dbPTM

RBP56_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RBP56_HUMAN
UniProt AC	Q92804
Protein Name	TATA-binding protein-associated factor 2N
Gene Name	TAF15
Organism	Homo sapiens (Human).
Sequence Length	592
Subcellular Localization	Nucleus . Cytoplasm . Shuttles from the nucleus to the cytoplasm.
Protein Description	RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II)..
Protein Sequence	MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MSDSGSYGQSG ----CCCCCCCCCCC	23.49	25137130
28	Ubiquitination	GNPGSQGYGQASQSY CCCCCCCCCCCCCCC	9.83	22053931
37	Ubiquitination	QASQSYSGYGQTTDS CCCCCCCCCCCCCCC	23.51	21890473
50	Phosphorylation	DSSYGQNYSGYSSYG CCCCCCCCCCCCCCC	8.79	-
70	Phosphorylation	YSQSYGGYENQKQSS CCCCCCCCCCCCCCC	13.82	-
76	Phosphorylation	GYENQKQSSYSQQPY CCCCCCCCCCCCCCC	37.97	21945579
76 (in isoform 2)	Phosphorylation	-	37.97	-
77	Phosphorylation	YENQKQSSYSQQPYN CCCCCCCCCCCCCCC	26.72	21945579
78	Phosphorylation	ENQKQSSYSQQPYNN CCCCCCCCCCCCCCC	18.75	21945579
79	Phosphorylation	NQKQSSYSQQPYNNQ CCCCCCCCCCCCCCH	25.04	21945579
83	Phosphorylation	SSYSQQPYNNQGQQQ CCCCCCCCCCHHHHH	23.54	21945579
94	Phosphorylation	GQQQNMESSGSQGGR HHHHHHHCCCCCCCC	29.27	21945579
94 (in isoform 2)	Phosphorylation	-	29.27	-
95	Phosphorylation	QQQNMESSGSQGGRA HHHHHHCCCCCCCCC	29.20	21945579
97	Phosphorylation	QNMESSGSQGGRAPS HHHHCCCCCCCCCCC	27.83	21945579
104	Phosphorylation	SQGGRAPSYDQPDYG CCCCCCCCCCCCCCC	40.12	24275569
110	Phosphorylation	PSYDQPDYGQQDSYD CCCCCCCCCCCCCCC	24.42	20736484
115	Phosphorylation	PDYGQQDSYDQQSGY CCCCCCCCCCCCCCC	26.69	30576142
116	Phosphorylation	DYGQQDSYDQQSGYD CCCCCCCCCCCCCCC	26.51	30576142
120	Phosphorylation	QDSYDQQSGYDQHQG CCCCCCCCCCCCCCC	33.42	22817901
122	Phosphorylation	SYDQQSGYDQHQGSY CCCCCCCCCCCCCCC	20.06	30576142
128	Phosphorylation	GYDQHQGSYDEQSNY CCCCCCCCCCCCCCC	23.88	30576142
133	Phosphorylation	QGSYDEQSNYDQQHD CCCCCCCCCCHHHCC	35.00	30576142
135	Phosphorylation	SYDEQSNYDQQHDSY CCCCCCCCHHHCCHH	22.00	-
142	Phosphorylation	YDQQHDSYSQNQQSY CHHHCCHHHHHHHHH	21.97	-
149	Phosphorylation	YSQNQQSYHSQRENY HHHHHHHHHHCHHHC	10.93	-
156	Phosphorylation	YHSQRENYSHHTQDD HHHCHHHCCCCCCCH	12.48	28796482
157	Phosphorylation	HSQRENYSHHTQDDR HHCHHHCCCCCCCHH	22.00	28796482
160	Phosphorylation	RENYSHHTQDDRRDV HHHCCCCCCCHHHCH	28.41	29978859
164	Methylation	SHHTQDDRRDVSRYG CCCCCCHHHCHHHHC	45.01	82955195
170	Phosphorylation	DRRDVSRYGEDNRGY HHHCHHHHCCCCCCC	19.84	-
175	Methylation	SRYGEDNRGYGGSQG HHHCCCCCCCCCCCC	52.62	54559741
177	Phosphorylation	YGEDNRGYGGSQGGG HCCCCCCCCCCCCCC	18.31	25839225
180	Phosphorylation	DNRGYGGSQGGGRGR CCCCCCCCCCCCCCC	22.68	25627689
