dbPTM

CSN6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CSN6_HUMAN
UniProt AC	Q7L5N1
Protein Name	COP9 signalosome complex subunit 6
Gene Name	COPS6
Organism	Homo sapiens (Human).
Sequence Length	327
Subcellular Localization	Nucleus. Cytoplasm. The interaction with HIV-1 Vpr protein possibly leads its translocation to a perinuclear region.
Protein Description	Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity. Stabilizes COP1 through reducing COP1 auto-ubiquitination and decelerating COP1 turnover rate, hence regulates the ubiquitination of COP1 targets..
Protein Sequence	MAAAAAAAAATNGTGGSSGMEVDAAVVPSVMACGVTGSVSVALHPLVILNISDHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKIIIDKEYYYTKEEQFKQVFKELEFLGWYTTGGPPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTDLPVSVFESVIDIINGEATMLFAELTYTLATEEAERIGVDHVARMTATGSGENSTVAEHLIAQHSAIKMLHSRVKLILEYVKASEAGEVPFNHEILREAYALCHCLPVLSTDKFKTDFYDQCNDVGLMAYLGTITKTCNTMNQFVNKFNVLYDRQGIGRRMRGLFF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	AAAAAAATNGTGGSS HHHHHHHHCCCCCCC	29.47	22210691
14	Phosphorylation	AAAATNGTGGSSGME HHHHHCCCCCCCCCC	40.20	22210691
17	Phosphorylation	ATNGTGGSSGMEVDA HHCCCCCCCCCCCCC	25.68	22210691
18	Phosphorylation	TNGTGGSSGMEVDAA HCCCCCCCCCCCCCC	45.49	22210691
36	Phosphorylation	SVMACGVTGSVSVAL CEECCCCCCCHHHHC	14.71	22210691
38	Phosphorylation	MACGVTGSVSVALHP ECCCCCCCHHHHCCC	11.23	22210691
40	Phosphorylation	CGVTGSVSVALHPLV CCCCCCHHHHCCCEE	11.90	22210691
60	Phosphorylation	DHWIRMRSQEGRPVQ HHHHHHHCCCCCCCE	24.20	29396449
75	Ubiquitination	VIGALIGKQEGRNIE EEEEEECCCCCCCEE	37.88	21906983
97	Ubiquitination	LSHTVEEKIIIDKEY HHCCCEEEEEECHHH	26.21	22817900
102	Ubiquitination	EEKIIIDKEYYYTKE EEEEEECHHHHCCCH	36.89	21890473
102	2-Hydroxyisobutyrylation	EEKIIIDKEYYYTKE EEEEEECHHHHCCCH	36.89	-
102	Ubiquitination	EEKIIIDKEYYYTKE EEEEEECHHHHCCCH	36.89	27667366
105	Phosphorylation	IIIDKEYYYTKEEQF EEECHHHHCCCHHHH	13.02	22817900
106	Phosphorylation	IIDKEYYYTKEEQFK EECHHHHCCCHHHHH	15.50	22817900
108	Ubiquitination	DKEYYYTKEEQFKQV CHHHHCCCHHHHHHH	43.03	21906983
108	Acetylation	DKEYYYTKEEQFKQV CHHHHCCCHHHHHHH	43.03	26822725
108	2-Hydroxyisobutyrylation	DKEYYYTKEEQFKQV CHHHHCCCHHHHHHH	43.03	-
113	Ubiquitination	YTKEEQFKQVFKELE CCCHHHHHHHHHHHH	45.29	27667366
117	Ubiquitination	EQFKQVFKELEFLGW HHHHHHHHHHHHCCC	63.63	22817900
117	Ubiquitination	EQFKQVFKELEFLGW HHHHHHHHHHHHCCC	63.63	21890473
