LYSC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LYSC_HUMAN
• UniProt AC: P61626
• Protein Name: Lysozyme C
• Gene Name: LYZ
• Organism: Homo sapiens (Human).
• Sequence Length: 148
• Subcellular Localization: Secreted.
• Protein Description: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents..
• Protein Sequence: MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	KRLGMDGYRGISLAN HHHCCCCCCCHHHHH	11.03	22817900
48	S-nitrosylation	ISLANWMCLAKWESG HHHHHHHHHHHHHCC	2.24	25040305
56	Phosphorylation	LAKWESGYNTRATNY HHHHHCCCCCCCCCC	23.73	-
58	O-linked_Glycosylation	KWESGYNTRATNYNA HHHCCCCCCCCCCCC	17.13	OGP
88	O-linked_Glycosylation	YWCNDGKTPGAVNAC EECCCCCCCCHHHHH	32.27	OGP

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LYSC_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LYSC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LYSC_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of LYSC_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 105200: Amyloidosis 8 (AMYL8)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.