185	Dimethylation	GGSQGGGRGRGGYDK CCCCCCCCCCCCCCC	34.60	-
185	Methylation	GGSQGGGRGRGGYDK CCCCCCCCCCCCCCC	34.60	16288479
187	Dimethylation	SQGGGRGRGGYDKDG CCCCCCCCCCCCCCC	33.72	-
187	Methylation	SQGGGRGRGGYDKDG CCCCCCCCCCCCCCC	33.72	16288487
190	Phosphorylation	GGRGRGGYDKDGRGP CCCCCCCCCCCCCCC	23.73	-
192	Trimethylation	RGRGGYDKDGRGPMT CCCCCCCCCCCCCCC	54.31	-
192	Methylation	RGRGGYDKDGRGPMT CCCCCCCCCCCCCCC	54.31	23748837
195	Methylation	GGYDKDGRGPMTGSS CCCCCCCCCCCCCCC	57.06	54559787
199	Phosphorylation	KDGRGPMTGSSGGDR CCCCCCCCCCCCCCC	36.73	-
201	Phosphorylation	GRGPMTGSSGGDRGG CCCCCCCCCCCCCCC	19.35	-
202	Phosphorylation	RGPMTGSSGGDRGGF CCCCCCCCCCCCCCC	48.41	-
203	Methylation	GPMTGSSGGDRGGFK CCCCCCCCCCCCCCC	43.66	15782174
203 (in isoform 2)	Methylation	-	43.66	-
206	Asymmetric dimethylarginine	TGSSGGDRGGFKNFG CCCCCCCCCCCCCCC	50.86	-
206	Methylation	TGSSGGDRGGFKNFG CCCCCCCCCCCCCCC	50.86	24129315
206	Ubiquitination	TGSSGGDRGGFKNFG CCCCCCCCCCCCCCC	50.86	22053931
210	"N6,N6-dimethyllysine"	GGDRGGFKNFGGHRD CCCCCCCCCCCCCCC	55.42	-
210	Methylation	GGDRGGFKNFGGHRD CCCCCCCCCCCCCCC	55.42	23748837
215	Ubiquitination	GFKNFGGHRDYGPRT CCCCCCCCCCCCCCC	21.59	21890473
218	Phosphorylation	NFGGHRDYGPRTDAD CCCCCCCCCCCCCCC	29.05	25394399
219 (in isoform 2)	Phosphorylation	-	14.98	-
222	Phosphorylation	HRDYGPRTDADSESD CCCCCCCCCCCCCCC	38.38	26503892
223	Phosphorylation	RDYGPRTDADSESDN CCCCCCCCCCCCCCC	50.05	32142685
223 (in isoform 2)	Phosphorylation	-	50.05	-
225 (in isoform 2)	Phosphorylation	-	56.60	-
226	Phosphorylation	GPRTDADSESDNSDN CCCCCCCCCCCCCCC	40.49	30278072
228	Phosphorylation	RTDADSESDNSDNNT CCCCCCCCCCCCCCE	46.15	30278072
228 (in isoform 2)	Phosphorylation	-	46.15	-
231	Phosphorylation	ADSESDNSDNNTIFV CCCCCCCCCCCEEEE	46.86	30278072
235	Phosphorylation	SDNSDNNTIFVQGLG CCCCCCCEEEEECCC	23.26	28176443
246	Phosphorylation	QGLGEGVSTDQVGEF ECCCCCCCHHHHHHH	36.80	20873877
247	Phosphorylation	GLGEGVSTDQVGEFF CCCCCCCHHHHHHHH	28.22	20873877
258	Ubiquitination	GEFFKQIGIIKTNKK HHHHHHHCCEEECCC	17.05	29967540
261	Ubiquitination	FKQIGIIKTNKKTGK HHHHCCEEECCCCCC	44.09	29967540
262	Ubiquitination	KQIGIIKTNKKTGKP HHHCCEEECCCCCCC	41.69	29967540
265	Acetylation	GIIKTNKKTGKPMIN CCEEECCCCCCCCEE	65.66	19608861
265	Sumoylation	GIIKTNKKTGKPMIN CCEEECCCCCCCCEE	65.66	28112733
265	Ubiquitination	GIIKTNKKTGKPMIN CCEEECCCCCCCCEE	65.66	33845483
265 (in isoform 2)	Acetylation	-	65.66	-
268	Acetylation	KTNKKTGKPMINLYT EECCCCCCCCEEEEE	36.32	19608861
268	Sumoylation	KTNKKTGKPMINLYT EECCCCCCCCEEEEE	36.32	28112733
268	Ubiquitination	KTNKKTGKPMINLYT EECCCCCCCCEEEEE	36.32	33845483
277	"N6,N6-dimethyllysine"	MINLYTDKDTGKPKG CEEEEECCCCCCCCC	49.76	-