143	S-nitrosylation	IHVHKQVCEIIESPL CHHHHHHHHHHCCCE	2.62	19483679
143	S-nitrosocysteine	IHVHKQVCEIIESPL CHHHHHHHHHHCCCE	2.62	-
148	Phosphorylation	QVCEIIESPLFLKLN HHHHHHCCCEEEECC	19.25	27050516
153	Ubiquitination	IESPLFLKLNPMTKH HCCCEEEECCCCCCC	38.59	21963094
207	Phosphorylation	VDHVARMTATGSGEN CCEEEEEEECCCCCC	18.60	26074081
209	Phosphorylation	HVARMTATGSGENST EEEEEEECCCCCCCH	23.78	26074081
211	Phosphorylation	ARMTATGSGENSTVA EEEEECCCCCCCHHH	38.28	26074081
215	Phosphorylation	ATGSGENSTVAEHLI ECCCCCCCHHHHHHH	21.69	26074081
216	Phosphorylation	TGSGENSTVAEHLIA CCCCCCCHHHHHHHH	35.00	26074081
229	Ubiquitination	IAQHSAIKMLHSRVK HHHHHHHHHHHHHHH	34.82	-
236	Ubiquitination	KMLHSRVKLILEYVK HHHHHHHHHHHHHHH	28.79	21890473
236	Ubiquitination	KMLHSRVKLILEYVK HHHHHHHHHHHHHHH	28.79	22817900
241	Phosphorylation	RVKLILEYVKASEAG HHHHHHHHHHHHHCC	12.10	20068231
243	Ubiquitination	KLILEYVKASEAGEV HHHHHHHHHHHCCCC	45.34	21906983
243	Ubiquitination	KLILEYVKASEAGEV HHHHHHHHHHHCCCC	45.34	21890473
245	Phosphorylation	ILEYVKASEAGEVPF HHHHHHHHHCCCCCC	23.43	23532336
261	Phosphorylation	HEILREAYALCHCLP HHHHHHHHHHHHHHH	8.71	28152594
271	Phosphorylation	CHCLPVLSTDKFKTD HHHHHHCCCCHHCCC	34.49	23532336
274	Ubiquitination	LPVLSTDKFKTDFYD HHHCCCCHHCCCCHH	49.18	22505724
274	Acetylation	LPVLSTDKFKTDFYD HHHCCCCHHCCCCHH	49.18	25953088
276	Ubiquitination	VLSTDKFKTDFYDQC HCCCCHHCCCCHHHH	53.58	29967540
280	Phosphorylation	DKFKTDFYDQCNDVG CHHCCCCHHHHCHHH	14.12	-
294	Phosphorylation	GLMAYLGTITKTCNT HHHHHHHHHHHHHHH	23.91	28387310
297	Ubiquitination	AYLGTITKTCNTMNQ HHHHHHHHHHHHHHH	47.43	21963094
298	Phosphorylation	YLGTITKTCNTMNQF HHHHHHHHHHHHHHH	11.44	-
301	Phosphorylation	TITKTCNTMNQFVNK HHHHHHHHHHHHHHH	21.46	-
308	Acetylation	TMNQFVNKFNVLYDR HHHHHHHHHCHHHCC	32.77	26051181
308	Ubiquitination	TMNQFVNKFNVLYDR HHHHHHHHHCHHHCC	32.77	21890473
308	Ubiquitination	TMNQFVNKFNVLYDR HHHHHHHHHCHHHCC	32.77	21906983
313	Phosphorylation	VNKFNVLYDRQGIGR HHHHCHHHCCCCCCH	12.56	-
315	Methylation	KFNVLYDRQGIGRRM HHCHHHCCCCCCHHH	24.06	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
60	S	Phosphorylation	Kinase	AKT1	P31749	PSP
148	S	Phosphorylation	Kinase	MAPK1	P28482	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CSN6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CSN6_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ERCC8_HUMAN	ERCC8	physical	19615732
CKS1_HUMAN	CKS1B	physical	19615732
DDB2_HUMAN	DDB2	physical	19615732
CSN1_HUMAN	GPS1	physical	19615732
