ZN770_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN770_HUMAN
• UniProt AC: Q6IQ21
• Protein Name: Zinc finger protein 770
• Gene Name: ZNF770
• Organism: Homo sapiens (Human).
• Sequence Length: 691
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQGKVVALDSVM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Sumoylation	ENNLKMLKIQQCVVA HHHHHEEHHHHHHHH	34.66	28112733
27	Phosphorylation	KLPRNRPYVCNICFK CCCCCCCEEEEEECH	17.88	22210691
38	Phosphorylation	ICFKHFETPSKLARH EECHHCCCHHHHHHH	31.73	22210691
50	Phosphorylation	ARHYLIHTGQKPFEC HHHHHHHCCCCCCCC	34.02	-
63	Phosphorylation	ECDVCHKTFRQLVHL CCCCHHHHHHHHHHH	10.61	22210691
76	Phosphorylation	HLERHQLTHSLPFKC HHHHHHCCCCCCCCC	11.66	22210691
78	Phosphorylation	ERHQLTHSLPFKCSI HHHHCCCCCCCCCHH	32.28	28450419
84	Phosphorylation	HSLPFKCSICQRHFK CCCCCCCHHHHHHHC	27.30	22210691
112	Sumoylation	ETYQNNVKQVRRLLE HHHHHHHHHHHHHHH	45.24	28112733
112	Ubiquitination	ETYQNNVKQVRRLLE HHHHHHHHHHHHHHH	45.24	29967540
121	Sumoylation	VRRLLEAKQEKSMYG HHHHHHHHHHHHHHC	50.00	28112733
121	Ubiquitination	VRRLLEAKQEKSMYG HHHHHHHHHHHHHHC	50.00	29967540
124	Ubiquitination	LLEAKQEKSMYGVYN HHHHHHHHHHHCCCC	37.72	29967540
132	Phosphorylation	SMYGVYNTFTTEERW HHHCCCCCCCCHHHE	12.50	-
146	Sumoylation	WALHPCSKSDPMYSM EECCCCCCCCCCCCC	66.64	28112733
151	Phosphorylation	CSKSDPMYSMKRRKN CCCCCCCCCCCCCCC	15.82	-
154	Ubiquitination	SDPMYSMKRRKNIHA CCCCCCCCCCCCCCE	43.01	29967540
226	Ubiquitination	CFCQKGFKIQSKLLK CEECCCCCCHHHHHH	48.80	29967540
262	Sumoylation	ESRPLPNKLNANQGG CCCCCCCCCCCCCCC	40.97	28112733
330	Phosphorylation	PSRFKRSYNYKTIVK CCHHCCCCCHHHHHH	26.92	22817900
332	Phosphorylation	RFKRSYNYKTIVKKI HHCCCCCHHHHHHHH	10.98	27762562
333	Ubiquitination	FKRSYNYKTIVKKIL HCCCCCHHHHHHHHH	28.30	29967540
333	Sumoylation	FKRSYNYKTIVKKIL HCCCCCHHHHHHHHH	28.30	-
333	Sumoylation	FKRSYNYKTIVKKIL HCCCCCHHHHHHHHH	28.30	-
350	Sumoylation	LKRARSKKLDNFQSE HHHHHHHCCCCHHHH	63.42	-
350	Ubiquitination	LKRARSKKLDNFQSE HHHHHHHCCCCHHHH	63.42	29967540
350	Sumoylation	LKRARSKKLDNFQSE HHHHHHHCCCCHHHH	63.42	-
358	Acetylation	LDNFQSEKKVFKKSF CCCHHHHHHHHHHHH	60.53	24468157
358	Ubiquitination	LDNFQSEKKVFKKSF CCCHHHHHHHHHHHH	60.53	29967540
364	Phosphorylation	EKKVFKKSFLRNCDL HHHHHHHHHHHCCCC	30.06	24719451
373	Phosphorylation	LRNCDLISGEQSSEQ HHCCCCCCCCCCCHH	43.50	-
377	Phosphorylation	DLISGEQSSEQTQRT CCCCCCCCCHHHHHH	31.38	-
388	Phosphorylation	TQRTFVGSLGKHGTY HHHHCCHHHHCCCEE	28.75	24173317
391	Sumoylation	TFVGSLGKHGTYKTI HCCHHHHCCCEEEEE	44.12	-
391	Ubiquitination	TFVGSLGKHGTYKTI HCCHHHHCCCEEEEE	44.12	29967540
391	Sumoylation	TFVGSLGKHGTYKTI HCCHHHHCCCEEEEE	44.12	-
396	Ubiquitination	LGKHGTYKTIGNRKK HHCCCEEEEECCCCC	33.24	29967540
407	Phosphorylation	NRKKKTLTLPFSWQN CCCCCEEEECCCHHC	37.30	-
417	Ubiquitination	FSWQNMGKNLKGILT CCHHCCCCCCCCEEE	48.62	29967540
420	Sumoylation	QNMGKNLKGILTTEN HCCCCCCCCEEECCC	53.98	28112733
424	Phosphorylation	KNLKGILTTENILSI CCCCCEEECCCCHHC	30.09	-
425	Phosphorylation	NLKGILTTENILSID CCCCEEECCCCHHCC	24.48	-
430	Phosphorylation	LTTENILSIDNSVNK EECCCCHHCCCCCCC	24.89	-
434	Phosphorylation	NILSIDNSVNKKDLS CCHHCCCCCCCCCCC	24.26	23532336
437	Ubiquitination	SIDNSVNKKDLSICG HCCCCCCCCCCCCCC	45.57	29967540
437	Sumoylation	SIDNSVNKKDLSICG HCCCCCCCCCCCCCC	45.57	28112733
462	Phosphorylation	EVLQCGFSVPRENIR EEEECCCCCCHHHHC	19.25	-
489	Ubiquitination	KVFPSISKLKRHYLI HHCCCHHHHHHEEEE	57.25	29967540
498	Phosphorylation	KRHYLIHTGQRPFGC HHEEEEECCCCCCCC	28.19	-
511	Phosphorylation	GCNICGKSFRQSAHL CCCCCCHHHHHHHHH	15.79	24719451
515	Phosphorylation	CGKSFRQSAHLKRHE CCHHHHHHHHHHHHH	17.25	30622161
519	Acetylation	FRQSAHLKRHEQTHN HHHHHHHHHHHHHCC	41.67	12431569
569	Phosphorylation	QAPGVQKYEVSESDQ CCCCCEEEEECCHHH	12.41	28450419
572	Phosphorylation	GVQKYEVSESDQMSG CCEEEEECCHHHCCC	21.31	28450419
574	Phosphorylation	QKYEVSESDQMSGVK EEEEECCHHHCCCCE	26.15	28450419
578	Phosphorylation	VSESDQMSGVKAESQ ECCHHHCCCCEECCC	34.50	28450419
633	Phosphorylation	RCSVCAKSFRSPSKL EHHHHHHHCCCHHHH	13.84	28102081
636	Phosphorylation	VCAKSFRSPSKLERH HHHHHCCCHHHHHHE	31.36	29514088
638	Phosphorylation	AKSFRSPSKLERHYL HHHCCCHHHHHHEEE	51.63	29514088
683	Sumoylation	FKERPQGKVVALDSV CCCCCCCCEEEEECC	28.43	28112733

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN770_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN770_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN770_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN770_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.