277	2-Hydroxyisobutyrylation	MINLYTDKDTGKPKG CEEEEECCCCCCCCC	49.76	-
277	Acetylation	MINLYTDKDTGKPKG CEEEEECCCCCCCCC	49.76	26051181
277	Methylation	MINLYTDKDTGKPKG CEEEEECCCCCCCCC	49.76	-
277	Ubiquitination	MINLYTDKDTGKPKG CEEEEECCCCCCCCC	49.76	-
280	Ubiquitination	LYTDKDTGKPKGEAT EEECCCCCCCCCEEE	55.17	33845483
281	Acetylation	YTDKDTGKPKGEATV EECCCCCCCCCEEEE	45.72	26051181
283	Sumoylation	DKDTGKPKGEATVSF CCCCCCCCCEEEEEE	73.24	-
283	Ubiquitination	DKDTGKPKGEATVSF CCCCCCCCCEEEEEE	73.24	33845483
287	Phosphorylation	GKPKGEATVSFDDPP CCCCCEEEEEECCCC	16.63	25850435
289	Phosphorylation	PKGEATVSFDDPPSA CCCEEEEEECCCCCC	20.71	25159151
294	Ubiquitination	TVSFDDPPSAKAAID EEEECCCCCCCEEEE	54.64	22053931
294 (in isoform 2)	Ubiquitination	-	54.64	21890473
295	Phosphorylation	VSFDDPPSAKAAIDW EEECCCCCCCEEEEC	48.03	25159151
297	Ubiquitination	FDDPPSAKAAIDWFD ECCCCCCCEEEECCC	42.56	21890473
297	Sumoylation	FDDPPSAKAAIDWFD ECCCCCCCEEEECCC	42.56	-
297	Ubiquitination	FDDPPSAKAAIDWFD ECCCCCCCEEEECCC	42.56	22053931
297 (in isoform 1)	Ubiquitination	-	42.56	21890473
303	Ubiquitination	AKAAIDWFDGKEFHG CCEEEECCCCCEECC	8.66	21890473
303 (in isoform 2)	Ubiquitination	-	8.66	21890473
306	Ubiquitination	AIDWFDGKEFHGNII EEECCCCCEECCCEE	60.08	21890473
306	2-Hydroxyisobutyrylation	AIDWFDGKEFHGNII EEECCCCCEECCCEE	60.08	-
306	Acetylation	AIDWFDGKEFHGNII EEECCCCCEECCCEE	60.08	26051181
306	Ubiquitination	AIDWFDGKEFHGNII EEECCCCCEECCCEE	60.08	29967540
306 (in isoform 1)	Ubiquitination	-	60.08	21890473
311	Ubiquitination	DGKEFHGNIIKVSFA CCCEECCCEEEEEEE	25.00	33845483
314	Ubiquitination	EFHGNIIKVSFATRR EECCCEEEEEEECCC	28.20	33845483
320	Methylation	IKVSFATRRPEFMRG EEEEEECCCCHHHCC	49.04	-
321	Methylation	KVSFATRRPEFMRGG EEEEECCCCHHHCCC	30.64	97816469
326	Dimethylation	TRRPEFMRGGGSGGG CCCCHHHCCCCCCCC	46.02	-
326	Methylation	TRRPEFMRGGGSGGG CCCCHHHCCCCCCCC	46.02	18583751
330	Phosphorylation	EFMRGGGSGGGRRGR HHHCCCCCCCCCCCC	37.22	-
334	Methylation	GGGSGGGRRGRGGYR CCCCCCCCCCCCCCC	40.95	97816459
335	Methylation	GGSGGGRRGRGGYRG CCCCCCCCCCCCCCC	42.30	24411387
349	Methylation	GRGGFQGRGGDPKSG CCCCCCCCCCCCCCC	34.83	115387919
354	Acetylation	QGRGGDPKSGDWVCP CCCCCCCCCCCEECC	72.34	26051181
354	Ubiquitination	QGRGGDPKSGDWVCP CCCCCCCCCCCEECC	72.34	-
355	Phosphorylation	GRGGDPKSGDWVCPN CCCCCCCCCCEECCC	47.58	26714015
375	Phosphorylation	MNFARRNSCNQCNEP CCHHHHCCCCCCCCC	16.78	29255136
383	Methylation	CNQCNEPRPEDSRPS CCCCCCCCCCCCCCC	40.85	81121021
387	Phosphorylation	NEPRPEDSRPSGGDF CCCCCCCCCCCCCCC	44.41	20873877
388	Methylation	EPRPEDSRPSGGDFR CCCCCCCCCCCCCCC	41.55	54559763
395	Methylation	RPSGGDFRGRGYGGE CCCCCCCCCCCCCCC	38.34	12019843
