| UniProt ID | CKS1_HUMAN | |
|---|---|---|
| UniProt AC | P61024 | |
| Protein Name | Cyclin-dependent kinases regulatory subunit 1 | |
| Gene Name | CKS1B | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 79 | |
| Subcellular Localization | ||
| Protein Description | Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.. | |
| Protein Sequence | MSHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPLPKKPKK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MSHKQIYYS ------CCCCCEECC | 39.12 | 22814378 | |
| 4 | Ubiquitination | ----MSHKQIYYSDK ----CCCCCEECCCC | 30.96 | 21890473 | |
| 4 | Acetylation | ----MSHKQIYYSDK ----CCCCCEECCCC | 30.96 | 27452117 | |
| 7 | Phosphorylation | -MSHKQIYYSDKYDD -CCCCCEECCCCCCC | 8.40 | 28102081 | |
| 8 | Phosphorylation | MSHKQIYYSDKYDDE CCCCCEECCCCCCCC | 16.42 | 22817900 | |
| 9 | Phosphorylation | SHKQIYYSDKYDDEE CCCCEECCCCCCCCC | 15.62 | - | |
| 11 | Ubiquitination | KQIYYSDKYDDEEFE CCEECCCCCCCCCCE | 44.64 | - | |
| 11 | Acetylation | KQIYYSDKYDDEEFE CCEECCCCCCCCCCE | 44.64 | 27452117 | |
| 12 | Phosphorylation | QIYYSDKYDDEEFEY CEECCCCCCCCCCEE | 33.35 | 22817900 | |
| 19 | Phosphorylation | YDDEEFEYRHVMLPK CCCCCCEEEEEECHH | 16.02 | 20393185 | |
| 26 | Ubiquitination | YRHVMLPKDIAKLVP EEEEECHHHHHHHCC | 58.78 | - | |
| 26 | Acetylation | YRHVMLPKDIAKLVP EEEEECHHHHHHHCC | 58.78 | 27452117 | |
| 30 | Acetylation | MLPKDIAKLVPKTHL ECHHHHHHHCCCCCC | 50.80 | 25953088 | |
| 30 | Ubiquitination | MLPKDIAKLVPKTHL ECHHHHHHHCCCCCC | 50.80 | - | |
| 30 | 2-Hydroxyisobutyrylation | MLPKDIAKLVPKTHL ECHHHHHHHCCCCCC | 50.80 | - | |
| 34 | Acetylation | DIAKLVPKTHLMSES HHHHHCCCCCCCCHH | 40.89 | 27452117 | |
| 34 | Ubiquitination | DIAKLVPKTHLMSES HHHHHCCCCCCCCHH | 40.89 | - | |
| 38 | Sulfoxidation | LVPKTHLMSESEWRN HCCCCCCCCHHHHHH | 3.03 | 28183972 | |
| 39 | Phosphorylation | VPKTHLMSESEWRNL CCCCCCCCHHHHHHH | 44.31 | 29978859 | |
| 41 | Phosphorylation | KTHLMSESEWRNLGV CCCCCCHHHHHHHCC | 34.84 | 29978859 | |
| 51 | Phosphorylation | RNLGVQQSQGWVHYM HHHCCCCCCCEEEEE | 17.36 | 22617229 | |
| 57 | Phosphorylation | QSQGWVHYMIHEPEP CCCCEEEEEECCCCC | 6.53 | 28450419 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CKS1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CKS1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CKS1_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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