NEDD8_HUMAN	NEDD8	physical	19615732
SKP2_HUMAN	SKP2	physical	19615732
ELOC_HUMAN	TCEB1	physical	19615732
UCHL3_HUMAN	UCHL3	physical	19615732
CUL5_HUMAN	CUL5	physical	19615732
CUL4B_HUMAN	CUL4B	physical	19615732
CUL4A_HUMAN	CUL4A	physical	19615732
CUL3_HUMAN	CUL3	physical	19615732
CUL2_HUMAN	CUL2	physical	19615732
CUL1_HUMAN	CUL1	physical	19615732
CSN3_HUMAN	COPS3	physical	19615732
CSN2_HUMAN	COPS2	physical	19615732
LRC14_HUMAN	LRRC14	physical	19615732
DCAF1_HUMAN	VPRBP	physical	19615732
FEM1B_HUMAN	FEM1B	physical	19615732
CSN8_HUMAN	COPS8	physical	19615732
CSN5_HUMAN	COPS5	physical	19615732
KLH18_HUMAN	KLHL18	physical	19615732
FBX7_HUMAN	FBXO7	physical	19615732
DCAF4_HUMAN	DCAF4	physical	19615732
FBX22_HUMAN	FBXO22	physical	19615732
KLH20_HUMAN	KLHL20	physical	19615732
CSN7A_HUMAN	COPS7A	physical	19615732
KCTD3_HUMAN	KCTD3	physical	19615732
CSN4_HUMAN	COPS4	physical	19615732
CRBN_HUMAN	CRBN	physical	19615732
DTL_HUMAN	DTL	physical	19615732
BTBD1_HUMAN	BTBD1	physical	19615732
KLH24_HUMAN	KLHL24	physical	19615732
BTBD2_HUMAN	BTBD2	physical	19615732
KLHL9_HUMAN	KLHL9	physical	19615732
KLH42_HUMAN	KLHL42	physical	19615732
KLHL8_HUMAN	KLHL8	physical	19615732
CSN7B_HUMAN	COPS7B	physical	19615732
DDA1_HUMAN	DDA1	physical	19615732
ZY11B_HUMAN	ZYG11B	physical	19615732
FBX11_HUMAN	FBXO11	physical	19615732
KLH15_HUMAN	KLHL15	physical	19615732
DCA11_HUMAN	DCAF11	physical	19615732
CLPB_HUMAN	CLPB	physical	19615732
FBXW9_HUMAN	FBXW9	physical	19615732
KLH22_HUMAN	KLHL22	physical	19615732
KLH13_HUMAN	KLHL13	physical	19615732
SHKB1_HUMAN	SHKBP1	physical	19615732
FBX44_HUMAN	FBXO44	physical	19615732
BTBD9_HUMAN	BTBD9	physical	19615732
FBX17_HUMAN	FBXO17	physical	19615732
LLR1_HUMAN	LRR1	physical	19615732
CSN9_HUMAN	MYEOV2	physical	19615732
TOIP2_HUMAN	TOR1AIP2	physical	19615732
IFG15_HUMAN	TOR1AIP2	physical	19615732
CSN7A_HUMAN	COPS7A	physical	19141280
CP110_HUMAN	CCP110	physical	21145461
CSN4_HUMAN	COPS4	physical	21145461
CSN5_HUMAN	COPS5	physical	21145461
CSN1_HUMAN	GPS1	physical	21145461
CUL2_HUMAN	CUL2	physical	21145461
CSN7A_HUMAN	COPS7A	physical	21145461
CSN3_HUMAN	COPS3	physical	21145461
CUL1_HUMAN	CUL1	physical	21145461
CCNA2_HUMAN	CCNA2	physical	21145461
CDK2_HUMAN	CDK2	physical	21145461
CUL4A_HUMAN	CUL4A	physical	21145461
DCAF4_HUMAN	DCAF4	physical	21145461
APBP2_HUMAN	APPBP2	physical	21145461
DCAF1_HUMAN	VPRBP	physical	21145461
FBX17_HUMAN	FBXO17	physical	21145461