397	Dimethylation	SGGDFRGRGYGGERG CCCCCCCCCCCCCCC	30.79	-
397	Methylation	SGGDFRGRGYGGERG CCCCCCCCCCCCCCC	30.79	30761291
403	Methylation	GRGYGGERGYRGRGG CCCCCCCCCCCCCCC	51.20	30761297
412	Methylation	YRGRGGRGGDRGGYG CCCCCCCCCCCCCCC	45.70	15782174
412 (in isoform 2)	Methylation	-	45.70	-
415	Methylation	RGGRGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	24395775
418	Phosphorylation	RGGDRGGYGGDRSGG CCCCCCCCCCCCCCC	22.28	-
422	Methylation	RGGYGGDRSGGGYGG CCCCCCCCCCCCCCC	40.24	97770775
423	Phosphorylation	GGYGGDRSGGGYGGD CCCCCCCCCCCCCCC	46.67	23403867
427	Phosphorylation	GDRSGGGYGGDRSSG CCCCCCCCCCCCCCC	22.62	24732914
429 (in isoform 2)	Phosphorylation	-	20.76	-
430 (in isoform 2)	Phosphorylation	-	42.81	-
431	Methylation	GGGYGGDRSSGGGYS CCCCCCCCCCCCCCC	35.68	24129315
432	Phosphorylation	GGYGGDRSSGGGYSG CCCCCCCCCCCCCCC	37.77	21955146
433	Phosphorylation	GYGGDRSSGGGYSGD CCCCCCCCCCCCCCC	42.21	22617229
434 (in isoform 2)	Phosphorylation	-	34.49	-
435	Phosphorylation	GGDRSSGGGYSGDRS CCCCCCCCCCCCCCC	33.54	33259812
437	Phosphorylation	DRSSGGGYSGDRSGG CCCCCCCCCCCCCCC	16.86	22115753
438	Phosphorylation	RSSGGGYSGDRSGGG CCCCCCCCCCCCCCC	37.18	22115753
441	Methylation	GGGYSGDRSGGGYGG CCCCCCCCCCCCCCC	40.50	80700905
442	Phosphorylation	GGYSGDRSGGGYGGD CCCCCCCCCCCCCCC	46.67	23403867
446	Phosphorylation	GDRSGGGYGGDRSGG CCCCCCCCCCCCCCC	22.62	23403867
450	Methylation	GGGYGGDRSGGGYGG CCCCCCCCCCCCCCC	40.24	31118111
451	Phosphorylation	GGYGGDRSGGGYGGD CCCCCCCCCCCCCCC	46.67	21406692
455	Phosphorylation	GDRSGGGYGGDRGGG CCCCCCCCCCCCCCC	22.62	18083107
456	Methylation	DRSGGGYGGDRGGGY CCCCCCCCCCCCCCC	34.50	15782174
456 (in isoform 2)	Methylation	-	34.50	-
459	Dimethylation	GGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	-
459	Methylation	GGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	24129315
463	Phosphorylation	GGDRGGGYGGDRGGG CCCCCCCCCCCCCCC	22.62	25839225
464 (in isoform 2)	Methylation	-	34.50	-
467	Dimethylation	GGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	-
467	Methylation	GGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	12019863
471	Phosphorylation	GGDRGGGYGGDRGGG CCCCCCCCCCCCCCC	22.62	18083107
472	Methylation	GDRGGGYGGDRGGGY CCCCCCCCCCCCCCC	34.50	15782174
472 (in isoform 2)	Methylation	-	34.50	-
475	Dimethylation	GGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	-
475	Methylation	GGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	24129315
479	Phosphorylation	GGDRGGGYGGDRGGY CCCCCCCCCCCCCCC	22.62	18083107
480	Methylation	GDRGGGYGGDRGGYG CCCCCCCCCCCCCCC	34.50	15782174
480 (in isoform 2)	Methylation	-	34.50	-
