dbPTM

GDPP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GDPP1_HUMAN
UniProt AC	Q6ZNW5
Protein Name	GDP-D-glucose phosphorylase 1
Gene Name	GDPGP1
Organism	Homo sapiens (Human).
Sequence Length	385
Subcellular Localization	Cytoplasm.
Protein Description	Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells..
Protein Sequence	MALPHDSNETSYLLPPNNEDWGRQTIPDFVYGQKDLMAEGIQWPRNAPGIPDALPQSPFDAALCSAWKQRVELGLFRYRLRELQTQILPGAVGFVAQLNVERGVQRRPPQTIKSVRQAFDPVQFNFNKIRPGEVLFRLHREPDLPGTLLQEDILVVINVSPLEWGHVLLVPEPARQLPQRLLPGALRAGIEAVLLSLHPGFRVGFNSLGGLASVNHLHLHGYYLAHRLPVEQAPSEPLDPGGHLHLLQDLPAPGFLFYTRGPGPDLESLISRVCRATDYLTDHEIAHNLFVTRGAPPGKTSPSSALTGVRVILWARKSSFGIKDGEAFNVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCRLPPSQAEDVQAALVALMSQEEQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
128	Ubiquitination	PVQFNFNKIRPGEVL CEECCCCCCCCCCCE	35.63	-
268	Phosphorylation	GPGPDLESLISRVCR CCCCCHHHHHHHHHH	38.00	24719451
271	Phosphorylation	PDLESLISRVCRATD CCHHHHHHHHHHHHH	24.77	24719451
299	Ubiquitination	TRGAPPGKTSPSSAL CCCCCCCCCCHHHHH	52.16	-
304	Phosphorylation	PGKTSPSSALTGVRV CCCCCHHHHHHHHEE	30.59	-
344	Phosphorylation	GHLPVKTSQDFSSLT CCCCCCCCCCHHHHH	23.26	25332170

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GDPP1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GDPP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GDPP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
MESH1_HUMAN	HDDC3	physical	26344197
LHPP_HUMAN	LHPP	physical	26344197

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GDPP1_HUMAN

Related Literatures of Post-Translational Modification