| UniProt ID | OXDD_HUMAN | |
|---|---|---|
| UniProt AC | Q99489 | |
| Protein Name | D-aspartate oxidase | |
| Gene Name | DDO | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 341 | |
| Subcellular Localization | Peroxisome. | |
| Protein Description | Selectively catalyzes the oxidative deamination of D-aspartate and its N-methylated derivative, N-methyl D-aspartate.. | |
| Protein Sequence | MDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTPIHTQKQWFRETFNHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLGFRKMTEAELKKFPQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDLWELHPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHVTLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPVVHHYGHGSGGISVHWGTALEAARLVSECVHALRTPIPKSNL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 17 | Phosphorylation | GAGVVGLSTAVCISK CCCHHHHHHHHHHHH | 14.37 | 24732914 | |
| 18 | Phosphorylation | AGVVGLSTAVCISKL CCHHHHHHHHHHHHH | 28.31 | 24732914 | |
| 23 | Phosphorylation | LSTAVCISKLVPRCS HHHHHHHHHHCCCCE | 18.14 | 24732914 | |
| 24 | Ubiquitination | STAVCISKLVPRCSV HHHHHHHHHCCCCEE | 33.32 | - | |
| 39 | Phosphorylation | TIISDKFTPDTTSDV EEECCCCCCCCCCCC | 26.45 | - | |
| 81 (in isoform 2) | Phosphorylation | - | 20.61 | 24719451 | |
| 81 | Phosphorylation | HLFAIANSAEAGDAG HHHHHHHHHCCCCCC | 20.61 | - | |
| 93 (in isoform 2) | Phosphorylation | - | 40.45 | 24719451 | |
| 109 | Phosphorylation | PTEEVPFWADVVLGF CCCCCCCHHHHHHCC | 5.86 | 24719451 | |
| 109 (in isoform 4) | Phosphorylation | - | 5.86 | 24719451 | |
| 118 (in isoform 1) | Ubiquitination | - | 48.16 | 21906983 | |
| 118 | Ubiquitination | DVVLGFRKMTEAELK HHHHCCCCCCHHHHH | 48.16 | 21906983 | |
| 121 | Phosphorylation | LGFRKMTEAELKKFP HCCCCCCHHHHHHCC | 36.33 | 24719451 | |
| 121 (in isoform 4) | Phosphorylation | - | 36.33 | 24719451 | |
| 125 (in isoform 1) | Ubiquitination | - | 43.82 | 21906983 | |
| 125 | Ubiquitination | KMTEAELKKFPQYVF CCCHHHHHHCCHHHH | 43.82 | 21906983 | |
| 146 | Ubiquitination | LKCECPAYLPWLEKR EEEECCCCHHHHHHH | 9.84 | - | |
| 153 | Ubiquitination | YLPWLEKRIKGSGGW CHHHHHHHCCCCCCC | 26.86 | - | |
| 225 | Phosphorylation | GSGLTYIYPGTSHVT CCCCEEECCCCCEEE | 5.79 | 24719451 | |
| 256 | Phosphorylation | ENSREILSRCCALEP HHHHHHHHHHHHCCH | 29.00 | 24719451 | |
| 334 | Phosphorylation | ECVHALRTPIPKSNL HHHHHHCCCCCCCCC | 26.81 | 27251275 | |
| 362 | Phosphorylation | ---------------------------- ---------------------------- | 27251275 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of OXDD_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of OXDD_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of OXDD_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PEX5_HUMAN | PEX5 | physical | 9820813 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
