| UniProt ID | PCMD1_HUMAN | |
|---|---|---|
| UniProt AC | Q96MG8 | |
| Protein Name | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 | |
| Gene Name | PCMTD1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 357 | |
| Subcellular Localization |
Cytoplasm. Membrane Lipid-anchor . |
|
| Protein Description | ||
| Protein Sequence | MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Myristoylation | ------MGGAVSAGE ------CCCCCCCCC | 32.54 | 25807930 | |
| 19 | Ubiquitination | DDLIDNLKEAQYIRT HHHHHHHHHHHHHCH | 58.20 | - | |
| 41 | Phosphorylation | RAIDRGDYYLEGYRD HHHHCCCHHCCCCCC | 16.87 | - | |
| 42 | Phosphorylation | AIDRGDYYLEGYRDN HHHCCCHHCCCCCCC | 11.74 | - | |
| 46 | Phosphorylation | GDYYLEGYRDNAYKD CCHHCCCCCCCHHHH | 12.86 | - | |
| 51 | Phosphorylation | EGYRDNAYKDLAWKH CCCCCCHHHHHHHHC | 15.99 | - | |
| 52 | Ubiquitination | GYRDNAYKDLAWKHG CCCCCHHHHHHHHCC | 43.80 | - | |
| 124 | Ubiquitination | VVEYAKEKLESFIKN HHHHHHHHHHHHHHC | 57.77 | - | |
| 127 | Phosphorylation | YAKEKLESFIKNSDS HHHHHHHHHHHCCCC | 42.58 | 24719451 | |
| 171 | Ubiquitination | YCGAGVQKDHENYMK ECCCCCCCCHHHHHH | 59.66 | - | |
| 178 | Ubiquitination | KDHENYMKILLKVGG CCHHHHHHHHHHCCC | 21.60 | - | |
| 209 | Ubiquitination | GQNTWESKNILAVSF CCCCCCCCCEEEEEE | 36.17 | - | |
| 302 | Phosphorylation | LIPQPLDSEEDEKME ECCCCCCHHHHHHHH | 51.04 | 22617229 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PCMD1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PCMD1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PCMD1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PCMD1_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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