483	Dimethylation	GGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	-
483	Methylation	GGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	12019883
486	Phosphorylation	YGGDRGGYGGDRGGG CCCCCCCCCCCCCCC	22.28	18083107
487	Methylation	GGDRGGYGGDRGGGY CCCCCCCCCCCCCCC	34.50	15782174
487 (in isoform 2)	Methylation	-	34.50	-
490	Dimethylation	RGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	-
490	Methylation	RGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	12019893
494	Phosphorylation	GGDRGGGYGGDRGGY CCCCCCCCCCCCCCC	22.62	18083107
495	Methylation	GDRGGGYGGDRGGYG CCCCCCCCCCCCCCC	34.50	15782174
495 (in isoform 2)	Methylation	-	34.50	-
498	Dimethylation	GGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	-
498	Methylation	GGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	12019901
501	Phosphorylation	YGGDRGGYGGDRGGY CCCCCCCCCCCCCCC	22.28	18083107
502	Methylation	GGDRGGYGGDRGGYG CCCCCCCCCCCCCCC	34.50	15782174
502 (in isoform 2)	Methylation	-	34.50	-
505	Dimethylation	RGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	-
505	Methylation	RGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	24383667
508	Phosphorylation	YGGDRGGYGGDRGGY CCCCCCCCCCCCCCC	22.28	18083107
509 (in isoform 2)	Methylation	-	34.50	-
512	Dimethylation	RGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	-
512	Methylation	RGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	24383673
515	Phosphorylation	YGGDRGGYGGDRGGY CCCCCCCCCCCCCCC	22.28	18083107
516 (in isoform 2)	Methylation	-	34.50	-
519	Dimethylation	RGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	-
519	Methylation	RGGYGGDRGGYGGDR CCCCCCCCCCCCCCC	43.65	24383679
522	Phosphorylation	YGGDRGGYGGDRSRG CCCCCCCCCCCCCCC	22.28	22210691
527	Phosphorylation	GGYGGDRSRGGYGGD CCCCCCCCCCCCCCC	39.76	22210691
528	Asymmetric dimethylarginine	GYGGDRSRGGYGGDR CCCCCCCCCCCCCCC	43.37	-
528	Methylation	GYGGDRSRGGYGGDR CCCCCCCCCCCCCCC	43.37	19124016
531	Phosphorylation	GDRSRGGYGGDRGGG CCCCCCCCCCCCCCC	22.28	-
532	Methylation	DRSRGGYGGDRGGGS CCCCCCCCCCCCCCC	34.50	15782174
532 (in isoform 2)	Methylation	-	34.50	-
535	Asymmetric dimethylarginine	RGGYGGDRGGGSGYG CCCCCCCCCCCCCCC	49.26	-
535	Methylation	RGGYGGDRGGGSGYG CCCCCCCCCCCCCCC	49.26	19124016
545	Methylation	GSGYGGDRSGGYGGD CCCCCCCCCCCCCCC	40.24	115368493
553	Methylation	SGGYGGDRSGGGYGG CCCCCCCCCCCCCCC	40.24	54559757
554	Phosphorylation	GGYGGDRSGGGYGGD CCCCCCCCCCCCCCC	46.67	21406692
558	Phosphorylation	GDRSGGGYGGDRGGG CCCCCCCCCCCCCCC	22.62	18083107
559	Methylation	DRSGGGYGGDRGGGY CCCCCCCCCCCCCCC	34.50	15782174
559 (in isoform 2)	Methylation	-	34.50	-
562	Dimethylation	GGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	-