CSN6_HUMAN	COPS6	physical	21145461
BTBD2_HUMAN	BTBD2	physical	21145461
CSN2_HUMAN	COPS2	physical	21145461
CUL4B_HUMAN	CUL4B	physical	21145461
FBX11_HUMAN	FBXO11	physical	21145461
CKS1_HUMAN	CKS1B	physical	21145461
DCA11_HUMAN	DCAF11	physical	21145461
DDB2_HUMAN	DDB2	physical	21145461
DCA12_HUMAN	DCAF12	physical	21145461
SKP2_HUMAN	SKP2	physical	21145461
LLR1_HUMAN	LRR1	physical	21145461
FBX7_HUMAN	FBXO7	physical	21145461
FEM1B_HUMAN	FEM1B	physical	21145461
FBX21_HUMAN	FBXO21	physical	21145461
FBXW9_HUMAN	FBXW9	physical	21145461
ERCC8_HUMAN	ERCC8	physical	21145461
KLH42_HUMAN	KLHL42	physical	21145461
KLH18_HUMAN	KLHL18	physical	21145461
DDB1_HUMAN	DDB1	physical	21145461
BTBD1_HUMAN	BTBD1	physical	21145461
RN138_HUMAN	RNF138	physical	21145461
DC4L1_HUMAN	DCAF4L1	physical	21145461
DTL_HUMAN	DTL	physical	21145461
FXL14_HUMAN	FBXL14	physical	21145461
FBX44_HUMAN	FBXO44	physical	21145461
RHBT1_HUMAN	RHOBTB1	physical	21145461
CSN7B_HUMAN	COPS7B	physical	21145461
KLH15_HUMAN	KLHL15	physical	21145461
CSN8_HUMAN	COPS8	physical	21145461
CUL3_HUMAN	CUL3	physical	21145461
CUL5_HUMAN	CUL5	physical	21145461
DCA16_HUMAN	DCAF16	physical	21145461
CSN9_HUMAN	MYEOV2	physical	21145461
CCNA1_HUMAN	CCNA1	physical	21145461
DDA1_HUMAN	DDA1	physical	21145461
KLHL9_HUMAN	KLHL9	physical	21145461
LRC14_HUMAN	LRRC14	physical	21145461
TOIP2_HUMAN	TOR1AIP2	physical	21145461
IFG15_HUMAN	TOR1AIP2	physical	21145461
KLH13_HUMAN	KLHL13	physical	21145461
CDK3_HUMAN	CDK3	physical	21145461
SORL_HUMAN	SORL1	physical	21145461
KLHL8_HUMAN	KLHL8	physical	21145461
SKP1_HUMAN	SKP1	physical	21145461
ELOB_HUMAN	TCEB2	physical	21145461
CPSF1_HUMAN	CPSF1	physical	21145461
BTBD9_HUMAN	BTBD9	physical	21145461
NEDD8_HUMAN	NEDD8	physical	21145461
AMOL2_HUMAN	AMOTL2	physical	21145461
ATP9A_HUMAN	ATP9A	physical	21145461
BACH2_HUMAN	BACH2	physical	21145461
COA1_HUMAN	COA1	physical	21145461
CAPR2_HUMAN	CAPRIN2	physical	21145461
CWC25_HUMAN	CWC25	physical	21145461
CENPF_HUMAN	CENPF	physical	21145461
FXL15_HUMAN	FBXL15	physical	21145461
FOXI1_HUMAN	FOXI1	physical	21145461
KI2S1_HUMAN	KIR2DS1	physical	21145461
KI2LA_HUMAN	KIR2DS1	physical	21145461
KNG1_HUMAN	KNG1	physical	21145461
KSR2_HUMAN	KSR2	physical	21145461
FSBP_HUMAN	RAD54B	physical	21145461
RA54B_HUMAN	RAD54B	physical	21145461
MBTD1_HUMAN	MBTD1	physical	21145461
RIBC2_HUMAN	RIBC2	physical	21145461
RPGR_HUMAN	RPGR	physical	21145461
SCG2_HUMAN	SCG2	physical	21145461
