DC4L1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DC4L1_HUMAN
• UniProt AC: Q3SXM0
• Protein Name: DDB1- and CUL4-associated factor 4-like protein 1
• Gene Name: DCAF4L1
• Organism: Homo sapiens (Human).
• Sequence Length: 396
• Protein Sequence: MEAERLRLLEEEAKLKKVARMGFNASSMLRKSQLGFLNVTSYSRLANELRVSCMERKKVQIRSLDPSSLASDRFNFILASTNSDQLFVVNQVEVEGSKYGIISLRTLKIPSFHVYVLRNLYVPNRKVKSLCWASLNQLDSHVLLCFEGITDAPSCAVLLPASRFLSVHTRVNQPGMLCSFQIPEAWSCAWSLNTRAYHCFSAGLSQQVLLTSVATGHQQSFDTSSDVLAQQFASTAPLLFNGCRSGEIFAIDLRCRNRGKGWRATRLFHDSAVTSVQILQEEQCLMASDMTGKIKLWDLRATKCVRQYEGHVNESAYLPLHVHEEEGIVVAVGQDCYTRIWSLHDAHLLRTIPSPYSASEDDIPSVAFASRLGGIRGAAPGLLMAVRQDLYCFPFS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Phosphorylation	ARMGFNASSMLRKSQ HHCCCCHHHHHHHHH	19.86	28509920
27	Phosphorylation	RMGFNASSMLRKSQL HCCCCHHHHHHHHHC	21.30	19664995
99	Phosphorylation	VEVEGSKYGIISLRT EEECCCEEEEEEEEE	18.43	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DC4L1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DC4L1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DC4L1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CUL4A_HUMAN	CUL4A	physical	26186194
CUL4A_HUMAN	CUL4A	physical	28514442
CUL4B_HUMAN	CUL4B	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.