562	Methylation	GGGYGGDRGGGYGGD CCCCCCCCCCCCCCC	49.26	24129315
566	Phosphorylation	GGDRGGGYGGDRGGY CCCCCCCCCCCCCCC	22.62	25839225
567	Methylation	GDRGGGYGGDRGGYG CCCCCCCCCCCCCCC	34.50	15782174
567 (in isoform 2)	Methylation	-	34.50	-
570	Asymmetric dimethylarginine	GGGYGGDRGGYGGKM CCCCCCCCCCCCCCC	43.65	-
570	Methylation	GGGYGGDRGGYGGKM CCCCCCCCCCCCCCC	43.65	19124016
576	Trimethylation	DRGGYGGKMGGRNDY CCCCCCCCCCCCCCC	29.97	-
576	Methylation	DRGGYGGKMGGRNDY CCCCCCCCCCCCCCC	29.97	23748837
580	Methylation	YGGKMGGRNDYRNDQ CCCCCCCCCCCCCCC	27.41	54559779
583	Phosphorylation	KMGGRNDYRNDQRNR CCCCCCCCCCCCCCC	18.18	-
588	Methylation	NDYRNDQRNRPY--- CCCCCCCCCCCC---	43.94	115387927
590	Methylation	YRNDQRNRPY----- CCCCCCCCCC-----	33.80	115387935

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RBP56_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
206	R	Methylation
Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RBP56_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SAFB1_HUMAN	SAFB	physical	15066997
TAF7_HUMAN	TAF7	physical	9488465
TAF5_HUMAN	TAF5	physical	9488465
TAF13_HUMAN	TAF13	physical	9488465
TAF11_HUMAN	TAF11	physical	9488465
RPB3_HUMAN	POLR2C	physical	9488465
RPB7_HUMAN	POLR2G	physical	9488465
RPAB1_HUMAN	POLR2E	physical	9488465
SF01_HUMAN	SF1	physical	9660765
RPB1_HUMAN	POLR2A	physical	8890175
TPR_HUMAN	TPR	physical	22939629
S30BP_HUMAN	SAP30BP	physical	22939629
RN168_HUMAN	RNF168	physical	22939629
SCRB2_HUMAN	SCARB2	physical	22939629
TPM2_HUMAN	TPM2	physical	22939629
TMED9_HUMAN	TMED9	physical	22939629
HS104_YEAST	HSP104	genetic	25062688
THIM_HUMAN	ACAA2	physical	26344197
DNPEP_HUMAN	DNPEP	physical	28514442
KLHL8_HUMAN	KLHL8	physical	28514442
ANM1_HUMAN	PRMT1	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RBP56_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-268, AND MASS SPECTROMETRY.	19608861 [Abstract]
Methylation
Reference	PubMed
"PRMT1 mediated methylation of TAF15 is required for its positive generegulatory function."; Jobert L., Argentini M., Tora L.; Exp. Cell Res. 315:1273-1286(2009). Cited for: FUNCTION, METHYLATION AT ARG-206 BY PRMT1, MASS SPECTROMETRY, ANDSUBCELLULAR LOCATION.	19124016 [Abstract]
"Identifying and quantifying in vivo methylation sites by heavy methylSILAC."; Ong S.E., Mittler G., Mann M.; Nat. Methods 1:119-126(2004). Cited for: METHYLATION [LARGE SCALE ANALYSIS] AT ARG-206, AND MASS SPECTROMETRY.	15782174 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-226 AND SER-231, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-97, AND MASSSPECTROMETRY.	17525332 [Abstract]

show