ZMAT2_HUMAN	ZMAT2	physical	21145461
FBX42_HUMAN	FBXO42	physical	21145461
DMBT1_HUMAN	DMBT1	physical	21145461
EHBP1_HUMAN	EHBP1	physical	21145461
FXL18_HUMAN	FBXL18	physical	21145461
MYPT2_HUMAN	PPP1R12B	physical	21145461
PRI1_HUMAN	PRIM1	physical	21145461
RSF1_HUMAN	RSF1	physical	21145461
SNX4_HUMAN	SNX4	physical	21145461
SYNEM_HUMAN	SYNM	physical	21145461
DC122_HUMAN	DCAF12L2	physical	21145461
HEMH_HUMAN	FECH	physical	21145461
KLH12_HUMAN	KLHL12	physical	21145461
FXL12_HUMAN	FBXL12	physical	21145461
KCD18_HUMAN	KCTD18	physical	21145461
KCTD7_HUMAN	KCTD7	physical	21145461
CDK4_HUMAN	CDK4	physical	21145461
LRC47_HUMAN	LRRC47	physical	21145461
RAE1L_HUMAN	RAE1	physical	21145461
K1C10_HUMAN	KRT10	physical	21145461
UBC12_HUMAN	UBE2M	physical	21145461
K2C1_HUMAN	KRT1	physical	21145461
K22E_HUMAN	KRT2	physical	21145461
ELOC_HUMAN	TCEB1	physical	21145461
BACD3_HUMAN	KCTD10	physical	21145461
KLH22_HUMAN	KLHL22	physical	21145461
PDD2L_HUMAN	PDCD2L	physical	21145461
HSP7C_HUMAN	HSPA8	physical	21145461
RL22L_HUMAN	RPL22L1	physical	21145461
TFG_HUMAN	TFG	physical	21145461
LARP4_HUMAN	LARP4	physical	21145461
SMC3_HUMAN	SMC3	physical	21145461
UBC_HUMAN	UBC	physical	21145461
DPOD1_HUMAN	POLD1	physical	21145461
EWS_HUMAN	EWSR1	physical	21145461
ENPL_HUMAN	HSP90B1	physical	21145461
K1C9_HUMAN	KRT9	physical	21145461
FUS_HUMAN	FUS	physical	21145461
HS90A_HUMAN	HSP90AA1	physical	21145461
IMDH2_HUMAN	IMPDH2	physical	21145461
K1C24_HUMAN	KRT24	physical	21145461
K22O_HUMAN	KRT76	physical	21145461
LYSC_HUMAN	LYZ	physical	21145461
RBM14_HUMAN	RBM14	physical	21145461
RBM4_HUMAN	RBM4	physical	21145461
RS11_HUMAN	RPS11	physical	21145461
RRP12_HUMAN	RRP12	physical	21145461
ROA2_HUMAN	HNRNPA2B1	physical	21145461
HNRH1_HUMAN	HNRNPH1	physical	21145461
HNRH3_HUMAN	HNRNPH3	physical	21145461
HNRL1_HUMAN	HNRNPUL1	physical	21145461
HS71L_HUMAN	HSPA1L	physical	21145461
8ODP_HUMAN	NUDT1	physical	21145461
RL38_HUMAN	RPL38	physical	21145461
SAMH1_HUMAN	SAMHD1	physical	21145461
TBB4B_HUMAN	TUBB4B	physical	21145461
DCAF7_HUMAN	DCAF7	physical	21145461
DDX3X_HUMAN	DDX3X	physical	21145461
DDX5_HUMAN	DDX5	physical	21145461
EF1A2_HUMAN	EEF1A2	physical	21145461
HNRPD_HUMAN	HNRNPD	physical	21145461
HNRPF_HUMAN	HNRNPF	physical	21145461
GRP78_HUMAN	HSPA5	physical	21145461
GRP75_HUMAN	HSPA9	physical	21145461
K2C75_HUMAN	KRT75	physical	21145461
NUCL_HUMAN	NCL	physical	21145461
NFKB1_HUMAN	NFKB1	physical	21145461
