylationSKSPLQRSLSAKCVS
CCCHHHHHHHCCCCC		29514088
250PhosphorylationSPLQRSLSAKCVSGT
CHHHHHHHCCCCCCC		29514088
252UbiquitinationLQRSLSAKCVSGTGQ
HHHHHHCCCCCCCCC		32015554
267UbiquitinationVSTCRLRKDQQAEDD
EEEEEECCCCCCCCC		29967540
282PhosphorylationEDDELDVTEEENFLK
CCCCCCCCHHHHCCC		23403867
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FA92A_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FA92A_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FA92A_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
APBP2_HUMANAPPBP2physical
19060904
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FA92A_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory