RT11_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RT11_HUMAN
• UniProt AC: P82912
• Protein Name: 28S ribosomal protein S11, mitochondrial
• Gene Name: MRPS11
• Organism: Homo sapiens (Human).
• Sequence Length: 194
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MQAVRNAGSRFLRSWTWPQTAGRVVARTPAGTICTGARQLQDAAAKQKVEQNAAPSHTKFSIYPPIPGEESSLRWAGKKFEEIPIAHIKASHNNTQIQVVSASNEPLAFASCGTEGFRNAKKGTGIAAQTAGIAAAARAKQKGVIHIRVVVKGLGPGRLSAMHGLIMGGLEVISITDNTPIPHNGCRPRKARKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	AGSRFLRSWTWPQTA CCHHHHHHCCCCCCC	30.88	26074081
16	Phosphorylation	SRFLRSWTWPQTAGR HHHHHHCCCCCCCCC	28.63	26074081
16 (in isoform 2)	Phosphorylation	-	28.63	-
20	Phosphorylation	RSWTWPQTAGRVVAR HHCCCCCCCCCEEEE	27.31	26074081
20	O-linked_Glycosylation	RSWTWPQTAGRVVAR HHCCCCCCCCCEEEE	27.31	30379171
43	Ubiquitination	GARQLQDAAAKQKVE HHHHHHHHHHHHHHH	9.07	22817900
44	Ubiquitination	ARQLQDAAAKQKVEQ HHHHHHHHHHHHHHH	24.39	21890473
48	Acetylation	QDAAAKQKVEQNAAP HHHHHHHHHHHCCCC	47.21	25953088
58 (in isoform 2)	Ubiquitination	-	37.82	21890473
58	Ubiquitination	QNAAPSHTKFSIYPP HCCCCCCCCEEECCC	37.82	21890473
59	Ubiquitination	NAAPSHTKFSIYPPI CCCCCCCCEEECCCC	31.52	21890473
59	Acetylation	NAAPSHTKFSIYPPI CCCCCCCCEEECCCC	31.52	25953088
59 (in isoform 1)	Ubiquitination	-	31.52	21890473
61	Phosphorylation	APSHTKFSIYPPIPG CCCCCCEEECCCCCC	23.83	26074081
63	Phosphorylation	SHTKFSIYPPIPGEE CCCCEEECCCCCCCC	11.19	26074081
71	Phosphorylation	PPIPGEESSLRWAGK CCCCCCCCCCCCCCC	30.30	26074081
77	Ubiquitination	ESSLRWAGKKFEEIP CCCCCCCCCCCCCCC	27.08	22817900
78	Ubiquitination	SSLRWAGKKFEEIPI CCCCCCCCCCCCCCE	46.68	21890473
78 (in isoform 2)	Ubiquitination	-	46.68	21890473
79	Ubiquitination	SLRWAGKKFEEIPIA CCCCCCCCCCCCCEE	58.03	21890473
79 (in isoform 1)	Ubiquitination	-	58.03	21890473
79	Acetylation	SLRWAGKKFEEIPIA CCCCCCCCCCCCCEE	58.03	25953088
86	Ubiquitination	KFEEIPIAHIKASHN CCCCCCEEEEEECCC	7.94	21890473
87	Ubiquitination	FEEIPIAHIKASHNN CCCCCEEEEEECCCC	23.85	21890473
88 (in isoform 3)	Ubiquitination	-	2.70	21890473
88	Ubiquitination	EEIPIAHIKASHNNT CCCCEEEEEECCCCC	2.70	21890473
89	Ubiquitination	EIPIAHIKASHNNTQ CCCEEEEEECCCCCE	33.69	21890473
89 (in isoform 3)	Ubiquitination	-	33.69	21890473
117	Ubiquitination	ASCGTEGFRNAKKGT EECCCCHHHHCCCCC	4.42	21890473
119 (in isoform 3)	Ubiquitination	-	54.58	21890473
119	Ubiquitination	CGTEGFRNAKKGTGI CCCCHHHHCCCCCCH	54.58	21890473
120	Ubiquitination	GTEGFRNAKKGTGIA CCCHHHHCCCCCCHH	15.64	21890473
120 (in isoform 2)	Ubiquitination	-	15.64	21890473
121 (in isoform 1)	Ubiquitination	-	56.11	21890473
121 (in isoform 2)	Ubiquitination	-	56.11	21890473
121	Ubiquitination	TEGFRNAKKGTGIAA CCHHHHCCCCCCHHH	56.11	21890473
122 (in isoform 1)	Ubiquitination	-	60.33	21890473
122	Ubiquitination	EGFRNAKKGTGIAAQ CHHHHCCCCCCHHHH	60.33	21890473
124	Phosphorylation	FRNAKKGTGIAAQTA HHHCCCCCCHHHHHH	34.00	20068231
130	Phosphorylation	GTGIAAQTAGIAAAA CCCHHHHHHHHHHHH	23.33	20068231
151	Ubiquitination	VIHIRVVVKGLGPGR EEEEEEEECCCCCCH	3.58	21890473
151 (in isoform 2)	Ubiquitination	-	3.58	21890473
152 (in isoform 1)	Ubiquitination	-	36.49	21890473
152	Ubiquitination	IHIRVVVKGLGPGRL EEEEEEECCCCCCHH	36.49	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RT11_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RT11_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RT11_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RT14_HUMAN	MRPS14	physical	22939629
SAM50_HUMAN	SAMM50	physical	22939629
RT09_HUMAN	MRPS9	physical	26186194
CUL4A_HUMAN	CUL4A	physical	26186194
PTCD3_HUMAN	PTCD3	physical	26186194
IF2M_HUMAN	MTIF2	physical	26186194
DCAF5_HUMAN	DCAF5	physical	26186194
RT22_HUMAN	MRPS22	physical	26186194
WDTC1_HUMAN	WDTC1	physical	26186194
DDA1_HUMAN	DDA1	physical	26186194
PCMD1_HUMAN	PCMTD1	physical	26186194
PCMD2_HUMAN	PCMTD2	physical	26186194
RT18C_HUMAN	MRPS18C	physical	26186194
NOA1_HUMAN	NOA1	physical	28514442
DCAF5_HUMAN	DCAF5	physical	28514442
PCMD1_HUMAN	PCMTD1	physical	28514442
WDTC1_HUMAN	WDTC1	physical	28514442
TNIK_HUMAN	TNIK	physical	28514442
RT15_HUMAN	MRPS15	physical	28514442
NC2A_HUMAN	DRAP1	physical	28514442
RT34_HUMAN	MRPS34	physical	28514442
RT09_HUMAN	MRPS9	physical	28514442
RT18C_HUMAN	MRPS18C	physical	28514442
RT31_HUMAN	MRPS31	physical	28514442
SUV3_HUMAN	SUPV3L1	physical	28514442
RT27_HUMAN	MRPS27	physical	28514442
RT05_HUMAN	MRPS5	physical	28514442
RT21_HUMAN	MRPS21	physical	28514442
PTCD3_HUMAN	PTCD3	physical	28514442
RT35_HUMAN	MRPS35	physical	28514442
RT29_HUMAN	DAP3	physical	28514442
RBM12_HUMAN	RBM12	physical	28514442
RT33_HUMAN	MRPS33	physical	28514442
AFAD_HUMAN	MLLT4	physical	28514442
EDC4_HUMAN	EDC4	physical	28514442
RT07_HUMAN	MRPS7	physical	28514442
TPD52_HUMAN	TPD52	physical	28514442
FNTB_HUMAN	FNTB	physical	28514442
ZC3H4_HUMAN	ZC3H4	physical	28514442
NAA16_HUMAN	NAA16	physical	28514442
RT18B_HUMAN	MRPS18B	physical	28514442
TCEA1_HUMAN	TCEA1	physical	28514442
RCBT2_HUMAN	RCBTB2	physical	28514442
RT02_HUMAN	MRPS2	physical	28514442
RT26_HUMAN	MRPS26	physical	28514442
NAA15_HUMAN	NAA15	physical	28514442
LETM1_HUMAN	LETM1	physical	28514442
RPR1A_HUMAN	RPRD1A	physical	28514442
RT14_HUMAN	MRPS14	physical	28514442
DDA1_HUMAN	DDA1	physical	28514442
PSMF1_HUMAN	PSMF1	physical	28514442
RT25_HUMAN	MRPS25	physical	28514442
ODB2_HUMAN	DBT	physical	28514442
CUL4A_HUMAN	CUL4A	physical	28514442
DDX55_HUMAN	DDX55	physical	28514442
ERF1_HUMAN	ETF1	physical	28514442
RS8_HUMAN	RPS8	physical	28514442
NB5R3_HUMAN	CYB5R3	physical	28514442
RT28_HUMAN	MRPS28	physical	28514442
HNRPR_HUMAN	HNRNPR	physical	28514442
CUL4B_HUMAN	CUL4B	physical	28514442
FABD_HUMAN	MCAT	physical	28514442
RT23_HUMAN	MRPS23	physical	28514442
TRUA_HUMAN	PUS1	physical	28514442
RT10_HUMAN	MRPS10	physical	28514442
SRP54_HUMAN	SRP54	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.