NPM_HUMAN	NPM1	physical	21145461
PABP1_HUMAN	PABPC1	physical	21145461
PWP1_HUMAN	PWP1	physical	21145461
RL11_HUMAN	RPL11	physical	21145461
RLA2_HUMAN	RPLP2	physical	21145461
RS4X_HUMAN	RPS4X	physical	21145461
SMD1_HUMAN	SNRPD1	physical	21145461
RBP56_HUMAN	TAF15	physical	21145461
TBA1C_HUMAN	TUBA1C	physical	21145461
TBB5_HUMAN	TUBB	physical	21145461
ACTB_HUMAN	ACTB	physical	21145461
C1QBP_HUMAN	C1QBP	physical	21145461
CLH2_HUMAN	CLTCL1	physical	21145461
EF2_HUMAN	EEF2	physical	21145461
G3P_HUMAN	GAPDH	physical	21145461
ROAA_HUMAN	HNRNPAB	physical	21145461
HNRDL_HUMAN	HNRNPDL	physical	21145461
K2C5_HUMAN	KRT5	physical	21145461
PRDX1_HUMAN	PRDX1	physical	21145461
RL15_HUMAN	RPL15	physical	21145461
RL18_HUMAN	RPL18	physical	21145461
RL23_HUMAN	RPL23	physical	21145461
RL24_HUMAN	RPL24	physical	21145461
RL31_HUMAN	RPL31	physical	21145461
HNRH2_HUMAN	HNRNPH2	physical	21145461
RL4_HUMAN	RPL4	physical	21145461
RL6_HUMAN	RPL6	physical	21145461
RL8_HUMAN	RPL8	physical	21145461
RLA1_HUMAN	RPLP1	physical	21145461
RS14_HUMAN	RPS14	physical	21145461
RS15A_HUMAN	RPS15A	physical	21145461
RS2_HUMAN	RPS2	physical	21145461
RS20_HUMAN	RPS20	physical	21145461
SDHA_HUMAN	SDHA	physical	21145461
ADT2_HUMAN	SLC25A5	physical	21145461
RU17_HUMAN	SNRNP70	physical	21145461
RU1C_HUMAN	SNRPC	physical	21145461
HNRPQ_HUMAN	SYNCRIP	physical	21145461
TIAR_HUMAN	TIAL1	physical	21145461
TBA4A_HUMAN	TUBA4A	physical	21145461
TBB1_HUMAN	TUBB1	physical	21145461
THIO_HUMAN	TXN	physical	21145461
NOD1_HUMAN	NOD1	physical	17337451
CSN2_HUMAN	COPS2	physical	10903862
CSN7A_HUMAN	COPS7A	physical	10903862
RFWD2_HUMAN	RFWD2	physical	19295130
CSN2_HUMAN	COPS2	physical	19295130
CSN3_HUMAN	COPS3	physical	19295130
CSN4_HUMAN	COPS4	physical	19295130
CSN5_HUMAN	COPS5	physical	19295130
CSN7A_HUMAN	COPS7A	physical	19295130
CSN7B_HUMAN	COPS7B	physical	19295130
CSN8_HUMAN	COPS8	physical	19295130
RBX1_HUMAN	RBX1	physical	19295130
CUL1_HUMAN	CUL1	physical	19295130
SKP1_HUMAN	SKP1	physical	19295130
CUL2_HUMAN	CUL2	physical	19295130
CUL5_HUMAN	CUL5	physical	19295130
ELOB_HUMAN	TCEB2	physical	19295130
ELOC_HUMAN	TCEB1	physical	19295130
LRC14_HUMAN	LRRC14	physical	19295130
CUL3_HUMAN	CUL3	physical	19295130
CUL4A_HUMAN	CUL4A	physical	19295130
CUL4B_HUMAN	CUL4B	physical	19295130
DDB1_HUMAN	DDB1	physical	19295130
DDB2_HUMAN	DDB2	physical	19295130
ERCC8_HUMAN	ERCC8	physical	19295130
DCAF1_HUMAN	VPRBP	physical	19295130
DCA11_HUMAN	DCAF11	physical	19295130
DCA10_HUMAN	DCAF10	physical	19295130
DTL_HUMAN	DTL	physical	19295130
DCAF8_HUMAN	DCAF8	physical	19295130
DDA1_HUMAN	DDA1	physical	19295130
DCA16_HUMAN	DCAF16	physical	19295130
DCA17_HUMAN	DCAF17	physical	19295130
CRBN_HUMAN	CRBN	physical	19295130
TOIP2_HUMAN	TOR1AIP2	physical	19295130
IFG15_HUMAN	TOR1AIP2	physical	19295130
CSN8_HUMAN	COPS8	physical	22939629
1433S_HUMAN	SFN	physical	21625211
CSN5_HUMAN	COPS5	physical	21625211
RFWD2_HUMAN	RFWD2	physical	21625211
P63_HUMAN	TP63	physical	21988832
CSN3_HUMAN	COPS3	physical	22863883
CSN4_HUMAN	COPS4	physical	22863883
CUL4B_HUMAN	CUL4B	physical	22863883
NEDD8_HUMAN	NEDD8	physical	25144743
CDN1B_HUMAN	CDKN1B	physical	25945542
CSN8_HUMAN	COPS8	physical	26186194
CSN2_HUMAN	COPS2	physical	26186194
CSN1_HUMAN	GPS1	physical	26186194
CUL4B_HUMAN	CUL4B	physical	26186194
CUL4A_HUMAN	CUL4A	physical	26186194
CSN4_HUMAN	COPS4	physical	26186194
CUL2_HUMAN	CUL2	physical	26186194
CSN3_HUMAN	COPS3	physical	26186194
DDB2_HUMAN	DDB2	physical	26186194
CSN7B_HUMAN	COPS7B	physical	26186194
CSN5_HUMAN	COPS5	physical	26186194
RHBT1_HUMAN	RHOBTB1	physical	26186194
CSN7A_HUMAN	COPS7A	physical	26186194
FEM1B_HUMAN	FEM1B	physical	26186194
LLR1_HUMAN	LRR1	physical	26186194
DCA11_HUMAN	DCAF11	physical	26186194
DCAF4_HUMAN	DCAF4	physical	26186194
BTBD1_HUMAN	BTBD1	physical	26186194
BTBD2_HUMAN	BTBD2	physical	26186194
CSN6_HUMAN	COPS6	physical	25242525
CSN8_HUMAN	COPS8	physical	26344197
GCR_HUMAN	NR3C1	physical	12237292
MK01_HUMAN	MAPK1	physical	26267535
CSN3_HUMAN	COPS3	physical	28514442
CSN5_HUMAN	COPS5	physical	28514442
CSN2_HUMAN	COPS2	physical	28514442
CSN7A_HUMAN	COPS7A	physical	28514442
BTBD1_HUMAN	BTBD1	physical	28514442
DDB2_HUMAN	DDB2	physical	28514442
LLR1_HUMAN	LRR1	physical	28514442
DCAF4_HUMAN	DCAF4	physical	28514442
CSN4_HUMAN	COPS4	physical	28514442
CSN1_HUMAN	GPS1	physical	28514442
FEM1B_HUMAN	FEM1B	physical	28514442
RHBT1_HUMAN	RHOBTB1	physical	28514442
DCA11_HUMAN	DCAF11	physical	28514442
CUL4A_HUMAN	CUL4A	physical	28514442
CUL4B_HUMAN	CUL4B	physical	28514442
CUL2_HUMAN	CUL2	physical	28514442
CUL3_HUMAN	CUL3	physical	28514442
BTBD2_HUMAN	BTBD2	physical	28514442
CSN7B_HUMAN	COPS7B	physical	27173435
CSN5_HUMAN	COPS5	physical	27173435
CSN4_HUMAN	COPS4	physical	27173435
UBE3A_HUMAN	UBE3A	physical	26318036

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CSN6_HUMAN

Related Literatures of Post-Translational Modification